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The map label for this gene is phoP [H]

Identifier: 220932997

GI number: 220932997

Start: 2356669

End: 2357349

Strand: Reverse

Name: phoP [H]

Synonym: Hore_21640

Alternate gene names: 220932997

Gene position: 2357349-2356669 (Counterclockwise)

Preceding gene: 220932998

Following gene: 220932996

Centisome position: 91.44

GC content: 40.09

Gene sequence:

>681_bases
ATGGAGAAAATACTGGTTATAGATGATGAAGAGAATATCAGGGAGCTTATTAAATTTAATTTAGAGACGGCAGGTTACAG
GGTAGAACTGGCCGCTGATGGAGAAGAAGGTTGGGACAGGTTGAATGATTCCATAGATTTGATTATCCTTGACTTAATGT
TGCCCCGGATTGATGGACTGAGCTTCTGCCGGCAGGTCAGGTCCAATAACCGATTTAAAGATATTCCCATAATCATGTTA
ACTGCTAAAGGGGAAGAAGTGGACAAAATTATTGGGTTAGAAATGGGAGCAGATGATTATATAACCAAACCCTTTAGCCC
CCGGGAACTGGTTGCCAGGATTAAGGCCGTGCTCCGCAGAGTGCAAAAGAATGAAGAAAAGAGTGATAATGAGTTAATAA
AAAAAGCTGATTTTGAATTAGATGTATCCAGTCATGAAGCCCGTAAGGGAGGGGAGGTTTTAAACTTAACCCCTAAAGAA
TTTGATTTATTGCGTCATCTACTGGTAAATTCGGGTAAGGTATTAACCCGTGATATTCTACTTGAAAAAGTCTGGGGCTA
TGAATATGCAGGGGATACCAGAACTGTTGATGTTCATATAAGGAGGTTAAGAAGAAAGATCGGGGATAATTATATTGTTA
CCGTGAGAGGGGTGGGGTATAAATTTGTTAAACTGGAATGA

Upstream 100 bases:

>100_bases
GCCGATATTGCCCACAGTATGACAGAAGCTTTATAAATGTTAAGCCTCCTTTGACAGGGGGCTTTTTTTTGTTATACTTA
AGATAAAGAGGAGGAGTGTT

Downstream 100 bases:

>100_bases
CCTGAGTATTAAAAATCAATTTCTGGTACTATTTATTGTAACCCAGCTTATTATTATGGGGTTGTTATTTATTTATTTTA
ACCATAATGAGAGGGAGTTT

Product: winged helix family two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 226; Mature: 226

Protein sequence:

>226_residues
MEKILVIDDEENIRELIKFNLETAGYRVELAADGEEGWDRLNDSIDLIILDLMLPRIDGLSFCRQVRSNNRFKDIPIIML
TAKGEEVDKIIGLEMGADDYITKPFSPRELVARIKAVLRRVQKNEEKSDNELIKKADFELDVSSHEARKGGEVLNLTPKE
FDLLRHLLVNSGKVLTRDILLEKVWGYEYAGDTRTVDVHIRRLRRKIGDNYIVTVRGVGYKFVKLE

Sequences:

>Translated_226_residues
MEKILVIDDEENIRELIKFNLETAGYRVELAADGEEGWDRLNDSIDLIILDLMLPRIDGLSFCRQVRSNNRFKDIPIIML
TAKGEEVDKIIGLEMGADDYITKPFSPRELVARIKAVLRRVQKNEEKSDNELIKKADFELDVSSHEARKGGEVLNLTPKE
FDLLRHLLVNSGKVLTRDILLEKVWGYEYAGDTRTVDVHIRRLRRKIGDNYIVTVRGVGYKFVKLE
>Mature_226_residues
MEKILVIDDEENIRELIKFNLETAGYRVELAADGEEGWDRLNDSIDLIILDLMLPRIDGLSFCRQVRSNNRFKDIPIIML
TAKGEEVDKIIGLEMGADDYITKPFSPRELVARIKAVLRRVQKNEEKSDNELIKKADFELDVSSHEARKGGEVLNLTPKE
FDLLRHLLVNSGKVLTRDILLEKVWGYEYAGDTRTVDVHIRRLRRKIGDNYIVTVRGVGYKFVKLE

