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The map label for this gene is mcpA [H]

Identifier: 220932781

GI number: 220932781

Start: 2085113

End: 2087167

Strand: Reverse

Name: mcpA [H]

Synonym: Hore_19470

Alternate gene names: 220932781

Gene position: 2087167-2085113 (Counterclockwise)

Preceding gene: 220932782

Following gene: 220932780

Centisome position: 80.96

GC content: 37.32

Gene sequence:

>2055_bases
ATGTTCAAGAAGATGGGGCTTAAATGGAAGATTCTGACCGTAGTTTCCCTGGTAATGGTCATTGTTCTTATATCAATTTC
TTTTTTCACTTACAGAAGCACAAAAAATGTGGTAACTACCCAGATCGATAACCGGATCCGGGTAATTAAAATGATGCAGA
AAGATATGATTAATGAGTTTATAACAAGGCTGGAAAACCAGATAAAGTACTTTACTTCTCAGCAGGAAATATATTTTTTC
GTAAATATACTGAACAGTAATATCAATAATAGCCTTGAAGAGGGTCGGTCCTTATCACTGGATAATTATAATTACTCTCA
AATAATAGTGGAAAGAAGTAAGTTATTAGATGAACACACTAAAATAAATGAATCGTTCAAATTTGCCTATTTGACAAATA
CACGGGGTTATGTCATTGCAGATTCAAGGCTTCAGGGTGAAGAGGGTTTAGAAAAATATATATTTAAACAACTACCAGAG
AGTCAATACAAATCGGCAAGGCCTGACCATATATTTAAAAATGAGAAGGGTTCCTATCTCCTGTTTCAGGTTCCCATCAA
GAAAGATAACGATGGGGCTGAAGTAATTGGATATTATGTAATGGGGGTTTCCCTGGATTCATTTGAAACCGGAATCAGGG
AAGGAACCTTGGAAAATGGGGAAATTCAGTTAATAAACTCCGATGGCATAATATTGAGTCATTCTCAAAATAAACTTATT
GGAACCAGAATTAAAAATCCCTGGTTTGAAAAGATGATTAACAGTAACGTCGATTCTATAAAAAAAGTTGTGGGAGATAA
ATATCTTATTCTGGAAAGGCTTGATAAAAGCAAAAAAATATATCTGGCCATTGAGATTCCTGAAAAGGCTATTACAGAAC
CAGTGGGTAGTATACGTAATATTATTATTTACATATCATTGACGGGAATAATAGCAGTGTATCTAAGTGGTTACATATTT
ATCACATGGCAATTTAAGCCCTTTAATAAGTTTTTGTATTCTTTTAACCAGCTTGGCAGTGGCTATCTATATAAAGAATT
ACTCCTTGACAGGCGTTATATCAGGCGTGGTGATGAAATTGGTTTACTCGCCAGGGCCTTTAATAATATGTTTAATCAGT
TGAGGAATATTATTACCAGCATTAATAACACCTCGGGACAGGTCGGTGAATCTTCTAATAAACTACAGGATATATCCAGC
GAGGTTGAAAATATATCCAACCAGGTGGCTGTTTCCATTCAGGAAGTGGCAACAGGTTCTGACAGTCAGGCTGCAAGTGT
TGAAAAGATTAATTATAGAATCCAGAACCTGGCTGCGGGTATAAATAAGCTTGATAATTTTAATAATAAAATGACGGATC
TTTCCGGAAAAATGACCAGTGCTGCCAGGGAAGGGCAGACAGAGATTGATAAGGTTAAAACCCAGATGGAAAATATCAAA
AGTTCTATCCGGCAGGTAGCAACAAGTATTGGCAGGTTAAATTCAATTTCGGAAGAAATTGATTCTATAATAGAGATAAT
AAACAATTTGGGAAAACAGACCAATCTCCTGGCCTTAAATGCTGCCATTGAAGCAGCCCGGGCCGGTGAGGCCGGTCAGG
GTTTTAGTGTTGTGGCCGAAGAGATTAGAAAACTTGCTGAGGAGTCTGTGAATTCTGCTGACAAAATCAGGGGTTTAATA
ATGGAGATAAAAAATGGTACCGGTGAAGCCAGTTCTAAAATGGAAGCAGGGGTTGAAGAAATAGAAAACGGAGAAGTAGT
TGTTAATAAAGCCAGTGAAGCCTTTCACAGAATCAGTGACAGCATTACAGAAGTTGGTAAAGGAATTGAACAGTCAGTTC
AAATTGTAAAAAATATAAACCAGGAAAGTGGGGAAATAGTATCCAGTATAGAAGATATTTCTGCTATCTCTGAGGAAACA
TCAGCCAGTACCCAGGAAGTTGCTGCTGCCAGTGAAGAACAGTTATCGTCTGTTGAAGAACTGGCCGGCCTTGCGGCTTC
ATTATCCAGTATGGCCGAAGAGCTGGAGATTCTTATTAAGAAGTTCAAGGTTTAA

Upstream 100 bases:

>100_bases
AATTAAATTCAGATGGCAAATAATGCTTAATTATTTATTACAACTTACATAATACATTGTAAAGAATAACTGACAGGCTA
TTTAACAGGAGGTAATGGGC

Downstream 100 bases:

>100_bases
AAAAAGTTGCCATAAAACCTTCCCGGTTTTACATAATGGGGGTAATATAGGGGTCATAATGATGGATTTAAATCCATATT
ATGACCCCTTATTTTTTCAT

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: H1 [H]

Number of amino acids: Translated: 684; Mature: 684

Protein sequence:

>684_residues
MFKKMGLKWKILTVVSLVMVIVLISISFFTYRSTKNVVTTQIDNRIRVIKMMQKDMINEFITRLENQIKYFTSQQEIYFF
VNILNSNINNSLEEGRSLSLDNYNYSQIIVERSKLLDEHTKINESFKFAYLTNTRGYVIADSRLQGEEGLEKYIFKQLPE
SQYKSARPDHIFKNEKGSYLLFQVPIKKDNDGAEVIGYYVMGVSLDSFETGIREGTLENGEIQLINSDGIILSHSQNKLI
GTRIKNPWFEKMINSNVDSIKKVVGDKYLILERLDKSKKIYLAIEIPEKAITEPVGSIRNIIIYISLTGIIAVYLSGYIF
ITWQFKPFNKFLYSFNQLGSGYLYKELLLDRRYIRRGDEIGLLARAFNNMFNQLRNIITSINNTSGQVGESSNKLQDISS
EVENISNQVAVSIQEVATGSDSQAASVEKINYRIQNLAAGINKLDNFNNKMTDLSGKMTSAAREGQTEIDKVKTQMENIK
SSIRQVATSIGRLNSISEEIDSIIEIINNLGKQTNLLALNAAIEAARAGEAGQGFSVVAEEIRKLAEESVNSADKIRGLI
MEIKNGTGEASSKMEAGVEEIENGEVVVNKASEAFHRISDSITEVGKGIEQSVQIVKNINQESGEIVSSIEDISAISEET
SASTQEVAAASEEQLSSVEELAGLAASLSSMAEELEILIKKFKV

Sequences:

>Translated_684_residues
MFKKMGLKWKILTVVSLVMVIVLISISFFTYRSTKNVVTTQIDNRIRVIKMMQKDMINEFITRLENQIKYFTSQQEIYFF
VNILNSNINNSLEEGRSLSLDNYNYSQIIVERSKLLDEHTKINESFKFAYLTNTRGYVIADSRLQGEEGLEKYIFKQLPE
SQYKSARPDHIFKNEKGSYLLFQVPIKKDNDGAEVIGYYVMGVSLDSFETGIREGTLENGEIQLINSDGIILSHSQNKLI
GTRIKNPWFEKMINSNVDSIKKVVGDKYLILERLDKSKKIYLAIEIPEKAITEPVGSIRNIIIYISLTGIIAVYLSGYIF
ITWQFKPFNKFLYSFNQLGSGYLYKELLLDRRYIRRGDEIGLLARAFNNMFNQLRNIITSINNTSGQVGESSNKLQDISS
EVENISNQVAVSIQEVATGSDSQAASVEKINYRIQNLAAGINKLDNFNNKMTDLSGKMTSAAREGQTEIDKVKTQMENIK
SSIRQVATSIGRLNSISEEIDSIIEIINNLGKQTNLLALNAAIEAARAGEAGQGFSVVAEEIRKLAEESVNSADKIRGLI
MEIKNGTGEASSKMEAGVEEIENGEVVVNKASEAFHRISDSITEVGKGIEQSVQIVKNINQESGEIVSSIEDISAISEET
SASTQEVAAASEEQLSSVEELAGLAASLSSMAEELEILIKKFKV
>Mature_684_residues
MFKKMGLKWKILTVVSLVMVIVLISISFFTYRSTKNVVTTQIDNRIRVIKMMQKDMINEFITRLENQIKYFTSQQEIYFF
VNILNSNINNSLEEGRSLSLDNYNYSQIIVERSKLLDEHTKINESFKFAYLTNTRGYVIADSRLQGEEGLEKYIFKQLPE
SQYKSARPDHIFKNEKGSYLLFQVPIKKDNDGAEVIGYYVMGVSLDSFETGIREGTLENGEIQLINSDGIILSHSQNKLI
GTRIKNPWFEKMINSNVDSIKKVVGDKYLILERLDKSKKIYLAIEIPEKAITEPVGSIRNIIIYISLTGIIAVYLSGYIF
ITWQFKPFNKFLYSFNQLGSGYLYKELLLDRRYIRRGDEIGLLARAFNNMFNQLRNIITSINNTSGQVGESSNKLQDISS
EVENISNQVAVSIQEVATGSDSQAASVEKINYRIQNLAAGINKLDNFNNKMTDLSGKMTSAAREGQTEIDKVKTQMENIK
SSIRQVATSIGRLNSISEEIDSIIEIINNLGKQTNLLALNAAIEAARAGEAGQGFSVVAEEIRKLAEESVNSADKIRGLI
MEIKNGTGEASSKMEAGVEEIENGEVVVNKASEAFHRISDSITEVGKGIEQSVQIVKNINQESGEIVSSIEDISAISEET
SASTQEVAAASEEQLSSVEELAGLAASLSSMAEELEILIKKFKV

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788194, Length=361, Percent_Identity=25.207756232687, Blast_Score=105, Evalue=8e-24,
Organism=Escherichia coli, GI2367378, Length=311, Percent_Identity=27.9742765273312, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI1789453, Length=343, Percent_Identity=27.6967930029155, Blast_Score=102, Evalue=1e-22,
Organism=Escherichia coli, GI1788195, Length=281, Percent_Identity=26.6903914590747, Blast_Score=99, Evalue=8e-22,
Organism=Escherichia coli, GI1787690, Length=379, Percent_Identity=25.5936675461741, Blast_Score=89, Evalue=9e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004010
- InterPro:   IPR003122
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR022094 [H]

Pfam domain/function: PF02743 Cache_1; PF00672 HAMP; PF12332 McpA_N; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 76506; Mature: 76506

