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The map label for this gene is mcpB [H]

Identifier: 220932991

GI number: 220932991

Start: 2349741

End: 2351243

Strand: Reverse

Name: mcpB [H]

Synonym: Hore_21590

Alternate gene names: 220932991

Gene position: 2351243-2349741 (Counterclockwise)

Preceding gene: 220932992

Following gene: 220932990

Centisome position: 91.2

GC content: 36.46

Gene sequence:

>1503_bases
GTGGCTGTTCCTGTTTTTGATTATAGTGATCAGTATACTGGGGTAATCTGTGCTGATATATCCATTGAATATTTAAAAGA
TATTATTAAATGGAAACTGGGAGAAACCGGTTATGTTTATATGATTGATAAGAATGGCAACATTATAGCACATCCCGAAC
ATGATGACAACAATAAAAAGATAAATATGGGTAAATATTTTAATATTAACCATATTTATGAATCAAAGAAGGGAGATTTC
AATTATTCAGTTGATAATGAAAAATTACTGGTTTCCTATGTAACCCTTGATAAGGTTGGAGCATTGCTGGCCCAGATTCC
TGAAAAAGAAGCCTATATAGTTCAGGATTTGATTAAAAATAAAATAATTAAAGTAGGAATTTCTATACTAGTTGTGGTTA
TGGTCACCATATTTATACTGGTTAGTTTTTATTTAATCAGGCCGGTTTTAAAAATAAAAGATGAAATGCAAAAGGTATCC
CGGGGCAACCTGAATGTTGAATTAACAATTAATCATAAAGATGAGCTGGGGATTCTGGCCGGGGCCTTTAAAAAGATGGT
TGGCCAGATGAGACATATCATACAAAGTATTGATGATACTGCCAGGCAGGTTGAGAGTGCTTCCCAAGATATGAAAGAAT
CATCTAATATGATCAGTCAGGTTTCTGAACAGGTGGCTTCTTCTATTCAGGAAGTATCAAGTGGAGCCTATGAGCAGGCC
AATAATGTTGAAGAAGTTGAAGAAAAAATAAAAAATCTCTCAGAGCAAATGGAAGAACTAGCTACTACAAATAAACTGGT
GGAAGATTTATCATCTGAAATGGATATTGCCAGCATTCAGGGACAGGAAGAAATGACTAAAGTAAAAGAACAAATGGTTA
ATATTAATGATTCAATCAGTGAAGTAGCTATAAAAATAAAAAACCTGGAGCAGATATCCAGTGAAATAGATTCTATTCTT
GAAATTATTAATGGAATTGCTGAACAGACCAACCTGCTGGCATTAAATGCAGCCATAGAAGCAGCCCGGGCTGGTGAGAC
CGGGAGGGGATTCAGTGTTGTTGCTGAAGAGATCAGGGAATTATCCGAAGAGTCAGCCCGTTCTTCGAGTAAAATAAGGA
AATTAATTACCGATATCCACCGGGAAACCGATGAAGTCTCCCGGAAGATGAAAGAAGGGACCCGGCAGATAAAATATGGA
GAAGAAGTTGTCCAGTCAGCCAACCAGGCCTTTATTAGAATTAGAGAATCAATTGAGGAAGTTACAGGAGGTATCAAACA
TTCCAGTACAAATGTCCAGACAGCAAAGGTCCAGAGTGAAGAGATTAGTAGACATATTAAAAGGATAGCGGATATTTCGG
AAGAATTTTCTGCCAGTGCAGAAGAAGTTGCTGCTGCCAGTGAAGAGCAAACAGGCTCAATTGAGGAAATAAACAACAGA
TCAAGGAAATTGTTTCAAATGACCGAGGAATTAAATAAACTTATCAGGAATTTTCAAATTTAA

Upstream 100 bases:

