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The map label for this gene is kynB [H]

Identifier: 220932462

GI number: 220932462

Start: 1747586

End: 1748164

Strand: Reverse

Name: kynB [H]

Synonym: Hore_16260

Alternate gene names: 220932462

Gene position: 1748164-1747586 (Counterclockwise)

Preceding gene: 220932463

Following gene: 220932461

Centisome position: 67.81

GC content: 39.21

Gene sequence:

>579_bases
ATGAAGCCGGTCTTTAGCGTGGTCCAGGACTTTTTGTCCTCTGATGTTCATCAGACTAAAGTAACCCTTGACCTTCATAC
CGGAACCCACCTCGATACCCCCCTCCATATGATAGAAAACGGGGATGATATAGAGTATTTTAACCTTGAAGATGTTATTT
CAAAATGTACTGTTCTGGATCTGACCGGTGTTGATGATAAGATTACTGAAACCCATTTATCAGGTAAAAATATTAGTAGT
AATGAGTTTGTTTTATTAAAGACCGAGAATTCTACCCGGGATGATTTTACGACTGATTTTGTTTTCCTAAGTGAAACCGG
GGCAGAATATCTGGCCCGTCAGAATATCACGGGAGTGGGGATTGACTCCCTGGGAATTGAGCGGAATCAACCAGGTCATC
CCACCCATAAAATTTTATTATCAAAAGGAATTTATATCATAGAAGGCCTTAGACTGGAGGATGTACCTGAGGGTAATTAT
TATCTTCTTATGGTTCCTTTAAATATAAAACATGCAGATGGTGTTCCGGTCCGGGTATTGCTAATTGATGAGTTAAAGTC
ATTTATTAATAGTCTTTAG

Upstream 100 bases:

>100_bases
AAGCTAACTATGTTAATTATATGGGGTGATTAAAGTGAAAATATATGATATTTCCATGCCTGTCCACTCCGGAATGCCAG
TTTATAAAAATAGGGAGGAG

Downstream 100 bases:

>100_bases
TCCATTTATAAATAAACTTTAGCCACTTAGACAAAAAGATTAAAGTAAATAACTATACCCCACCCGGTATGGTTATAATA
TATGTCGTTTCAGTATTTTA

Product: cyclase family protein

Products: NA

Alternate protein names: KFA; N-formylkynurenine formamidase [H]

Number of amino acids: Translated: 192; Mature: 192

Protein sequence:

>192_residues
MKPVFSVVQDFLSSDVHQTKVTLDLHTGTHLDTPLHMIENGDDIEYFNLEDVISKCTVLDLTGVDDKITETHLSGKNISS
NEFVLLKTENSTRDDFTTDFVFLSETGAEYLARQNITGVGIDSLGIERNQPGHPTHKILLSKGIYIIEGLRLEDVPEGNY
YLLMVPLNIKHADGVPVRVLLIDELKSFINSL

Sequences:

>Translated_192_residues
MKPVFSVVQDFLSSDVHQTKVTLDLHTGTHLDTPLHMIENGDDIEYFNLEDVISKCTVLDLTGVDDKITETHLSGKNISS
NEFVLLKTENSTRDDFTTDFVFLSETGAEYLARQNITGVGIDSLGIERNQPGHPTHKILLSKGIYIIEGLRLEDVPEGNY
YLLMVPLNIKHADGVPVRVLLIDELKSFINSL
>Mature_192_residues
MKPVFSVVQDFLSSDVHQTKVTLDLHTGTHLDTPLHMIENGDDIEYFNLEDVISKCTVLDLTGVDDKITETHLSGKNISS
NEFVLLKTENSTRDDFTTDFVFLSETGAEYLARQNITGVGIDSLGIERNQPGHPTHKILLSKGIYIIEGLRLEDVPEGNY
YLLMVPLNIKHADGVPVRVLLIDELKSFINSL

Specific function: Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine [H]

COG id: COG1878

COG function: function code R; Predicted metal-dependent hydrolase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kynB family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017484
- InterPro:   IPR007325 [H]

Pfam domain/function: PF04199 Cyclase [H]

EC number: =3.5.1.9 [H]

Molecular weight: Translated: 21454; Mature: 21454

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPVFSVVQDFLSSDVHQTKVTLDLHTGTHLDTPLHMIENGDDIEYFNLEDVISKCTVLD
CCHHHHHHHHHHCCCCEEEEEEEEEECCCCCCCCHHHHCCCCCEEEECHHHHHHHCEEEE
LTGVDDKITETHLSGKNISSNEFVLLKTENSTRDDFTTDFVFLSETGAEYLARQNITGVG
ECCCCCHHHHHCCCCCCCCCCCEEEEECCCCCCCCCCEEEEEEECCCHHHHHHCCCCCCC
IDSLGIERNQPGHPTHKILLSKGIYIIEGLRLEDVPEGNYYLLMVPLNIKHADGVPVRVL
CCCCCCCCCCCCCCHHHHHHHCCEEEEECCEEECCCCCCEEEEEEEEEEECCCCCCEEEE
LIDELKSFINSL
EHHHHHHHHHCC
>Mature Secondary Structure
MKPVFSVVQDFLSSDVHQTKVTLDLHTGTHLDTPLHMIENGDDIEYFNLEDVISKCTVLD
CCHHHHHHHHHHCCCCEEEEEEEEEECCCCCCCCHHHHCCCCCEEEECHHHHHHHCEEEE
LTGVDDKITETHLSGKNISSNEFVLLKTENSTRDDFTTDFVFLSETGAEYLARQNITGVG
ECCCCCHHHHHCCCCCCCCCCCEEEEECCCCCCCCCCEEEEEEECCCHHHHHHCCCCCCC
IDSLGIERNQPGHPTHKILLSKGIYIIEGLRLEDVPEGNYYLLMVPLNIKHADGVPVRVL
CCCCCCCCCCCCCCHHHHHHHCCEEEEECCEEECCCCCCEEEEEEEEEEECCCCCCEEEE
LIDELKSFINSL
EHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA