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The map label for this gene is ycgM [C]

Identifier: 220932929

GI number: 220932929

Start: 2272540

End: 2273340

Strand: Reverse

Name: ycgM [C]

Synonym: Hore_20970

Alternate gene names: 220932929

Gene position: 2273340-2272540 (Counterclockwise)

Preceding gene: 220932930

Following gene: 220932926

Centisome position: 88.18

GC content: 38.83

Gene sequence:

>801_bases
ATGCATTATAATTATAGGTATGGAGGTGGGAAGAAAATTAAATTTGTAAGGTTTTTATTTAAAGGGGAAAAATATTATGG
ATTGCTAAAAAAGGACAGGGTAATTCCCATCAAAGGGGATCCATTCTCTGGCTGGGAAGAGGATGGTAGTAAGACATATT
CAGTTGCTGATGTAAAATTTTTGGCTCCGTGTCAGCCGTCAAAAATTATTGCTGTTGGTTTAAATTATTATGACCATGCC
CGGGAATTAAATATGGAGATACCTGAAGAGCCTGTTATTTTTTTAAAACCCCCTACATCAGTAATAGGTCCTGAGGATTA
TATTATATTACCTGAACAGAGTGGAAGGGTTGATTATGAAGCCGAACTGGCTGTTGTTATCCAGAAAGAGGCCAGAAATG
TTTCACATGAAATAGCAAAAGATGTAATTCTGGGGTATACGTGTGGCAATGATATTACGGCCAGGGACCTCCAGAAAAAG
GATGGACAATGGACAAGGGCAAAATCTTTTGATACATTTTTACCTTTAGGTCCTGTGATTTCAGATGAATTTAAACCCGG
TAGTGGTAGGATAGAATTAAAGGTGGATGGGGAAGTGAAACAGGGTTCAAATACTGACCAGATGATTTTTGATGTCTATG
ACCTGGTTGTTTTTATTTCCGGGATAATGACCTTGAAACCAGGGGATGTTATCATCACCGGGACTCCGGGGGGGATTGGC
CCTCTAAAAGAGAATAGTAAAGTGGAGGTTTATATAGAAGGTATCGGTAACCTGGTTAATTATACAAAAAGGGGCGATTA
A

Upstream 100 bases:

>100_bases
GGCTTTTTTTACCTTCTGGATAATTATGGCCGGGGACCGCTTTGTTCATAATTTACATCCCAAAAAGGATATAAATAAAA
ACAGGAGAAATAAATAGATA

Downstream 100 bases:

>100_bases
AAATCGCCCCTGCTTTTATGGAGGTTGTATTTTTGGTTATTAAGCTTTAAAAAAGTAAATTCAGGGTGTTTATACCTTAA
ATTTTTCCCTTTATAGCAGG

Product: 5-carboxymethyl-2-hydroxymuconate Delta-isomerase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 266; Mature: 266

Protein sequence:

>266_residues
MHYNYRYGGGKKIKFVRFLFKGEKYYGLLKKDRVIPIKGDPFSGWEEDGSKTYSVADVKFLAPCQPSKIIAVGLNYYDHA
RELNMEIPEEPVIFLKPPTSVIGPEDYIILPEQSGRVDYEAELAVVIQKEARNVSHEIAKDVILGYTCGNDITARDLQKK
DGQWTRAKSFDTFLPLGPVISDEFKPGSGRIELKVDGEVKQGSNTDQMIFDVYDLVVFISGIMTLKPGDVIITGTPGGIG
PLKENSKVEVYIEGIGNLVNYTKRGD

Sequences:

>Translated_266_residues
MHYNYRYGGGKKIKFVRFLFKGEKYYGLLKKDRVIPIKGDPFSGWEEDGSKTYSVADVKFLAPCQPSKIIAVGLNYYDHA
RELNMEIPEEPVIFLKPPTSVIGPEDYIILPEQSGRVDYEAELAVVIQKEARNVSHEIAKDVILGYTCGNDITARDLQKK
DGQWTRAKSFDTFLPLGPVISDEFKPGSGRIELKVDGEVKQGSNTDQMIFDVYDLVVFISGIMTLKPGDVIITGTPGGIG
PLKENSKVEVYIEGIGNLVNYTKRGD
>Mature_266_residues
MHYNYRYGGGKKIKFVRFLFKGEKYYGLLKKDRVIPIKGDPFSGWEEDGSKTYSVADVKFLAPCQPSKIIAVGLNYYDHA
RELNMEIPEEPVIFLKPPTSVIGPEDYIILPEQSGRVDYEAELAVVIQKEARNVSHEIAKDVILGYTCGNDITARDLQKK
DGQWTRAKSFDTFLPLGPVISDEFKPGSGRIELKVDGEVKQGSNTDQMIFDVYDLVVFISGIMTLKPGDVIITGTPGGIG
PLKENSKVEVYIEGIGNLVNYTKRGD

