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The map label for this gene is secA

Identifier: 220932480

GI number: 220932480

Start: 1766491

End: 1769028

Strand: Reverse

Name: secA

Synonym: Hore_16440

Alternate gene names: 220932480

Gene position: 1769028-1766491 (Counterclockwise)

Preceding gene: 220932481

Following gene: 220932479

Centisome position: 68.62

GC content: 41.65

Gene sequence:

>2538_bases
TTGTTAAAATTTATAAAAAATATCTTTAAAGATTCAAATACCCGGGAACTGGAAAAATTACAGCACATTGTTGATGAGAT
TAACAGTCTTGAACCCTATATGAAGAAGCTTTCAGATGAGCAATTGAGGGATAAAACCAGAGAATTTAAGGAACGGATTG
TAAAAGGTGAAACCCTTGATGAATTATTACCGGAAGCCTTTGCTGTAGTCCGGGAAGCGGCCCAGAGGTCTACTTCAGAA
AAATTCAGACACTATGATGTCCAGCTTATGGGTGGTATTGTGTTACACCAGGGTAAAATTGCCGAAATGAAAACCGGTGA
GGGGAAAACCCTGGCTGCCACTTTGCCGGTATATCTCAATGCCCTGACCGGTAAAGGTGTTCATGTGGTTACTGTTAATG
ACTATCTTGCTAAAAGGGATAGTGAATGGATGGGACAAATATACCGGTTTTTAGGCCTGTCTGTTGGTGTTATTTTAAAC
GGGATGACTCCCCGGGAAAGAAAAAAGGCCTACCAGGCAGATGTAACCTATGGTTCCAATAATGAATTTGGGTTTGACTA
TCTCCGTGATAACCTGGCCTATAATCCTGATGATGTCGTACAGGGGGAACTACATTATGCCATTCTTGATGAAGTTGATA
GTATTCTAATAGATGAAGCCAGGACCCCCCTTATTATTTCAGGGCCGGCTCAGGAGACAACTAAAGATTACCGGAAGTTT
AACCGGATTATCCCCAGGCTTGTAAAAGGTAGGGACTATGAGGTTGATGAGAAAAACAGGACCGTCCATTTAACAGAAGA
GGGCCTGGCCCGGGTGGAAAAAAAGTTAAATATCTCAAACCTCTATGATGATCAAAACTTCCAGCTTGCCCATCAGCTAA
ATCAGGCCTTAAAGGCCCATACCCTGATGAAAAAAGACCGGGATTATATTGTTAAAGATGGAGAAGTTAAAATTGTAGAT
GAATTTACCGGACGAATTATGGAAGGCAGGAGGTTTAGTGAAGGGCTCCACCAGGCCATAGAGGCTAAAGAGGGTGTTGC
CGTCAATAAGGAAAGCCAGACGTTTGCCAGTATAACCTATCAGAATTTTTTCAGAATGTATGATAAACTGGCCGGTATGA
CCGGTACGGCAGCCACTGAAGAAGAAGAGTTTATTAAAATCTATGGCATGGAAGTTGTCCAGATACCTACCAATAAACCA
ATGATCAGGGAGGACCTTCCTGATGTTGTATTCAGGACCGAGGAGGCCAAGTTTAAAGCTGTTGCTGAAGAAGTAGCCCT
TAAATATAAAAAAGGACAACCGGTCCTGGTCGGTACTGTTGATATCGAAAAATCGGAAAAGTTAAGTAGAATGCTGAAGA
GAAAAGGTATTCCCCACCAGGTCCTGAATGCCAAGAACCATGAAAAGGAAGCAGAAATTATTAAAAAGGCCGGTCAAAAG
AATAGTGTTACCATTTCTACAAATATGGCCGGGCGTGGTACGGATATTGTGCTCGGTGAAGGTGTAAAAGAATTGGGAGG
ACTCCATGTCATCGGAACCGAAAGACATGAAAGCCGCCGTATCGATAACCAGTTGCGGGGGCGTTCCGGAAGGCAGGGAG
ATCCCGGTTCATCCCAGTTTTTCGTATCACTGGAGGATGACCTCCTGAGATTGTTTGGCTCTGATAATATAAGTATGTTA
ATGGACCGGATGGGATTTGATGATGACCAGCCCATTGAGCATAAAATGATAACAAGATCCCTGGAAAGGGCCCAGAAAAA
GGTCGAAGGAAGAAATTTCGAAATACGTAAGACCATCCTTGAATATGATAATATTATGAATAAACAGCGGGAAATAATCT
ATGAGCAGAGGAAGAAAATCCTCTTTGCATCTGACCTCAAGGAGTATATAATGGGTATGATAGAAATGCTGGTTGATGAT
ATTATGGATACCTATCTTTCCAGTGAGGTCCATCCCGATGACTGGGATATAGACGGTCTGATTAAATACCTGTCTGAATT
TAATCTGGTCAATATTAATGAAGAGGACTTCAAGGATAAGGATCGGGAAAAAATAAGAGAAGAATTAATTAAAATTGCCA
CAAAAACCTATGAAGAAAAAGAAGCTGAGATAGGTAAGGAGTCCATGCAAAAGCTGATCAAGAACCTGGCCCTCAGAATC
ATTGACCGGAACTGGATGAATCACCTGGATAATATGGATGAATTGAGACAGGGTATTGGTTTAAGGGCATATGGCCAGCG
GGACCCGTTAACAGAATATAAATTTGAATCCTATGATATGTTTAATGGTATGACGGGAACTATCAGGGAAGAGATAATTA
AAAACTTATTCCGGATTGAAGTAAAGGAACGGGAAATAAATTTAGATCCCATTATGTTAAAGAGGTTGAAATACCGCCGT
AACTTTTTATCAAACCGGGCAAACAGGCCCCAAAAGAAGGCTAAAAGACAGCCCATTGTAAAACCTGATAAACCTGGGAG
AAATGATCCCTGCCCCTGTGGTAGTGGCAAAAAGTATAAACACTGTTGTGGGAGGTAA

