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The map label for this gene is fabZ [H]

Identifier: 220932592

GI number: 220932592

Start: 1877355

End: 1877786

Strand: Reverse

Name: fabZ [H]

Synonym: Hore_17560

Alternate gene names: 220932592

Gene position: 1877786-1877355 (Counterclockwise)

Preceding gene: 220932593

Following gene: 220932591

Centisome position: 72.83

GC content: 38.89

Gene sequence:

>432_bases
ATGATGTATATCCAGGATATTAAAAATATACTACCACACCGGTTCCCTTTCTTGCTGGTTGATAGAATTACAGAGTTAGA
GCCTGGTAAAAAAGTAGTTGGTTTTAAAAATGTAACAGTAAATGAAGAATTTTTTCAGGGACATTATCCCGGACATCCAA
TTATGCCTGGTGTCCTTATAATTGAAGCGATGGCCCAGGTGGGTGGCTTTTTAATGATGTATAGTGTTGATGATGATGAG
GAAAAGATTCCTCTCTTTGCCGGGATAGATAAAGCCAGATTTCGGCGCAACGTTGTACCGGGTGACAGATTAAGGATTGA
GGCTGAGGTTATTAAGTTAAGAGGTAGAATCGGCAAGATTGCAGCTAAAGGTTTTGTTGAGGATGAATTAGCAGCTGAGG
CTGAATTAATGTTTGCTATAAATGATAAGTAG

Upstream 100 bases:

>100_bases
TTGTTTCGGGACATATAATAACCGTCAGGTCAGGCCATTCCTTACACGTTGAATTAGCTCAGGAGATTAATAAAAAACTT
ATACAGGAGAGTGAACGAGT

Downstream 100 bases:

>100_bases
AAAGGGGCTTGGTAGGTGTGAAACCTAAGCATGAAGGAAAACTTCTTCATATGGCCAAGATTCATGAGACTGCCATTGTG
CATCCCGGTGCCAAAATCGG

Product: 3-hydroxydecanoyl-(acyl-carrier-protein) dehydratase

Products: NA

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase [H]

Number of amino acids: Translated: 143; Mature: 143

Protein sequence:

>143_residues
MMYIQDIKNILPHRFPFLLVDRITELEPGKKVVGFKNVTVNEEFFQGHYPGHPIMPGVLIIEAMAQVGGFLMMYSVDDDE
EKIPLFAGIDKARFRRNVVPGDRLRIEAEVIKLRGRIGKIAAKGFVEDELAAEAELMFAINDK

Sequences:

>Translated_143_residues
MMYIQDIKNILPHRFPFLLVDRITELEPGKKVVGFKNVTVNEEFFQGHYPGHPIMPGVLIIEAMAQVGGFLMMYSVDDDE
EKIPLFAGIDKARFRRNVVPGDRLRIEAEVIKLRGRIGKIAAKGFVEDELAAEAELMFAINDK
>Mature_143_residues
MMYIQDIKNILPHRFPFLLVDRITELEPGKKVVGFKNVTVNEEFFQGHYPGHPIMPGVLIIEAMAQVGGFLMMYSVDDDE
EKIPLFAGIDKARFRRNVVPGDRLRIEAEVIKLRGRIGKIAAKGFVEDELAAEAELMFAINDK

Specific function: Involved in saturated fatty acids biosynthesis [H]

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786377, Length=139, Percent_Identity=48.9208633093525, Blast_Score=130, Evalue=2e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013114
- InterPro:   IPR010084 [H]

Pfam domain/function: PF07977 FabA [H]

EC number: 4.2.1.-

Molecular weight: Translated: 16217; Mature: 16217

Theoretical pI: Translated: 5.73; Mature: 5.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMYIQDIKNILPHRFPFLLVDRITELEPGKKVVGFKNVTVNEEFFQGHYPGHPIMPGVLI
CCCHHHHHHHCCCCCHHHHHHHHHCCCCCCEEEEEECCEECHHHHCCCCCCCCCCHHHHH
IEAMAQVGGFLMMYSVDDDEEKIPLFAGIDKARFRRNVVPGDRLRIEAEVIKLRGRIGKI
HHHHHHHCCEEEEEEECCCCCCCCEEECCCHHHHHHCCCCCCCEEHHHHHHHHHHHHHHH
AAKGFVEDELAAEAELMFAINDK
HHCCCCHHHHHCCEEEEEEECCC
>Mature Secondary Structure
MMYIQDIKNILPHRFPFLLVDRITELEPGKKVVGFKNVTVNEEFFQGHYPGHPIMPGVLI
CCCHHHHHHHCCCCCHHHHHHHHHCCCCCCEEEEEECCEECHHHHCCCCCCCCCCHHHHH
IEAMAQVGGFLMMYSVDDDEEKIPLFAGIDKARFRRNVVPGDRLRIEAEVIKLRGRIGKI
HHHHHHHCCEEEEEEECCCCCCCCEEECCCHHHHHHCCCCCCCEEHHHHHHHHHHHHHHH
AAKGFVEDELAAEAELMFAINDK
HHCCCCHHHHHCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA