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The map label for this gene is yfkE [H]

Identifier: 220932971

GI number: 220932971

Start: 2327556

End: 2328605

Strand: Reverse

Name: yfkE [H]

Synonym: Hore_21390

Alternate gene names: 220932971

Gene position: 2328605-2327556 (Counterclockwise)

Preceding gene: 220932972

Following gene: 220932969

Centisome position: 90.32

GC content: 38.67

Gene sequence:

>1050_bases
ATGAAGATATTTAAATATTTGCTTATTTTTGTACCCGTCAGCTGGGGTACTTATTTTTTAAGGGGTAATTCCCTGGGTAC
ATTTATAACTTCAGCGCTGGCCATTGTTCCCCTGGCATTTATTATATCCAGGAAGACGGACAGGCTAAGGTCATATCTGG
GGAGTAGCTGGGGAGGGTTAATAAATGTAACCTTTGGTAATGCCACCGAATTAATAATATCCCTTTATGCCATAATTGAC
AGGTTGTTAAATGTAGTCAAGGCCAATATAACGGGATCTATTGTCATGAATCTCCTGCTTGTTTTAGGACTAAGCTTTTT
TACCGGCGGTCTGAAACATAGAAAACAGACCTTTGACAAAGTCCTGGCCATAGCCAATGGCACAATGCTTATGCTGGCCG
TTATTGGAATGCTAATCCCTGCTATTTTTTATTTTGCTTCTCCGAATATAAAGACCCTTGTTCTTGGAAAGTTAAGTTTA
GGGGTGGGGGCAGTACTTTTTGTTACCTATATGGCCAGTCTTTACTATACCCTGGTAATTCATGAAAATGAAAAAAAGGA
ATCCCACCGACAAATAAAAAAAAGCCCGGGACGGGGTAGTGTTATGCGTGAGGCCTTTATTCTTTTTCTGGTGACCAGTT
TAGTGGCTGTAGAAGCTAACATCCTGGTAGGTTCTATTACTATTATCCAGAAAAAGTTTAATATTTCTCCTGTCTTTATC
GGGGTTATAATACTTCCCATTATTTCCAATGTGGCTGAAAACCTCACTGCCATTACCATGGCCCGGGAGAACAAAATAGA
CCTTAGTATAAATATTGCTATTGGTTCAAGTATTCAGGTAGCCTTATTCTTGGTCCCCTTATTAATTTTTATAAGTCACC
TGATAAACCATCCCATGAATGTATTATTCAATCTTCTGGAGGTTAGTTCTATTGGTTTATCAGTTCTGGCTATAAATATT
GTTTATCTCCAGGGTGAGTCGAACTGGTTTGAAGGATTACAGTTATGTGCAGCTTACCTTATAATTGCCATTGCTTTTTA
TTTCGCCTAA

Upstream 100 bases:

>100_bases
AGGTGATTTATACCTGGAATAAAGGGTTGTGTTTTTTTATTTATTTCATATTAATTAAATGTTTTTTAGGAATAATAGAT
AATTGAGGTGGTTTATATAC

Downstream 100 bases:

>100_bases
ATGTGGTTACCTGACCGGTATTTTTAGTTTTTGACCCGGGTAAATAAGGTTATTGTTCAGGTTGTTATACTTTTTAAGTC
TATCAACAGTAACATTATAC

Product: calcium/proton antiporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 349; Mature: 349

Protein sequence:

>349_residues
MKIFKYLLIFVPVSWGTYFLRGNSLGTFITSALAIVPLAFIISRKTDRLRSYLGSSWGGLINVTFGNATELIISLYAIID
RLLNVVKANITGSIVMNLLLVLGLSFFTGGLKHRKQTFDKVLAIANGTMLMLAVIGMLIPAIFYFASPNIKTLVLGKLSL
GVGAVLFVTYMASLYYTLVIHENEKKESHRQIKKSPGRGSVMREAFILFLVTSLVAVEANILVGSITIIQKKFNISPVFI
GVIILPIISNVAENLTAITMARENKIDLSINIAIGSSIQVALFLVPLLIFISHLINHPMNVLFNLLEVSSIGLSVLAINI
VYLQGESNWFEGLQLCAAYLIIAIAFYFA

Sequences:

>Translated_349_residues
MKIFKYLLIFVPVSWGTYFLRGNSLGTFITSALAIVPLAFIISRKTDRLRSYLGSSWGGLINVTFGNATELIISLYAIID
RLLNVVKANITGSIVMNLLLVLGLSFFTGGLKHRKQTFDKVLAIANGTMLMLAVIGMLIPAIFYFASPNIKTLVLGKLSL
GVGAVLFVTYMASLYYTLVIHENEKKESHRQIKKSPGRGSVMREAFILFLVTSLVAVEANILVGSITIIQKKFNISPVFI
GVIILPIISNVAENLTAITMARENKIDLSINIAIGSSIQVALFLVPLLIFISHLINHPMNVLFNLLEVSSIGLSVLAINI
VYLQGESNWFEGLQLCAAYLIIAIAFYFA
>Mature_349_residues
MKIFKYLLIFVPVSWGTYFLRGNSLGTFITSALAIVPLAFIISRKTDRLRSYLGSSWGGLINVTFGNATELIISLYAIID
RLLNVVKANITGSIVMNLLLVLGLSFFTGGLKHRKQTFDKVLAIANGTMLMLAVIGMLIPAIFYFASPNIKTLVLGKLSL
GVGAVLFVTYMASLYYTLVIHENEKKESHRQIKKSPGRGSVMREAFILFLVTSLVAVEANILVGSITIIQKKFNISPVFI
GVIILPIISNVAENLTAITMARENKIDLSINIAIGSSIQVALFLVPLLIFISHLINHPMNVLFNLLEVSSIGLSVLAINI
VYLQGESNWFEGLQLCAAYLIIAIAFYFA

Specific function: Unknown

COG id: COG0387

COG function: function code P; Ca2+/H+ antiporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium/potassium/calcium exchanger family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6320075, Length=359, Percent_Identity=37.0473537604457, Blast_Score=203, Evalue=3e-53,
Organism=Saccharomyces cerevisiae, GI6324008, Length=396, Percent_Identity=25.5050505050505, Blast_Score=112, Evalue=8e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004713
- InterPro:   IPR004798
- InterPro:   IPR004837 [H]

Pfam domain/function: PF01699 Na_Ca_ex [H]

EC number: NA

Molecular weight: Translated: 38295; Mature: 38295

Theoretical pI: Translated: 10.17; Mature: 10.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIFKYLLIFVPVSWGTYFLRGNSLGTFITSALAIVPLAFIISRKTDRLRSYLGSSWGGL
CHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCE
INVTFGNATELIISLYAIIDRLLNVVKANITGSIVMNLLLVLGLSFFTGGLKHRKQTFDK
EEEEECCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHH
VLAIANGTMLMLAVIGMLIPAIFYFASPNIKTLVLGKLSLGVGAVLFVTYMASLYYTLVI
HHHHHCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHEEEEE
HENEKKESHRQIKKSPGRGSVMREAFILFLVTSLVAVEANILVGSITIIQKKFNISPVFI
ECCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEHHEEEEHHCCCCHHHH
GVIILPIISNVAENLTAITMARENKIDLSINIAIGSSIQVALFLVPLLIFISHLINHPMN
HHHHHHHHHHHHHHHHHHEEEECCCEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHCHHH
VLFNLLEVSSIGLSVLAINIVYLQGESNWFEGLQLCAAYLIIAIAFYFA
HHHHHHHHHHHCCEEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MKIFKYLLIFVPVSWGTYFLRGNSLGTFITSALAIVPLAFIISRKTDRLRSYLGSSWGGL
CHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCE
INVTFGNATELIISLYAIIDRLLNVVKANITGSIVMNLLLVLGLSFFTGGLKHRKQTFDK
EEEEECCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHH
VLAIANGTMLMLAVIGMLIPAIFYFASPNIKTLVLGKLSLGVGAVLFVTYMASLYYTLVI
HHHHHCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHEEEEE
HENEKKESHRQIKKSPGRGSVMREAFILFLVTSLVAVEANILVGSITIIQKKFNISPVFI
ECCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEHHEEEEHHCCCCHHHH
GVIILPIISNVAENLTAITMARENKIDLSINIAIGSSIQVALFLVPLLIFISHLINHPMN
HHHHHHHHHHHHHHHHHHEEEECCCEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHCHHH
VLFNLLEVSSIGLSVLAINIVYLQGESNWFEGLQLCAAYLIIAIAFYFA
HHHHHHHHHHHCCEEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8969503; 9384377 [H]