Upstream 100 bases:

>100_bases
TGACAAAAATGGTGTTATAATAAAATCTAGAGAATTTTAAAATGTCAGGGAATTTTTACCCTGGCATTATTTTTAGGTTG
AAAAAGAAAAGGTGGTCAAA

Downstream 100 bases:

>100_bases
TAAAATATGTTAAAAGATATGAACTATACCCAGAAACTGGAGAACCTGTCCCGGAGGATTTCAGATTTGAGGGATTACCT
TTGACTGGGATAATCTCCTT

Product: preprotein translocase subunit SecA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 845; Mature: 845

Protein sequence:

>845_residues
MLKFIKNIFKDSNTRELEKLQHIVDEINSLEPYMKKLSDEQLRDKTREFKERIVKGETLDELLPEAFAVVREAAQRSTSE
KFRHYDVQLMGGIVLHQGKIAEMKTGEGKTLAATLPVYLNALTGKGVHVVTVNDYLAKRDSEWMGQIYRFLGLSVGVILN
GMTPRERKKAYQADVTYGSNNEFGFDYLRDNLAYNPDDVVQGELHYAILDEVDSILIDEARTPLIISGPAQETTKDYRKF
NRIIPRLVKGRDYEVDEKNRTVHLTEEGLARVEKKLNISNLYDDQNFQLAHQLNQALKAHTLMKKDRDYIVKDGEVKIVD
EFTGRIMEGRRFSEGLHQAIEAKEGVAVNKESQTFASITYQNFFRMYDKLAGMTGTAATEEEEFIKIYGMEVVQIPTNKP
MIREDLPDVVFRTEEAKFKAVAEEVALKYKKGQPVLVGTVDIEKSEKLSRMLKRKGIPHQVLNAKNHEKEAEIIKKAGQK
NSVTISTNMAGRGTDIVLGEGVKELGGLHVIGTERHESRRIDNQLRGRSGRQGDPGSSQFFVSLEDDLLRLFGSDNISML
MDRMGFDDDQPIEHKMITRSLERAQKKVEGRNFEIRKTILEYDNIMNKQREIIYEQRKKILFASDLKEYIMGMIEMLVDD
IMDTYLSSEVHPDDWDIDGLIKYLSEFNLVNINEEDFKDKDREKIREELIKIATKTYEEKEAEIGKESMQKLIKNLALRI
IDRNWMNHLDNMDELRQGIGLRAYGQRDPLTEYKFESYDMFNGMTGTIREEIIKNLFRIEVKEREINLDPIMLKRLKYRR
NFLSNRANRPQKKAKRQPIVKPDKPGRNDPCPCGSGKKYKHCCGR

