| Definition | Halothermothrix orenii H 168 chromosome, complete genome. |
|---|---|
| Accession | NC_011899 |
| Length | 2,578,146 |
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The map label for this gene is uvrA [H]
Identifier: 220932458
GI number: 220932458
Start: 1740648
End: 1743473
Strand: Reverse
Name: uvrA [H]
Synonym: Hore_16220
Alternate gene names: 220932458
Gene position: 1743473-1740648 (Counterclockwise)
Preceding gene: 220932459
Following gene: 220932457
Centisome position: 67.63
GC content: 45.33
Gene sequence:
>2826_bases ATGGTCAAGGAAATGATTTATGTTAAGGGAGCCCAGGAGCATAATTTAAAGAATATTGATGTCAGGATTCCAAGGGATAA ACTTATAGTTATAACCGGTTTGAGTGGTTCTGGTAAATCTTCACTGGCTTTTGATACCATTTATGCTGAGGGTCAAAGGC GTTATGTCGAGTCTCTATCAGCCTATGCCCGGCAGTTTTTAGGACAGATGGAAAAACCCCGGGTTGAATATATAGAAGGT TTATCTCCTGCTATTTCAATTGATCAGAAAACCACCAGTAAAAACCCCCGTTCCACAGTCGGTACTGTTACTGAAATCTA TGACTATCTGCGCCTTCTGTATGCCAGAATAGGAAGGCCCCACTGCCCCGAATGCGGGCGGGCTATCTCATCCCAGAGTG TTGATGAGATAGTGGATCAGGTTCTGGATCTACCGGGAAGGACCAAAATACAGATTCTGTCACCGGTGGTCAGGGGAAGA AAGGGTGAGCATCAGAAGGTATTTACAAGGGCCCTGAGGGATGGTTTTGTCAGGGCCCGGGTAGATGGAAGGGTCATCAT TCTGGGGGAAGAAGAGGTTAGCCTTGAGAAAAATTTAAAACATGATATTGAAGTTGTCGTCGATAGACTGGTTATTAAAG AAGGTATCCGGGAGCGATTGACCGATTCCATTGAGACTGCCCTGGAATACAGTGAAGGGCTGGTCATTGTAGATGTTATC GATGGAGATGAAATGGTATTTAGTGAGAAATTTGCCTGTCCCGAATGTGGTATCAGTCTGGAAGAAATGTCTCCCCGGAT GTTTTCTTTCAACAGCCCCTATGGGGCCTGTCCCAATTGTGATGGACTGGGTATAAAAAAGGAATTTGATCCTGATCTTA TCCTTGATAAGGAAAAATCCATCAGTAACGGGGCCATTATTCCCTGGCGTAATTCAACAAGTCGTTATTATCCTCAGCTC CTGTCAGCCCTGGCTGAAGAGTATAACTTCAGCCTGGATACCCCCCTGGAGCAACTGGATGATGACATCATAGATATTAT TCTGTACGGTTCGGACAGGCAACTTGTTTTTCCCTATACCAACCGCTATGGGAGAACCAGGCAGCATAAAACCTATTTTA AGGGGATAGTTGGTTATTTAAAAAGGCGGGTTAATGAATCTGACTCTCCGACAGCCCATCGCAGGCTGGAAAGATATATG AGTGAACGGCCCTGTTCTACCTGTCAGGGGGGCCGGTTGCGGCCTGAGGTTCTGGCTGTGACGGTCGGGGGTAAATCAAT TGCCGAATTTACCCGTTATTCAATTAAGGAAGCCTATGATTTCATAGAAGAATTAAATTTAACAGAAAGGGAACAGTATA TAAGTCAGGAAATTATTAAAGAGATTAAAAACAGGTTACGGTTTTTAATAGATGTTGGTCTGGACTATCTTACCCTGGAC CGGCCGGCCGGGAGTTTGTCCGGGGGTGAGGCCCAGCGAATCAGGCTGGCTACCCAGATTGGTTCAGGACTGGTAGGGGT TTTATATATTCTAGATGAACCGAGTATAGGGCTCCACCAGAGGGATAATAACCGTTTAATAAGAACCCTTGAACATATCA GGGATCTGGGGAATACGGTTATTGTTGTTGAACATGATGAAGATACCATCAGGGCAGCTGACCACATTATTGACATCGGT CCCAGGGCCGGTAAACACGGTGGCCGGGTGGTAGCCCAGGGTTCTCTGGAAGACATTGTTTCCAGTAAAGAATCCCTGAC CGGTCAGTATTTATCTGGAGAAAAGAAAATACCGGTACCTGAAAAGAGGGTTAGACCCAATGGTAAATACCTGGAGATTA