Click here to switch to the map view.

The map label for this gene is mrdB [H]

Identifier: 220932253

GI number: 220932253

Start: 1505466

End: 1506605

Strand: Reverse

Name: mrdB [H]

Synonym: Hore_14170

Alternate gene names: 220932253

Gene position: 1506605-1505466 (Counterclockwise)

Preceding gene: 220932254

Following gene: 220932252

Centisome position: 58.44

GC content: 36.14

Gene sequence:

>1140_bases
ATGCACTGGAATAAAAAGTTATTGAAAAATTTAAATATATCTATCCCGTTAACTGTTTTTCTATTAATTGTTATAGGGTT
GGTTGCTATTAGCAGTGCTGTTGAAATTAATAAACCCCATTCTTACGGGATGAGGTTTTTGCAGAAACAGATTATTGCCG
TTATACTCGGGGTAATAGCTGTGCTGGTGATTCAATTTTATGATTACAGAATGTTTAAGGATTACATGGATATTATATAT
TTAACTTCGGTTGGAATCCTGGTTGTCCTGCTTATAGCCGGGGAGACCATTGCAGGAGGTAAAATGTGGATTAGCCTGGG
GCCGGTTAATTTTCAGCCGTCAGAGCTTTCCAAGATAATGGTTATTCTGGTTCTGGCCACAGTCCTGGATGAAGAGCAGA
AAAACCTCGAGTATTTAACGGGAATGGCTAAACCTTTTTTATATGTGTTAATACCTTTTGTTTTAATTATTCTCCAGAAT
GATCTGGGAACTTCTTTAGTTTTTCTTTTTATCTTTATTGGTATGCTTTTTGTAGCCGGGGGAAATCTCTTTTACATGGT
TTTGTTTTTTGGTGGAGGTTTTCTGTCCATTGTGTTATATATAATTGCCCATTTTAAATTTAATGTCCCGCTTATATTCC
TTAAAGAATATCAGTTAAACCGGTTAGTTGCTTTTGTTAATCCTGACCTTGATCCCTATAATATTGGGTATAACCTTAAT
CAGTCTAAAATTGCCATTGGTTCAGGAAAGTTGTTTGGCAAGGGCCTATTTGCCGGAACCCAGAACCAGCTAAAGTTTTT
ACCGGAAAAACATACTGATTTTATCATTTCGGTGATCGGTGAAGAATTTGGTTTTATTGGGATATTGATTCTGGTATCAT
TATATATTTTCCTGTTGTGGCAGATATTCAATGTCGCCATAGAGGCAAAAGATAACTATGGGAGGCTGGTTGTAACCGGA
ATAGGCTGTATGTTTTTCTTCCATATTATAGAAAATATTGGCATGGCAATGGGGTTAATGCCAATCACAGGGTTGCCCTT
GCCCTTTATCAGTTATGGTGGTAGTTTTATGGTTTCTTCGCTTGTTGCCATTGGGCTGGTTATAAATGTAAATCTCAGAA
AAAGTAAAATATTATTTTAA

Upstream 100 bases:

>100_bases
ATTCAAACAATGTTAAAATGAAGATAAACCGTAATAAAGATATGATGGCTCTAGTGGCCAATTTTCCCCTGGAAAAAACC
GTTTAGAAGAGGAATATATT

Downstream 100 bases:

>100_bases
GTATAAATAACCCCTCCCTGAAATATATACTTATAAAGGGAGGGGGAAAATAATTGAGACCTGGGGTATCTTTTAGGATT
AACCCCCTTTTTTTATTGGT

Product: cell cycle protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 379; Mature: 379

Protein sequence:

>379_residues
MHWNKKLLKNLNISIPLTVFLLIVIGLVAISSAVEINKPHSYGMRFLQKQIIAVILGVIAVLVIQFYDYRMFKDYMDIIY
LTSVGILVVLLIAGETIAGGKMWISLGPVNFQPSELSKIMVILVLATVLDEEQKNLEYLTGMAKPFLYVLIPFVLIILQN
DLGTSLVFLFIFIGMLFVAGGNLFYMVLFFGGGFLSIVLYIIAHFKFNVPLIFLKEYQLNRLVAFVNPDLDPYNIGYNLN
QSKIAIGSGKLFGKGLFAGTQNQLKFLPEKHTDFIISVIGEEFGFIGILILVSLYIFLLWQIFNVAIEAKDNYGRLVVTG
IGCMFFFHIIENIGMAMGLMPITGLPLPFISYGGSFMVSSLVAIGLVINVNLRKSKILF

Sequences:

>Translated_379_residues
MHWNKKLLKNLNISIPLTVFLLIVIGLVAISSAVEINKPHSYGMRFLQKQIIAVILGVIAVLVIQFYDYRMFKDYMDIIY
LTSVGILVVLLIAGETIAGGKMWISLGPVNFQPSELSKIMVILVLATVLDEEQKNLEYLTGMAKPFLYVLIPFVLIILQN
DLGTSLVFLFIFIGMLFVAGGNLFYMVLFFGGGFLSIVLYIIAHFKFNVPLIFLKEYQLNRLVAFVNPDLDPYNIGYNLN
QSKIAIGSGKLFGKGLFAGTQNQLKFLPEKHTDFIISVIGEEFGFIGILILVSLYIFLLWQIFNVAIEAKDNYGRLVVTG
IGCMFFFHIIENIGMAMGLMPITGLPLPFISYGGSFMVSSLVAIGLVINVNLRKSKILF
>Mature_379_residues
MHWNKKLLKNLNISIPLTVFLLIVIGLVAISSAVEINKPHSYGMRFLQKQIIAVILGVIAVLVIQFYDYRMFKDYMDIIY
LTSVGILVVLLIAGETIAGGKMWISLGPVNFQPSELSKIMVILVLATVLDEEQKNLEYLTGMAKPFLYVLIPFVLIILQN
DLGTSLVFLFIFIGMLFVAGGNLFYMVLFFGGGFLSIVLYIIAHFKFNVPLIFLKEYQLNRLVAFVNPDLDPYNIGYNLN
QSKIAIGSGKLFGKGLFAGTQNQLKFLPEKHTDFIISVIGEEFGFIGILILVSLYIFLLWQIFNVAIEAKDNYGRLVVTG
IGCMFFFHIIENIGMAMGLMPITGLPLPFISYGGSFMVSSLVAIGLVINVNLRKSKILF

Specific function: This is one of the proteins responsible for the rod shape of the cell. It is required for the expression of the enzymatic activity of PBP2, which is thought to synthesize peptidoglycan in the step of initiation of cell elongation [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786277, Length=367, Percent_Identity=33.2425068119891, Blast_Score=181, Evalue=5e-47,
Organism=Escherichia coli, GI1786853, Length=352, Percent_Identity=34.0909090909091, Blast_Score=178, Evalue=5e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR011923 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 42358; Mature: 42358

Theoretical pI: Translated: 9.24; Mature: 9.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHWNKKLLKNLNISIPLTVFLLIVIGLVAISSAVEINKPHSYGMRFLQKQIIAVILGVIA
CCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
VLVIQFYDYRMFKDYMDIIYLTSVGILVVLLIAGETIAGGKMWISLGPVNFQPSELSKIM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCEEEEEECCCCCCHHHHHHHH
VILVLATVLDEEQKNLEYLTGMAKPFLYVLIPFVLIILQNDLGTSLVFLFIFIGMLFVAG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHC
GNLFYMVLFFGGGFLSIVLYIIAHFKFNVPLIFLKEYQLNRLVAFVNPDLDPYNIGYNLN
CCHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEEEEHHHHHHEEEEECCCCCCEECCCCCC
QSKIAIGSGKLFGKGLFAGTQNQLKFLPEKHTDFIISVIGEEFGFIGILILVSLYIFLLW
CCEEEEECCCEEECCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QIFNVAIEAKDNYGRLVVTGIGCMFFFHIIENIGMAMGLMPITGLPLPFISYGGSFMVSS
HHHHHHEEECCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCHHHHHHH
LVAIGLVINVNLRKSKILF
HHHHHHHEEEEECCCCCCC
>Mature Secondary Structure
MHWNKKLLKNLNISIPLTVFLLIVIGLVAISSAVEINKPHSYGMRFLQKQIIAVILGVIA
CCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
VLVIQFYDYRMFKDYMDIIYLTSVGILVVLLIAGETIAGGKMWISLGPVNFQPSELSKIM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCEEEEEECCCCCCHHHHHHHH
VILVLATVLDEEQKNLEYLTGMAKPFLYVLIPFVLIILQNDLGTSLVFLFIFIGMLFVAG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHC
GNLFYMVLFFGGGFLSIVLYIIAHFKFNVPLIFLKEYQLNRLVAFVNPDLDPYNIGYNLN
CCHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEEEEHHHHHHEEEEECCCCCCEECCCCCC
QSKIAIGSGKLFGKGLFAGTQNQLKFLPEKHTDFIISVIGEEFGFIGILILVSLYIFLLW
CCEEEEECCCEEECCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QIFNVAIEAKDNYGRLVVTGIGCMFFFHIIENIGMAMGLMPITGLPLPFISYGGSFMVSS
HHHHHHEEECCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCHHHHHHH
LVAIGLVINVNLRKSKILF
HHHHHHHEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]