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The map label for this gene is atpB2 [H]

Identifier: 220932623

GI number: 220932623

Start: 1913262

End: 1913912

Strand: Reverse

Name: atpB2 [H]

Synonym: Hore_17870

Alternate gene names: 220932623

Gene position: 1913912-1913262 (Counterclockwise)

Preceding gene: 220932624

Following gene: 220932622

Centisome position: 74.24

GC content: 43.47

Gene sequence:

>651_bases
ATGAATCCCGGACCTAAGGTAGTAACTCAATTTATGGGGATGCCGATAACCGATACCCTGATTGTTTCCTGGGTAGTGGT
TATCCTGTTGATAATATTTTCAAAGATTGTTACCAGGCGCCTTGAAATGGTGCCGGGAAGGCTTCAAAGTGCTGTAGAAC
TTTTGATTACCTCTATTGAAGATCAGATAGAGACAATGCTTCCGGGCAGAGGAAGTAAGTTTTTGCCCTTTATTGCCACA
ATTTTTATTTATATTGGAGTGTCCAATATTATTGGAGTGATTCCGGGTGTCGCCAACCCGACCGGGGACTTAAATACAAC
CCTCGGGTTAGCCCTGGTTGTCTTTCTGGTAAGCCAGTATTATGGTGTCAGGAAAAAGGGGCTCTGGGGATATCTAAAGG
GTTTTGGTGAGCCTGTAGTCTTTATGTTACCGATAAATATTATTGGAGAACTGGCTAAGCCCATCTCCCATTCTTTCCGT
CTTTTTGGAAATATTGTAGCCGGGGGTATACTGCTGGGAATTGTATTTCAATTTGCTCCCTGGCTTATCCCTGTACCCTT
ACATGCCTGGTTTGATCTTTTTATCGGTCTGGTGCAGGCCCTGATTTTTGGGATGCTGGCTATAGCTTATATCTCCATTG
CTGAATCTTAA

Upstream 100 bases:

>100_bases
AAATACACCATTCTGGGAACAGGAATTATAGAATATGCCAGTGATTGGTGGCATCGCAAACTAGAACATCTGGAAGAAAT
AGATAAAAGGAGGAATTGGG

Downstream 100 bases:

>100_bases
GGTATTAACATTGGTTCAATGAAAACCAATGCTAAACATAATTAAACATAATTTATCTGTTTATCATGGTGAAAGGAGGA
ATAAACAATGGTACAGTTTT

Product: ATP synthase F0 subunit A

Products: ADP; phosphate; H+

Alternate protein names: ATP synthase F0 sector subunit a 2; F-ATPase subunit 6 2 [H]

Number of amino acids: Translated: 216; Mature: 216

Protein sequence:

>216_residues
MNPGPKVVTQFMGMPITDTLIVSWVVVILLIIFSKIVTRRLEMVPGRLQSAVELLITSIEDQIETMLPGRGSKFLPFIAT
IFIYIGVSNIIGVIPGVANPTGDLNTTLGLALVVFLVSQYYGVRKKGLWGYLKGFGEPVVFMLPINIIGELAKPISHSFR
LFGNIVAGGILLGIVFQFAPWLIPVPLHAWFDLFIGLVQALIFGMLAIAYISIAES

Sequences:

>Translated_216_residues
MNPGPKVVTQFMGMPITDTLIVSWVVVILLIIFSKIVTRRLEMVPGRLQSAVELLITSIEDQIETMLPGRGSKFLPFIAT
IFIYIGVSNIIGVIPGVANPTGDLNTTLGLALVVFLVSQYYGVRKKGLWGYLKGFGEPVVFMLPINIIGELAKPISHSFR
LFGNIVAGGILLGIVFQFAPWLIPVPLHAWFDLFIGLVQALIFGMLAIAYISIAES
>Mature_216_residues
MNPGPKVVTQFMGMPITDTLIVSWVVVILLIIFSKIVTRRLEMVPGRLQSAVELLITSIEDQIETMLPGRGSKFLPFIAT
IFIYIGVSNIIGVIPGVANPTGDLNTTLGLALVVFLVSQYYGVRKKGLWGYLKGFGEPVVFMLPINIIGELAKPISHSFR
LFGNIVAGGILLGIVFQFAPWLIPVPLHAWFDLFIGLVQALIFGMLAIAYISIAES

Specific function: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane [H]

COG id: COG0356

COG function: function code C; F0F1-type ATP synthase, subunit a

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase A chain family [H]

Homologues:

Organism=Escherichia coli, GI1790176, Length=209, Percent_Identity=30.622009569378, Blast_Score=90, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000568 [H]

Pfam domain/function: PF00119 ATP-synt_A [H]

EC number: 3.6.3.14

Molecular weight: Translated: 23586; Mature: 23586

Theoretical pI: Translated: 9.41; Mature: 9.41

Prosite motif: PS00449 ATPASE_A

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPGPKVVTQFMGMPITDTLIVSWVVVILLIIFSKIVTRRLEMVPGRLQSAVELLITSIE
CCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
DQIETMLPGRGSKFLPFIATIFIYIGVSNIIGVIPGVANPTGDLNTTLGLALVVFLVSQY
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHH
YGVRKKGLWGYLKGFGEPVVFMLPINIIGELAKPISHSFRLFGNIVAGGILLGIVFQFAP
HCCHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WLIPVPLHAWFDLFIGLVQALIFGMLAIAYISIAES
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNPGPKVVTQFMGMPITDTLIVSWVVVILLIIFSKIVTRRLEMVPGRLQSAVELLITSIE
CCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
DQIETMLPGRGSKFLPFIATIFIYIGVSNIIGVIPGVANPTGDLNTTLGLALVVFLVSQY
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHH
YGVRKKGLWGYLKGFGEPVVFMLPINIIGELAKPISHSFRLFGNIVAGGILLGIVFQFAP
HCCHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WLIPVPLHAWFDLFIGLVQALIFGMLAIAYISIAES
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: Borate; diphosphate; HCO3- [C]

Metal ions: Co2+; Fe2+; Mn2+; Zn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Ca2+; CN-; Efrapeptin; Ethidiumbromide; Guanidines analogs; Oligomycin; Quercetin; Trialkyl tin derivatives; Venturicidin [C]

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA