Click here to switch to the map view.

The map label for this gene is 220932536

Identifier: 220932536

GI number: 220932536

Start: 1819089

End: 1820141

Strand: Reverse

Name: 220932536

Synonym: Hore_17000

Alternate gene names: NA

Gene position: 1820141-1819089 (Counterclockwise)

Preceding gene: 220932537

Following gene: 220932535

Centisome position: 70.6

GC content: 32.95

Gene sequence:

>1053_bases
ATGAAACCCTATATCATCGGTGAGACAGCTTATAATCATCAAGGTGACATCCATTATTTAAAAAGAATGATTGATGACAT
TGCTGAAATAGGTCTCCAGGCAGTTAAATTTCATTTGTTATTAAATCCAGAGAGTTATTTACAAAATAAACACCCTTTAA
TTAAAAAAATAAAAGAATGGATTTTTACTGAAAAGGAATGGGATGAGATTATTAATTATTCAAAACAAAAAGGGCTTGAT
ATGATAGCCCTTTGTGATGATTTGGACTCATTAAAATTTATAAAAAAATATCATCGTGACTTGAAGGGAATAGAGATACA
CGCCTCTTCCCTTAATGATTATTTTTTATTAGAAGAAGCCAGAGATTTTCCAAATAGCGTCATCTTAGGAATTGGTGGTT
CAACTCTGGATGAGATTGAGTATGCCGTCAATTTCTTGAAACAAAGAGGCAAAGAAGATATTATATTAATGTATGGTTTT
CAATCCTATCCAACTGATTATACTCAAATTAACCTGGCTAAAATGCAAAAGCTAAAAAATTTATTCAACTTGCCAGTAGG
TTACGCTGATCATACTGCCTATGATGACAAATATAACGTAGATATTTCAGTGATGGCAGCCGCTATGGGAATTAATATCC
TGGAAAAACATTATACCCCTGACTATGGGGTTAAAAGAATAGACTATCATGCCGCGGTGGGTAAAAAGCAAATGAAACAA
ATTAAAGATAAAATGGAGTTGTACCTTACTGTTTTAGGGGATGGATCTCTTTCAATGTCAGACAGTGAATTAAAATATGG
GAATACAGGTCCTATGAAAAAGGCTATTGTAGCCCGTCGTCCCATAAAAAAAGGTGAAAAACTCACCTTTAGTAACCTTT
GTTTTAAAAGAACAGAAGAAGAGTCCCCTGTTCCCCAGAAAATGTTTATTAATTTGCTTGGAATTGAGGCTTACCAGGAT
ATTGATAAAGATGAAATTATAGATTTTTCCAAAGTAAAGTACAGATTTAATAAACAATCATACTCTGATTTAACTGGAGG
ATTGGAGGATTAA

Upstream 100 bases:

>100_bases
AATGAAACAAGAACATGAAAATTTAGTGCAACGATTAGGTAAAAACAAGCAACAGATAAATAAATTGTTGTTTTCCTAGA
ATTCAAGAGGTGGTATATTA

Downstream 100 bases:

>100_bases
TACGTGAAAATAGGTTTTCTAATAACAGCCCGTTTAAAATCAAGCAGGTTACCGTTTAAAATTTTAAAGGACTTAAATGG
TAAAAAGGTCATTGAACGTA

Product: N-acetylneuraminate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 350; Mature: 350

Protein sequence:

>350_residues
MKPYIIGETAYNHQGDIHYLKRMIDDIAEIGLQAVKFHLLLNPESYLQNKHPLIKKIKEWIFTEKEWDEIINYSKQKGLD
MIALCDDLDSLKFIKKYHRDLKGIEIHASSLNDYFLLEEARDFPNSVILGIGGSTLDEIEYAVNFLKQRGKEDIILMYGF
QSYPTDYTQINLAKMQKLKNLFNLPVGYADHTAYDDKYNVDISVMAAAMGINILEKHYTPDYGVKRIDYHAAVGKKQMKQ
IKDKMELYLTVLGDGSLSMSDSELKYGNTGPMKKAIVARRPIKKGEKLTFSNLCFKRTEEESPVPQKMFINLLGIEAYQD
IDKDEIIDFSKVKYRFNKQSYSDLTGGLED

Sequences:

