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The map label for this gene is malZ [C]

Identifier: 220932452

GI number: 220932452

Start: 1731866

End: 1733614

Strand: Reverse

Name: malZ [C]

Synonym: Hore_16160

Alternate gene names: 220932452

Gene position: 1733614-1731866 (Counterclockwise)

Preceding gene: 220932453

Following gene: 220932451

Centisome position: 67.24

GC content: 40.37

Gene sequence:

>1749_bases
ATGAATAGAGCTGCTATATATCATGTATGTGGAGGCAGTTATGCCTTTCCCGTTAATAAAAATACACTGCGGATCAGGTT
GCGGGCTGCACGAAATGACCTTGACAGGGTTGTAGTTGTATATGGAACAAGATACCCCGGAGATGGAGAAGATCCATACT
TAAGTCAGGAGATGGAACTGGTGGCTTGTGATGAGCTTCACGATTATTATGAAGCCGATATTAGACTTGATGATGCCAGA
TTCAGGTACCATTTTTACCTGGAAGACGTTCAGGAAAGCCTGTGGTTAAATGAAAAGGGTTTTTTTGAGGAAAGGCCCAG
GGGTTTCTTCTCTGGGTTTTTCCAGTACCCTTTAATTAATTATGCCGATATTTTCAGTACTCCGGACTGGGTAAAAGATG
CTGTTTTTTATCACATATTTCCGGAAAGGTTTTATAACGGGGATCCATCCAATGACCCCCGTGGAGTTTCCCCCTGGGGT
GGGAAACCCGGTAGAAAATCATTTTTTGGTGGTGATTTAGAGGGGATTATTAAAAAACTCGATTACATAGAAAGCCTCGG
GGTAAAGGCCATTTACCTTACACCTGTGTTTAAATCACCCAGTAACCATAAGTATAATATTGATGACTATTTCCAGATAG
ACCCCCATTTTGGAGACCTTGAAACAGCAAGAAGGATGGTCATAGAAGCCCACAGGCGTGGAATTAAAATTATTTTTGAT
GCGGTATTTAACCATTGTGGTTATGATTTCTTTGCTTTCAAGGATGTTCGTCAAAAGGGGGAGAAGTCACAGTATAAAGA
CTGGTTTGAAATTGAAAGCTTTCCTGTGCAGACGGATCCCACAAATTATAGAACCTTTGCCAATAATATTGCCCGGATGC
CCAAGTTAATGACCGGAAATCCTGAGGTCAGGGAATATTTGATTAACGTGGCAACTTACTGGATTAAAGAACTTGATATT
GATGGATGGCGGCTGGATGTTGCTGATGAGGTCGACCATCATTTCTGGCGGGAGATGCGTAAAGCTGTTAAGGAAATTAA
AGAGGATGCCTACATTGTTGGAGAAGTATGGCATAATTCTGAAGACTGGCTTCAGGGTGATCAATTTGATGCTATTATGA
ATTATCCCTTTACCTATGCTGTAATTGACTTTTTTGCCCGGAACAGAATTGATGCGGGCACTTTTGATGCCCAGCTGGCT
AAAAACAGGATGTTATATCAGGATAGTGTTAATTATGTAATGTTGAATCTTCTTGATAGTCATGATACCCCCAGGGCCCT
TCATTTTTTTGAAGGAAACAAGGAAAAATTCAAACTGGCTGTTTTGTTCCAGATGACATACCTTGGGGCCCCCATGGTCT
ATTACGGTGATGAACTCGGTATGACCGGGGGTGAAGAACCGGCATCACGTGGTTGCATGGTCTGGGATAAAGAAAATCAG
GATCAAAACTTATTAGATTATTATAAAAAACTGATATCAATAAGGAATAAGCTAACCCCTTTACTCCGGGGTAATTATAA
AACAATTTTAGTAGACAATATCAGAAATATTTATGGATTTACACGACATTACAGGGGGCAGTCAGTTATGGTCATTATTA
ATAATAGTCCCCGGCCACAGCAGGTTAAAATTAAAAAGTTTAAAAACAGAGGAACTATTACAGACCATCTGAGTGGACAG
ACATACAATACCACAGATGGTTATTACCTCCTTGACTTATTACCATATCAGGGATTAATCCTGGAATAA

Upstream 100 bases:

>100_bases
CGTTAAAGCTCAGTAAGAAGGAAAGCCCGGGAGTGATAGATAATTATTTGCTCTGTCCAATTTACTACAAAATTTGCTAA
AGGTTAAGGAGCTGAGGGAC

Downstream 100 bases:

>100_bases
AATTAAACATTATTACAAACCCTAACTCTAGTATTATTTTTTTACGGTTGACAATGGGACACAGTAGGGATATAATATTG
TCGTATAGGACTAAAAATGT

Product: alpha amylase catalytic subunit

Products: NA

Alternate protein names: CDase; Cyclomaltodextrin hydrolase, decycling [H]

Number of amino acids: Translated: 582; Mature: 582

Protein sequence:

>582_residues
MNRAAIYHVCGGSYAFPVNKNTLRIRLRAARNDLDRVVVVYGTRYPGDGEDPYLSQEMELVACDELHDYYEADIRLDDAR
FRYHFYLEDVQESLWLNEKGFFEERPRGFFSGFFQYPLINYADIFSTPDWVKDAVFYHIFPERFYNGDPSNDPRGVSPWG
GKPGRKSFFGGDLEGIIKKLDYIESLGVKAIYLTPVFKSPSNHKYNIDDYFQIDPHFGDLETARRMVIEAHRRGIKIIFD
AVFNHCGYDFFAFKDVRQKGEKSQYKDWFEIESFPVQTDPTNYRTFANNIARMPKLMTGNPEVREYLINVATYWIKELDI
DGWRLDVADEVDHHFWREMRKAVKEIKEDAYIVGEVWHNSEDWLQGDQFDAIMNYPFTYAVIDFFARNRIDAGTFDAQLA
KNRMLYQDSVNYVMLNLLDSHDTPRALHFFEGNKEKFKLAVLFQMTYLGAPMVYYGDELGMTGGEEPASRGCMVWDKENQ
DQNLLDYYKKLISIRNKLTPLLRGNYKTILVDNIRNIYGFTRHYRGQSVMVIINNSPRPQQVKIKKFKNRGTITDHLSGQ
TYNTTDGYYLLDLLPYQGLILE

Sequences:

>Translated_582_residues
MNRAAIYHVCGGSYAFPVNKNTLRIRLRAARNDLDRVVVVYGTRYPGDGEDPYLSQEMELVACDELHDYYEADIRLDDAR
FRYHFYLEDVQESLWLNEKGFFEERPRGFFSGFFQYPLINYADIFSTPDWVKDAVFYHIFPERFYNGDPSNDPRGVSPWG
GKPGRKSFFGGDLEGIIKKLDYIESLGVKAIYLTPVFKSPSNHKYNIDDYFQIDPHFGDLETARRMVIEAHRRGIKIIFD
AVFNHCGYDFFAFKDVRQKGEKSQYKDWFEIESFPVQTDPTNYRTFANNIARMPKLMTGNPEVREYLINVATYWIKELDI
DGWRLDVADEVDHHFWREMRKAVKEIKEDAYIVGEVWHNSEDWLQGDQFDAIMNYPFTYAVIDFFARNRIDAGTFDAQLA
KNRMLYQDSVNYVMLNLLDSHDTPRALHFFEGNKEKFKLAVLFQMTYLGAPMVYYGDELGMTGGEEPASRGCMVWDKENQ
DQNLLDYYKKLISIRNKLTPLLRGNYKTILVDNIRNIYGFTRHYRGQSVMVIINNSPRPQQVKIKKFKNRGTITDHLSGQ
TYNTTDGYYLLDLLPYQGLILE
>Mature_582_residues
MNRAAIYHVCGGSYAFPVNKNTLRIRLRAARNDLDRVVVVYGTRYPGDGEDPYLSQEMELVACDELHDYYEADIRLDDAR
FRYHFYLEDVQESLWLNEKGFFEERPRGFFSGFFQYPLINYADIFSTPDWVKDAVFYHIFPERFYNGDPSNDPRGVSPWG
GKPGRKSFFGGDLEGIIKKLDYIESLGVKAIYLTPVFKSPSNHKYNIDDYFQIDPHFGDLETARRMVIEAHRRGIKIIFD
AVFNHCGYDFFAFKDVRQKGEKSQYKDWFEIESFPVQTDPTNYRTFANNIARMPKLMTGNPEVREYLINVATYWIKELDI
DGWRLDVADEVDHHFWREMRKAVKEIKEDAYIVGEVWHNSEDWLQGDQFDAIMNYPFTYAVIDFFARNRIDAGTFDAQLA
KNRMLYQDSVNYVMLNLLDSHDTPRALHFFEGNKEKFKLAVLFQMTYLGAPMVYYGDELGMTGGEEPASRGCMVWDKENQ
DQNLLDYYKKLISIRNKLTPLLRGNYKTILVDNIRNIYGFTRHYRGQSVMVIINNSPRPQQVKIKKFKNRGTITDHLSGQ
TYNTTDGYYLLDLLPYQGLILE