Sequences:

>Translated_845_residues
MLKFIKNIFKDSNTRELEKLQHIVDEINSLEPYMKKLSDEQLRDKTREFKERIVKGETLDELLPEAFAVVREAAQRSTSE
KFRHYDVQLMGGIVLHQGKIAEMKTGEGKTLAATLPVYLNALTGKGVHVVTVNDYLAKRDSEWMGQIYRFLGLSVGVILN
GMTPRERKKAYQADVTYGSNNEFGFDYLRDNLAYNPDDVVQGELHYAILDEVDSILIDEARTPLIISGPAQETTKDYRKF
NRIIPRLVKGRDYEVDEKNRTVHLTEEGLARVEKKLNISNLYDDQNFQLAHQLNQALKAHTLMKKDRDYIVKDGEVKIVD
EFTGRIMEGRRFSEGLHQAIEAKEGVAVNKESQTFASITYQNFFRMYDKLAGMTGTAATEEEEFIKIYGMEVVQIPTNKP
MIREDLPDVVFRTEEAKFKAVAEEVALKYKKGQPVLVGTVDIEKSEKLSRMLKRKGIPHQVLNAKNHEKEAEIIKKAGQK
NSVTISTNMAGRGTDIVLGEGVKELGGLHVIGTERHESRRIDNQLRGRSGRQGDPGSSQFFVSLEDDLLRLFGSDNISML
MDRMGFDDDQPIEHKMITRSLERAQKKVEGRNFEIRKTILEYDNIMNKQREIIYEQRKKILFASDLKEYIMGMIEMLVDD
IMDTYLSSEVHPDDWDIDGLIKYLSEFNLVNINEEDFKDKDREKIREELIKIATKTYEEKEAEIGKESMQKLIKNLALRI
IDRNWMNHLDNMDELRQGIGLRAYGQRDPLTEYKFESYDMFNGMTGTIREEIIKNLFRIEVKEREINLDPIMLKRLKYRR
NFLSNRANRPQKKAKRQPIVKPDKPGRNDPCPCGSGKKYKHCCGR
>Mature_845_residues
MLKFIKNIFKDSNTRELEKLQHIVDEINSLEPYMKKLSDEQLRDKTREFKERIVKGETLDELLPEAFAVVREAAQRSTSE
KFRHYDVQLMGGIVLHQGKIAEMKTGEGKTLAATLPVYLNALTGKGVHVVTVNDYLAKRDSEWMGQIYRFLGLSVGVILN
GMTPRERKKAYQADVTYGSNNEFGFDYLRDNLAYNPDDVVQGELHYAILDEVDSILIDEARTPLIISGPAQETTKDYRKF
NRIIPRLVKGRDYEVDEKNRTVHLTEEGLARVEKKLNISNLYDDQNFQLAHQLNQALKAHTLMKKDRDYIVKDGEVKIVD
EFTGRIMEGRRFSEGLHQAIEAKEGVAVNKESQTFASITYQNFFRMYDKLAGMTGTAATEEEEFIKIYGMEVVQIPTNKP
MIREDLPDVVFRTEEAKFKAVAEEVALKYKKGQPVLVGTVDIEKSEKLSRMLKRKGIPHQVLNAKNHEKEAEIIKKAGQK
NSVTISTNMAGRGTDIVLGEGVKELGGLHVIGTERHESRRIDNQLRGRSGRQGDPGSSQFFVSLEDDLLRLFGSDNISML
MDRMGFDDDQPIEHKMITRSLERAQKKVEGRNFEIRKTILEYDNIMNKQREIIYEQRKKILFASDLKEYIMGMIEMLVDD
IMDTYLSSEVHPDDWDIDGLIKYLSEFNLVNINEEDFKDKDREKIREELIKIATKTYEEKEAEIGKESMQKLIKNLALRI
IDRNWMNHLDNMDELRQGIGLRAYGQRDPLTEYKFESYDMFNGMTGTIREEIIKNLFRIEVKEREINLDPIMLKRLKYRR
NFLSNRANRPQKKAKRQPIVKPDKPGRNDPCPCGSGKKYKHCCGR

