Click here to switch to the map view.

The map label for this gene is hsdS [H]

Identifier: 220932853

GI number: 220932853

Start: 2178735

End: 2180432

Strand: Reverse

Name: hsdS [H]

Synonym: Hore_20210

Alternate gene names: 220932853

Gene position: 2180432-2178735 (Counterclockwise)

Preceding gene: 220932854

Following gene: 220932852

Centisome position: 84.57

GC content: 29.8

Gene sequence:

>1698_bases
ATGAAAAAAATTATAGATAATTTTCAGTTAATCTTTGATTCCAGGGAAAAGATTCAGGAATTAAGAAATTTAATTTTAAA
TTTAGCTGTCAGAGGAAAGCTTGTGCCTCAGAACTCGGATGATGAACCATCATCAGTATTGATTGAAAAAATAAAAAAAG
AGAAAGAAAGATTAATTAAAGAAAAGAAAATTAGAAAAAAGAAACCCTTACCACCAATCAAAGAAGAAGAAATTCCTTTT
GAATTACCTGAAAGCTGGGAATGGGTGAGGTTAGGGAATATCGGAAGGATAGTTGGAGGTGGAACTCCTAAAACTAAAGT
ACATGCGTATTGGGAAAATGGTAATATTGCATGGTTAACCCCAGCAGATTTAAACGGGCTTAAATCAAAGTATATTTCTA
GGGGACGGAGAAATATTACTAAATTGGGTTTGCAAAATAGTTCAGCAAAACTTTTGCCCAAAGGAAGCGTATTGTTTTCA
AGTAGAGCTCCTATAGGGTATGTAGCAATTGCACAAAATGATTTAGCAACAAATCAAGGATTTAAATCATGTGTTCCATA
TATTATGGATATGAATCAATATATTTATTATTTTTTGATGTATGATGCCAAAAGAATAAATGATAATGCTTCAGGGACTA
CTTTTAAAGAAGTATCTGGGAAAGAGGTCGCAAATTTTATTTTCCCATTACCACCTCTTAATGAACAGAAACGTATCGTA
AACAAATTGGATGAGTTAATGACCTTTTGTGACCAACTTGAAGTATCATTAGAAAAAAAGGCTAACGCAAAACAATTAGT
ATCAAAGAGTATTTCAAATAGAATTCAAAAGAGTAAGAGTAAAGAAGAATTAGATAAGAATATAACATTTATAATTAGAA
ACCTTAAAGAAGTATATACAACACCTGAAAATTTAAATGATTTAAAAGATATCATTCTCCAGTTGGCTATTCAGGGTAAG
CTTGTGCCTCAGGATCCGGATGATGAACCAGCATCAGTATTAATTGAAAAAATAAATAAAGAAAAAGAAAGATTAATTAA
AGAAAAGAAAATTAGAAAAACCAAACCCTTACCACCAATAAAAGAAGCTGAAATTCCCTTTGAATTACCTAAAGGCTGGG
AATGGGTGAGGTTGGGAGAAATAATGATAATTAATCAACGAAATAAATTAAATGATAATTTAGAAGTGTCATTTGTTCCA
ATGAAGCTGATTGAAGATGGTTATTTAAGTAAACACAGTCATAAAAAGAAGTTATGGAAAGAAGTAAAAAAAGGTTATAC
TCATTTTAAAGAAAATGATTTGGTAGTAGCTAAGATTACTCCTTGCTTTGAAAATAGAAAATCAGCAATCATGAAAAATT
TATATTCAGGTTATGGAGCTGGGACAACTGAATTGCATGTTCTTACCAGCTACTTAAAAGAAATAGATATGAAATTTTTC
CTCTACATTGTAAAAGCAAAGAATTTTATTAATCAAGGGGTTTCAACTTTTACTGGAACAGCTGGACAGCAAAGAATTAG
AAAAGATTTTATAGAAAATTTTGTTATAGGTTTACCTCCGTTAAATGAACAGAAACAAATTGTCAAAAAAATAGACAAAT
TAATGGCCTTATGTAATTTACTAGAAAACCAAATTAATAAAAATAGAAATAATAGTGAGTTATTAATGAAATCTTTACAA
AGGAAATTATTTGAGTGA

Upstream 100 bases:

>100_bases
CCGAGGTTATTTTAAAAAAATATAATGAAGCTGTTAAAGAGGTAGAAGAAATTCAAGAAAAAATCATTGCTGAACTAAGA
AAGTTATTGTAGGTGGTAAT

Downstream 100 bases:

