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The map label for this gene is yprA [H]

Identifier: 220932299

GI number: 220932299

Start: 1558208

End: 1560463

Strand: Reverse

Name: yprA [H]

Synonym: Hore_14630

Alternate gene names: 220932299

Gene position: 1560463-1558208 (Counterclockwise)

Preceding gene: 220932300

Following gene: 220932298

Centisome position: 60.53

GC content: 43.35

Gene sequence:

>2256_bases
ATGAATCTATCCCAGATAAAGGACTATCTTAAAAATTCTGATAAATATAAAAACCTGATTACATACTGGAAGCATATTCC
CCCGAAAGAAGCAGAGTTTGTTGACTTTCCCGGAGAATTAGATCCAGGGTTGGCCGGGGTGTTAAGGGAAAAGGGAATTA
CTTCCCTTTATTCCCACCAGGCTGAGTCTTACCGGGCTATTAAAGATGGGAATCATACGGTTATTGTTACCCCGACTGCT
TCCGGAAAGACACTCTGTTATAATCTCCCTGTCCTCGATGATATCCTTAAAGATAAATCCAACCGGGCTCTTTATTTATT
TCCAACCAAGGCTTTATCCCAGGATCAGCTTGCTGAGCTCTATGACCTTATTTCCCGCCTTGATGAGGGGATTAAGACCT
ATACATATGATGGTGATACCCAGGTTCAGGCCCGCAAAAATATTCGTCAATCAGGGCATATTGTTATAACAAATCCTGAT
ATGTTACATACCGGAATCCTTCCCCATCATACTAAGTGGATTAAGTTATTTGAAAACCTTAAGTATGTTGTTATTGATGA
GATCCATACCTACCGTGGAGTTTTCGGAAGTCATGTGGCCAATGTAATCAGGCGGTTAAAGAGGATCTGTAAATTTTATG
GTTCTGATCCGGTCTTTATATGTTCTTCAGCCACCATTGCCAATCCCCGGGAATTTGCCGGTAAGCTTATCGGGGATAAG
GTCCACCTGATTGATAAAAATGGTGCCCCCCGTGGCCCGAGGGACTTTATTTTCTTCAATCCACCGGTTATAAACCGGGA
ACTGGGGATAAGACGTAGTTATGTTCTGGAGTGCAAATCATTCGGTAAGCTATTTTTAGAGAATGATATCAAGACCATTG
TTTTTGCCAGAAGCAGACTGGTAACAGAAGTAATTCTCTCATATTTAAAGGAACACTTTAAAGGCAGAAAAGAGATCAGG
GGTTACCGGGGAGGCTATCTCCCGGGAGAAAGAAGAGAGATAGAAAAGGGTCTTCGAGAGGGTGACATCCTTGGGGTAGT
CAGTACCAATGCCCTGGAGCTGGGCATAGATATTGGACAGCTGGATGTCTGTATTATGGGAGGTTATCCTGGAACCATCG
CCAGTACCTGGCAACAGGCCGGGCGGGCCGGACGGAGGAATGGCCATTCCCTGGCTGTGTTAATAGCTTCAAGCAGTCCT
TTAGACCAGTTTATAGTAAACCAACCTGAATACTTTTTTGAGCAACCCCCAGAAAACGCCCTTATTAACCCTGATAATCT
CTATATCCTTGTCAGCCATATAAAGTGTGCTGCCTTTGAACTTCCCTTTGAAGATGGTGAAACCTTTGGGGTAGAAACAA
CTGATGAAATTCTGGCCTATCTGGAAGAAGAAAAAATATTGAGATATAGAAATGGAAAATGGTACTGGATGGCTGAGCGG
TATCCAGCTGAAGATATTAGCCTCAGGAGTGCCAGCCCCCATGATTTTGCCGTTATAGATGCCACCCGTCAAAGCAAACC
CCGGGTTATCGGTAAGGTTGACCATTTCAGTGCCCTGACTACAATCCATAAAGATGCTATATATCTCCATGAAGGGAAAC
AGTATCAGGTAAAAGAGCTTGATTATGATGGGAAGAAGGCGTATGTAAAACAGGTCAATGTAAATTACTACACTGATGCC
AGCCTGGCTGTAGATTTAAGGGTTTTAGATGAGTTTGATAATAAGGAATGTCAGGGACTCAGAATAGAGCATGGAGAAGT
TGTAGTTTCAGCCAAAGCAACCATGTTCAAGAAAGTTAAATTTAATACCCATGAAAATGTTGGTTATGGTGATATTAACC
TTCCCGAGGTCGAAATGCATACTACATCTTACTGGTTTTCCTTTCCTGGTTATCTGGAAGAACGGTTCGGTAGAAAGGAA
CTTGAAAGCGGTTTACTGGGACTTTCCAACCTCCTTGTGAATATAGCCCCCATTTATTTGATGTGTGACCCCGGTGATAT
TAAATCGACCGTCCAGGTAAAATCACCATATACCGGAAGGCCAACTATTTTTGTTTATGATAGTTATCCGGGCGGGGTTG
GTATGAGTGAGAAGTTATTCCGGATTCATGAAAAGGTTCTGGGCACAGCCCTGAAACAACTTGAAGAGTGTCCCTGTTCT
GGAGGTTGTCCGGGATGTGTTGGTCCCGTCAATGAAATTGGTCTTCAGGGTAAAGATTATACCCGGGTTTTACTTAAGGA
GGCCCTGGGGAGATGA

