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The map label for this gene is hgdA [H]

Identifier: 220932444

GI number: 220932444

Start: 1722912

End: 1724192

Strand: Reverse

Name: hgdA [H]

Synonym: Hore_16080

Alternate gene names: 220932444

Gene position: 1724192-1722912 (Counterclockwise)

Preceding gene: 220932445

Following gene: 220932443

Centisome position: 66.88

GC content: 43.56

Gene sequence:

>1281_bases
ATGGGAAGTGGATTATCTGCTTTTTTTTCCTTATTAAGTAAAGAGAGAAAACTAAAGCTGTTTAAAAAGGGGTTAAAAAA
TAGATTTTTATATAAACTGGCTGAACTGGGAAGCAGAACTGGTAGTACTGGTTATATGCAGGAAGCCCTCCTTTATTCAA
TAAAAGAAACCCGGGCGGCATATTTAAAGGAAAGGCCGGTTATCTGGTGTAGTACGTTTGTTCCCAGTGAACTGGTTTAT
GCTCTGGGCGGGGTACCTTTCATGCCAGAGGTAGCAGCAGGTCTTGCGGCCGCTCTGGGTGTAGCCGATGATTTTTTGAG
ACAGGCTGAAGAAGACTGGATAAGTTCGGATCTCTGTAGTATTCACCGGTGTGGCTGGGGGCTTACTAAAGCCGGTTTAC
TTCCTGAACCAGATCTGATTATTGCTGCTTCTCATTTATGTGACGGGGCCAAAAAATATCTACAGCAGATAAGTTATTAT
AAGGGTATCCCTTTTTATCTTCTGGAAACACCTTATCATCCTGATGATGCCGACTGGCTTGCTCATCAAATCAAGGACCT
GGTGAGAGAACTTGGGGGGGTTAAAGAGGATTTTGAAACAGTATTTACATATTCCAACCGGGCATACCGGGCCCATCAGC
GGGTCAACCAATTGAGAAAAAAAATACCGGCCCCCATGTCGGGTGAGGAGGCCATGAATCTTGTCAGTATGGAATTTATG
TCCTCCGGGAGTCCAGCTGCAGTAAACTATTACCGGACCCTTGAAAAAGAGCTAAAGAAGAGAATAAAAGAAAAAAAGGG
GGTTGTACCCCGGGAAAAACACCGTCTCCTCTGGCTTCATCTAAAACCCTACTATAGACAGGAAATATTTACCACCCTGG
CCCGGAATGATGCCGTTATTGCCTTTGAGGAATATAGTCAGTTATACTGGTTACCTTTAGATTCCACTAAACCTTATCAA
AGCCTGGCCTGGAAAATGATAAACCATTTTGGCTGGGGTCCATTAGAGCGGCAGCTGGAACGGATCAGAAAAATGGTGAT
TGATTATAATATAGATGGGGTTATCGGTTTCTCCCACTGGGGTTGCCGTCAGAGTAGTGGTCGTAATGGTTTCCTTAAAA
AAGAGCTTCAGAAAAAAGGAATTCCCTTTTTAAATCTTGATGGTGACCTGGTAGATATCCGCAACTACCGGGAAGGTCAG
ATTATTACCAGACTTCAGGCCTTTATAGAAGTACTGGAAAGCAGAAATGGAGGGATAAACTATGCTGATAGCAGGACTTG
A

Upstream 100 bases:

>100_bases
ATACTATGAGATTAAAAAAGTTATATAAAATAATATTATTAAATTTGTTTTAATAATTCCACCACAAACTTTAAAAAGAT
AGGGAGGATTATAGAGAATA

Downstream 100 bases:

>100_bases
TATAGGGTCACGGACTACCAAGACTGTAATTTTAGAAGATGGAGACTTGGTGTCCTGGGAGATCATGAATACCGGGGCCA
GGACAGCGGGACGGGCCCGG

Product: 2-hydroxyglutaryl-CoA dehydratase D-component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 426; Mature: 425

Protein sequence:

>426_residues
MGSGLSAFFSLLSKERKLKLFKKGLKNRFLYKLAELGSRTGSTGYMQEALLYSIKETRAAYLKERPVIWCSTFVPSELVY
ALGGVPFMPEVAAGLAAALGVADDFLRQAEEDWISSDLCSIHRCGWGLTKAGLLPEPDLIIAASHLCDGAKKYLQQISYY
KGIPFYLLETPYHPDDADWLAHQIKDLVRELGGVKEDFETVFTYSNRAYRAHQRVNQLRKKIPAPMSGEEAMNLVSMEFM
SSGSPAAVNYYRTLEKELKKRIKEKKGVVPREKHRLLWLHLKPYYRQEIFTTLARNDAVIAFEEYSQLYWLPLDSTKPYQ
SLAWKMINHFGWGPLERQLERIRKMVIDYNIDGVIGFSHWGCRQSSGRNGFLKKELQKKGIPFLNLDGDLVDIRNYREGQ
IITRLQAFIEVLESRNGGINYADSRT

Sequences:

>Translated_426_residues
MGSGLSAFFSLLSKERKLKLFKKGLKNRFLYKLAELGSRTGSTGYMQEALLYSIKETRAAYLKERPVIWCSTFVPSELVY
ALGGVPFMPEVAAGLAAALGVADDFLRQAEEDWISSDLCSIHRCGWGLTKAGLLPEPDLIIAASHLCDGAKKYLQQISYY
KGIPFYLLETPYHPDDADWLAHQIKDLVRELGGVKEDFETVFTYSNRAYRAHQRVNQLRKKIPAPMSGEEAMNLVSMEFM
SSGSPAAVNYYRTLEKELKKRIKEKKGVVPREKHRLLWLHLKPYYRQEIFTTLARNDAVIAFEEYSQLYWLPLDSTKPYQ
SLAWKMINHFGWGPLERQLERIRKMVIDYNIDGVIGFSHWGCRQSSGRNGFLKKELQKKGIPFLNLDGDLVDIRNYREGQ
IITRLQAFIEVLESRNGGINYADSRT
>Mature_425_residues
GSGLSAFFSLLSKERKLKLFKKGLKNRFLYKLAELGSRTGSTGYMQEALLYSIKETRAAYLKERPVIWCSTFVPSELVYA
LGGVPFMPEVAAGLAAALGVADDFLRQAEEDWISSDLCSIHRCGWGLTKAGLLPEPDLIIAASHLCDGAKKYLQQISYYK
GIPFYLLETPYHPDDADWLAHQIKDLVRELGGVKEDFETVFTYSNRAYRAHQRVNQLRKKIPAPMSGEEAMNLVSMEFMS
SGSPAAVNYYRTLEKELKKRIKEKKGVVPREKHRLLWLHLKPYYRQEIFTTLARNDAVIAFEEYSQLYWLPLDSTKPYQS
LAWKMINHFGWGPLERQLERIRKMVIDYNIDGVIGFSHWGCRQSSGRNGFLKKELQKKGIPFLNLDGDLVDIRNYREGQI
ITRLQAFIEVLESRNGGINYADSRT

Specific function: Catalyzes the reversible dehydration of 2- hydroxyglutaryl-CoA to glutaconyl-CoA. This is a key step in the fermentation of glutamate. It is activated by hgdC [H]

COG id: COG1775

COG function: function code E; Benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit, BcrC/BadD/HgdB

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010327 [H]

Pfam domain/function: PF06050 HGD-D [H]

EC number: NA

Molecular weight: Translated: 48806; Mature: 48675

Theoretical pI: Translated: 9.47; Mature: 9.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGSGLSAFFSLLSKERKLKLFKKGLKNRFLYKLAELGSRTGSTGYMQEALLYSIKETRAA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
YLKERPVIWCSTFVPSELVYALGGVPFMPEVAAGLAAALGVADDFLRQAEEDWISSDLCS
HHHCCCEEEEECCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IHRCGWGLTKAGLLPEPDLIIAASHLCDGAKKYLQQISYYKGIPFYLLETPYHPDDADWL
HHHCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHH
AHQIKDLVRELGGVKEDFETVFTYSNRAYRAHQRVNQLRKKIPAPMSGEEAMNLVSMEFM
HHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
SSGSPAAVNYYRTLEKELKKRIKEKKGVVPREKHRLLWLHLKPYYRQEIFTTLARNDAVI
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCHHHHHHHHHHHHCCCCEE
AFEEYSQLYWLPLDSTKPYQSLAWKMINHFGWGPLERQLERIRKMVIDYNIDGVIGFSHW
EEECCCCEEEEECCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCEEECCCC
GCRQSSGRNGFLKKELQKKGIPFLNLDGDLVDIRNYREGQIITRLQAFIEVLESRNGGIN
CCCCCCCCCCHHHHHHHHCCCCEEECCCCEEECCCCCCCHHHHHHHHHHHHHHCCCCCCC
YADSRT
CCCCCC
>Mature Secondary Structure 
GSGLSAFFSLLSKERKLKLFKKGLKNRFLYKLAELGSRTGSTGYMQEALLYSIKETRAA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
YLKERPVIWCSTFVPSELVYALGGVPFMPEVAAGLAAALGVADDFLRQAEEDWISSDLCS
HHHCCCEEEEECCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IHRCGWGLTKAGLLPEPDLIIAASHLCDGAKKYLQQISYYKGIPFYLLETPYHPDDADWL
HHHCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHH
AHQIKDLVRELGGVKEDFETVFTYSNRAYRAHQRVNQLRKKIPAPMSGEEAMNLVSMEFM
HHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
SSGSPAAVNYYRTLEKELKKRIKEKKGVVPREKHRLLWLHLKPYYRQEIFTTLARNDAVI
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCHHHHHHHHHHHHCCCCEE
AFEEYSQLYWLPLDSTKPYQSLAWKMINHFGWGPLERQLERIRKMVIDYNIDGVIGFSHW
EEECCCCEEEEECCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCEEECCCC
GCRQSSGRNGFLKKELQKKGIPFLNLDGDLVDIRNYREGQIITRLQAFIEVLESRNGGIN
CCCCCCCCCCHHHHHHHHCCCCEEECCCCEEECCCCCCCHHHHHHHHHHHHHHCCCCCCC
YADSRT
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2659350; 3691501; 8365476; 11106419 [H]