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The map label for this gene is mog [H]

Identifier: 220932294

GI number: 220932294

Start: 1551126

End: 1551590

Strand: Reverse

Name: mog [H]

Synonym: Hore_14580

Alternate gene names: 220932294

Gene position: 1551590-1551126 (Counterclockwise)

Preceding gene: 220932295

Following gene: 220932292

Centisome position: 60.18

GC content: 41.29

Gene sequence:

>465_bases
ATGATTAAAGTGGCCATACTTTCTATTGCCGGGGGAGATTCTGAAGAAGAGGACCAGACCAAACCTATTATAAAAGAATT
TGTTGATAAAATAGGGGGTAAAGAGGTTTGTTATAAAAGGGTACCTGAGAGCTTTGGAAAAATCAGAGAGGCCCTTTTTA
ATATAAGTGAGAGGGGCATGGCTGATTTAATTTTAACTTCAGGGGGGACAGGTTTTGCCAGAAAAGATGTAACTCCTGAG
GCCACTATGGCAGTAATTGAACGTGAAGTTCCGGGAATAACAGAATTAATGAGGTGGGAATTGATGAAGAGATGCCCTGA
GGCCTGTCTCACCAGGGCCAGGGCCGGTATTAGAAAGTCGACATTGATTGTTAATTTACCTGGAAAACCAGGAGAAATAA
AAGACAGCCTGGAATCCATTTGTACAGTCTTAATCCATGGGTTAGCGGAATTAAAAAAGGTCTAA

Upstream 100 bases:

>100_bases
TTAACTAGTAGAAATTAGTAAAAAAAAGAGTTATAATAATAATTAAGAAATGGGTAGATTCTGGTTGTAATGTTAAGTGA
AAATGGAAAGGGGTAATTTA

Downstream 100 bases:

>100_bases
ATATTTTACATATATTTACTGATAATAATGGCCCCGGACAGGAAAATGCCGAATTGAATGTTTAACCGGGCCATCTGATA
GTCAATACCTTTAAGGTCAT

Product: molybdenum cofactor synthesis domain-containing protein

Products: NA

Alternate protein names: MPT adenylyltransferase [H]

Number of amino acids: Translated: 154; Mature: 154

Protein sequence:

>154_residues
MIKVAILSIAGGDSEEEDQTKPIIKEFVDKIGGKEVCYKRVPESFGKIREALFNISERGMADLILTSGGTGFARKDVTPE
ATMAVIEREVPGITELMRWELMKRCPEACLTRARAGIRKSTLIVNLPGKPGEIKDSLESICTVLIHGLAELKKV

Sequences:

>Translated_154_residues
MIKVAILSIAGGDSEEEDQTKPIIKEFVDKIGGKEVCYKRVPESFGKIREALFNISERGMADLILTSGGTGFARKDVTPE
ATMAVIEREVPGITELMRWELMKRCPEACLTRARAGIRKSTLIVNLPGKPGEIKDSLESICTVLIHGLAELKKV
>Mature_154_residues
MIKVAILSIAGGDSEEEDQTKPIIKEFVDKIGGKEVCYKRVPESFGKIREALFNISERGMADLILTSGGTGFARKDVTPE
ATMAVIEREVPGITELMRWELMKRCPEACLTRARAGIRKSTLIVNLPGKPGEIKDSLESICTVLIHGLAELKKV

Specific function: Catalyzes the adenylation of molybdopterin as part of the biosynthesis of the molybdenum-cofactor [H]

COG id: COG0521

COG function: function code H; Molybdopterin biosynthesis enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaB/mog family [H]

Homologues:

Organism=Homo sapiens, GI66932975, Length=156, Percent_Identity=37.1794871794872, Blast_Score=93, Evalue=1e-19,
Organism=Homo sapiens, GI10880983, Length=156, Percent_Identity=37.1794871794872, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1786190, Length=155, Percent_Identity=35.4838709677419, Blast_Score=92, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17564954, Length=141, Percent_Identity=37.5886524822695, Blast_Score=87, Evalue=2e-18,
Organism=Drosophila melanogaster, GI17136978, Length=134, Percent_Identity=35.0746268656716, Blast_Score=87, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24638841, Length=134, Percent_Identity=35.0746268656716, Blast_Score=87, Evalue=5e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020817
- InterPro:   IPR008284
- InterPro:   IPR001453 [H]

Pfam domain/function: PF00994 MoCF_biosynth [H]

EC number: NA

Molecular weight: Translated: 16900; Mature: 16900

Theoretical pI: Translated: 7.93; Mature: 7.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKVAILSIAGGDSEEEDQTKPIIKEFVDKIGGKEVCYKRVPESFGKIREALFNISERGM
CEEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCH
ADLILTSGGTGFARKDVTPEATMAVIEREVPGITELMRWELMKRCPEACLTRARAGIRKS
HHEEEECCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
TLIVNLPGKPGEIKDSLESICTVLIHGLAELKKV
EEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIKVAILSIAGGDSEEEDQTKPIIKEFVDKIGGKEVCYKRVPESFGKIREALFNISERGM
CEEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCH
ADLILTSGGTGFARKDVTPEATMAVIEREVPGITELMRWELMKRCPEACLTRARAGIRKS
HHEEEECCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
TLIVNLPGKPGEIKDSLESICTVLIHGLAELKKV
EEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]