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The map label for this gene is xylR [H]

Identifier: 220932901

GI number: 220932901

Start: 2238347

End: 2239498

Strand: Reverse

Name: xylR [H]

Synonym: Hore_20690

Alternate gene names: 220932901

Gene position: 2239498-2238347 (Counterclockwise)

Preceding gene: 220932903

Following gene: 220932900

Centisome position: 86.86

GC content: 40.1

Gene sequence:

>1152_bases
ATGAAAAAAATAAACCAGCAGACAATTTTAGAATTAATAAATAATAAAGGGCCTATTTCCAGGGCTGAAATAGCTGAGAT
TACTGGATTAACGCCGGCTACTGTCTCCAACATAGTAAAGGATCTCCTTAAGATGGATCTGGTCAGAGAAACCCGGCAGG
GAGAATCCCGGGGAGGAAGAAAACCCATCTTACTGGAGGTAAATCCAGAAGGAGCCTACGTAATCGGCCTTGAATGGGGA
ATAGGGGAAATAAAGGCTGTTCTACTTAATTTAAATAAGAAGGTAATTAAAACTATAAAAAAACAGGTAGATAGTTTTAA
ACCTGAGTGGTTTTTAAAGACTACAGTAACAATATTTGAAGAGGTTACTGGTTATGTAGAAAATCCAGATAAGGTATTTG
GTCTCGGGATAGGGATTCATGGTTTAGTTGATCCAGATGAAGGTGTTTCCCTGTATGCCCCCCATTTTGGCTGGGAGAAT
ATTAAAATAGGTAAATTATTAAAACAGGAATTACAGATTCCTATTATGCTGGATAATGATGTCAGGATGATGGCCCTGGC
TGAAAAATGGGAAGGCAGGGATAATTTTATATTTATTAACACCGGGCCAGGGATAGGTTCAGCTATAGTTATTAAAGGAG
AACTCCTCTATGGTAGAGATTTCGGAGCCGGGGAATTCGGCCATATGACTATTGTTGAAGATGGGGCCCTCTGTAGTTGT
GGTAATCGCGGTTGTATTGAAGCCCTGGTTTCTGTTAATAACCTTGTCAGGGAATATAATGATTCACTACCGGAACATAT
ATCATTCCATGATATAAAGCGGGAGTGGAATCTTTTAATAGATTTAGCCCGTGAAGAAAAATCCAGGGCCTATTCTATAA
TTGAAAAGGCGGGCGTGTATCTAGGTAAGGGAATAGGAAATGTGGTTAATCTTTTAAACCCGGAAGCGGTAGTAATCGGA
GGAGACTTTTTACTGGCCAGGGATTTGATTTTTCCGGTTATTAAAGAACAGGTATTAGAGACTGCCCTTAAGGTTCCGTC
AAGGGACCTTGAAATAACAGGGACTGCTTTTGGTGAGAAGGTTGGTGCTATCGGGGCCGGTACCAGAGTCCTGCAGGAAA
TTTTTAAATTAAAAAAGGAGGAAGATAAATGA

Upstream 100 bases:

>100_bases
GGAAGTGTTATAATAAACTTAGTTAATTAATTAAATAAACGAAGTTAACAAAACCAGAGTGAAAGGGGGAATTAAACTGA
AGAGGGGAAGCTTTAAATTA

Downstream 100 bases:

>100_bases
ATATACTGGTGACAGGAGGAGCCGGTTATATTGGGAGTCATGTAGTGAAAAGCCTGTTTGAGGCTGGTTATAATGTTGTT
ACCCTGGATAATCTTGAGAA

Product: ROK family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 383; Mature: 383

Protein sequence:

>383_residues
MKKINQQTILELINNKGPISRAEIAEITGLTPATVSNIVKDLLKMDLVRETRQGESRGGRKPILLEVNPEGAYVIGLEWG
IGEIKAVLLNLNKKVIKTIKKQVDSFKPEWFLKTTVTIFEEVTGYVENPDKVFGLGIGIHGLVDPDEGVSLYAPHFGWEN
IKIGKLLKQELQIPIMLDNDVRMMALAEKWEGRDNFIFINTGPGIGSAIVIKGELLYGRDFGAGEFGHMTIVEDGALCSC
GNRGCIEALVSVNNLVREYNDSLPEHISFHDIKREWNLLIDLAREEKSRAYSIIEKAGVYLGKGIGNVVNLLNPEAVVIG
GDFLLARDLIFPVIKEQVLETALKVPSRDLEITGTAFGEKVGAIGAGTRVLQEIFKLKKEEDK

Sequences:

>Translated_383_residues
MKKINQQTILELINNKGPISRAEIAEITGLTPATVSNIVKDLLKMDLVRETRQGESRGGRKPILLEVNPEGAYVIGLEWG
IGEIKAVLLNLNKKVIKTIKKQVDSFKPEWFLKTTVTIFEEVTGYVENPDKVFGLGIGIHGLVDPDEGVSLYAPHFGWEN
IKIGKLLKQELQIPIMLDNDVRMMALAEKWEGRDNFIFINTGPGIGSAIVIKGELLYGRDFGAGEFGHMTIVEDGALCSC
GNRGCIEALVSVNNLVREYNDSLPEHISFHDIKREWNLLIDLAREEKSRAYSIIEKAGVYLGKGIGNVVNLLNPEAVVIG
GDFLLARDLIFPVIKEQVLETALKVPSRDLEITGTAFGEKVGAIGAGTRVLQEIFKLKKEEDK
>Mature_383_residues
MKKINQQTILELINNKGPISRAEIAEITGLTPATVSNIVKDLLKMDLVRETRQGESRGGRKPILLEVNPEGAYVIGLEWG
IGEIKAVLLNLNKKVIKTIKKQVDSFKPEWFLKTTVTIFEEVTGYVENPDKVFGLGIGIHGLVDPDEGVSLYAPHFGWEN
IKIGKLLKQELQIPIMLDNDVRMMALAEKWEGRDNFIFINTGPGIGSAIVIKGELLYGRDFGAGEFGHMTIVEDGALCSC
GNRGCIEALVSVNNLVREYNDSLPEHISFHDIKREWNLLIDLAREEKSRAYSIIEKAGVYLGKGIGNVVNLLNPEAVVIG
GDFLLARDLIFPVIKEQVLETALKVPSRDLEITGTAFGEKVGAIGAGTRVLQEIFKLKKEEDK

Specific function: Transcriptional repressor of xylose-utilizing enzymes [H]

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Homo sapiens, GI298566315, Length=262, Percent_Identity=31.2977099236641, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI298566325, Length=262, Percent_Identity=31.2977099236641, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI4885285, Length=262, Percent_Identity=31.2977099236641, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI190014632, Length=262, Percent_Identity=31.2977099236641, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI298566312, Length=139, Percent_Identity=33.0935251798561, Blast_Score=71, Evalue=1e-12,
Organism=Escherichia coli, GI1786891, Length=380, Percent_Identity=28.6842105263158, Blast_Score=164, Evalue=1e-41,
Organism=Escherichia coli, GI1787878, Length=385, Percent_Identity=24.9350649350649, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI87082127, Length=340, Percent_Identity=27.6470588235294, Blast_Score=125, Evalue=4e-30,
Organism=Escherichia coli, GI1787363, Length=278, Percent_Identity=26.978417266187, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI87081733, Length=223, Percent_Identity=26.457399103139, Blast_Score=69, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000600
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00480 ROK [H]

EC number: NA

Molecular weight: Translated: 42345; Mature: 42345

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKINQQTILELINNKGPISRAEIAEITGLTPATVSNIVKDLLKMDLVRETRQGESRGGR
CCCCCHHHHHHHHCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
KPILLEVNPEGAYVIGLEWGIGEIKAVLLNLNKKVIKTIKKQVDSFKPEWFLKTTVTIFE
CCEEEEECCCCCEEEEEECCHHHHHHHHHHCCHHHHHHHHHHHHCCCCCEEHHHHHHHHH
EVTGYVENPDKVFGLGIGIHGLVDPDEGVSLYAPHFGWENIKIGKLLKQELQIPIMLDND
HHHCCCCCCCEEEEEEECCCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHCCCEEEECCC
VRMMALAEKWEGRDNFIFINTGPGIGSAIVIKGELLYGRDFGAGEFGHMTIVEDGALCSC
CCEEHHHHHCCCCCCEEEEECCCCCCEEEEEEEEEEECCCCCCCCCCCEEEEECCCEECC
GNRGCIEALVSVNNLVREYNDSLPEHISFHDIKREWNLLIDLAREEKSRAYSIIEKAGVY
CCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGKGIGNVVNLLNPEAVVIGGDFLLARDLIFPVIKEQVLETALKVPSRDLEITGTAFGEK
HHCCHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECHHHHH
VGAIGAGTRVLQEIFKLKKEEDK
HCCCCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKKINQQTILELINNKGPISRAEIAEITGLTPATVSNIVKDLLKMDLVRETRQGESRGGR
CCCCCHHHHHHHHCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
KPILLEVNPEGAYVIGLEWGIGEIKAVLLNLNKKVIKTIKKQVDSFKPEWFLKTTVTIFE
CCEEEEECCCCCEEEEEECCHHHHHHHHHHCCHHHHHHHHHHHHCCCCCEEHHHHHHHHH
EVTGYVENPDKVFGLGIGIHGLVDPDEGVSLYAPHFGWENIKIGKLLKQELQIPIMLDND
HHHCCCCCCCEEEEEEECCCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHCCCEEEECCC
VRMMALAEKWEGRDNFIFINTGPGIGSAIVIKGELLYGRDFGAGEFGHMTIVEDGALCSC
CCEEHHHHHCCCCCCEEEEECCCCCCEEEEEEEEEEECCCCCCCCCCCEEEEECCCEECC
GNRGCIEALVSVNNLVREYNDSLPEHISFHDIKREWNLLIDLAREEKSRAYSIIEKAGVY
CCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGKGIGNVVNLLNPEAVVIGGDFLLARDLIFPVIKEQVLETALKVPSRDLEITGTAFGEK
HHCCHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECHHHHH
VGAIGAGTRVLQEIFKLKKEEDK
HCCCCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2544559 [H]