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The map label for this gene is glcK [H]

Identifier: 220932441

GI number: 220932441

Start: 1720418

End: 1721386

Strand: Reverse

Name: glcK [H]

Synonym: Hore_16050

Alternate gene names: 220932441

Gene position: 1721386-1720418 (Counterclockwise)

Preceding gene: 220932442

Following gene: 220932440

Centisome position: 66.77

GC content: 43.65

Gene sequence:

>969_bases
ATGAAAGAATACTATGTAGGTGTTGATTTAGGAGGTACCAAAATACTAACTGCTCTGGCTGATGCCAGAGGAAAGATTGT
TGCGAAAAAGAAGCTACCGACAGAAGCCCGTAAAGGGGAAGAAAAGGTAATACAAAATATTGTGTCATCAATAGATGCTG
TTCTTCAGGAGAAAGGACTATCAAGGGAAGATGTCATTACTCTGGGTGTCGGAAGCCCCGGGCCCTTAAATACACAGGAG
GGTATTATATACCTGGCCCCTAATCTGGGATGGAGGAATGTACATATTAAAGATATCCTTGAGGAGGAAACAGGTATTCC
GGTAATCCTGGAAAATGACGCCAATGCAGCGGCCCTCGGAGAAAAATGGTTTGGGGCCGGCCAGGATGTTGACAACTTAA
TATATATTACTGTCAGTACCGGTATCGGAGGCGGAATTATTATTAATAAGAAAATTTTCCATGGTATCAATGATGGAGCC
GGTGAGGTTGGACATATGGTTATAGAGCCAGGTGGACCTGTCTGTGGTTGTGGTAACAGGGGTTGTTTTGAGGCCGTTGC
TTCCGGGACTGCCATTAATAAAATGGGCCGGGAGGCTGTAAAAGAAAATAAAGCTACCCTGTTAATGGAATTATCAGGAG
GAGATCCCGAGAAAATTGACGGAAGTTTAATTGCCAGAGCTGCCAGGCAGGGAGATGAAGTAGCCAGGAAAATATGGGAT
AAGGCCGGTTATTATCTGGGGATTGGACTTGCCAACCTTTTAAATATTTTTAACCCGGAAATGATAATTCTGGGTGGTGG
TGTCATGAATGCTGGTGATTTAATAATGGAACCAATGAAAAAAAGCTTAAAAGATCATGCTTTAGAATCAGCCTTTAATT
CAGTTGAGATACGCCAGGCTGAGCTGGGCAATGATACTGGAGTAATCGGGGCAGTTGCAGTAGCCATGGGGGACAGGTTA
TTAGAATGA

Upstream 100 bases:

>100_bases
TGCCCTGCCTTTATTAACACTGGGAGTTATAGGAATGATAATTATAAATGGGACAAAACTTACACTTGAAAAATATGATT
AAATAGGAAGGGGAGTTATG

Downstream 100 bases:

>100_bases
AGACCGCAAAAATAGTTGTTGAGGATATAATTAAAAGGTTTTCCCTGGAAGTTCTGGCTGGTGAAGGGGGAAAAAGTAAT
CATATTACTGTCAGTGATAT

Product: glucokinase

Products: NA

Alternate protein names: Glucose kinase [H]

Number of amino acids: Translated: 322; Mature: 322

Protein sequence:

>322_residues
MKEYYVGVDLGGTKILTALADARGKIVAKKKLPTEARKGEEKVIQNIVSSIDAVLQEKGLSREDVITLGVGSPGPLNTQE
GIIYLAPNLGWRNVHIKDILEEETGIPVILENDANAAALGEKWFGAGQDVDNLIYITVSTGIGGGIIINKKIFHGINDGA
GEVGHMVIEPGGPVCGCGNRGCFEAVASGTAINKMGREAVKENKATLLMELSGGDPEKIDGSLIARAARQGDEVARKIWD
KAGYYLGIGLANLLNIFNPEMIILGGGVMNAGDLIMEPMKKSLKDHALESAFNSVEIRQAELGNDTGVIGAVAVAMGDRL
LE

Sequences:

>Translated_322_residues
MKEYYVGVDLGGTKILTALADARGKIVAKKKLPTEARKGEEKVIQNIVSSIDAVLQEKGLSREDVITLGVGSPGPLNTQE
GIIYLAPNLGWRNVHIKDILEEETGIPVILENDANAAALGEKWFGAGQDVDNLIYITVSTGIGGGIIINKKIFHGINDGA
GEVGHMVIEPGGPVCGCGNRGCFEAVASGTAINKMGREAVKENKATLLMELSGGDPEKIDGSLIARAARQGDEVARKIWD
KAGYYLGIGLANLLNIFNPEMIILGGGVMNAGDLIMEPMKKSLKDHALESAFNSVEIRQAELGNDTGVIGAVAVAMGDRL
LE
>Mature_322_residues
MKEYYVGVDLGGTKILTALADARGKIVAKKKLPTEARKGEEKVIQNIVSSIDAVLQEKGLSREDVITLGVGSPGPLNTQE
GIIYLAPNLGWRNVHIKDILEEETGIPVILENDANAAALGEKWFGAGQDVDNLIYITVSTGIGGGIIINKKIFHGINDGA
GEVGHMVIEPGGPVCGCGNRGCFEAVASGTAINKMGREAVKENKATLLMELSGGDPEKIDGSLIARAARQGDEVARKIWD
KAGYYLGIGLANLLNIFNPEMIILGGGVMNAGDLIMEPMKKSLKDHALESAFNSVEIRQAELGNDTGVIGAVAVAMGDRL
LE