Upstream 100 bases:

>100_bases
GGGTTATTTCCCCTGCTGTTTGTTGTTTTATTGCCTTGACTGTAAATATAAATAACAGGTATAATAATAGGTGAACATCA
GTACATAAGAGGTGGCTATA

Downstream 100 bases:

>100_bases
ATTTGCGGGAGAAGTTGAAAAAGATAACAGTAGAGGGTGGTAACCGGGGGAATAAAGATAACCAGACATCACATAACACT
CTCAGAATATCGCTAGAAGG

Product: DEAD/DEAH box helicase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 751; Mature: 751

Protein sequence:

>751_residues
MNLSQIKDYLKNSDKYKNLITYWKHIPPKEAEFVDFPGELDPGLAGVLREKGITSLYSHQAESYRAIKDGNHTVIVTPTA
SGKTLCYNLPVLDDILKDKSNRALYLFPTKALSQDQLAELYDLISRLDEGIKTYTYDGDTQVQARKNIRQSGHIVITNPD
MLHTGILPHHTKWIKLFENLKYVVIDEIHTYRGVFGSHVANVIRRLKRICKFYGSDPVFICSSATIANPREFAGKLIGDK
VHLIDKNGAPRGPRDFIFFNPPVINRELGIRRSYVLECKSFGKLFLENDIKTIVFARSRLVTEVILSYLKEHFKGRKEIR
GYRGGYLPGERREIEKGLREGDILGVVSTNALELGIDIGQLDVCIMGGYPGTIASTWQQAGRAGRRNGHSLAVLIASSSP
LDQFIVNQPEYFFEQPPENALINPDNLYILVSHIKCAAFELPFEDGETFGVETTDEILAYLEEEKILRYRNGKWYWMAER
YPAEDISLRSASPHDFAVIDATRQSKPRVIGKVDHFSALTTIHKDAIYLHEGKQYQVKELDYDGKKAYVKQVNVNYYTDA
SLAVDLRVLDEFDNKECQGLRIEHGEVVVSAKATMFKKVKFNTHENVGYGDINLPEVEMHTTSYWFSFPGYLEERFGRKE
LESGLLGLSNLLVNIAPIYLMCDPGDIKSTVQVKSPYTGRPTIFVYDSYPGGVGMSEKLFRIHEKVLGTALKQLEECPCS
GGCPGCVGPVNEIGLQGKDYTRVLLKEALGR

Sequences:

>Translated_751_residues
MNLSQIKDYLKNSDKYKNLITYWKHIPPKEAEFVDFPGELDPGLAGVLREKGITSLYSHQAESYRAIKDGNHTVIVTPTA
SGKTLCYNLPVLDDILKDKSNRALYLFPTKALSQDQLAELYDLISRLDEGIKTYTYDGDTQVQARKNIRQSGHIVITNPD
MLHTGILPHHTKWIKLFENLKYVVIDEIHTYRGVFGSHVANVIRRLKRICKFYGSDPVFICSSATIANPREFAGKLIGDK
VHLIDKNGAPRGPRDFIFFNPPVINRELGIRRSYVLECKSFGKLFLENDIKTIVFARSRLVTEVILSYLKEHFKGRKEIR
GYRGGYLPGERREIEKGLREGDILGVVSTNALELGIDIGQLDVCIMGGYPGTIASTWQQAGRAGRRNGHSLAVLIASSSP
LDQFIVNQPEYFFEQPPENALINPDNLYILVSHIKCAAFELPFEDGETFGVETTDEILAYLEEEKILRYRNGKWYWMAER
YPAEDISLRSASPHDFAVIDATRQSKPRVIGKVDHFSALTTIHKDAIYLHEGKQYQVKELDYDGKKAYVKQVNVNYYTDA
SLAVDLRVLDEFDNKECQGLRIEHGEVVVSAKATMFKKVKFNTHENVGYGDINLPEVEMHTTSYWFSFPGYLEERFGRKE
LESGLLGLSNLLVNIAPIYLMCDPGDIKSTVQVKSPYTGRPTIFVYDSYPGGVGMSEKLFRIHEKVLGTALKQLEECPCS
GGCPGCVGPVNEIGLQGKDYTRVLLKEALGR
>Mature_751_residues
MNLSQIKDYLKNSDKYKNLITYWKHIPPKEAEFVDFPGELDPGLAGVLREKGITSLYSHQAESYRAIKDGNHTVIVTPTA
SGKTLCYNLPVLDDILKDKSNRALYLFPTKALSQDQLAELYDLISRLDEGIKTYTYDGDTQVQARKNIRQSGHIVITNPD
MLHTGILPHHTKWIKLFENLKYVVIDEIHTYRGVFGSHVANVIRRLKRICKFYGSDPVFICSSATIANPREFAGKLIGDK
VHLIDKNGAPRGPRDFIFFNPPVINRELGIRRSYVLECKSFGKLFLENDIKTIVFARSRLVTEVILSYLKEHFKGRKEIR
GYRGGYLPGERREIEKGLREGDILGVVSTNALELGIDIGQLDVCIMGGYPGTIASTWQQAGRAGRRNGHSLAVLIASSSP
LDQFIVNQPEYFFEQPPENALINPDNLYILVSHIKCAAFELPFEDGETFGVETTDEILAYLEEEKILRYRNGKWYWMAER
YPAEDISLRSASPHDFAVIDATRQSKPRVIGKVDHFSALTTIHKDAIYLHEGKQYQVKELDYDGKKAYVKQVNVNYYTDA
SLAVDLRVLDEFDNKECQGLRIEHGEVVVSAKATMFKKVKFNTHENVGYGDINLPEVEMHTTSYWFSFPGYLEERFGRKE
LESGLLGLSNLLVNIAPIYLMCDPGDIKSTVQVKSPYTGRPTIFVYDSYPGGVGMSEKLFRIHEKVLGTALKQLEECPCS
GGCPGCVGPVNEIGLQGKDYTRVLLKEALGR

Specific function: Unknown

COG id: COG1205

COG function: function code R; Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI40217847, Length=228, Percent_Identity=24.5614035087719, Blast_Score=67, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6320497, Length=767, Percent_Identity=33.2464146023468, Blast_Score=403, Evalue=1e-113,
Organism=Saccharomyces cerevisiae, GI9755332, Length=185, Percent_Identity=26.4864864864865, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR018973
- InterPro:   IPR011545
- InterPro:   IPR001650
- InterPro:   IPR014021 [H]

Pfam domain/function: PF00270 DEAD; PF09369 DUF1998; PF00271 Helicase_C [H]

EC number: 3.6.1.- [C]

Molecular weight: Translated: 84811; Mature: 84811

Theoretical pI: Translated: 7.31; Mature: 7.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLSQIKDYLKNSDKYKNLITYWKHIPPKEAEFVDFPGELDPGLAGVLREKGITSLYSHQ
CCHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCEECCCCCCCCCHHHHHHHCCHHHHHHHH
AESYRAIKDGNHTVIVTPTASGKTLCYNLPVLDDILKDKSNRALYLFPTKALSQDQLAEL
HHHHHHHCCCCEEEEEEECCCCCEEEEECCHHHHHHCCCCCCEEEEEECCCCCHHHHHHH
YDLISRLDEGIKTYTYDGDTQVQARKNIRQSGHIVITNPDMLHTGILPHHTKWIKLFENL
HHHHHHHHCCCEEEEECCCCHHHHHHHHHHCCCEEEECCCHHCCCCCCCHHHHHHHHHCC
KYVVIDEIHTYRGVFGSHVANVIRRLKRICKFYGSDPVFICSSATIANPREFAGKLIGDK
CEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHCCCE
VHLIDKNGAPRGPRDFIFFNPPVINRELGIRRSYVLECKSFGKLFLENDIKTIVFARSRL
EEEEECCCCCCCCCCEEEECCCEECCCCCCCHHHHHHHHHHCHHHHHCCHHHHHHHHHHH
VTEVILSYLKEHFKGRKEIRGYRGGYLPGERREIEKGLREGDILGVVSTNALELGIDIGQ
HHHHHHHHHHHHHCCHHHHCCCCCCCCCCHHHHHHHCCCCCCEEEEEECCEEEECCEECC
LDVCIMGGYPGTIASTWQQAGRAGRRNGHSLAVLIASSSPLDQFIVNQPEYFFEQPPENA
EEEEEECCCCCHHHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHCCCCHHHHCCCCCCC
LINPDNLYILVSHIKCAAFELPFEDGETFGVETTDEILAYLEEEKILRYRNGKWYWMAER
CCCCCCEEEEEEECEEEEEECCCCCCCEECCCCHHHHHHHHHHHHHHEEECCCEEEEECC
YPAEDISLRSASPHDFAVIDATRQSKPRVIGKVDHFSALTTIHKDAIYLHEGKQYQVKEL
CCCCCCEECCCCCCCEEEEECCCCCCCCEEEECHHHHHHHHHHHCEEEEECCCEEEEEEC
DYDGKKAYVKQVNVNYYTDASLAVDLRVLDEFDNKECQGLRIEHGEVVVSAKATMFKKVK
CCCCCEEEEEEECCEEEECCCEEEEEEEHHCCCCCCCCCEEEECCCEEEEEHHHEEEEEE
FNTHENVGYGDINLPEVEMHTTSYWFSFPGYLEERFGRKELESGLLGLSNLLVNIAPIYL
CCCCCCCCCCCCCCCEEEEEEEEEEEECCCHHHHHCCHHHHHHHHHHHHHHHHEEEEEEE
MCDPGDIKSTVQVKSPYTGRPTIFVYDSYPGGVGMSEKLFRIHEKVLGTALKQLEECPCS
EECCCCCCCEEEECCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
GGCPGCVGPVNEIGLQGKDYTRVLLKEALGR
CCCCCCCCCHHHHCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MNLSQIKDYLKNSDKYKNLITYWKHIPPKEAEFVDFPGELDPGLAGVLREKGITSLYSHQ
CCHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCEECCCCCCCCCHHHHHHHCCHHHHHHHH
AESYRAIKDGNHTVIVTPTASGKTLCYNLPVLDDILKDKSNRALYLFPTKALSQDQLAEL
HHHHHHHCCCCEEEEEEECCCCCEEEEECCHHHHHHCCCCCCEEEEEECCCCCHHHHHHH
YDLISRLDEGIKTYTYDGDTQVQARKNIRQSGHIVITNPDMLHTGILPHHTKWIKLFENL
HHHHHHHHCCCEEEEECCCCHHHHHHHHHHCCCEEEECCCHHCCCCCCCHHHHHHHHHCC
KYVVIDEIHTYRGVFGSHVANVIRRLKRICKFYGSDPVFICSSATIANPREFAGKLIGDK
CEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHCCCE
VHLIDKNGAPRGPRDFIFFNPPVINRELGIRRSYVLECKSFGKLFLENDIKTIVFARSRL
EEEEECCCCCCCCCCEEEECCCEECCCCCCCHHHHHHHHHHCHHHHHCCHHHHHHHHHHH
VTEVILSYLKEHFKGRKEIRGYRGGYLPGERREIEKGLREGDILGVVSTNALELGIDIGQ
HHHHHHHHHHHHHCCHHHHCCCCCCCCCCHHHHHHHCCCCCCEEEEEECCEEEECCEECC
LDVCIMGGYPGTIASTWQQAGRAGRRNGHSLAVLIASSSPLDQFIVNQPEYFFEQPPENA
EEEEEECCCCCHHHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHCCCCHHHHCCCCCCC
LINPDNLYILVSHIKCAAFELPFEDGETFGVETTDEILAYLEEEKILRYRNGKWYWMAER
CCCCCCEEEEEEECEEEEEECCCCCCCEECCCCHHHHHHHHHHHHHHEEECCCEEEEECC
YPAEDISLRSASPHDFAVIDATRQSKPRVIGKVDHFSALTTIHKDAIYLHEGKQYQVKEL
CCCCCCEECCCCCCCEEEEECCCCCCCCEEEECHHHHHHHHHHHCEEEEECCCEEEEEEC
DYDGKKAYVKQVNVNYYTDASLAVDLRVLDEFDNKECQGLRIEHGEVVVSAKATMFKKVK
CCCCCEEEEEEECCEEEECCCEEEEEEEHHCCCCCCCCCEEEECCCEEEEEHHHEEEEEE
FNTHENVGYGDINLPEVEMHTTSYWFSFPGYLEERFGRKELESGLLGLSNLLVNIAPIYL
CCCCCCCCCCCCCCCEEEEEEEEEEEECCCHHHHHCCHHHHHHHHHHHHHHHHEEEEEEE
MCDPGDIKSTVQVKSPYTGRPTIFVYDSYPGGVGMSEKLFRIHEKVLGTALKQLEECPCS
EECCCCCCCEEEECCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
GGCPGCVGPVNEIGLQGKDYTRVLLKEALGR
CCCCCCCCCHHHHCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on acid anhydrides [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8760912; 9384377 [H]