Specific function: Hydrolyzes cyclodextrins. Can also act on linear maltodextrins, with the exception of maltose [H]

COG id: COG0366

COG function: function code G; Glycosidases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 13 family [H]

Homologues:

Organism=Homo sapiens, GI187423904, Length=253, Percent_Identity=24.1106719367589, Blast_Score=83, Evalue=9e-16,
Organism=Escherichia coli, GI1786604, Length=542, Percent_Identity=30.6273062730627, Blast_Score=224, Evalue=2e-59,
Organism=Escherichia coli, GI1790687, Length=389, Percent_Identity=26.7352185089974, Blast_Score=109, Evalue=4e-25,
Organism=Escherichia coli, GI1789995, Length=139, Percent_Identity=35.9712230215827, Blast_Score=89, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6322245, Length=412, Percent_Identity=26.4563106796117, Blast_Score=107, Evalue=8e-24,
Organism=Saccharomyces cerevisiae, GI6321731, Length=421, Percent_Identity=24.4655581947743, Blast_Score=100, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6319776, Length=421, Percent_Identity=24.4655581947743, Blast_Score=99, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6321726, Length=422, Percent_Identity=24.8815165876777, Blast_Score=92, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6324416, Length=415, Percent_Identity=25.0602409638554, Blast_Score=89, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6322241, Length=415, Percent_Identity=25.0602409638554, Blast_Score=89, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6322021, Length=415, Percent_Identity=25.0602409638554, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24586587, Length=228, Percent_Identity=29.8245614035088, Blast_Score=101, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24586599, Length=414, Percent_Identity=26.3285024154589, Blast_Score=99, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24586591, Length=399, Percent_Identity=26.0651629072682, Blast_Score=95, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24586597, Length=423, Percent_Identity=25.0591016548463, Blast_Score=94, Evalue=3e-19,
Organism=Drosophila melanogaster, GI221330053, Length=224, Percent_Identity=29.9107142857143, Blast_Score=90, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24586593, Length=405, Percent_Identity=23.9506172839506, Blast_Score=83, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24583745, Length=589, Percent_Identity=22.7504244482173, Blast_Score=80, Evalue=5e-15,
Organism=Drosophila melanogaster, GI45549022, Length=248, Percent_Identity=25, Blast_Score=79, Evalue=7e-15,
Organism=Drosophila melanogaster, GI24586589, Length=395, Percent_Identity=24.8101265822785, Blast_Score=76, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24583747, Length=240, Percent_Identity=27.9166666666667, Blast_Score=76, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24583749, Length=240, Percent_Identity=27.9166666666667, Blast_Score=76, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013780
- InterPro:   IPR006047
- InterPro:   IPR004185
- InterPro:   IPR006589
- InterPro:   IPR017853
- InterPro:   IPR013781
- InterPro:   IPR013783 [H]

Pfam domain/function: PF00128 Alpha-amylase; PF02903 Alpha-amylase_N [H]

EC number: =3.2.1.54 [H]

