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The map label for this gene is hprK [H]

Identifier: 220932440

GI number: 220932440

Start: 1719495

End: 1720421

Strand: Reverse

Name: hprK [H]

Synonym: Hore_16040

Alternate gene names: 220932440

Gene position: 1720421-1719495 (Counterclockwise)

Preceding gene: 220932441

Following gene: 220932439

Centisome position: 66.73

GC content: 42.29

Gene sequence:

>927_bases
ATGAAGACCGCAAAAATAGTTGTTGAGGATATAATTAAAAGGTTTTCCCTGGAAGTTCTGGCTGGTGAAGGGGGAAAAAG
TAATCATATTACTGTCAGTGATATCAAGCGTCCCGGGATAGAACTGGCCGGATTCTGGAAGTATTTTTCACCGGAGAGGG
TCCAGATATTGGGCCGAACCGAGATGACCTTTCTTAATGAACTTGACAGTGGGGTTATGGAAACAAGGATAAAAAAACTT
ATAGAATATAATCCCTGTTGTATAATTGTGACCAGGAATCTCCCGGCTCCCCGGTTTCTTATTGAGGAAGCAGAAAAAGA
GTCGGTTCCCCTGTTACGGACTCCGGTTTCAACTACAAGGTTTTCGAGTCAGCTTACCACATTTCTTGAGGAAATACTGG
CCCCGGAGGAAGCTATTTCCGGGGTCCTGGTGGATATTTATGGACTGGGGGTTTTAATTAAGGGAAAGAGCGGTATCGGT
AAGAGTGAAACAGCCATCCAGCTGGTAAAAAGAGGCCACAGGCTGGTAGCTGATGATATTATAAAAGTTAAGAAGATTGG
TGAAAGTAAATTGGTAGGTATGGCTCCTGAAGTTTCCAGGTATTTTTTAGAAATGAGAGGCATAGGTATTATTAATGTAA
AATCACTATTTGGGGCAGGGGCGGTTAAGGATTCTTCTCCTATTAATCTGGTTGTTAACCTTGAAATCTGGGATGATAAC
AAGGAATATGACCGTCTTGGGCTTGATGAAAACTATGCTGAAATAATGGGAATAGAAATACCGGAACTAACAATTCCTGT
GAAGCCAGGGAGAAATCTGGCTATGGTTCTGGAAGTAGCGGCCATGAACCTCAGGATGAAAAGTATTGGTTACAATGCAG
CCCGGGATTTTATTAAAAAAGTGGACAAAAACCGCCCATCCAGTTAA

Upstream 100 bases:

>100_bases
AATCAGCCTTTAATTCAGTTGAGATACGCCAGGCTGAGCTGGGCAATGATACTGGAGTAATCGGGGCAGTTGCAGTAGCC
ATGGGGGACAGGTTATTAGA

Downstream 100 bases:

>100_bases
CCTGGGGGTTATATTATGAAAAAACATATAAATATTATTGTTATCTCGCTTCTTATATTAACTCTGATCGTTTTTTCAAT
TGAAAAGGTTCAGAGTGAAG

Product: HPr kinase

Products: NA

Alternate protein names: HPrK/P; HPr(Ser) kinase/phosphorylase [H]

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MKTAKIVVEDIIKRFSLEVLAGEGGKSNHITVSDIKRPGIELAGFWKYFSPERVQILGRTEMTFLNELDSGVMETRIKKL
IEYNPCCIIVTRNLPAPRFLIEEAEKESVPLLRTPVSTTRFSSQLTTFLEEILAPEEAISGVLVDIYGLGVLIKGKSGIG
KSETAIQLVKRGHRLVADDIIKVKKIGESKLVGMAPEVSRYFLEMRGIGIINVKSLFGAGAVKDSSPINLVVNLEIWDDN
KEYDRLGLDENYAEIMGIEIPELTIPVKPGRNLAMVLEVAAMNLRMKSIGYNAARDFIKKVDKNRPSS

Sequences:

