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The map label for this gene is yknU [H]

Identifier: 220932764

GI number: 220932764

Start: 2066377

End: 2067117

Strand: Reverse

Name: yknU [H]

Synonym: Hore_19300

Alternate gene names: 220932764

Gene position: 2067117-2066377 (Counterclockwise)

Preceding gene: 220932765

Following gene: 220932763

Centisome position: 80.18

GC content: 43.18

Gene sequence:

>741_bases
ATGAAAAATGTAAAATTACTGTGGCGGTTTATGAAGGGGAACAGGTTAACTTATTTAGGGGCTATCCTCAGCACAGGGTT
GGCTACCCTGTTTACCATTTTAAACCCCCAGATATTGAGGGTTACAATTGATTCTGTTATCGGGGATAAACCAGCTGAGC
TTCCCCTCTGGGTAATGAGGTTTATTGATGGTTTTAGTTTTACCCAAAAACTGGTCGGGGCTGGATTAACTCTTCTTATA
ATAACAGTTTTACGCGGGTTTTTCCTCTATCTAAAGGGTAAATGGTCAGCAGTAGCTGCTGAAAATACTGCCCGCAATAT
CCGGAACTCGATTTATGATCATTTGCAGCATTTACCATATGGTTACCATGTCAGGGCTGAAACTGGAGATCTTATTCAAC
GTTGTACCTCTGACCTGGAAACATTAAGGCGATTTATGGCAGTTCAGCTGGTTGAGATCGGCCGGGCCCTTTTTATCCTG
GGGTTGGCTTTACCGGCTATGATAGCCCTGGATACAACCATGACTCTGATTGCTATGCTAATTGTCCCGGTTATTTTCGT
CTTTTCAGTTGTCTTCTTTGTTAAAGTAAAGTCGGCTTTTAAAAAGGCCGATGAAGCGGAAGGTCGGATGTCAACAGTCC
TCCAGGAGAATTTAACAGGGGTCAGGGTTGTCAGGGCCTTTGGCCGGGAATCTTTCGAGATCGAGAAGTTTGATAAAAAA
ATAAGAAGTATCGTGATCTGA

Upstream 100 bases:

>100_bases
ATTACAAACTAATTTTGGGAAAGCTCACAGGTAACTAAATGTTTAGATAAAGTAATTATAAAGTACTTATCAATTAATAG
AATTAATAGAAGGTGATATT

Downstream 100 bases:

>100_bases
CTTATCGATTAATTAAATTACTGGCCTGGTACTGGTCAACTTCAGACTTAATGTGTATGTTTCAGATGGGAATTGTCCTG
GTGGGAGGAGTATATTTTGC

Product: ABC transporter transmembrane region

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 246; Mature: 246

Protein sequence:

>246_residues
MKNVKLLWRFMKGNRLTYLGAILSTGLATLFTILNPQILRVTIDSVIGDKPAELPLWVMRFIDGFSFTQKLVGAGLTLLI
ITVLRGFFLYLKGKWSAVAAENTARNIRNSIYDHLQHLPYGYHVRAETGDLIQRCTSDLETLRRFMAVQLVEIGRALFIL
GLALPAMIALDTTMTLIAMLIVPVIFVFSVVFFVKVKSAFKKADEAEGRMSTVLQENLTGVRVVRAFGRESFEIEKFDKK
IRSIVI

Sequences:

>Translated_246_residues
MKNVKLLWRFMKGNRLTYLGAILSTGLATLFTILNPQILRVTIDSVIGDKPAELPLWVMRFIDGFSFTQKLVGAGLTLLI
ITVLRGFFLYLKGKWSAVAAENTARNIRNSIYDHLQHLPYGYHVRAETGDLIQRCTSDLETLRRFMAVQLVEIGRALFIL
GLALPAMIALDTTMTLIAMLIVPVIFVFSVVFFVKVKSAFKKADEAEGRMSTVLQENLTGVRVVRAFGRESFEIEKFDKK
IRSIVI
>Mature_246_residues
MKNVKLLWRFMKGNRLTYLGAILSTGLATLFTILNPQILRVTIDSVIGDKPAELPLWVMRFIDGFSFTQKLVGAGLTLLI
ITVLRGFFLYLKGKWSAVAAENTARNIRNSIYDHLQHLPYGYHVRAETGDLIQRCTSDLETLRRFMAVQLVEIGRALFIL
GLALPAMIALDTTMTLIAMLIVPVIFVFSVVFFVKVKSAFKKADEAEGRMSTVLQENLTGVRVVRAFGRESFEIEKFDKK
IRSIVI

Specific function: Involved In Lipid A Export And Possibly Also In Glycerophospholipid Export And For Biogenesis Of The Outer Membrane. Transmembrane Domains (Tmd) Form A Pore In The Inner Membrane And The ATP-Binding Domain (Nbd) Is Responsible For Energy Generation. [C]

COG id: COG1132

COG function: function code V; ABC-type multidrug transport system, ATPase and permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Caenorhabditis elegans, GI17543740, Length=138, Percent_Identity=25.3623188405797, Blast_Score=67, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017940
- InterPro:   IPR001140
- InterPro:   IPR011527
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00664 ABC_membrane; PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 27747; Mature: 27747

Theoretical pI: Translated: 10.56; Mature: 10.56

Prosite motif: PS50929 ABC_TM1F

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHCC
>Mature Secondary Structure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HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]