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The map label for this gene is deoC [H]

Identifier: 220932086

GI number: 220932086

Start: 1342870

End: 1343571

Strand: Reverse

Name: deoC [H]

Synonym: Hore_12490

Alternate gene names: 220932086

Gene position: 1343571-1342870 (Counterclockwise)

Preceding gene: 220932087

Following gene: 220932085

Centisome position: 52.11

GC content: 44.02

Gene sequence:

>702_bases
ATGGCAATCAAACCTCGTGACATGGCAAAAATGATCGACCATACCAACTTGAAACCGACTGCTACCGTTGAAGATATTAA
AAAATTATGTGATGAGGCCAGGGAATATGAGTTTGCTTCTGTCTGTGTCAATCCTATTTTTGTTCCTCTGGCCAGCAAGT
TGCTGGAAGATAGTTCAGTTAAAGTAACTACTGTAGTTGGTTTTCCACTGGGCTCAACTACCACCGAGACCAAGGCCTTT
GAAACAAGGAATGTGATTAAAAATGGAGCCCAGGAAATAGACATGGTAATGAATCTCGGAGCCTTTAAATCAGAGGCATA
TGACCTTGTAAAGGCTGACATAAAGGCAGTAGTAGATGCTACCAAAACCGCAGGTGTTACTTCAGATATTATTGTCAAGG
TTATAATTGAAACCTGCTATCTGGATAATGAGGAAATAGCAAAGGCCTGTGAAATTGCAAAGGAGGCCGGGGCTGATTTT
GTAAAAACCTCAACTGGATTTGGCTCTGATGGGGCCAGGGAAGATGATGTCAGCCTCATGAGGAAGACTGTAGGTAGAGA
GGTTGGGGTTAAAGCAGCCGGAGGGATCCGGACTTTTGATAAAGCACTGGCTATGCTTGATGCAGGGGCCAACAGGATTG
GTACCAGTTCCGGAGTAGCTATTGTTACCGGCGAAACTGATGACGGGGATAAAGAGTATTAA

Upstream 100 bases:

>100_bases
AATTATTATAAAAGAAGGATAATTTATGATAACGAAGAATATAAATATTAAATTAAATACCAGGATATTATAAGAATAAC
ATGATTAAGGAGTGAAAGTT

Downstream 100 bases:

>100_bases
AATATATGCCATTATTTAATACTGAAGGTATTGTCTTAAAACAATTTGATCTCGGTGAGGCTGACAAGATAATTACCTTT
ATTACCAGAGATATGGGAAA

Product: deoxyribose-phosphate aldolase

Products: NA

Alternate protein names: Phosphodeoxyriboaldolase; DERA; Deoxyriboaldolase [H]

Number of amino acids: Translated: 233; Mature: 232

Protein sequence:

>233_residues
MAIKPRDMAKMIDHTNLKPTATVEDIKKLCDEAREYEFASVCVNPIFVPLASKLLEDSSVKVTTVVGFPLGSTTTETKAF
ETRNVIKNGAQEIDMVMNLGAFKSEAYDLVKADIKAVVDATKTAGVTSDIIVKVIIETCYLDNEEIAKACEIAKEAGADF
VKTSTGFGSDGAREDDVSLMRKTVGREVGVKAAGGIRTFDKALAMLDAGANRIGTSSGVAIVTGETDDGDKEY

Sequences:

>Translated_233_residues
MAIKPRDMAKMIDHTNLKPTATVEDIKKLCDEAREYEFASVCVNPIFVPLASKLLEDSSVKVTTVVGFPLGSTTTETKAF
ETRNVIKNGAQEIDMVMNLGAFKSEAYDLVKADIKAVVDATKTAGVTSDIIVKVIIETCYLDNEEIAKACEIAKEAGADF
VKTSTGFGSDGAREDDVSLMRKTVGREVGVKAAGGIRTFDKALAMLDAGANRIGTSSGVAIVTGETDDGDKEY
>Mature_232_residues
AIKPRDMAKMIDHTNLKPTATVEDIKKLCDEAREYEFASVCVNPIFVPLASKLLEDSSVKVTTVVGFPLGSTTTETKAFE
TRNVIKNGAQEIDMVMNLGAFKSEAYDLVKADIKAVVDATKTAGVTSDIIVKVIIETCYLDNEEIAKACEIAKEAGADFV
KTSTGFGSDGAREDDVSLMRKTVGREVGVKAAGGIRTFDKALAMLDAGANRIGTSSGVAIVTGETDDGDKEY

Specific function: Nucleotide and deoxyribonucleotide catabolism. [C]

COG id: COG0274

COG function: function code F; Deoxyribose-phosphate aldolase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the deoC/fbaB aldolase family. DeoC type 1 subfamily [H]

Homologues:

Organism=Homo sapiens, GI116063554, Length=232, Percent_Identity=29.3103448275862, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI1790841, Length=212, Percent_Identity=35.377358490566, Blast_Score=93, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17533015, Length=201, Percent_Identity=30.8457711442786, Blast_Score=66, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR011343
- InterPro:   IPR002915
- InterPro:   IPR022979 [H]

Pfam domain/function: PF01791 DeoC [H]

EC number: =4.1.2.4 [H]

Molecular weight: Translated: 24859; Mature: 24727

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIKPRDMAKMIDHTNLKPTATVEDIKKLCDEAREYEFASVCVNPIFVPLASKLLEDSSV
CCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCE
KVTTVVGFPLGSTTTETKAFETRNVIKNGAQEIDMVMNLGAFKSEAYDLVKADIKAVVDA
EEEEEEECCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
TKTAGVTSDIIVKVIIETCYLDNEEIAKACEIAKEAGADFVKTSTGFGSDGAREDDVSLM
HHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCEECCCCCCCCCCCHHHHHHH
RKTVGREVGVKAAGGIRTFDKALAMLDAGANRIGTSSGVAIVTGETDDGDKEY
HHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCCC
>Mature Secondary Structure 
AIKPRDMAKMIDHTNLKPTATVEDIKKLCDEAREYEFASVCVNPIFVPLASKLLEDSSV
CCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCE
KVTTVVGFPLGSTTTETKAFETRNVIKNGAQEIDMVMNLGAFKSEAYDLVKADIKAVVDA
EEEEEEECCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
TKTAGVTSDIIVKVIIETCYLDNEEIAKACEIAKEAGADFVKTSTGFGSDGAREDDVSLM
HHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCEECCCCCCCCCCCHHHHHHH
RKTVGREVGVKAAGGIRTFDKALAMLDAGANRIGTSSGVAIVTGETDDGDKEY
HHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]