Molecular weight: Translated: 68239; Mature: 68239

Theoretical pI: Translated: 6.02; Mature: 6.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRAAIYHVCGGSYAFPVNKNTLRIRLRAARNDLDRVVVVYGTRYPGDGEDPYLSQEMEL
CCCCEEEEEECCEEEECCCCCEEEEEEEECCCCCCEEEEEEECCCCCCCCCCCCCCCCCE
VACDELHDYYEADIRLDDARFRYHFYLEDVQESLWLNEKGFFEERPRGFFSGFFQYPLIN
EEHHHHHHHHHCCEEEECCEEEEEEEHHHHHHHHCCCCCCCCHHCCCHHHHHHHHCCCCC
YADIFSTPDWVKDAVFYHIFPERFYNGDPSNDPRGVSPWGGKPGRKSFFGGDLEGIIKKL
HHHHCCCCHHHHHHHHEEECHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
DYIESLGVKAIYLTPVFKSPSNHKYNIDDYFQIDPHFGDLETARRMVIEAHRRGIKIIFD
HHHHHCCCEEEEEEEEECCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHCCHHHHHH
AVFNHCGYDFFAFKDVRQKGEKSQYKDWFEIESFPVQTDPTNYRTFANNIARMPKLMTGN
HHHHHCCCCHHHHHHHHHCCCHHHCCCHHHHCCCCCCCCCCCHHHHHHHHHHCCHHCCCC
PEVREYLINVATYWIKELDIDGWRLDVADEVDHHFWREMRKAVKEIKEDAYIVGEVWHNS
HHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCC
EDWLQGDQFDAIMNYPFTYAVIDFFARNRIDAGTFDAQLAKNRMLYQDSVNYVMLNLLDS
HHHCCCCCCHHHHCCCHHHHHHHHHHHCCCCCCCCHHHHHHCCEEECCCCCEEEEEECCC
HDTPRALHFFEGNKEKFKLAVLFQMTYLGAPMVYYGDELGMTGGEEPASRGCMVWDKENQ
CCCCCEEEEECCCCCEEEEEEEEEHHHHCCCEEEECCCCCCCCCCCHHHCCCEEECCCCC
DQNLLDYYKKLISIRNKLTPLLRGNYKTILVDNIRNIYGFTRHYRGQSVMVIINNSPRPQ
CCHHHHHHHHHHHHHHHHCHHHCCCEEEEEEHHHHHHHHHHHHCCCCEEEEEECCCCCCC
QVKIKKFKNRGTITDHLSGQTYNTTDGYYLLDLLPYQGLILE
EEHHHHHCCCCCEEECCCCCEECCCCCEEEEEECCCCCEECC
>Mature Secondary Structure
MNRAAIYHVCGGSYAFPVNKNTLRIRLRAARNDLDRVVVVYGTRYPGDGEDPYLSQEMEL
CCCCEEEEEECCEEEECCCCCEEEEEEEECCCCCCEEEEEEECCCCCCCCCCCCCCCCCE
VACDELHDYYEADIRLDDARFRYHFYLEDVQESLWLNEKGFFEERPRGFFSGFFQYPLIN
EEHHHHHHHHHCCEEEECCEEEEEEEHHHHHHHHCCCCCCCCHHCCCHHHHHHHHCCCCC
YADIFSTPDWVKDAVFYHIFPERFYNGDPSNDPRGVSPWGGKPGRKSFFGGDLEGIIKKL
HHHHCCCCHHHHHHHHEEECHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
DYIESLGVKAIYLTPVFKSPSNHKYNIDDYFQIDPHFGDLETARRMVIEAHRRGIKIIFD
HHHHHCCCEEEEEEEEECCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHCCHHHHHH
AVFNHCGYDFFAFKDVRQKGEKSQYKDWFEIESFPVQTDPTNYRTFANNIARMPKLMTGN
HHHHHCCCCHHHHHHHHHCCCHHHCCCHHHHCCCCCCCCCCCHHHHHHHHHHCCHHCCCC
PEVREYLINVATYWIKELDIDGWRLDVADEVDHHFWREMRKAVKEIKEDAYIVGEVWHNS
HHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCC
EDWLQGDQFDAIMNYPFTYAVIDFFARNRIDAGTFDAQLAKNRMLYQDSVNYVMLNLLDS
HHHCCCCCCHHHHCCCHHHHHHHHHHHCCCCCCCCHHHHHHCCEEECCCCCEEEEEECCC
HDTPRALHFFEGNKEKFKLAVLFQMTYLGAPMVYYGDELGMTGGEEPASRGCMVWDKENQ
CCCCCEEEEECCCCCEEEEEEEEEHHHHCCCEEEECCCCCCCCCCCHHHCCCEEECCCCC
DQNLLDYYKKLISIRNKLTPLLRGNYKTILVDNIRNIYGFTRHYRGQSVMVIINNSPRPQ
CCHHHHHHHHHHHHHHHHCHHHCCCEEEEEEHHHHHHHHHHHHCCCCEEEEEECCCCCCC
QVKIKKFKNRGTITDHLSGQTYNTTDGYYLLDLLPYQGLILE
EEHHHHHCCCCCEEECCCCCEECCCCCEEEEEECCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1644767; 8425614 [H]