Specific function: May Be A Regulator In Specific Sugar Metabolism. May Influence The Rate Of Glucose Uptake Or Glycolysis In Cells In The Rich Medium. [C]

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Homo sapiens, GI298566325, Length=265, Percent_Identity=34.7169811320755, Blast_Score=133, Evalue=3e-31,
Organism=Homo sapiens, GI298566315, Length=265, Percent_Identity=34.7169811320755, Blast_Score=133, Evalue=3e-31,
Organism=Homo sapiens, GI190014632, Length=265, Percent_Identity=34.7169811320755, Blast_Score=132, Evalue=3e-31,
Organism=Homo sapiens, GI4885285, Length=265, Percent_Identity=34.7169811320755, Blast_Score=132, Evalue=3e-31,
Organism=Homo sapiens, GI298566312, Length=120, Percent_Identity=37.5, Blast_Score=80, Evalue=3e-15,
Organism=Escherichia coli, GI1787878, Length=312, Percent_Identity=25.9615384615385, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI1786891, Length=313, Percent_Identity=28.4345047923323, Blast_Score=143, Evalue=2e-35,
Organism=Escherichia coli, GI87082127, Length=238, Percent_Identity=32.3529411764706, Blast_Score=122, Evalue=4e-29,
Organism=Escherichia coli, GI87081733, Length=318, Percent_Identity=30.5031446540881, Blast_Score=101, Evalue=6e-23,
Organism=Escherichia coli, GI1787363, Length=330, Percent_Identity=27.2727272727273, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI87082230, Length=265, Percent_Identity=33.5849056603774, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1790522, Length=271, Percent_Identity=26.5682656826568, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000600
- InterPro:   IPR004654 [H]

Pfam domain/function: PF00480 ROK [H]

EC number: =2.7.1.2 [H]

Molecular weight: Translated: 34000; Mature: 34000

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: PS01125 ROK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEYYVGVDLGGTKILTALADARGKIVAKKKLPTEARKGEEKVIQNIVSSIDAVLQEKGL
CCCEEEEEECCCHHHHHHHHHCCCCEEEECCCCCHHHCCHHHHHHHHHHHHHHHHHHCCC
SREDVITLGVGSPGPLNTQEGIIYLAPNLGWRNVHIKDILEEETGIPVILENDANAAALG
CHHHEEEEECCCCCCCCCCCCEEEECCCCCCCCCHHHHHHHHCCCCCEEEECCCCCHHHH
EKWFGAGQDVDNLIYITVSTGIGGGIIINKKIFHGINDGAGEVGHMVIEPGGPVCGCGNR
HHHCCCCCCCCCEEEEEEECCCCCCEEECHHHHCCCCCCCCCCCEEEECCCCCEECCCCC
GCFEAVASGTAINKMGREAVKENKATLLMELSGGDPEKIDGSLIARAARQGDEVARKIWD
HHHHHHHCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHH
KAGYYLGIGLANLLNIFNPEMIILGGGVMNAGDLIMEPMKKSLKDHALESAFNSVEIRQA
HCCCEEEHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEHH
ELGNDTGVIGAVAVAMGDRLLE
HCCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKEYYVGVDLGGTKILTALADARGKIVAKKKLPTEARKGEEKVIQNIVSSIDAVLQEKGL
CCCEEEEEECCCHHHHHHHHHCCCCEEEECCCCCHHHCCHHHHHHHHHHHHHHHHHHCCC
SREDVITLGVGSPGPLNTQEGIIYLAPNLGWRNVHIKDILEEETGIPVILENDANAAALG
CHHHEEEEECCCCCCCCCCCCEEEECCCCCCCCCHHHHHHHHCCCCCEEEECCCCCHHHH
EKWFGAGQDVDNLIYITVSTGIGGGIIINKKIFHGINDGAGEVGHMVIEPGGPVCGCGNR
HHHCCCCCCCCCEEEEEEECCCCCCEEECHHHHCCCCCCCCCCCEEEECCCCCEECCCCC
GCFEAVASGTAINKMGREAVKENKATLLMELSGGDPEKIDGSLIARAARQGDEVARKIWD
HHHHHHHCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHH
KAGYYLGIGLANLLNIFNPEMIILGGGVMNAGDLIMEPMKKSLKDHALESAFNSVEIRQA
HCCCEEEHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEHH
ELGNDTGVIGAVAVAMGDRLLE
HCCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]