AGGGGGCCAGGCAGCATAACCTTAAAAATATAGATGTCAAAATCCCCCTGGGGACTTTTACCTGTGTTACCGGTGTTTCC GGTTCAGGGAAGAGTACCCTGATTAATTTGACTTTGAAACGAAAGTTAATGCAGCATTTTTATGATTCCACCCTGAGGCC GGGTGAACATGATGAAATAAAGGGGCTGGAGTATGTCGATAAGATTATTAATATAGACCAGTCACCCATAGGCAGGACCC CTAGGTCAAATCCAGCAACCTACACCAAGGTTTTTGATTATATCCGGGATGTGTTTGCCAAAACCCCCGAGGCCCGGAGG ATGGGGTATAAGAAGGGGAGGTTCAGTTTTAACGTAAAAGGGGGCCGTTGTGAGGCCTGTAAAGGTGATGGCATAATCAA GATAGAAATGCATTTTCTGCCTGATGTTTATGTCCCCTGTGAGGTATGCGGGGGTAAAAGATATAACCGGGAGACCCTGG AGATAAAATATAAGGGAAAAACAATAGCAGATATACTCGAGATGACGGTTGAGGAAGCCCTGGAGTTTTTTGCCAATGTC AATCCGATAAAGAGGCGGTTACAGACCCTTTATGATGTTGGTCTCGGTTATATTCGACTGGGTCAACCGGCAACAACTTT ATCCGGGGGTGAGGCCCAGAGGATAAAGATTGCCTCTGAACTGGGAAAAAGGAGTACCGGAAAGACCATCTATATTCTGG ATGAACCAACTACCGGTCTGCATTTTGAGGATGTAAAGAAACTTCTTGAAGTACTCTTCAGACTCCGGGAAGGTGGTAAT ACCGTCATTGTAATAGAGCATAACCTTGATGTTATAAAAGCTGCCGATTATATCATAGACCTTGGCCCTGAAGGAGGGGA CCGGGGAGGGCAGGTTATTGCTACCGGAACCCCGGAAGAGGTTGCAGCCAACCCTGAATCTTATACGGGACAGTTTTTAA GTAAATATCTCAATAATAAATGGTGA
Upstream 100 bases:
>100_bases AAAGAGGCGGCCGATAACCTGGAGTTTGAACTGGCAGCCCAGATAAGGGATGAAATAAAGGAACTGGAAGAAGAGCTGGA AAAGATGAGGTGAAAAGATA
Downstream 100 bases:
>100_bases TGCCCATGAGATATATTGAAGAACAACTAAAGAGGTTACCTGATCGGCCAGGGGTATACCTGATGAAAGATGAGACAGGT GAGGTTATTTATGTCGGTAA
Product: excinuclease ABC subunit A
Products: NA
Alternate protein names: UvrA protein; Excinuclease ABC subunit A [H]
Number of amino acids: Translated: 941; Mature: 941
Protein sequence:
>941_residues MVKEMIYVKGAQEHNLKNIDVRIPRDKLIVITGLSGSGKSSLAFDTIYAEGQRRYVESLSAYARQFLGQMEKPRVEYIEG LSPAISIDQKTTSKNPRSTVGTVTEIYDYLRLLYARIGRPHCPECGRAISSQSVDEIVDQVLDLPGRTKIQILSPVVRGR KGEHQKVFTRALRDGFVRARVDGRVIILGEEEVSLEKNLKHDIEVVVDRLVIKEGIRERLTDSIETALEYSEGLVIVDVI DGDEMVFSEKFACPECGISLEEMSPRMFSFNSPYGACPNCDGLGIKKEFDPDLILDKEKSISNGAIIPWRNSTSRYYPQL LSALAEEYNFSLDTPLEQLDDDIIDIILYGSDRQLVFPYTNRYGRTRQHKTYFKGIVGYLKRRVNESDSPTAHRRLERYM SERPCSTCQGGRLRPEVLAVTVGGKSIAEFTRYSIKEAYDFIEELNLTEREQYISQEIIKEIKNRLRFLIDVGLDYLTLD RPAGSLSGGEAQRIRLATQIGSGLVGVLYILDEPSIGLHQRDNNRLIRTLEHIRDLGNTVIVVEHDEDTIRAADHIIDIG PRAGKHGGRVVAQGSLEDIVSSKESLTGQYLSGEKKIPVPEKRVRPNGKYLEIKGARQHNLKNIDVKIPLGTFTCVTGVS GSGKSTLINLTLKRKLMQHFYDSTLRPGEHDEIKGLEYVDKIINIDQSPIGRTPRSNPATYTKVFDYIRDVFAKTPEARR MGYKKGRFSFNVKGGRCEACKGDGIIKIEMHFLPDVYVPCEVCGGKRYNRETLEIKYKGKTIADILEMTVEEALEFFANV NPIKRRLQTLYDVGLGYIRLGQPATTLSGGEAQRIKIASELGKRSTGKTIYILDEPTTGLHFEDVKKLLEVLFRLREGGN TVIVIEHNLDVIKAADYIIDLGPEGGDRGGQVIATGTPEEVAANPESYTGQFLSKYLNNKW
Sequences:
>Translated_941_residues MVKEMIYVKGAQEHNLKNIDVRIPRDKLIVITGLSGSGKSSLAFDTIYAEGQRRYVESLSAYARQFLGQMEKPRVEYIEG LSPAISIDQKTTSKNPRSTVGTVTEIYDYLRLLYARIGRPHCPECGRAISSQSVDEIVDQVLDLPGRTKIQILSPVVRGR KGEHQKVFTRALRDGFVRARVDGRVIILGEEEVSLEKNLKHDIEVVVDRLVIKEGIRERLTDSIETALEYSEGLVIVDVI DGDEMVFSEKFACPECGISLEEMSPRMFSFNSPYGACPNCDGLGIKKEFDPDLILDKEKSISNGAIIPWRNSTSRYYPQL LSALAEEYNFSLDTPLEQLDDDIIDIILYGSDRQLVFPYTNRYGRTRQHKTYFKGIVGYLKRRVNESDSPTAHRRLERYM SERPCSTCQGGRLRPEVLAVTVGGKSIAEFTRYSIKEAYDFIEELNLTEREQYISQEIIKEIKNRLRFLIDVGLDYLTLD RPAGSLSGGEAQRIRLATQIGSGLVGVLYILDEPSIGLHQRDNNRLIRTLEHIRDLGNTVIVVEHDEDTIRAADHIIDIG PRAGKHGGRVVAQGSLEDIVSSKESLTGQYLSGEKKIPVPEKRVRPNGKYLEIKGARQHNLKNIDVKIPLGTFTCVTGVS GSGKSTLINLTLKRKLMQHFYDSTLRPGEHDEIKGLEYVDKIINIDQSPIGRTPRSNPATYTKVFDYIRDVFAKTPEARR MGYKKGRFSFNVKGGRCEACKGDGIIKIEMHFLPDVYVPCEVCGGKRYNRETLEIKYKGKTIADILEMTVEEALEFFANV NPIKRRLQTLYDVGLGYIRLGQPATTLSGGEAQRIKIASELGKRSTGKTIYILDEPTTGLHFEDVKKLLEVLFRLREGGN TVIVIEHNLDVIKAADYIIDLGPEGGDRGGQVIATGTPEEVAANPESYTGQFLSKYLNNKW >Mature_941_residues MVKEMIYVKGAQEHNLKNIDVRIPRDKLIVITGLSGSGKSSLAFDTIYAEGQRRYVESLSAYARQFLGQMEKPRVEYIEG LSPAISIDQKTTSKNPRSTVGTVTEIYDYLRLLYARIGRPHCPECGRAISSQSVDEIVDQVLDLPGRTKIQILSPVVRGR KGEHQKVFTRALRDGFVRARVDGRVIILGEEEVSLEKNLKHDIEVVVDRLVIKEGIRERLTDSIETALEYSEGLVIVDVI DGDEMVFSEKFACPECGISLEEMSPRMFSFNSPYGACPNCDGLGIKKEFDPDLILDKEKSISNGAIIPWRNSTSRYYPQL LSALAEEYNFSLDTPLEQLDDDIIDIILYGSDRQLVFPYTNRYGRTRQHKTYFKGIVGYLKRRVNESDSPTAHRRLERYM SERPCSTCQGGRLRPEVLAVTVGGKSIAEFTRYSIKEAYDFIEELNLTEREQYISQEIIKEIKNRLRFLIDVGLDYLTLD RPAGSLSGGEAQRIRLATQIGSGLVGVLYILDEPSIGLHQRDNNRLIRTLEHIRDLGNTVIVVEHDEDTIRAADHIIDIG PRAGKHGGRVVAQGSLEDIVSSKESLTGQYLSGEKKIPVPEKRVRPNGKYLEIKGARQHNLKNIDVKIPLGTFTCVTGVS GSGKSTLINLTLKRKLMQHFYDSTLRPGEHDEIKGLEYVDKIINIDQSPIGRTPRSNPATYTKVFDYIRDVFAKTPEARR MGYKKGRFSFNVKGGRCEACKGDGIIKIEMHFLPDVYVPCEVCGGKRYNRETLEIKYKGKTIADILEMTVEEALEFFANV NPIKRRLQTLYDVGLGYIRLGQPATTLSGGEAQRIKIASELGKRSTGKTIYILDEPTTGLHFEDVKKLLEVLFRLREGGN TVIVIEHNLDVIKAADYIIDLGPEGGDRGGQVIATGTPEEVAANPESYTGQFLSKYLNNKW
Specific function: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion h
COG id: COG0178
COG function: function code L; Excinuclease ATPase subunit
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 2 ABC transporter domains [H]
Homologues:
Organism=Escherichia coli, GI2367343, Length=939, Percent_Identity=58.4664536741214, Blast_Score=1098, Evalue=0.0,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003439 - InterPro: IPR017871 - InterPro: IPR013815 - InterPro: IPR003593 - InterPro: IPR004602 [H]