>100_bases
ATTTAAAAACCTGGAGTGATATAAAGAAATAAAAAATTCCAGGAAAGCAACCTGGCTTTCTTTACATAAAAAAATAACTG
GAAAAGGATATGCAATTACG

Downstream 100 bases:

>100_bases
AAATAGATAATAGTAATAAAAAATTGTCCTCTTAATATATTTGCTCTGGTTTACTTTTTGTTAACATTATTTTAACAAAG
ATGTAACAATAAATTAACTA

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: H3 [H]

Number of amino acids: Translated: 500; Mature: 499

Protein sequence:

>500_residues
MAVPVFDYSDQYTGVICADISIEYLKDIIKWKLGETGYVYMIDKNGNIIAHPEHDDNNKKINMGKYFNINHIYESKKGDF
NYSVDNEKLLVSYVTLDKVGALLAQIPEKEAYIVQDLIKNKIIKVGISILVVVMVTIFILVSFYLIRPVLKIKDEMQKVS
RGNLNVELTINHKDELGILAGAFKKMVGQMRHIIQSIDDTARQVESASQDMKESSNMISQVSEQVASSIQEVSSGAYEQA
NNVEEVEEKIKNLSEQMEELATTNKLVEDLSSEMDIASIQGQEEMTKVKEQMVNINDSISEVAIKIKNLEQISSEIDSIL
EIINGIAEQTNLLALNAAIEAARAGETGRGFSVVAEEIRELSEESARSSSKIRKLITDIHRETDEVSRKMKEGTRQIKYG
EEVVQSANQAFIRIRESIEEVTGGIKHSSTNVQTAKVQSEEISRHIKRIADISEEFSASAEEVAAASEEQTGSIEEINNR
SRKLFQMTEELNKLIRNFQI

Sequences:

>Translated_500_residues
MAVPVFDYSDQYTGVICADISIEYLKDIIKWKLGETGYVYMIDKNGNIIAHPEHDDNNKKINMGKYFNINHIYESKKGDF
NYSVDNEKLLVSYVTLDKVGALLAQIPEKEAYIVQDLIKNKIIKVGISILVVVMVTIFILVSFYLIRPVLKIKDEMQKVS
RGNLNVELTINHKDELGILAGAFKKMVGQMRHIIQSIDDTARQVESASQDMKESSNMISQVSEQVASSIQEVSSGAYEQA
NNVEEVEEKIKNLSEQMEELATTNKLVEDLSSEMDIASIQGQEEMTKVKEQMVNINDSISEVAIKIKNLEQISSEIDSIL
EIINGIAEQTNLLALNAAIEAARAGETGRGFSVVAEEIRELSEESARSSSKIRKLITDIHRETDEVSRKMKEGTRQIKYG
EEVVQSANQAFIRIRESIEEVTGGIKHSSTNVQTAKVQSEEISRHIKRIADISEEFSASAEEVAAASEEQTGSIEEINNR
SRKLFQMTEELNKLIRNFQI
>Mature_499_residues
AVPVFDYSDQYTGVICADISIEYLKDIIKWKLGETGYVYMIDKNGNIIAHPEHDDNNKKINMGKYFNINHIYESKKGDFN
YSVDNEKLLVSYVTLDKVGALLAQIPEKEAYIVQDLIKNKIIKVGISILVVVMVTIFILVSFYLIRPVLKIKDEMQKVSR
GNLNVELTINHKDELGILAGAFKKMVGQMRHIIQSIDDTARQVESASQDMKESSNMISQVSEQVASSIQEVSSGAYEQAN
NVEEVEEKIKNLSEQMEELATTNKLVEDLSSEMDIASIQGQEEMTKVKEQMVNINDSISEVAIKIKNLEQISSEIDSILE
IINGIAEQTNLLALNAAIEAARAGETGRGFSVVAEEIRELSEESARSSSKIRKLITDIHRETDEVSRKMKEGTRQIKYGE
EVVQSANQAFIRIRESIEEVTGGIKHSSTNVQTAKVQSEEISRHIKRIADISEEFSASAEEVAAASEEQTGSIEEINNRS
RKLFQMTEELNKLIRNFQI

