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The map label for this gene is galE [H]

Identifier: 220932900

GI number: 220932900

Start: 2237364

End: 2238350

Strand: Reverse

Name: galE [H]

Synonym: Hore_20680

Alternate gene names: 220932900

Gene position: 2238350-2237364 (Counterclockwise)

Preceding gene: 220932901

Following gene: 220932899

Centisome position: 86.82

GC content: 43.77

Gene sequence:

>987_bases
ATGAATATACTGGTGACAGGAGGAGCCGGTTATATTGGGAGTCATGTAGTGAAAAGCCTGTTTGAGGCTGGTTATAATGT
TGTTACCCTGGATAATCTTGAGAAGGGTCACCGGGAAGCTGTCCTGGGCGGTGAGTTTATTAAGGGTGATCTCAAGGACA
GAGAGCTGTTAGACAGCATAATGAAAGATTATGAAATAGATGGTGTCATTCATCTGGCTGCCCACAGTCTGGTAGGAGAG
TCAATGGAAAACCCGGGGAAGTATTATAAAAATAATGTTTCCAATGGCTTAAATTTACTGGAAGCTATGGTTGATAATGA
TGTGAAATACCTGGTTTTTTCTTCTACAGCTGCAGTTTATGGGGAACCCAGGGAAGTCCCCATCACAGAAGATCATCCAA
CAGCTCCGACAAATACCTATGGGGAGAGTAAACTCTTTTTTGAAAAGATGATGAAACGGTATGATGAAATTTATGGACTT
AAGTATGTATCCCTCCGTTACTTTAATGCAGCCGGGGCCGATCTATCAGGTAAAATTGGGGAAGACCATGACCCTGAGAC
CCATTTGATTCCCATTGTACTTCAGAAAGCACTGGGTTTACGGGATAAGCTATATATTTTCGGGAATGATTACCCGACCA
GGGATGGAACTTGTATCCGGGATTATATCCATGTCAATGACCTGGCTGATGCCCATGTCCTGGCTATTGAAGGTTTAACA
CGGGGTCTGGAGAGCCGTATTTATAACCTTGGTAATGGTGAAGGTTATTCTGTAAAAGAGGTAATTGAAACTGCCAGCAG
GGTTATCGGCAAACCGATTGAAGCCGGGGTTGGTGACAGGCGACCCGGGGATCCAGCTGTTCTGGTGGCAAGTTCAGATA
AAATTAAAGAGGAGCTGGGATGGGATCCACAGTATCCTGACCTGGAAACTATAATTGAAACTGCCTGGCAATGGCATAAA
AGGGGTGGTTTTAATGAAAATGAATAA

Upstream 100 bases:

>100_bases
TTGAAATAACAGGGACTGCTTTTGGTGAGAAGGTTGGTGCTATCGGGGCCGGTACCAGAGTCCTGCAGGAAATTTTTAAA
TTAAAAAAGGAGGAAGATAA

Downstream 100 bases:

>100_bases
AAAGCGGATAACCAGGGATGATGGTCGTTACTTAATTTATTATACCTTTGAGGAGGAAAAGACGGAGGCTAAAGATGGAG
ATAAAAAAGAAAAAGAAAGG

Product: UDP-glucose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 328; Mature: 328

Protein sequence:

>328_residues
MNILVTGGAGYIGSHVVKSLFEAGYNVVTLDNLEKGHREAVLGGEFIKGDLKDRELLDSIMKDYEIDGVIHLAAHSLVGE
SMENPGKYYKNNVSNGLNLLEAMVDNDVKYLVFSSTAAVYGEPREVPITEDHPTAPTNTYGESKLFFEKMMKRYDEIYGL
KYVSLRYFNAAGADLSGKIGEDHDPETHLIPIVLQKALGLRDKLYIFGNDYPTRDGTCIRDYIHVNDLADAHVLAIEGLT
RGLESRIYNLGNGEGYSVKEVIETASRVIGKPIEAGVGDRRPGDPAVLVASSDKIKEELGWDPQYPDLETIIETAWQWHK
RGGFNENE

Sequences:

>Translated_328_residues
MNILVTGGAGYIGSHVVKSLFEAGYNVVTLDNLEKGHREAVLGGEFIKGDLKDRELLDSIMKDYEIDGVIHLAAHSLVGE
SMENPGKYYKNNVSNGLNLLEAMVDNDVKYLVFSSTAAVYGEPREVPITEDHPTAPTNTYGESKLFFEKMMKRYDEIYGL
KYVSLRYFNAAGADLSGKIGEDHDPETHLIPIVLQKALGLRDKLYIFGNDYPTRDGTCIRDYIHVNDLADAHVLAIEGLT
RGLESRIYNLGNGEGYSVKEVIETASRVIGKPIEAGVGDRRPGDPAVLVASSDKIKEELGWDPQYPDLETIIETAWQWHK
RGGFNENE
>Mature_328_residues
MNILVTGGAGYIGSHVVKSLFEAGYNVVTLDNLEKGHREAVLGGEFIKGDLKDRELLDSIMKDYEIDGVIHLAAHSLVGE
SMENPGKYYKNNVSNGLNLLEAMVDNDVKYLVFSSTAAVYGEPREVPITEDHPTAPTNTYGESKLFFEKMMKRYDEIYGL
KYVSLRYFNAAGADLSGKIGEDHDPETHLIPIVLQKALGLRDKLYIFGNDYPTRDGTCIRDYIHVNDLADAHVLAIEGLT
RGLESRIYNLGNGEGYSVKEVIETASRVIGKPIEAGVGDRRPGDPAVLVASSDKIKEELGWDPQYPDLETIIETAWQWHK
RGGFNENE