Specific function: Member of the two-component regulatory system phoP/phoR involved in the regulation of alkaline phosphatase genes phoA and phoB and of phosphodiesterase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=225, Percent_Identity=45.7777777777778, Blast_Score=193, Evalue=1e-50,
Organism=Escherichia coli, GI1789809, Length=233, Percent_Identity=45.9227467811159, Blast_Score=181, Evalue=3e-47,
Organism=Escherichia coli, GI1788394, Length=226, Percent_Identity=41.5929203539823, Blast_Score=168, Evalue=2e-43,
Organism=Escherichia coli, GI87082012, Length=229, Percent_Identity=37.9912663755458, Blast_Score=155, Evalue=3e-39,
Organism=Escherichia coli, GI1786784, Length=223, Percent_Identity=39.9103139013453, Blast_Score=153, Evalue=9e-39,
Organism=Escherichia coli, GI1790860, Length=229, Percent_Identity=39.3013100436681, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI2367329, Length=233, Percent_Identity=40.7725321888412, Blast_Score=147, Evalue=8e-37,
Organism=Escherichia coli, GI1786911, Length=229, Percent_Identity=37.5545851528384, Blast_Score=144, Evalue=5e-36,
Organism=Escherichia coli, GI1789402, Length=221, Percent_Identity=37.10407239819, Blast_Score=140, Evalue=7e-35,
Organism=Escherichia coli, GI1787375, Length=225, Percent_Identity=37.7777777777778, Blast_Score=137, Evalue=5e-34,
Organism=Escherichia coli, GI1790863, Length=231, Percent_Identity=38.961038961039, Blast_Score=137, Evalue=8e-34,
Organism=Escherichia coli, GI1790552, Length=225, Percent_Identity=36.8888888888889, Blast_Score=136, Evalue=1e-33,
Organism=Escherichia coli, GI1787229, Length=224, Percent_Identity=35.7142857142857, Blast_Score=134, Evalue=5e-33,
Organism=Escherichia coli, GI145693140, Length=244, Percent_Identity=29.9180327868852, Blast_Score=100, Evalue=6e-23,
Organism=Escherichia coli, GI1788550, Length=111, Percent_Identity=29.7297297297297, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1788191, Length=121, Percent_Identity=27.2727272727273, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1790299, Length=130, Percent_Identity=26.9230769230769, Blast_Score=62, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26070; Mature: 26070

Theoretical pI: Translated: 5.52; Mature: 5.52

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKILVIDDEENIRELIKFNLETAGYRVELAADGEEGWDRLNDSIDLIILDLMLPRIDGL
CCEEEEECCHHHHHHHHHHCCCCCCEEEEEEECCHHHHHHHCCCHHHHHHHHHHCCCCHH
SFCRQVRSNNRFKDIPIIMLTAKGEEVDKIIGLEMGADDYITKPFSPRELVARIKAVLRR
HHHHHHHCCCCCCCCCEEEEEECCCHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
VQKNEEKSDNELIKKADFELDVSSHEARKGGEVLNLTPKEFDLLRHLLVNSGKVLTRDIL
HHHCCCCCHHHHHHHCCCEEECCCCHHHCCCCEEEECHHHHHHHHHHHHCCCCHHHHHHH
LEKVWGYEYAGDTRTVDVHIRRLRRKIGDNYIVTVRGVGYKFVKLE
HHHHCCCEECCCCEEHHHHHHHHHHHHCCCEEEEEECCCEEEEEEC
>Mature Secondary Structure
MEKILVIDDEENIRELIKFNLETAGYRVELAADGEEGWDRLNDSIDLIILDLMLPRIDGL
CCEEEEECCHHHHHHHHHHCCCCCCEEEEEEECCHHHHHHHCCCHHHHHHHHHHCCCCHH
SFCRQVRSNNRFKDIPIIMLTAKGEEVDKIIGLEMGADDYITKPFSPRELVARIKAVLRR
HHHHHHHCCCCCCCCCEEEEEECCCHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
VQKNEEKSDNELIKKADFELDVSSHEARKGGEVLNLTPKEFDLLRHLLVNSGKVLTRDIL
HHHCCCCCHHHHHHHCCCEEECCCCHHHCCCCEEEECHHHHHHHHHHHHCCCCHHHHHHH
LEKVWGYEYAGDTRTVDVHIRRLRRKIGDNYIVTVRGVGYKFVKLE
HHHHCCCEECCCCEEHHHHHHHHHHHHCCCEEEEEECCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1454550; 3036763; 9387221; 9384377; 8045898; 3142862 [H]