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKKMGLKWKILTVVSLVMVIVLISISFFTYRSTKNVVTTQIDNRIRVIKMMQKDMINEF
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHCCHHHHHHHHHHHHHHHH
ITRLENQIKYFTSQQEIYFFVNILNSNINNSLEEGRSLSLDNYNYSQIIVERSKLLDEHT
HHHHHHHHHHHCCCCCEEEEEEHHHCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHH
KINESFKFAYLTNTRGYVIADSRLQGEEGLEKYIFKQLPESQYKSARPDHIFKNEKGSYL
HCCCCEEEEEEECCCCEEEECCCCCCHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCCCEE
LFQVPIKKDNDGAEVIGYYVMGVSLDSFETGIREGTLENGEIQLINSDGIILSHSQNKLI
EEEECCCCCCCCHHHHHHHHHCCCHHHHHHHHHCCCCCCCCEEEEECCCEEEECCCCCEE
GTRIKNPWFEKMINSNVDSIKKVVGDKYLILERLDKSKKIYLAIEIPEKAITEPVGSIRN
HHHCCCHHHHHHHCCCHHHHHHHHCCHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHHH
IIIYISLTGIIAVYLSGYIFITWQFKPFNKFLYSFNQLGSGYLYKELLLDRRYIRRGDEI
EEEEEEHHHHHHHHHCCEEEEEEEECHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHH
GLLARAFNNMFNQLRNIITSINNTSGQVGESSNKLQDISSEVENISNQVAVSIQEVATGS
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHEEHHHHHCCC
DSQAASVEKINYRIQNLAAGINKLDNFNNKMTDLSGKMTSAAREGQTEIDKVKTQMENIK
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHCCCHHHHHHHHHHHHHH
SSIRQVATSIGRLNSISEEIDSIIEIINNLGKQTNLLALNAAIEAARAGEAGQGFSVVAE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHCCCCCCCHHHHHH
EIRKLAEESVNSADKIRGLIMEIKNGTGEASSKMEAGVEEIENGEVVVNKASEAFHRISD
HHHHHHHHHCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCEEEECHHHHHHHHHH
SITEVGKGIEQSVQIVKNINQESGEIVSSIEDISAISEETSASTQEVAAASEEQLSSVEE
HHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHH
LAGLAASLSSMAEELEILIKKFKV
HHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MFKKMGLKWKILTVVSLVMVIVLISISFFTYRSTKNVVTTQIDNRIRVIKMMQKDMINEF
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHCCHHHHHHHHHHHHHHHH
ITRLENQIKYFTSQQEIYFFVNILNSNINNSLEEGRSLSLDNYNYSQIIVERSKLLDEHT
HHHHHHHHHHHCCCCCEEEEEEHHHCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHH
KINESFKFAYLTNTRGYVIADSRLQGEEGLEKYIFKQLPESQYKSARPDHIFKNEKGSYL
HCCCCEEEEEEECCCCEEEECCCCCCHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCCCEE
LFQVPIKKDNDGAEVIGYYVMGVSLDSFETGIREGTLENGEIQLINSDGIILSHSQNKLI
EEEECCCCCCCCHHHHHHHHHCCCHHHHHHHHHCCCCCCCCEEEEECCCEEEECCCCCEE
GTRIKNPWFEKMINSNVDSIKKVVGDKYLILERLDKSKKIYLAIEIPEKAITEPVGSIRN
HHHCCCHHHHHHHCCCHHHHHHHHCCHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHHH
IIIYISLTGIIAVYLSGYIFITWQFKPFNKFLYSFNQLGSGYLYKELLLDRRYIRRGDEI
EEEEEEHHHHHHHHHCCEEEEEEEECHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHH
GLLARAFNNMFNQLRNIITSINNTSGQVGESSNKLQDISSEVENISNQVAVSIQEVATGS
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHEEHHHHHCCC
DSQAASVEKINYRIQNLAAGINKLDNFNNKMTDLSGKMTSAAREGQTEIDKVKTQMENIK
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHCCCHHHHHHHHHHHHHH
SSIRQVATSIGRLNSISEEIDSIIEIINNLGKQTNLLALNAAIEAARAGEAGQGFSVVAE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHCCCCCCCHHHHHH
EIRKLAEESVNSADKIRGLIMEIKNGTGEASSKMEAGVEEIENGEVVVNKASEAFHRISD
HHHHHHHHHCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCEEEECHHHHHHHHHH
SITEVGKGIEQSVQIVKNINQESGEIVSSIEDISAISEETSASTQEVAAASEEQLSSVEE
HHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHH
LAGLAASLSSMAEELEILIKKFKV
HHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8188684; 9384377 [H]