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=338, Percent_Identity=44.0828402366864, Blast_Score=249, Evalue=3e-66,
Organism=Homo sapiens, GI56118217, Length=338, Percent_Identity=44.0828402366864, Blast_Score=249, Evalue=3e-66,
Organism=Homo sapiens, GI189083684, Length=338, Percent_Identity=44.0828402366864, Blast_Score=249, Evalue=3e-66,
Organism=Homo sapiens, GI42516563, Length=315, Percent_Identity=27.9365079365079, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI7657641, Length=339, Percent_Identity=27.7286135693215, Blast_Score=95, Evalue=8e-20,
Organism=Escherichia coli, GI1786974, Length=334, Percent_Identity=42.814371257485, Blast_Score=253, Evalue=1e-68,
Organism=Escherichia coli, GI48994969, Length=349, Percent_Identity=29.2263610315186, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1788353, Length=354, Percent_Identity=29.9435028248588, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1790049, Length=267, Percent_Identity=28.0898876404494, Blast_Score=81, Evalue=8e-17,
Organism=Escherichia coli, GI1788366, Length=357, Percent_Identity=23.249299719888, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1788365, Length=346, Percent_Identity=24.2774566473988, Blast_Score=65, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI71982035, Length=344, Percent_Identity=40.406976744186, Blast_Score=223, Evalue=1e-58,
Organism=Caenorhabditis elegans, GI71982038, Length=346, Percent_Identity=40.1734104046243, Blast_Score=222, Evalue=2e-58,
Organism=Caenorhabditis elegans, GI17568069, Length=339, Percent_Identity=29.4985250737463, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17539532, Length=314, Percent_Identity=27.0700636942675, Blast_Score=86, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI115532424, Length=325, Percent_Identity=26.1538461538462, Blast_Score=73, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6319493, Length=345, Percent_Identity=42.0289855072464, Blast_Score=233, Evalue=3e-62,
Organism=Drosophila melanogaster, GI19923002, Length=340, Percent_Identity=41.4705882352941, Blast_Score=254, Evalue=8e-68,
Organism=Drosophila melanogaster, GI21356223, Length=316, Percent_Identity=26.5822784810127, Blast_Score=92, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 36414; Mature: 36414

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNILVTGGAGYIGSHVVKSLFEAGYNVVTLDNLEKGHREAVLGGEFIKGDLKDRELLDSI
CEEEEECCCCHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHCCHHHCCCCCHHHHHHHH
MKDYEIDGVIHLAAHSLVGESMENPGKYYKNNVSNGLNLLEAMVDNDVKYLVFSSTAAVY
HHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHC
GEPREVPITEDHPTAPTNTYGESKLFFEKMMKRYDEIYGLKYVSLRYFNAAGADLSGKIG
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCEEEEEEEECCCCCCCCCCCC
EDHDPETHLIPIVLQKALGLRDKLYIFGNDYPTRDGTCIRDYIHVNDLADAHVLAIEGLT
CCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCEEEHEEECCCCCCHHHHHHHHHH
RGLESRIYNLGNGEGYSVKEVIETASRVIGKPIEAGVGDRRPGDPAVLVASSDKIKEELG
HHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCHHCCCCCCCCCCCEEEEECCHHHHHHCC
WDPQYPDLETIIETAWQWHKRGGFNENE
CCCCCCCHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MNILVTGGAGYIGSHVVKSLFEAGYNVVTLDNLEKGHREAVLGGEFIKGDLKDRELLDSI
CEEEEECCCCHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHCCHHHCCCCCHHHHHHHH
MKDYEIDGVIHLAAHSLVGESMENPGKYYKNNVSNGLNLLEAMVDNDVKYLVFSSTAAVY
HHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHC
GEPREVPITEDHPTAPTNTYGESKLFFEKMMKRYDEIYGLKYVSLRYFNAAGADLSGKIG
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCEEEEEEEECCCCCCCCCCCC
EDHDPETHLIPIVLQKALGLRDKLYIFGNDYPTRDGTCIRDYIHVNDLADAHVLAIEGLT
CCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCEEEHEEECCCCCCHHHHHHHHHH
RGLESRIYNLGNGEGYSVKEVIETASRVIGKPIEAGVGDRRPGDPAVLVASSDKIKEELG
HHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCHHCCCCCCCCCCCEEEEECCHHHHHHCC
WDPQYPDLETIIETAWQWHKRGGFNENE
CCCCCCCHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]