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1789453, Length=287, Percent_Identity=29.2682926829268, Blast_Score=116, Evalue=3e-27,
Organism=Escherichia coli, GI2367378, Length=301, Percent_Identity=26.578073089701, Blast_Score=112, Evalue=7e-26,
Organism=Escherichia coli, GI1788195, Length=278, Percent_Identity=31.294964028777, Blast_Score=110, Evalue=3e-25,
Organism=Escherichia coli, GI1787690, Length=373, Percent_Identity=27.8820375335121, Blast_Score=105, Evalue=8e-24,
Organism=Escherichia coli, GI1788194, Length=370, Percent_Identity=23.7837837837838, Blast_Score=98, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004010
- InterPro:   IPR003122
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR022094 [H]

Pfam domain/function: PF02743 Cache_1; PF00672 HAMP; PF12332 McpA_N; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 56181; Mature: 56050

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVPVFDYSDQYTGVICADISIEYLKDIIKWKLGETGYVYMIDKNGNIIAHPEHDDNNKK
CCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHCCCCCEEEEEECCCCEEECCCCCCCCCE
INMGKYFNINHIYESKKGDFNYSVDNEKLLVSYVTLDKVGALLAQIPEKEAYIVQDLIKN
EECCCEECHHHHHHCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
KIIKVGISILVVVMVTIFILVSFYLIRPVLKIKDEMQKVSRGNLNVELTINHKDELGILA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHH
GAFKKMVGQMRHIIQSIDDTARQVESASQDMKESSNMISQVSEQVASSIQEVSSGAYEQA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHC
NNVEEVEEKIKNLSEQMEELATTNKLVEDLSSEMDIASIQGQEEMTKVKEQMVNINDSIS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHCCCCHHH
EVAIKIKNLEQISSEIDSILEIINGIAEQTNLLALNAAIEAARAGETGRGFSVVAEEIRE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
LSEESARSSSKIRKLITDIHRETDEVSRKMKEGTRQIKYGEEVVQSANQAFIRIRESIEE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VTGGIKHSSTNVQTAKVQSEEISRHIKRIADISEEFSASAEEVAAASEEQTGSIEEINNR
HHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCHHHHHHH
SRKLFQMTEELNKLIRNFQI
HHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AVPVFDYSDQYTGVICADISIEYLKDIIKWKLGETGYVYMIDKNGNIIAHPEHDDNNKK
CCCCCCCCCCCCEEEEECCCHHHHHHHHHHHCCCCCEEEEEECCCCEEECCCCCCCCCE
INMGKYFNINHIYESKKGDFNYSVDNEKLLVSYVTLDKVGALLAQIPEKEAYIVQDLIKN
EECCCEECHHHHHHCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
KIIKVGISILVVVMVTIFILVSFYLIRPVLKIKDEMQKVSRGNLNVELTINHKDELGILA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHH
GAFKKMVGQMRHIIQSIDDTARQVESASQDMKESSNMISQVSEQVASSIQEVSSGAYEQA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHC
NNVEEVEEKIKNLSEQMEELATTNKLVEDLSSEMDIASIQGQEEMTKVKEQMVNINDSIS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHCCCCHHH
EVAIKIKNLEQISSEIDSILEIINGIAEQTNLLALNAAIEAARAGETGRGFSVVAEEIRE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
LSEESARSSSKIRKLITDIHRETDEVSRKMKEGTRQIKYGEEVVQSANQAFIRIRESIEE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VTGGIKHSSTNVQTAKVQSEEISRHIKRIADISEEFSASAEEVAAASEEQTGSIEEINNR
HHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCHHHHHHH
SRKLFQMTEELNKLIRNFQI
HHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8188684; 9384377 [H]