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The map label for this gene is uvrX [H]

Identifier: 220932162

GI number: 220932162

Start: 1424050

End: 1425309

Strand: Reverse

Name: uvrX [H]

Synonym: Hore_13250

Alternate gene names: 220932162

Gene position: 1425309-1424050 (Counterclockwise)

Preceding gene: 220932163

Following gene: 220932161

Centisome position: 55.28

GC content: 42.62

Gene sequence:

>1260_bases
ATGGAGATAGATTACAGTCAGCTTCCCAGAAACAGTATCATGTGTATTGATATGAAGTCTTTTTATGCCAGTATTGAAGC
TGTTGCCAGGGGGCTTGACCCTTTGAAAACCTGCCTTGCTGTAGTGGGCGATAAACAGAGGTCCGGTTCTGTGGTTCTGG
CGGCGACTCCTGCCCTTAAAGAAAAGTATAATATCAGGACCGGTAATAGATTATATGAAATACCGGATTCCTCTGAAATA
AAAATTGTGGAAGCCAGGATGGGGCTTTATCTGGACAAATCTATAGAAACTACATGCCTTTTTAACAGATTTGTTCCCCT
CAGGGATATTCATGTTTATTCAATTGATGAGGCCTGGTTAAAACTGGATGGAACGGAGAGGCTTTTTGGGGATAAATGGG
AGGTAGCTTCTAAAATTAAAGAATTGCTCTTAAAAGAAATGGGACTTCATTGTAGTATTGGGCTGGGTCCTAACATGTTT
CTGGCCAAGGTGGCTATGGATATTGAAGGCAAACGAAAGGGAATTGCTGAATGGACTTATGAAGATGTTCCTGAAAAGTT
ATGGCCAGTAAAACTGGAAAAATGTTGGGGGGTAGGGGTCCGCCTGGCTCGACAATTTAACCGGATTGGGGTTAGGACCG
TTGGTGATCTTGCTCATTTGCCCCTATCCTATCTCGAGAATAAATATGGAATTATGGGTAGCCAGCTTTATTACCATGCC
TGGGGTGTTGACCTCTCCAAATTAGAAGGCCATTATTATAATCAACCTAAAAATGTTGGAAAAGGGGTTACCCTTCTGCG
TGATTACAGTAACCCCAGAGAGATAAAAACTGTTATTATGGAGCTATGCGAAGAAGTAGCCCGGCGGGCCCGCAAGGAAA
ACCTGGCCGGGAAGACAATTGCTCTTACCGTGGGCTTTAGTAAGGATGAAGTGGAAAAGGGGTTTCACGTTCAGAGAACT
ATTAAATACCATACCAATTTGACTATGGATATATACCAGGTATGTTTAGATCTATTTAATGAGAACTATTCAGGACAGGT
GGTAAGAAAACTGGCAGTTTCCCTGGGTAATTTTATTCCTGATTCCAGTATGCAGTTAAGCCTGTTTGAGGATAAGCTTA
AAAAAATTAATCTGGCCCGGACAATGGACAGAATACGCGATAAATATGGTTATACGGCTATCTTAAGGGCCAGGAGCCTG
ACCAGGGGAGCTATAAGCTTCAGGCAGCAAAAGTTAATTGGAGGCCATAAGGCCAGGTAA

Upstream 100 bases:

>100_bases
GGAAATGGATAATTTTTTTATTTGAAAACCGAACACATGTATGGTAATATGAAAATATCCGCTATTGTAGTCGATTAAAA
TTTTAAAGGAGTCTGGTACA

Downstream 100 bases:

>100_bases
GTTCATAAAAAAGATTTAAATAAAAGGATTTTTTTTAAAATAATATAATTTAATATAGGGGGGGTAATTATGTGTGGGCG
GTATATATTATCTGTCGATA

Product: DNA-directed DNA polymerase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 419; Mature: 419

Protein sequence:

>419_residues
MEIDYSQLPRNSIMCIDMKSFYASIEAVARGLDPLKTCLAVVGDKQRSGSVVLAATPALKEKYNIRTGNRLYEIPDSSEI
KIVEARMGLYLDKSIETTCLFNRFVPLRDIHVYSIDEAWLKLDGTERLFGDKWEVASKIKELLLKEMGLHCSIGLGPNMF
LAKVAMDIEGKRKGIAEWTYEDVPEKLWPVKLEKCWGVGVRLARQFNRIGVRTVGDLAHLPLSYLENKYGIMGSQLYYHA
WGVDLSKLEGHYYNQPKNVGKGVTLLRDYSNPREIKTVIMELCEEVARRARKENLAGKTIALTVGFSKDEVEKGFHVQRT
IKYHTNLTMDIYQVCLDLFNENYSGQVVRKLAVSLGNFIPDSSMQLSLFEDKLKKINLARTMDRIRDKYGYTAILRARSL
TRGAISFRQQKLIGGHKAR

Sequences:

>Translated_419_residues
MEIDYSQLPRNSIMCIDMKSFYASIEAVARGLDPLKTCLAVVGDKQRSGSVVLAATPALKEKYNIRTGNRLYEIPDSSEI
KIVEARMGLYLDKSIETTCLFNRFVPLRDIHVYSIDEAWLKLDGTERLFGDKWEVASKIKELLLKEMGLHCSIGLGPNMF
LAKVAMDIEGKRKGIAEWTYEDVPEKLWPVKLEKCWGVGVRLARQFNRIGVRTVGDLAHLPLSYLENKYGIMGSQLYYHA
WGVDLSKLEGHYYNQPKNVGKGVTLLRDYSNPREIKTVIMELCEEVARRARKENLAGKTIALTVGFSKDEVEKGFHVQRT
IKYHTNLTMDIYQVCLDLFNENYSGQVVRKLAVSLGNFIPDSSMQLSLFEDKLKKINLARTMDRIRDKYGYTAILRARSL
TRGAISFRQQKLIGGHKAR
>Mature_419_residues
MEIDYSQLPRNSIMCIDMKSFYASIEAVARGLDPLKTCLAVVGDKQRSGSVVLAATPALKEKYNIRTGNRLYEIPDSSEI
KIVEARMGLYLDKSIETTCLFNRFVPLRDIHVYSIDEAWLKLDGTERLFGDKWEVASKIKELLLKEMGLHCSIGLGPNMF
LAKVAMDIEGKRKGIAEWTYEDVPEKLWPVKLEKCWGVGVRLARQFNRIGVRTVGDLAHLPLSYLENKYGIMGSQLYYHA
WGVDLSKLEGHYYNQPKNVGKGVTLLRDYSNPREIKTVIMELCEEVARRARKENLAGKTIALTVGFSKDEVEKGFHVQRT
IKYHTNLTMDIYQVCLDLFNENYSGQVVRKLAVSLGNFIPDSSMQLSLFEDKLKKINLARTMDRIRDKYGYTAILRARSL
TRGAISFRQQKLIGGHKAR

Specific function: Poorly Processive, Error-Prone DNA Polymerase Involved In Untargeted Mutagenesis. Copies Undamaged DNA At Stalled Replication Forks, Which Arise In Vivo From Mismatched Or Misaligned Primer Ends. These Misaligned Primers Can Be Extended By Poliv. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Escherichia coli, GI1786425, Length=285, Percent_Identity=28.7719298245614, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1787432, Length=394, Percent_Identity=22.8426395939086, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: 2.7.7.7 [C]

Molecular weight: Translated: 47748; Mature: 47748

Theoretical pI: Translated: 9.60; Mature: 9.60

Prosite motif: PS50173 UMUC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIDYSQLPRNSIMCIDMKSFYASIEAVARGLDPLKTCLAVVGDKQRSGSVVLAATPALK
CCCCHHHCCCCCEEEEEHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCEEEEECCHHH
EKYNIRTGNRLYEIPDSSEIKIVEARMGLYLDKSIETTCLFNRFVPLRDIHVYSIDEAWL
HCCCCCCCCEEEECCCCCCEEEEEEHHCEEECCCCCHHHHHHCCCCEEEEEEEEECHHHE
KLDGTERLFGDKWEVASKIKELLLKEMGLHCSIGLGPNMFLAKVAMDIEGKRKGIAEWTY
EECCCHHHCCCHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHCCCCCCCCCHHCCH
EDVPEKLWPVKLEKCWGVGVRLARQFNRIGVRTVGDLAHLPLSYLENKYGIMGSQLYYHA
HHCCHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHCCCCCCCCCCEEEEE
WGVDLSKLEGHYYNQPKNVGKGVTLLRDYSNPREIKTVIMELCEEVARRARKENLAGKTI
ECCCHHHHCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
ALTVGFSKDEVEKGFHVQRTIKYHTNLTMDIYQVCLDLFNENYSGQVVRKLAVSLGNFIP
EEEECCCHHHHHCCCEEEEEEEECCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCC
DSSMQLSLFEDKLKKINLARTMDRIRDKYGYTAILRARSLTRGAISFRQQKLIGGHKAR
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MEIDYSQLPRNSIMCIDMKSFYASIEAVARGLDPLKTCLAVVGDKQRSGSVVLAATPALK
CCCCHHHCCCCCEEEEEHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCEEEEECCHHH
EKYNIRTGNRLYEIPDSSEIKIVEARMGLYLDKSIETTCLFNRFVPLRDIHVYSIDEAWL
HCCCCCCCCEEEECCCCCCEEEEEEHHCEEECCCCCHHHHHHCCCCEEEEEEEEECHHHE
KLDGTERLFGDKWEVASKIKELLLKEMGLHCSIGLGPNMFLAKVAMDIEGKRKGIAEWTY
EECCCHHHCCCHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHCCCCCCCCCHHCCH
EDVPEKLWPVKLEKCWGVGVRLARQFNRIGVRTVGDLAHLPLSYLENKYGIMGSQLYYHA
HHCCHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHCCCCCCCCCCEEEEE
WGVDLSKLEGHYYNQPKNVGKGVTLLRDYSNPREIKTVIMELCEEVARRARKENLAGKTI
ECCCHHHHCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
ALTVGFSKDEVEKGFHVQRTIKYHTNLTMDIYQVCLDLFNENYSGQVVRKLAVSLGNFIP
EEEECCCHHHHHCCCEEEEEEEECCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCC
DSSMQLSLFEDKLKKINLARTMDRIRDKYGYTAILRARSLTRGAISFRQQKLIGGHKAR
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9722542; 9384377 [H]