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The map label for this gene is 220932252

Identifier: 220932252

GI number: 220932252

Start: 1504552

End: 1505370

Strand: Reverse

Name: 220932252

Synonym: Hore_14160

Alternate gene names: NA

Gene position: 1505370-1504552 (Counterclockwise)

Preceding gene: 220932253

Following gene: 220932251

Centisome position: 58.39

GC content: 36.51

Gene sequence:

>819_bases
TTGGTAGTGGTAGTTTTTGCTCTGGCTGGACTGTTCACAGAAGCAATTATTTCGATAGTTTTAGTAATAACCCACGAGTT
TATTCATTTACTTGTGGCCTACCGGCTGGGTTACCGGCCGGGAAAAATCGAGTTATTCCCCTTCGGGGGTATGGCCGAGT
ATTCAGGTTTGCTGGAGATGAATCCAGGTGATGAAATAAAGGTTGCGGGAGCAGGTCCCCTTTATAACCTGGCAATGGCC
GGTATATTTTATTTAATATACATGTTAACACCACATAATCTTTATTTGTTAATTGTGAAATATAACCTGGTCTTAAGTTT
TTTTAACTTAATTCCAGCTTTACCACTGGATGGGGGACGGGTATTCAGGGCTCTGATGGTTTATAATTCTGGTTTTAAAC
GGGGAACACTAATAGCAGTTAAGCTGGCAAAAATATTAGCAATTTCGGGTGCTGTCATGGGGGGTGTTTGTGTCTTATTA
AATAAATCAAACCTGTGGGTGTTATTAATATCTTTTTTTGTGTATGGAGCTTCCCTTAAAGAAGAAAATCAGATAGTTTA
TCGGCTTGTAAGGTATTTAACCCGACGCCGGCAGGAAAATATAAACCTGACAATTAGCCCTGTTGTTAATAAAGTTGTAA
GAGGGGAAATGCAAGTTGAAGAGGTGATATATCATTTAAACCCTGTAAAATATAATATTTTTATTGTACTCGATAGTAAA
ATGAGATTATCGGGAATTATTACAGAATCACAGTTGATAGATTCTTTTTTCCGGTTAAAAAAGCATAACATTAAATTAAA
TGATATAATAAGAAAATGA

Upstream 100 bases:

>100_bases
TTTAAGTATAAATAACCCCTCCCTGAAATATATACTTATAAAGGGAGGGGGAAAATAATTGAGACCTGGGGTATCTTTTA
GGATTAACCCCCTTTTTTTA

Downstream 100 bases:

>100_bases
GAAATATATGGGGGTGGTTGTGGTGATTGTAAAAGACCAGCTAGAGAAAATATTATACCGGGTTAACAGTCCAACAAGGT
ACATTGGGGATGAATGGAAT

Product: peptidase M50

Products: NA

Alternate protein names: Site-2-type intermembrane protease [H]

Number of amino acids: Translated: 272; Mature: 272

Protein sequence:

>272_residues
MVVVVFALAGLFTEAIISIVLVITHEFIHLLVAYRLGYRPGKIELFPFGGMAEYSGLLEMNPGDEIKVAGAGPLYNLAMA
GIFYLIYMLTPHNLYLLIVKYNLVLSFFNLIPALPLDGGRVFRALMVYNSGFKRGTLIAVKLAKILAISGAVMGGVCVLL
NKSNLWVLLISFFVYGASLKEENQIVYRLVRYLTRRRQENINLTISPVVNKVVRGEMQVEEVIYHLNPVKYNIFIVLDSK
MRLSGIITESQLIDSFFRLKKHNIKLNDIIRK

Sequences:

>Translated_272_residues
MVVVVFALAGLFTEAIISIVLVITHEFIHLLVAYRLGYRPGKIELFPFGGMAEYSGLLEMNPGDEIKVAGAGPLYNLAMA
GIFYLIYMLTPHNLYLLIVKYNLVLSFFNLIPALPLDGGRVFRALMVYNSGFKRGTLIAVKLAKILAISGAVMGGVCVLL
NKSNLWVLLISFFVYGASLKEENQIVYRLVRYLTRRRQENINLTISPVVNKVVRGEMQVEEVIYHLNPVKYNIFIVLDSK
MRLSGIITESQLIDSFFRLKKHNIKLNDIIRK
>Mature_272_residues
MVVVVFALAGLFTEAIISIVLVITHEFIHLLVAYRLGYRPGKIELFPFGGMAEYSGLLEMNPGDEIKVAGAGPLYNLAMA
GIFYLIYMLTPHNLYLLIVKYNLVLSFFNLIPALPLDGGRVFRALMVYNSGFKRGTLIAVKLAKILAISGAVMGGVCVLL
NKSNLWVLLISFFVYGASLKEENQIVYRLVRYLTRRRQENINLTISPVVNKVVRGEMQVEEVIYHLNPVKYNIFIVLDSK
MRLSGIITESQLIDSFFRLKKHNIKLNDIIRK

Specific function: Unknown

COG id: COG1994

COG function: function code R; Zn-dependent proteases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR000644
- InterPro:   IPR008915
- InterPro:   IPR016483 [H]

Pfam domain/function: PF00571 CBS; PF02163 Peptidase_M50 [H]

EC number: NA

Molecular weight: Translated: 30717; Mature: 30717

Theoretical pI: Translated: 10.06; Mature: 10.06

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVVVVFALAGLFTEAIISIVLVITHEFIHLLVAYRLGYRPGKIELFPFGGMAEYSGLLEM
CEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHCCEEEC
NPGDEIKVAGAGPLYNLAMAGIFYLIYMLTPHNLYLLIVKYNLVLSFFNLIPALPLDGGR
CCCCCEEEECCCHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHCCCCCCCHH
VFRALMVYNSGFKRGTLIAVKLAKILAISGAVMGGVCVLLNKSNLWVLLISFFVYGASLK
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHCCCCC
EENQIVYRLVRYLTRRRQENINLTISPVVNKVVRGEMQVEEVIYHLNPVKYNIFIVLDSK
CCHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHCCHHHHHHHHHCCCEEEEEEEEECCC
MRLSGIITESQLIDSFFRLKKHNIKLNDIIRK
CHHHHCCHHHHHHHHHHHHHHCCCCHHHHHCC
>Mature Secondary Structure
MVVVVFALAGLFTEAIISIVLVITHEFIHLLVAYRLGYRPGKIELFPFGGMAEYSGLLEM
CEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHCCEEEC
NPGDEIKVAGAGPLYNLAMAGIFYLIYMLTPHNLYLLIVKYNLVLSFFNLIPALPLDGGR
CCCCCEEEECCCHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHCCCCCCCHH
VFRALMVYNSGFKRGTLIAVKLAKILAISGAVMGGVCVLLNKSNLWVLLISFFVYGASLK
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHCCCCC
EENQIVYRLVRYLTRRRQENINLTISPVVNKVVRGEMQVEEVIYHLNPVKYNIFIVLDSK
CCHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHCCHHHHHHHHHCCCEEEEEEEEECCC
MRLSGIITESQLIDSFFRLKKHNIKLNDIIRK
CHHHHCCHHHHHHHHHHHHHHCCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]