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI40786394, Length=241, Percent_Identity=41.49377593361, Blast_Score=181, Evalue=7e-46,
Organism=Homo sapiens, GI156231349, Length=241, Percent_Identity=41.0788381742739, Blast_Score=179, Evalue=2e-45,
Organism=Homo sapiens, GI215422413, Length=200, Percent_Identity=39.5, Blast_Score=145, Evalue=3e-35,
Organism=Homo sapiens, GI66348062, Length=193, Percent_Identity=40.4145077720207, Blast_Score=145, Evalue=4e-35,
Organism=Homo sapiens, GI13654274, Length=197, Percent_Identity=39.5939086294416, Blast_Score=145, Evalue=4e-35,
Organism=Escherichia coli, GI1787428, Length=195, Percent_Identity=39.4871794871795, Blast_Score=141, Evalue=4e-35,
Organism=Caenorhabditis elegans, GI17557057, Length=189, Percent_Identity=40.2116402116402, Blast_Score=124, Evalue=4e-29,
Organism=Saccharomyces cerevisiae, GI6324161, Length=221, Percent_Identity=32.579185520362, Blast_Score=117, Evalue=2e-27,
Organism=Drosophila melanogaster, GI28572127, Length=286, Percent_Identity=37.4125874125874, Blast_Score=157, Evalue=8e-39,
Organism=Drosophila melanogaster, GI24663695, Length=215, Percent_Identity=36.7441860465116, Blast_Score=123, Evalue=2e-28,
Organism=Drosophila melanogaster, GI28571789, Length=201, Percent_Identity=35.8208955223881, Blast_Score=117, Evalue=1e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: NA

Molecular weight: Translated: 29678; Mature: 29678

Theoretical pI: Translated: 5.48; Mature: 5.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHYNYRYGGGKKIKFVRFLFKGEKYYGLLKKDRVIPIKGDPFSGWEEDGSKTYSVADVKF
CCCEEEECCCCEEEEEEEEECCCCEEEECCCCCEEEECCCCCCCCCCCCCEEEEEEEEEE
LAPCQPSKIIAVGLNYYDHARELNMEIPEEPVIFLKPPTSVIGPEDYIILPEQSGRVDYE
ECCCCCCEEEEEECCCHHHHHHCCCCCCCCCEEEECCCCCCCCCCCEEEEECCCCCCCEE
AELAVVIQKEARNVSHEIAKDVILGYTCGNDITARDLQKKDGQWTRAKSFDTFLPLGPVI
EEEEEEEEHHHHHHHHHHHHHEEEEEECCCCCCHHHHHHCCCCEEECCCCCCCCCCCCCC
SDEFKPGSGRIELKVDGEVKQGSNTDQMIFDVYDLVVFISGIMTLKPGDVIITGTPGGIG
CCCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHEEECCCCEEEECCCCCCC
PLKENSKVEVYIEGIGNLVNYTKRGD
CCCCCCEEEEEEEECCHHHHHCCCCC
>Mature Secondary Structure
MHYNYRYGGGKKIKFVRFLFKGEKYYGLLKKDRVIPIKGDPFSGWEEDGSKTYSVADVKF
CCCEEEECCCCEEEEEEEEECCCCEEEECCCCCEEEECCCCCCCCCCCCCEEEEEEEEEE
LAPCQPSKIIAVGLNYYDHARELNMEIPEEPVIFLKPPTSVIGPEDYIILPEQSGRVDYE
ECCCCCCEEEEEECCCHHHHHHCCCCCCCCCEEEECCCCCCCCCCCEEEEECCCCCCCEE
AELAVVIQKEARNVSHEIAKDVILGYTCGNDITARDLQKKDGQWTRAKSFDTFLPLGPVI
EEEEEEEEHHHHHHHHHHHHHEEEEEECCCCCCHHHHHHCCCCEEECCCCCCCCCCCCCC
SDEFKPGSGRIELKVDGEVKQGSNTDQMIFDVYDLVVFISGIMTLKPGDVIITGTPGGIG
CCCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHEEECCCCEEEECCCCCCC
PLKENSKVEVYIEGIGNLVNYTKRGD
CCCCCCEEEEEEEECCHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]