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The map label for this gene is tdk [H]

Identifier: 220932635

GI number: 220932635

Start: 1923550

End: 1924146

Strand: Reverse

Name: tdk [H]

Synonym: Hore_17990

Alternate gene names: 220932635

Gene position: 1924146-1923550 (Counterclockwise)

Preceding gene: 220932636

Following gene: 220932634

Centisome position: 74.63

GC content: 44.89

Gene sequence:

>597_bases
ATGTACCAGATAAACAATACTGGATGGATAGAGGTTATTACCGGTCCCATGTACTGTGGTAAAAGTGAAGAACTGATCCG
GCGGTTGCGCCGGGTTGAAATAGCCAGACAGAAAGCTCATGTTTTTAAACCGGTTATAGACAACCGCTATAGTAATAAGG
ATGTTGTTTCCCATAATGGGGAAAGAATTGAGGCTATACCGGTCAATCACCCTGAGGAAATTTTACAGAGGATTGATAAA
AATACCGAAGTGGTCGGAATAGATGAAGTACAGTTTTTTAGTAACGGGATCATTTCTATCTGTGAACAACTTGCTGATGA
GGGGAAGAGGGTTATTGTGGCCGGCCTGGATCGCGATTTCAGGGGGGAACCCTTTGGCCCGGTACCGGAACTACTGGCCA
GGGCTGAATATGTCGATAAACTCCATGCAATCTGTGTAAAATGTGGGGAACTGGCCAGCCGTACTCAGCGACTGATTGAT
GGAGAACCAGCTTCTTACGATGATCCCGTAATTATGGTTGGGGCTGAAGAGGTATATGAAGCCCGTTGTCGAAAATGCCA
TGAAGTAAAGAATAAAAGGGGAGAAAAGAATGAGTGA

Upstream 100 bases:

>100_bases
TAAATTATTTAAATCAAGGATTTTCATAATTGATGAATAAATATTGACAGCAGTTTAGATGGATTAGTCAAAATCAACGT
TTTTAAGAGGTGGAGAGGAG

Downstream 100 bases:

>100_bases
ACCACAATACGGTGGTCAGGCTGTTATTGAAGGTGTAATGATGAGAGGTAAGGACAGGGCAGCCATAGCTGTCCGTAAAC
CTACGGATGAAATTGTTGTG

Product: Thymidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 198; Mature: 198

Protein sequence:

>198_residues
MYQINNTGWIEVITGPMYCGKSEELIRRLRRVEIARQKAHVFKPVIDNRYSNKDVVSHNGERIEAIPVNHPEEILQRIDK
NTEVVGIDEVQFFSNGIISICEQLADEGKRVIVAGLDRDFRGEPFGPVPELLARAEYVDKLHAICVKCGELASRTQRLID
GEPASYDDPVIMVGAEEVYEARCRKCHEVKNKRGEKNE

Sequences:

>Translated_198_residues
MYQINNTGWIEVITGPMYCGKSEELIRRLRRVEIARQKAHVFKPVIDNRYSNKDVVSHNGERIEAIPVNHPEEILQRIDK
NTEVVGIDEVQFFSNGIISICEQLADEGKRVIVAGLDRDFRGEPFGPVPELLARAEYVDKLHAICVKCGELASRTQRLID
GEPASYDDPVIMVGAEEVYEARCRKCHEVKNKRGEKNE
>Mature_198_residues
MYQINNTGWIEVITGPMYCGKSEELIRRLRRVEIARQKAHVFKPVIDNRYSNKDVVSHNGERIEAIPVNHPEEILQRIDK
NTEVVGIDEVQFFSNGIISICEQLADEGKRVIVAGLDRDFRGEPFGPVPELLARAEYVDKLHAICVKCGELASRTQRLID
GEPASYDDPVIMVGAEEVYEARCRKCHEVKNKRGEKNE

Specific function: Phosphorylates Both Thymidine And Deoxyuridine. [C]

COG id: COG1435

COG function: function code F; Thymidine kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thymidine kinase family [H]

Homologues:

Organism=Homo sapiens, GI164698438, Length=180, Percent_Identity=40.5555555555556, Blast_Score=125, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17543396, Length=199, Percent_Identity=33.1658291457286, Blast_Score=101, Evalue=3e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001267
- InterPro:   IPR020633
- InterPro:   IPR020634 [H]

Pfam domain/function: PF00265 TK [H]

EC number: =2.7.1.21 [H]

Molecular weight: Translated: 22548; Mature: 22548

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: PS00603 TK_CELLULAR_TYPE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYQINNTGWIEVITGPMYCGKSEELIRRLRRVEIARQKAHVFKPVIDNRYSNKDVVSHNG
CEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCCC
ERIEAIPVNHPEEILQRIDKNTEVVGIDEVQFFSNGIISICEQLADEGKRVIVAGLDRDF
CEEEEECCCCHHHHHHHHCCCCEEEECHHHHHHHCCHHHHHHHHHHCCCEEEEEECCCCC
RGEPFGPVPELLARAEYVDKLHAICVKCGELASRTQRLIDGEPASYDDPVIMVGAEEVYE
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECHHHHHH
ARCRKCHEVKNKRGEKNE
HHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MYQINNTGWIEVITGPMYCGKSEELIRRLRRVEIARQKAHVFKPVIDNRYSNKDVVSHNG
CEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCCC
ERIEAIPVNHPEEILQRIDKNTEVVGIDEVQFFSNGIISICEQLADEGKRVIVAGLDRDF
CEEEEECCCCHHHHHHHHCCCCEEEECHHHHHHHCCHHHHHHHHHHCCCEEEEEECCCCC
RGEPFGPVPELLARAEYVDKLHAICVKCGELASRTQRLIDGEPASYDDPVIMVGAEEVYE
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECHHHHHH
ARCRKCHEVKNKRGEKNE
HHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12552129 [H]