>100_bases
CTATATTATTAAATGCTGGACAATCAGATAATTTTTTTAATAGCTGATGAGTGTTATATATTTTAATTAACCTAATAGGT
TAATTAAAATTGACATCTGG

Product: restriction modification system DNA specificity domain-containing protein

Products: NA

Alternate protein names: S.EcoAI; Type I restriction enzyme EcoAI specificity protein; S protein [H]

Number of amino acids: Translated: 565; Mature: 565

Protein sequence:

>565_residues
MKKIIDNFQLIFDSREKIQELRNLILNLAVRGKLVPQNSDDEPSSVLIEKIKKEKERLIKEKKIRKKKPLPPIKEEEIPF
ELPESWEWVRLGNIGRIVGGGTPKTKVHAYWENGNIAWLTPADLNGLKSKYISRGRRNITKLGLQNSSAKLLPKGSVLFS
SRAPIGYVAIAQNDLATNQGFKSCVPYIMDMNQYIYYFLMYDAKRINDNASGTTFKEVSGKEVANFIFPLPPLNEQKRIV
NKLDELMTFCDQLEVSLEKKANAKQLVSKSISNRIQKSKSKEELDKNITFIIRNLKEVYTTPENLNDLKDIILQLAIQGK
LVPQDPDDEPASVLIEKINKEKERLIKEKKIRKTKPLPPIKEAEIPFELPKGWEWVRLGEIMIINQRNKLNDNLEVSFVP
MKLIEDGYLSKHSHKKKLWKEVKKGYTHFKENDLVVAKITPCFENRKSAIMKNLYSGYGAGTTELHVLTSYLKEIDMKFF
LYIVKAKNFINQGVSTFTGTAGQQRIRKDFIENFVIGLPPLNEQKQIVKKIDKLMALCNLLENQINKNRNNSELLMKSLQ
RKLFE

Sequences:

>Translated_565_residues
MKKIIDNFQLIFDSREKIQELRNLILNLAVRGKLVPQNSDDEPSSVLIEKIKKEKERLIKEKKIRKKKPLPPIKEEEIPF
ELPESWEWVRLGNIGRIVGGGTPKTKVHAYWENGNIAWLTPADLNGLKSKYISRGRRNITKLGLQNSSAKLLPKGSVLFS
SRAPIGYVAIAQNDLATNQGFKSCVPYIMDMNQYIYYFLMYDAKRINDNASGTTFKEVSGKEVANFIFPLPPLNEQKRIV
NKLDELMTFCDQLEVSLEKKANAKQLVSKSISNRIQKSKSKEELDKNITFIIRNLKEVYTTPENLNDLKDIILQLAIQGK
LVPQDPDDEPASVLIEKINKEKERLIKEKKIRKTKPLPPIKEAEIPFELPKGWEWVRLGEIMIINQRNKLNDNLEVSFVP
MKLIEDGYLSKHSHKKKLWKEVKKGYTHFKENDLVVAKITPCFENRKSAIMKNLYSGYGAGTTELHVLTSYLKEIDMKFF
LYIVKAKNFINQGVSTFTGTAGQQRIRKDFIENFVIGLPPLNEQKQIVKKIDKLMALCNLLENQINKNRNNSELLMKSLQ
RKLFE
>Mature_565_residues
MKKIIDNFQLIFDSREKIQELRNLILNLAVRGKLVPQNSDDEPSSVLIEKIKKEKERLIKEKKIRKKKPLPPIKEEEIPF
ELPESWEWVRLGNIGRIVGGGTPKTKVHAYWENGNIAWLTPADLNGLKSKYISRGRRNITKLGLQNSSAKLLPKGSVLFS
SRAPIGYVAIAQNDLATNQGFKSCVPYIMDMNQYIYYFLMYDAKRINDNASGTTFKEVSGKEVANFIFPLPPLNEQKRIV
NKLDELMTFCDQLEVSLEKKANAKQLVSKSISNRIQKSKSKEELDKNITFIIRNLKEVYTTPENLNDLKDIILQLAIQGK
LVPQDPDDEPASVLIEKINKEKERLIKEKKIRKTKPLPPIKEAEIPFELPKGWEWVRLGEIMIINQRNKLNDNLEVSFVP
MKLIEDGYLSKHSHKKKLWKEVKKGYTHFKENDLVVAKITPCFENRKSAIMKNLYSGYGAGTTELHVLTSYLKEIDMKFF
LYIVKAKNFINQGVSTFTGTAGQQRIRKDFIENFVIGLPPLNEQKQIVKKIDKLMALCNLLENQINKNRNNSELLMKSLQ
RKLFE

Specific function: The M and S subunits together form a methyltransferase (MTase) that methylates two adenine residues in complementary strands of a bipartite DNA recognition sequence. In the presence of the R subunit the complex can also act as an endonuclease, binding to

COG id: COG0732

COG function: function code V; Restriction endonuclease S subunits

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type-I restriction system S methylase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000055 [H]

Pfam domain/function: PF01420 Methylase_S [H]

EC number: NA

Molecular weight: Translated: 65159; Mature: 65159

Theoretical pI: Translated: 10.22; Mature: 10.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKIIDNFQLIFDSREKIQELRNLILNLAVRGKLVPQNSDDEPSSVLIEKIKKEKERLIK
CCHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCEECCCCCCCCHHHHHHHHHHHHHHHHHH
EKKIRKKKPLPPIKEEEIPFELPESWEWVRLGNIGRIVGGGTPKTKVHAYWENGNIAWLT
HHHHHHCCCCCCCCCCCCCCCCCCCCCEEEECCCCEECCCCCCCCEEEEEEECCCEEEEC
PADLNGLKSKYISRGRRNITKLGLQNSSAKLLPKGSVLFSSRAPIGYVAIAQNDLATNQG
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCEEEEEECCCCCCCCC
FKSCVPYIMDMNQYIYYFLMYDAKRINDNASGTTFKEVSGKEVANFIFPLPPLNEQKRIV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCHHHHHHHHCCCCCCCHHHHHH
NKLDELMTFCDQLEVSLEKKANAKQLVSKSISNRIQKSKSKEELDKNITFIIRNLKEVYT
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHC
TPENLNDLKDIILQLAIQGKLVPQDPDDEPASVLIEKINKEKERLIKEKKIRKTKPLPPI
CCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
KEAEIPFELPKGWEWVRLGEIMIINQRNKLNDNLEVSFVPMKLIEDGYLSKHSHKKKLWK
CCCCCCCCCCCCCCEEEECCEEEEECCCCCCCCCEEEEEHHHHHHCCCCCHHHHHHHHHH
EVKKGYTHFKENDLVVAKITPCFENRKSAIMKNLYSGYGAGTTELHVLTSYLKEIDMKFF
HHHHHHCCCCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
LYIVKAKNFINQGVSTFTGTAGQQRIRKDFIENFVIGLPPLNEQKQIVKKIDKLMALCNL
HHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHH
LENQINKNRNNSELLMKSLQRKLFE
HHHHHHCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKKIIDNFQLIFDSREKIQELRNLILNLAVRGKLVPQNSDDEPSSVLIEKIKKEKERLIK
CCHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCEECCCCCCCCHHHHHHHHHHHHHHHHHH
EKKIRKKKPLPPIKEEEIPFELPESWEWVRLGNIGRIVGGGTPKTKVHAYWENGNIAWLT
HHHHHHCCCCCCCCCCCCCCCCCCCCCEEEECCCCEECCCCCCCCEEEEEEECCCEEEEC
PADLNGLKSKYISRGRRNITKLGLQNSSAKLLPKGSVLFSSRAPIGYVAIAQNDLATNQG
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCEEEEEECCCCCCCCC
FKSCVPYIMDMNQYIYYFLMYDAKRINDNASGTTFKEVSGKEVANFIFPLPPLNEQKRIV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCHHHHHHHHCCCCCCCHHHHHH
NKLDELMTFCDQLEVSLEKKANAKQLVSKSISNRIQKSKSKEELDKNITFIIRNLKEVYT
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHC
TPENLNDLKDIILQLAIQGKLVPQDPDDEPASVLIEKINKEKERLIKEKKIRKTKPLPPI
CCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
KEAEIPFELPKGWEWVRLGEIMIINQRNKLNDNLEVSFVPMKLIEDGYLSKHSHKKKLWK
CCCCCCCCCCCCCCEEEECCEEEEECCCCCCCCCEEEEEHHHHHHCCCCCHHHHHHHHHH
EVKKGYTHFKENDLVVAKITPCFENRKSAIMKNLYSGYGAGTTELHVLTSYLKEIDMKFF
HHHHHHCCCCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
LYIVKAKNFINQGVSTFTGTAGQQRIRKDFIENFVIGLPPLNEQKQIVKKIDKLMALCNL
HHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHH
LENQINKNRNNSELLMKSLQRKLFE
HHHHHHCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2642743 [H]