>Translated_308_residues
MKTAKIVVEDIIKRFSLEVLAGEGGKSNHITVSDIKRPGIELAGFWKYFSPERVQILGRTEMTFLNELDSGVMETRIKKL
IEYNPCCIIVTRNLPAPRFLIEEAEKESVPLLRTPVSTTRFSSQLTTFLEEILAPEEAISGVLVDIYGLGVLIKGKSGIG
KSETAIQLVKRGHRLVADDIIKVKKIGESKLVGMAPEVSRYFLEMRGIGIINVKSLFGAGAVKDSSPINLVVNLEIWDDN
KEYDRLGLDENYAEIMGIEIPELTIPVKPGRNLAMVLEVAAMNLRMKSIGYNAARDFIKKVDKNRPSS
>Mature_308_residues
MKTAKIVVEDIIKRFSLEVLAGEGGKSNHITVSDIKRPGIELAGFWKYFSPERVQILGRTEMTFLNELDSGVMETRIKKL
IEYNPCCIIVTRNLPAPRFLIEEAEKESVPLLRTPVSTTRFSSQLTTFLEEILAPEEAISGVLVDIYGLGVLIKGKSGIG
KSETAIQLVKRGHRLVADDIIKVKKIGESKLVGMAPEVSRYFLEMRGIGIINVKSLFGAGAVKDSSPINLVVNLEIWDDN
KEYDRLGLDENYAEIMGIEIPELTIPVKPGRNLAMVLEVAAMNLRMKSIGYNAARDFIKKVDKNRPSS

Specific function: Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-pr

COG id: COG1493

COG function: function code T; Serine kinase of the HPr protein, regulates carbohydrate metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HPrK/P family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003755
- InterPro:   IPR011104
- InterPro:   IPR011126 [H]

Pfam domain/function: PF07475 Hpr_kinase_C; PF02603 Hpr_kinase_N [H]

EC number: NA

Molecular weight: Translated: 34220; Mature: 34220

Theoretical pI: Translated: 8.61; Mature: 8.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTAKIVVEDIIKRFSLEVLAGEGGKSNHITVSDIKRPGIELAGFWKYFSPERVQILGRT
CCCHHHHHHHHHHHHCEEEEECCCCCCCCEEEECCCCCCCCEEEHHHCCCCCEEEEECCH
EMTFLNELDSGVMETRIKKLIEYNPCCIIVTRNLPAPRFLIEEAEKESVPLLRTPVSTTR
HHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHCCCCCEEECCCHHHH
FSSQLTTFLEEILAPEEAISGVLVDIYGLGVLIKGKSGIGKSETAIQLVKRGHRLVADDI
HHHHHHHHHHHHHCCHHHHHHHHEEEECCEEEEECCCCCCCHHHHHHHHHCCCHHHHHHH
IKVKKIGESKLVGMAPEVSRYFLEMRGIGIINVKSLFGAGAVKDSSPINLVVNLEIWDDN
HHHHHCCCCCEECCCHHHHHHHHHHCCCCEEEHHHHHCCCCCCCCCCEEEEEEEEEECCC
KEYDRLGLDENYAEIMGIEIPELTIPVKPGRNLAMVLEVAAMNLRMKSIGYNAARDFIKK
CHHHHCCCCCCHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHH
VDKNRPSS
HHCCCCCC
>Mature Secondary Structure
MKTAKIVVEDIIKRFSLEVLAGEGGKSNHITVSDIKRPGIELAGFWKYFSPERVQILGRT
CCCHHHHHHHHHHHHCEEEEECCCCCCCCEEEECCCCCCCCEEEHHHCCCCCEEEEECCH
EMTFLNELDSGVMETRIKKLIEYNPCCIIVTRNLPAPRFLIEEAEKESVPLLRTPVSTTR
HHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHCCCCCEEECCCHHHH
FSSQLTTFLEEILAPEEAISGVLVDIYGLGVLIKGKSGIGKSETAIQLVKRGHRLVADDI
HHHHHHHHHHHHHCCHHHHHHHHEEEECCEEEEECCCCCCCHHHHHHHHHCCCHHHHHHH
IKVKKIGESKLVGMAPEVSRYFLEMRGIGIINVKSLFGAGAVKDSSPINLVVNLEIWDDN
HHHHHCCCCCEECCCHHHHHHHHHHCCCCEEEHHHHHCCCCCCCCCCEEEEEEEEEECCC
KEYDRLGLDENYAEIMGIEIPELTIPVKPGRNLAMVLEVAAMNLRMKSIGYNAARDFIKK
CHHHHCCCCCCHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHH
VDKNRPSS
HHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]