>Translated_350_residues
MKPYIIGETAYNHQGDIHYLKRMIDDIAEIGLQAVKFHLLLNPESYLQNKHPLIKKIKEWIFTEKEWDEIINYSKQKGLD
MIALCDDLDSLKFIKKYHRDLKGIEIHASSLNDYFLLEEARDFPNSVILGIGGSTLDEIEYAVNFLKQRGKEDIILMYGF
QSYPTDYTQINLAKMQKLKNLFNLPVGYADHTAYDDKYNVDISVMAAAMGINILEKHYTPDYGVKRIDYHAAVGKKQMKQ
IKDKMELYLTVLGDGSLSMSDSELKYGNTGPMKKAIVARRPIKKGEKLTFSNLCFKRTEEESPVPQKMFINLLGIEAYQD
IDKDEIIDFSKVKYRFNKQSYSDLTGGLED
>Mature_350_residues
MKPYIIGETAYNHQGDIHYLKRMIDDIAEIGLQAVKFHLLLNPESYLQNKHPLIKKIKEWIFTEKEWDEIINYSKQKGLD
MIALCDDLDSLKFIKKYHRDLKGIEIHASSLNDYFLLEEARDFPNSVILGIGGSTLDEIEYAVNFLKQRGKEDIILMYGF
QSYPTDYTQINLAKMQKLKNLFNLPVGYADHTAYDDKYNVDISVMAAAMGINILEKHYTPDYGVKRIDYHAAVGKKQMKQ
IKDKMELYLTVLGDGSLSMSDSELKYGNTGPMKKAIVARRPIKKGEKLTFSNLCFKRTEEESPVPQKMFINLLGIEAYQD
IDKDEIIDFSKVKYRFNKQSYSDLTGGLED

Specific function: Unknown

COG id: COG2089

COG function: function code M; Sialic acid synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To B.subtilis spsE [H]

Homologues:

Organism=Homo sapiens, GI12056473, Length=337, Percent_Identity=23.7388724035608, Blast_Score=89, Evalue=5e-18,
Organism=Drosophila melanogaster, GI21357081, Length=360, Percent_Identity=26.3888888888889, Blast_Score=110, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006190
- InterPro:   IPR013785
- InterPro:   IPR013132
- InterPro:   IPR013974 [H]

Pfam domain/function: PF03102 NeuB; PF08666 SAF [H]

EC number: NA

Molecular weight: Translated: 40380; Mature: 40380

Theoretical pI: Translated: 6.61; Mature: 6.61

Prosite motif: PS50844 AFP_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPYIIGETAYNHQGDIHYLKRMIDDIAEIGLQAVKFHLLLNPESYLQNKHPLIKKIKEW
CCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHEEEEEEECCHHHHCCCCHHHHHHHHH
IFTEKEWDEIINYSKQKGLDMIALCDDLDSLKFIKKYHRDLKGIEIHASSLNDYFLLEEA
HCCCHHHHHHHCCHHHCCCEEEEECCCHHHHHHHHHHHHCCCCEEEEECCCCCEEEEHHH
RDFPNSVILGIGGSTLDEIEYAVNFLKQRGKEDIILMYGFQSYPTDYTQINLAKMQKLKN
HCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCEEHHHHHHHHHH
LFNLPVGYADHTAYDDKYNVDISVMAAAMGINILEKHYTPDYGVKRIDYHAAVGKKQMKQ
HHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHCHHHHHH
IKDKMELYLTVLGDGSLSMSDSELKYGNTGPMKKAIVARRPIKKGEKLTFSNLCFKRTEE
HHHHHHEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCEEHHHHHHHCCCC
ESPVPQKMFINLLGIEAYQDIDKDEIIDFSKVKYRFNKQSYSDLTGGLED
CCCCCHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHCCCHHHHHCCCCCC
>Mature Secondary Structure
MKPYIIGETAYNHQGDIHYLKRMIDDIAEIGLQAVKFHLLLNPESYLQNKHPLIKKIKEW
CCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHEEEEEEECCHHHHCCCCHHHHHHHHH
IFTEKEWDEIINYSKQKGLDMIALCDDLDSLKFIKKYHRDLKGIEIHASSLNDYFLLEEA
HCCCHHHHHHHCCHHHCCCEEEEECCCHHHHHHHHHHHHCCCCEEEEECCCCCEEEEHHH
RDFPNSVILGIGGSTLDEIEYAVNFLKQRGKEDIILMYGFQSYPTDYTQINLAKMQKLKN
HCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCEEHHHHHHHHHH
LFNLPVGYADHTAYDDKYNVDISVMAAAMGINILEKHYTPDYGVKRIDYHAAVGKKQMKQ
HHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHCHHHHHH
IKDKMELYLTVLGDGSLSMSDSELKYGNTGPMKKAIVARRPIKKGEKLTFSNLCFKRTEE
HHHHHHEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCEEHHHHHHHCCCC
ESPVPQKMFINLLGIEAYQDIDKDEIIDFSKVKYRFNKQSYSDLTGGLED
CCCCCHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHCCCHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]