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The map label for this gene is ccpA [H]

Identifier: 220932659

GI number: 220932659

Start: 1946127

End: 1947287

Strand: Reverse

Name: ccpA [H]

Synonym: Hore_18230

Alternate gene names: 220932659

Gene position: 1947287-1946127 (Counterclockwise)

Preceding gene: 220932660

Following gene: 220932658

Centisome position: 75.53

GC content: 44.36

Gene sequence:

>1161_bases
ATGGTTACAATAAAAGATATTGCAGAACGGGCCGGAGTCTCTACCGCTACTGTATCCCGGGTTTTAAATAACAGTCCCCG
GGTTAAAGAGGAGACCAGGGTCCGGATTCTTGAGATTATTAAGGAGACCGGTTATGGGCGGTACCGGAAGGGTATTAAAA
AGAGCCCTGATAGTAAGGTGACTATCAGGGAGGTAGCAAGGGAGGCCGGGGTATCAGTGGCCACTGTTTCCCGGGTCATA
AATGGAGACAGTGCTGTGAGTCCTCAAACCCGGAACAGGGTAAAAAAGGCCATGCAGGCCCTGAACTATCACCCCAATTT
ACTGGGACGCCAGCTGAGGAGAAGGGAAACAAAAAGTATTGGAATTATTATCCCCGAGATATCAAACTTTTTCTTTGCCC
GGGTCATCAAAGGGATTGAAAATGTGGCTGAATGTGAAAACTATAACGTAATTTTGATGGAGAGTAACAGAAAGGACCAT
ATCGCGGCCATAAAGGCCCTGTATGAGCGGCGGATTGATGGTTTAATCTATATGACCGGCCACCTGACAAAACAGGAGAT
TGATTTTTTCAGAGAGCTCAAATTACCGGTTGTACTCCTTTCCCAGGACTTTTGTGCTCCTGATATACCTTCAGTAAATA
TTAATAATAGGGAAGCAGCGTTTGAAGCTGTGACCTACCTTCTAAAAAAGGGGTATAAAAGGATTGCTTTTCTGGGTGGT
CCTTTTTCTGACAGGGTATCTGTTTTCAACCGGTTTAAAGGATACTGTGGGGCTTTAAAAGAGTATGGCCTAAAACCCGA
TAAGCACTTGATAAAAGAAGGTGAGTTTAGCCTGGAAAGCGGTTATGATATGTGCTACCGGCTCCTTCAGGAAGGTCCAG
AAGTTGAGGCAATATTTGCTGCCAATGATGAAATTGCCATTGGTGTTATCAAGGCCCTTACCGTGAAAGGATATAAAATA
CCCCGGGATATTGCTGTGATTGGCTTTGATGACCTCCCTGTGGCCAGGTTTACAGTTCCTTCTCTCACCACGGTCCATCA
ACCTATTTATAAAATGGGCCGGGAAGGAATGAATCTCCTCTTGAAACTTATCAAAAATATTCCTTTAAAGGAATCCCATG
TGACCTTGAATCATAAACTTATTATCAGGGATTCGGCCTGA

Upstream 100 bases:

>100_bases
CCCCGGCTTTTTTTAAAACTCAGGATGCTTGACACCTGAAATTTTCCGGTGATATAATGTAATGTAAAGGATTACATACA
TCATACAGGGAGACCTGAAT

Downstream 100 bases:

>100_bases
CAGGGTGATATTGTTGCCTGGTTTTACGAATCGAAAAATCAATAATAAAAGCCTTTAAAAGTTTAAAATATTTTTTCTAC
ATATAAATAATAAATATCAC

Product: LacI family transcriptional regulator

Products: NA

Alternate protein names: Catabolite control protein [H]

Number of amino acids: Translated: 386; Mature: 386

Protein sequence:

>386_residues
MVTIKDIAERAGVSTATVSRVLNNSPRVKEETRVRILEIIKETGYGRYRKGIKKSPDSKVTIREVAREAGVSVATVSRVI
NGDSAVSPQTRNRVKKAMQALNYHPNLLGRQLRRRETKSIGIIIPEISNFFFARVIKGIENVAECENYNVILMESNRKDH
IAAIKALYERRIDGLIYMTGHLTKQEIDFFRELKLPVVLLSQDFCAPDIPSVNINNREAAFEAVTYLLKKGYKRIAFLGG
PFSDRVSVFNRFKGYCGALKEYGLKPDKHLIKEGEFSLESGYDMCYRLLQEGPEVEAIFAANDEIAIGVIKALTVKGYKI
PRDIAVIGFDDLPVARFTVPSLTTVHQPIYKMGREGMNLLLKLIKNIPLKESHVTLNHKLIIRDSA

Sequences:

>Translated_386_residues
MVTIKDIAERAGVSTATVSRVLNNSPRVKEETRVRILEIIKETGYGRYRKGIKKSPDSKVTIREVAREAGVSVATVSRVI
NGDSAVSPQTRNRVKKAMQALNYHPNLLGRQLRRRETKSIGIIIPEISNFFFARVIKGIENVAECENYNVILMESNRKDH
IAAIKALYERRIDGLIYMTGHLTKQEIDFFRELKLPVVLLSQDFCAPDIPSVNINNREAAFEAVTYLLKKGYKRIAFLGG
PFSDRVSVFNRFKGYCGALKEYGLKPDKHLIKEGEFSLESGYDMCYRLLQEGPEVEAIFAANDEIAIGVIKALTVKGYKI
PRDIAVIGFDDLPVARFTVPSLTTVHQPIYKMGREGMNLLLKLIKNIPLKESHVTLNHKLIIRDSA
>Mature_386_residues
MVTIKDIAERAGVSTATVSRVLNNSPRVKEETRVRILEIIKETGYGRYRKGIKKSPDSKVTIREVAREAGVSVATVSRVI
NGDSAVSPQTRNRVKKAMQALNYHPNLLGRQLRRRETKSIGIIIPEISNFFFARVIKGIENVAECENYNVILMESNRKDH
IAAIKALYERRIDGLIYMTGHLTKQEIDFFRELKLPVVLLSQDFCAPDIPSVNINNREAAFEAVTYLLKKGYKRIAFLGG
PFSDRVSVFNRFKGYCGALKEYGLKPDKHLIKEGEFSLESGYDMCYRLLQEGPEVEAIFAANDEIAIGVIKALTVKGYKI
PRDIAVIGFDDLPVARFTVPSLTTVHQPIYKMGREGMNLLLKLIKNIPLKESHVTLNHKLIIRDSA

Specific function: Transcriptional regulator involved in both the repression of carbohydrate utilization genes such as the alpha- amylase (amyE) and the acetyl-coenzyme A synthetase (acsA); and in the positive regulation of genes involved in excretion of excess carbon such

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790369, Length=336, Percent_Identity=33.9285714285714, Blast_Score=201, Evalue=6e-53,
Organism=Escherichia coli, GI1790194, Length=331, Percent_Identity=33.8368580060423, Blast_Score=185, Evalue=5e-48,
Organism=Escherichia coli, GI1789068, Length=331, Percent_Identity=32.3262839879154, Blast_Score=176, Evalue=2e-45,
Organism=Escherichia coli, GI1787948, Length=330, Percent_Identity=30.9090909090909, Blast_Score=172, Evalue=3e-44,
Organism=Escherichia coli, GI1788474, Length=319, Percent_Identity=34.1692789968652, Blast_Score=172, Evalue=5e-44,
Organism=Escherichia coli, GI1789202, Length=328, Percent_Identity=32.3170731707317, Blast_Score=159, Evalue=4e-40,
Organism=Escherichia coli, GI1790715, Length=327, Percent_Identity=29.3577981651376, Blast_Score=152, Evalue=5e-38,
Organism=Escherichia coli, GI1786540, Length=316, Percent_Identity=30.6962025316456, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI48994940, Length=318, Percent_Identity=29.559748427673, Blast_Score=138, Evalue=6e-34,
Organism=Escherichia coli, GI1787580, Length=332, Percent_Identity=28.3132530120482, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI1787906, Length=336, Percent_Identity=26.4880952380952, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1789456, Length=321, Percent_Identity=29.2834890965732, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1790689, Length=309, Percent_Identity=26.8608414239482, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1786268, Length=277, Percent_Identity=27.4368231046931, Blast_Score=91, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006377
- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 43494; Mature: 43494

Theoretical pI: Translated: 10.09; Mature: 10.09

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVTIKDIAERAGVSTATVSRVLNNSPRVKEETRVRILEIIKETGYGRYRKGIKKSPDSKV
CCCHHHHHHHCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCH
TIREVAREAGVSVATVSRVINGDSAVSPQTRNRVKKAMQALNYHPNLLGRQLRRRETKSI
HHHHHHHHHCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCC
GIIIPEISNFFFARVIKGIENVAECENYNVILMESNRKDHIAAIKALYERRIDGLIYMTG
EEEECHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHCCEEEEEC
HLTKQEIDFFRELKLPVVLLSQDFCAPDIPSVNINNREAAFEAVTYLLKKGYKRIAFLGG
CCCHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECC
PFSDRVSVFNRFKGYCGALKEYGLKPDKHLIKEGEFSLESGYDMCYRLLQEGPEVEAIFA
CCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCHHHHHHHHHCCCCEEEEEE
ANDEIAIGVIKALTVKGYKIPRDIAVIGFDDLPVARFTVPSLTTVHQPIYKMGREGMNLL
CCCCCHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHEECCCHHHHHHHHHHHHHHHHHHH
LKLIKNIPLKESHVTLNHKLIIRDSA
HHHHHCCCCCCCEEEEEEEEEEEECC
>Mature Secondary Structure
MVTIKDIAERAGVSTATVSRVLNNSPRVKEETRVRILEIIKETGYGRYRKGIKKSPDSKV
CCCHHHHHHHCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCH
TIREVAREAGVSVATVSRVINGDSAVSPQTRNRVKKAMQALNYHPNLLGRQLRRRETKSI
HHHHHHHHHCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCC
GIIIPEISNFFFARVIKGIENVAECENYNVILMESNRKDHIAAIKALYERRIDGLIYMTG
EEEECHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHCCEEEEEC
HLTKQEIDFFRELKLPVVLLSQDFCAPDIPSVNINNREAAFEAVTYLLKKGYKRIAFLGG
CCCHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECC
PFSDRVSVFNRFKGYCGALKEYGLKPDKHLIKEGEFSLESGYDMCYRLLQEGPEVEAIFA
CCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCHHHHHHHHHCCCCEEEEEE
ANDEIAIGVIKALTVKGYKIPRDIAVIGFDDLPVARFTVPSLTTVHQPIYKMGREGMNLL
CCCCCHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHEECCCHHHHHHHHHHHHHHHHHHH
LKLIKNIPLKESHVTLNHKLIIRDSA
HHHHHCCCCCCCEEEEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8200532 [H]