Pfam domain/function: PF00005 ABC_tran [H]
EC number: NA
Molecular weight: Translated: 105792; Mature: 105792
Theoretical pI: Translated: 7.53; Mature: 7.53
Prosite motif: PS00063 ALDOKETO_REDUCTASE_3 ; PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.4 %Cys (Translated Protein) 1.2 %Met (Translated Protein) 2.6 %Cys+Met (Translated Protein) 1.4 %Cys (Mature Protein) 1.2 %Met (Mature Protein) 2.6 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MVKEMIYVKGAQEHNLKNIDVRIPRDKLIVITGLSGSGKSSLAFDTIYAEGQRRYVESLS CCCCEEEEECCCCCCCCEEEEEECCCCEEEEECCCCCCCCCEEEHHHHHHHHHHHHHHHH AYARQFLGQMEKPRVEYIEGLSPAISIDQKTTSKNPRSTVGTVTEIYDYLRLLYARIGRP HHHHHHHHHCCCCHHHHHCCCCCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCC HCPECGRAISSQSVDEIVDQVLDLPGRTKIQILSPVVRGRKGEHQKVFTRALRDGFVRAR CCCHHHHHHCCCCHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHCCCEEEE VDGRVIILGEEEVSLEKNLKHDIEVVVDRLVIKEGIRERLTDSIETALEYSEGLVIVDVI ECCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEE DGDEMVFSEKFACPECGISLEEMSPRMFSFNSPYGACPNCDGLGIKKEFDPDLILDKEKS CCCCEEHHCCCCCCHHCCCHHHCCCCEEECCCCCCCCCCCCCCCCCCCCCCCEEECCCCC ISNGAIIPWRNSTSRYYPQLLSALAEEYNFSLDTPLEQLDDDIIDIILYGSDRQLVFPYT CCCCCEEECCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHCCCEEEEEEECCCCEEEECCC NRYGRTRQHKTYFKGIVGYLKRRVNESDSPTAHRRLERYMSERPCSTCQGGRLRPEVLAV CCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEEE TVGGKSIAEFTRYSIKEAYDFIEELNLTEREQYISQEIIKEIKNRLRFLIDVGLDYLTLD EECCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEC RPAGSLSGGEAQRIRLATQIGSGLVGVLYILDEPSIGLHQRDNNRLIRTLEHIRDLGNTV CCCCCCCCCCHHHEEEHHHHCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCEE IVVEHDEDTIRAADHIIDIGPRAGKHGGRVVAQGSLEDIVSSKESLTGQYLSGEKKIPVP EEEECCCHHHHHHHHHEECCCCCCCCCCEEEECCCHHHHHCCHHHHCCHHHCCCCCCCCC EKRVRPNGKYLEIKGARQHNLKNIDVKIPLGTFTCVTGVSGSGKSTLINLTLKRKLMQHF HHHCCCCCCEEEEECCCCCCCCEEEEEEECCCEEEECCCCCCCCCEEEEHHHHHHHHHHH YDSTLRPGEHDEIKGLEYVDKIINIDQSPIGRTPRSNPATYTKVFDYIRDVFAKTPEARR HHHCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHH MGYKKGRFSFNVKGGRCEACKGDGIIKIEMHFLPDVYVPCEVCGGKRYNRETLEIKYKGK CCCCCCCEEEEECCCEECCCCCCCEEEEEEEECCCCCCCHHHCCCCCCCCCEEEEEECCC TIADILEMTVEEALEFFANVNPIKRRLQTLYDVGLGYIRLGQPATTLSGGEAQRIKIASE HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCHHEEHHHH LGKRSTGKTIYILDEPTTGLHFEDVKKLLEVLFRLREGGNTVIVIEHNLDVIKAADYIID HCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCEECCCEEEE LGPEGGDRGGQVIATGTPEEVAANPESYTGQFLSKYLNNKW CCCCCCCCCCEEEECCCCHHHHCCCCHHHHHHHHHHHCCCC >Mature Secondary Structure MVKEMIYVKGAQEHNLKNIDVRIPRDKLIVITGLSGSGKSSLAFDTIYAEGQRRYVESLS CCCCEEEEECCCCCCCCEEEEEECCCCEEEEECCCCCCCCCEEEHHHHHHHHHHHHHHHH AYARQFLGQMEKPRVEYIEGLSPAISIDQKTTSKNPRSTVGTVTEIYDYLRLLYARIGRP HHHHHHHHHCCCCHHHHHCCCCCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCC HCPECGRAISSQSVDEIVDQVLDLPGRTKIQILSPVVRGRKGEHQKVFTRALRDGFVRAR CCCHHHHHHCCCCHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHCCCEEEE VDGRVIILGEEEVSLEKNLKHDIEVVVDRLVIKEGIRERLTDSIETALEYSEGLVIVDVI ECCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEE DGDEMVFSEKFACPECGISLEEMSPRMFSFNSPYGACPNCDGLGIKKEFDPDLILDKEKS CCCCEEHHCCCCCCHHCCCHHHCCCCEEECCCCCCCCCCCCCCCCCCCCCCCEEECCCCC ISNGAIIPWRNSTSRYYPQLLSALAEEYNFSLDTPLEQLDDDIIDIILYGSDRQLVFPYT CCCCCEEECCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHCCCEEEEEEECCCCEEEECCC NRYGRTRQHKTYFKGIVGYLKRRVNESDSPTAHRRLERYMSERPCSTCQGGRLRPEVLAV CCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEEE TVGGKSIAEFTRYSIKEAYDFIEELNLTEREQYISQEIIKEIKNRLRFLIDVGLDYLTLD EECCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEC RPAGSLSGGEAQRIRLATQIGSGLVGVLYILDEPSIGLHQRDNNRLIRTLEHIRDLGNTV CCCCCCCCCCHHHEEEHHHHCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCEE IVVEHDEDTIRAADHIIDIGPRAGKHGGRVVAQGSLEDIVSSKESLTGQYLSGEKKIPVP EEEECCCHHHHHHHHHEECCCCCCCCCCEEEECCCHHHHHCCHHHHCCHHHCCCCCCCCC EKRVRPNGKYLEIKGARQHNLKNIDVKIPLGTFTCVTGVSGSGKSTLINLTLKRKLMQHF HHHCCCCCCEEEEECCCCCCCCEEEEEEECCCEEEECCCCCCCCCEEEEHHHHHHHHHHH YDSTLRPGEHDEIKGLEYVDKIINIDQSPIGRTPRSNPATYTKVFDYIRDVFAKTPEARR HHHCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHH MGYKKGRFSFNVKGGRCEACKGDGIIKIEMHFLPDVYVPCEVCGGKRYNRETLEIKYKGK CCCCCCCEEEEECCCEECCCCCCCEEEEEEEECCCCCCCHHHCCCCCCCCCEEEEEECCC TIADILEMTVEEALEFFANVNPIKRRLQTLYDVGLGYIRLGQPATTLSGGEAQRIKIASE HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCHHEEHHHH LGKRSTGKTIYILDEPTTGLHFEDVKKLLEVLFRLREGGNTVIVIEHNLDVIKAADYIID HCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCEECCCEEEE LGPEGGDRGGQVIATGTPEEVAANPESYTGQFLSKYLNNKW CCCCCCCCCCEEEECCCCHHHHCCCCHHHHHHHHHHHCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: DNA [C]
Specific reaction: Protein + DNA = Protein-DNA [C]
General reaction: Hydrolase; Acting on ester bonds [C]
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 11792842 [H]