Specific function: Part of the Sec protein translocase complex. Interacts with the secYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular mo

COG id: COG0653

COG function: function code U; Preprotein translocase subunit SecA (ATPase, RNA helicase)

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm (By similarity). Note=Distribution is 50-50 (By similarity)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secA family

Homologues:

Organism=Escherichia coli, GI1786287, Length=901, Percent_Identity=49.8335183129856, Blast_Score=870, Evalue=0.0,
Organism=Escherichia coli, GI1788219, Length=74, Percent_Identity=43.2432432432432, Blast_Score=68, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SECA_HALOH (B8CYM4)

Other databases:

- EMBL:   CP001098
- RefSeq:   YP_002509388.1
- GeneID:   7313161
- GenomeReviews:   CP001098_GR
- KEGG:   hor:Hore_16440
- HOGENOM:   HBG284200
- OMA:   GGMVLHD
- ProtClustDB:   CLSK2806498
- GO:   GO:0005737
- HAMAP:   MF_01382
- InterPro:   IPR004027
- InterPro:   IPR000185
- InterPro:   IPR020937
- InterPro:   IPR011115
- InterPro:   IPR014018
- InterPro:   IPR011130
- InterPro:   IPR011116
- Gene3D:   G3DSA:1.10.3060.10
- PRINTS:   PR00906
- SMART:   SM00957
- SMART:   SM00958
- TIGRFAMs:   TIGR00963

Pfam domain/function: PF02810 SEC-C; PF07517 SecA_DEAD; PF01043 SecA_PP_bind; PF07516 SecA_SW; SSF81767 SecA_PP_bd; SSF81886 SecA_SW

EC number: NA

Molecular weight: Translated: 97673; Mature: 97673

Theoretical pI: Translated: 7.51; Mature: 7.51

Prosite motif: PS01312 SECA; PS51196 SECA_MOTOR_DEAD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKFIKNIFKDSNTRELEKLQHIVDEINSLEPYMKKLSDEQLRDKTREFKERIVKGETLD
CHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCHH
ELLPEAFAVVREAAQRSTSEKFRHYDVQLMGGIVLHQGKIAEMKTGEGKTLAATLPVYLN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCCCEEEEEHHHHHH
ALTGKGVHVVTVNDYLAKRDSEWMGQIYRFLGLSVGVILNGMTPRERKKAYQADVTYGSN
HHCCCCEEEEEECHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCEECCC
NEFGFDYLRDNLAYNPDDVVQGELHYAILDEVDSILIDEARTPLIISGPAQETTKDYRKF
CCCCHHHHHHCCCCCCCHHHCCHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHH
NRIIPRLVKGRDYEVDEKNRTVHLTEEGLARVEKKLNISNLYDDQNFQLAHQLNQALKAH
HHHHHHHHCCCCCCCCCCCCEEEECHHHHHHHHHHCCHHHCCCCCCHHHHHHHHHHHHHH
TLMKKDRDYIVKDGEVKIVDEFTGRIMEGRRFSEGLHQAIEAKEGVAVNKESQTFASITY
HHHHCCCCCEEECCCEEEEHHHHHHHHCCCHHHHHHHHHHHHHCCCEECCCCHHHHHHHH
QNFFRMYDKLAGMTGTAATEEEEFIKIYGMEVVQIPTNKPMIREDLPDVVFRTEEAKFKA
HHHHHHHHHHCCCCCCCCCCHHHHHHEECCEEEEECCCCCHHHHCCHHHHEECCHHHHHH
VAEEVALKYKKGQPVLVGTVDIEKSEKLSRMLKRKGIPHQVLNAKNHEKEAEIIKKAGQK
HHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHCCCCHHHHCCCCCHHHHHHHHHCCCC
NSVTISTNMAGRGTDIVLGEGVKELGGLHVIGTERHESRRIDNQLRGRSGRQGDPGSSQF
CCEEEEECCCCCCCEEEECCCHHHHCCEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCEE
FVSLEDDLLRLFGSDNISMLMDRMGFDDDQPIEHKMITRSLERAQKKVEGRNFEIRKTIL
EEEEHHHHHHHHCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
EYDNIMNKQREIIYEQRKKILFASDLKEYIMGMIEMLVDDIMDTYLSSEVHPDDWDIDGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHH
IKYLSEFNLVNINEEDFKDKDREKIREELIKIATKTYEEKEAEIGKESMQKLIKNLALRI
HHHHHCCCEECCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
IDRNWMNHLDNMDELRQGIGLRAYGQRDPLTEYKFESYDMFNGMTGTIREEIIKNLFRIE
HHHHHHHHHCCHHHHHHCCCCEECCCCCCCCCCCCCCHHHCCCCCHHHHHHHHHHHHHEE
VKEREINLDPIMLKRLKYRRNFLSNRANRPQKKAKRQPIVKPDKPGRNDPCPCGSGKKYK
HHHCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCHH
HCCGR
HHCCC
>Mature Secondary Structure
MLKFIKNIFKDSNTRELEKLQHIVDEINSLEPYMKKLSDEQLRDKTREFKERIVKGETLD
CHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCHH
ELLPEAFAVVREAAQRSTSEKFRHYDVQLMGGIVLHQGKIAEMKTGEGKTLAATLPVYLN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCCCEEEEEHHHHHH
ALTGKGVHVVTVNDYLAKRDSEWMGQIYRFLGLSVGVILNGMTPRERKKAYQADVTYGSN
HHCCCCEEEEEECHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCEECCC
NEFGFDYLRDNLAYNPDDVVQGELHYAILDEVDSILIDEARTPLIISGPAQETTKDYRKF
CCCCHHHHHHCCCCCCCHHHCCHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHH
NRIIPRLVKGRDYEVDEKNRTVHLTEEGLARVEKKLNISNLYDDQNFQLAHQLNQALKAH
HHHHHHHHCCCCCCCCCCCCEEEECHHHHHHHHHHCCHHHCCCCCCHHHHHHHHHHHHHH
TLMKKDRDYIVKDGEVKIVDEFTGRIMEGRRFSEGLHQAIEAKEGVAVNKESQTFASITY
HHHHCCCCCEEECCCEEEEHHHHHHHHCCCHHHHHHHHHHHHHCCCEECCCCHHHHHHHH
QNFFRMYDKLAGMTGTAATEEEEFIKIYGMEVVQIPTNKPMIREDLPDVVFRTEEAKFKA
HHHHHHHHHHCCCCCCCCCCHHHHHHEECCEEEEECCCCCHHHHCCHHHHEECCHHHHHH
VAEEVALKYKKGQPVLVGTVDIEKSEKLSRMLKRKGIPHQVLNAKNHEKEAEIIKKAGQK
HHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHCCCCHHHHCCCCCHHHHHHHHHCCCC
NSVTISTNMAGRGTDIVLGEGVKELGGLHVIGTERHESRRIDNQLRGRSGRQGDPGSSQF
CCEEEEECCCCCCCEEEECCCHHHHCCEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCEE
FVSLEDDLLRLFGSDNISMLMDRMGFDDDQPIEHKMITRSLERAQKKVEGRNFEIRKTIL
EEEEHHHHHHHHCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
EYDNIMNKQREIIYEQRKKILFASDLKEYIMGMIEMLVDDIMDTYLSSEVHPDDWDIDGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHH
IKYLSEFNLVNINEEDFKDKDREKIREELIKIATKTYEEKEAEIGKESMQKLIKNLALRI
HHHHHCCCEECCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
IDRNWMNHLDNMDELRQGIGLRAYGQRDPLTEYKFESYDMFNGMTGTIREEIIKNLFRIE
HHHHHHHHHCCHHHHHHCCCCEECCCCCCCCCCCCCCHHHCCCCCHHHHHHHHHHHHHEE
VKEREINLDPIMLKRLKYRRNFLSNRANRPQKKAKRQPIVKPDKPGRNDPCPCGSGKKYK
HHHCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCHH
HCCGR
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA