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The map label for this gene is recG [H]

Identifier: 220931855

GI number: 220931855

Start: 1101841

End: 1103892

Strand: Direct

Name: recG [H]

Synonym: Hore_10120

Alternate gene names: 220931855

Gene position: 1101841-1103892 (Clockwise)

Preceding gene: 220931854

Following gene: 220931856

Centisome position: 42.74

GC content: 38.99

Gene sequence:

>2052_bases
ATGAAGGAGAAAATGCCCAGTAGTGTCCAGTTCGTCAGGGGAGTTGGACCACGGTATGCAGAGGTATTAAAAAAATTAAA
TATTAATACTGTCAAAGACCTCCTGTACTACTTTCCCAGGACTTACCAGGACCGAAGCCAGTTTACTCCCATTAAATATA
TAAGACCAGGTTATGAGGTTACAGTACAGGGGGAAATTATCAAAATTGAGGAAAATAAAATCAGGAAGGGGCTTTCAATT
TTAAAAGCCACCATTACTGATGGTAGTGATGTTCTTAATGGAGTCTGGTTTAACCAGAATTACATAAAAAAACAGCTAAA
AAAGGGCCAGACCTATATTTTTAGTGGTAAACTTAATGAAAAAAGTTTTAGATTTAGAAAAAAAGAAATAAGTAATCCAG
TTTTTGAAAAAGTTGATAAAGGAGACAGTATTCATACCGGAAGAATTGTACCTATTTACCCCTTAACTTCAGGTGTCACT
CAGAAGAGATTAAGGACTATAATTTATAACGCCCTTAATGATTATGCCCATCATTTGACCGATTATTTACCTGGTTTTAT
AAGAAAAAAATATAAATTTCCCGACATTTCCAGGAGTATCTGGGGTTTACATTTTCCTGAAAACCGGGAACATTATATAT
ACTCCAGAAGGCGACTTGCCTTTGAGGAGTTGTTTTTTTTACAGCTCCTTGTTTTAAAACGAAAGAAGGGCATTATTGAG
AGCAGGGGAATCAACCATAAAGATGAGGGGGAGGTAATAAAAAAATTTTTAAAATTACTTCCCTTCAGGTTAACTGCAGC
CCAAAAAAGAGTCTGGAGAGAAATAAAAGCCGATATGGAAAAACCCACCCCTATGCAGAGGTTACTCCAGGGAGATGTCG
GTTCCGGTAAGACTATAATAGCAGCCCTGGCCTTAATTGAAACGATGGCCAATGGTTACCAGGGTGTTTTTATGGCTCCA
ACTGAAATACTGGCTGAACAGCATTACCTTAAACTTAAGGACCTTTTAGAGCCATTAGGATACAGAACCGCCCTTCTGGT
TGGAGGTATAACCGGTTCACAGCGTGAGAATATTGAACGGGGTATTGAAGAAAAGAAAATTGATCTTATAGTAGGCACAC
ATACGCTTTTTCAGGAAAGGATTAATTATTTCAGTTTAGGTCTGGTTGTAATTGATGAGCAGCATCGCTTTGGGGTGGAA
CAACGATTCAAACTTGAGAAGAAAGGGGATAACCCTGATGTTCTTGTAATGACAGCTACCCCTATCCCGAGAACTATGGC
TTTAACAATATATGGTGACCTCGACCTTTCTATAATAGATGAGCTGCCTCCCGGAAGGAGTCCTGTAATTACAACCTGGA
GAACACAAAATTCCAGGAAACGGATTTATTCCTTTGTTAAAGAAAAGTTAGAAGAGGGTCGGCAGGCTTATGTGGTCTGT
CCTGTGATTGAACCCTCTGAAGAGCTTGAAGTAGTTTCAGCGTTGGAAATAAAGGAAAAACTTGAAGATAAATATCTTAA
GGGTTATAATGTTGGTCTGCTTCATGGGAAACTTCCCCCGGAAGAAAAAAAGCAGGTTATGGAGGACTTTCGACAGGGGG
TAATAGATGTTCTGGTTTCTACTACAGTTGTTGAAGTAGGGGTTGATGTTCCCAATGCTACTATAATGATTATTGAAAAC
GCCGACCGTTTTGGCTTGGCTCAGCTCCACCAGTTGAGGGGAAGAGTTGGGAGAGGCAAGTATCAATCTTACTGTATACT
TATCGGTAACCCTACGACTGAAGAAGGGAAAAGAAGGCTTAAAGTTATGACCAGCCTTAATGATGGCTTTGAGATTGCAG
ATGAAGATTTAAAAATCAGGGGTCCAGGTGAGTTTTTTGGGACCAGACAACATGGTATACCTGATTTAAAAGTAGCCAGT
CTTATTAAAGATAAAAAACTTTTACAACTGGCCCGGCAAGAGGCTTTTAATATTATTTACTCTACCCGGGACTGGCAGGA
TAAATATAGAAACCTTAAAGAGAGGATAGATGAACTTGATTTAAAGATTTAA

Upstream 100 bases:

>100_bases
TTATATCAGATAGATACTGGATGGATTAGCTCTATTATAGGTTGTCATGCTGGTCCTTCAGTTTACGGGATTGTTTTAAT
TAAAGGGGATATATTAAATT

Downstream 100 bases:

>100_bases
ACCTGAAAGATAATAATATGATAAAAAATTAGGAGTTGGCGCTGTGCCAACTCCTAATTTGGGAGAGGAGAAATTGGAGG
AAGAGTTTTAATGGGGAGGA

Product: ATP-dependent DNA helicase RecG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 683; Mature: 683

Protein sequence:

>683_residues
MKEKMPSSVQFVRGVGPRYAEVLKKLNINTVKDLLYYFPRTYQDRSQFTPIKYIRPGYEVTVQGEIIKIEENKIRKGLSI
LKATITDGSDVLNGVWFNQNYIKKQLKKGQTYIFSGKLNEKSFRFRKKEISNPVFEKVDKGDSIHTGRIVPIYPLTSGVT
QKRLRTIIYNALNDYAHHLTDYLPGFIRKKYKFPDISRSIWGLHFPENREHYIYSRRRLAFEELFFLQLLVLKRKKGIIE
SRGINHKDEGEVIKKFLKLLPFRLTAAQKRVWREIKADMEKPTPMQRLLQGDVGSGKTIIAALALIETMANGYQGVFMAP
TEILAEQHYLKLKDLLEPLGYRTALLVGGITGSQRENIERGIEEKKIDLIVGTHTLFQERINYFSLGLVVIDEQHRFGVE
QRFKLEKKGDNPDVLVMTATPIPRTMALTIYGDLDLSIIDELPPGRSPVITTWRTQNSRKRIYSFVKEKLEEGRQAYVVC
PVIEPSEELEVVSALEIKEKLEDKYLKGYNVGLLHGKLPPEEKKQVMEDFRQGVIDVLVSTTVVEVGVDVPNATIMIIEN
ADRFGLAQLHQLRGRVGRGKYQSYCILIGNPTTEEGKRRLKVMTSLNDGFEIADEDLKIRGPGEFFGTRQHGIPDLKVAS
LIKDKKLLQLARQEAFNIIYSTRDWQDKYRNLKERIDELDLKI

Sequences:

>Translated_683_residues
MKEKMPSSVQFVRGVGPRYAEVLKKLNINTVKDLLYYFPRTYQDRSQFTPIKYIRPGYEVTVQGEIIKIEENKIRKGLSI
LKATITDGSDVLNGVWFNQNYIKKQLKKGQTYIFSGKLNEKSFRFRKKEISNPVFEKVDKGDSIHTGRIVPIYPLTSGVT
QKRLRTIIYNALNDYAHHLTDYLPGFIRKKYKFPDISRSIWGLHFPENREHYIYSRRRLAFEELFFLQLLVLKRKKGIIE
SRGINHKDEGEVIKKFLKLLPFRLTAAQKRVWREIKADMEKPTPMQRLLQGDVGSGKTIIAALALIETMANGYQGVFMAP
TEILAEQHYLKLKDLLEPLGYRTALLVGGITGSQRENIERGIEEKKIDLIVGTHTLFQERINYFSLGLVVIDEQHRFGVE
QRFKLEKKGDNPDVLVMTATPIPRTMALTIYGDLDLSIIDELPPGRSPVITTWRTQNSRKRIYSFVKEKLEEGRQAYVVC
PVIEPSEELEVVSALEIKEKLEDKYLKGYNVGLLHGKLPPEEKKQVMEDFRQGVIDVLVSTTVVEVGVDVPNATIMIIEN
ADRFGLAQLHQLRGRVGRGKYQSYCILIGNPTTEEGKRRLKVMTSLNDGFEIADEDLKIRGPGEFFGTRQHGIPDLKVAS
LIKDKKLLQLARQEAFNIIYSTRDWQDKYRNLKERIDELDLKI
>Mature_683_residues
MKEKMPSSVQFVRGVGPRYAEVLKKLNINTVKDLLYYFPRTYQDRSQFTPIKYIRPGYEVTVQGEIIKIEENKIRKGLSI
LKATITDGSDVLNGVWFNQNYIKKQLKKGQTYIFSGKLNEKSFRFRKKEISNPVFEKVDKGDSIHTGRIVPIYPLTSGVT
QKRLRTIIYNALNDYAHHLTDYLPGFIRKKYKFPDISRSIWGLHFPENREHYIYSRRRLAFEELFFLQLLVLKRKKGIIE
SRGINHKDEGEVIKKFLKLLPFRLTAAQKRVWREIKADMEKPTPMQRLLQGDVGSGKTIIAALALIETMANGYQGVFMAP
TEILAEQHYLKLKDLLEPLGYRTALLVGGITGSQRENIERGIEEKKIDLIVGTHTLFQERINYFSLGLVVIDEQHRFGVE
QRFKLEKKGDNPDVLVMTATPIPRTMALTIYGDLDLSIIDELPPGRSPVITTWRTQNSRKRIYSFVKEKLEEGRQAYVVC
PVIEPSEELEVVSALEIKEKLEDKYLKGYNVGLLHGKLPPEEKKQVMEDFRQGVIDVLVSTTVVEVGVDVPNATIMIIEN
ADRFGLAQLHQLRGRVGRGKYQSYCILIGNPTTEEGKRRLKVMTSLNDGFEIADEDLKIRGPGEFFGTRQHGIPDLKVAS
LIKDKKLLQLARQEAFNIIYSTRDWQDKYRNLKERIDELDLKI

Specific function: Critical role in recombination and DNA repair. Help process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3' to 5' polarity. RecG unwind branched dup

COG id: COG1200

COG function: function code LK; RecG-like helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI2367254, Length=661, Percent_Identity=41.6036308623298, Blast_Score=455, Evalue=1e-129,
Organism=Escherichia coli, GI1787357, Length=396, Percent_Identity=36.1111111111111, Blast_Score=244, Evalue=2e-65,
Organism=Saccharomyces cerevisiae, GI6321360, Length=342, Percent_Identity=28.0701754385965, Blast_Score=68, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004609
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR016027 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 78711; Mature: 78711

Theoretical pI: Translated: 9.97; Mature: 9.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEKMPSSVQFVRGVGPRYAEVLKKLNINTVKDLLYYFPRTYQDRSQFTPIKYIRPGYEV
CCCCCCCHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHCCCCCCCHHCCCCHHEECCCCEE
TVQGEIIKIEENKIRKGLSILKATITDGSDVLNGVWFNQNYIKKQLKKGQTYIFSGKLNE
EEECEEEEEEHHHHHHHHHHHHHHCCCCHHHHHCEECCHHHHHHHHHCCCEEEEECCCCC
KSFRFRKKEISNPVFEKVDKGDSIHTGRIVPIYPLTSGVTQKRLRTIIYNALNDYAHHLT
HHHHHHHHHHCCHHHHHHCCCCCEECCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHH
DYLPGFIRKKYKFPDISRSIWGLHFPENREHYIYSRRRLAFEELFFLQLLVLKRKKGIIE
HHHHHHHHHCCCCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
SRGINHKDEGEVIKKFLKLLPFRLTAAQKRVWREIKADMEKPTPMQRLLQGDVGSGKTII
HCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCHHHH
AALALIETMANGYQGVFMAPTEILAEQHYLKLKDLLEPLGYRTALLVGGITGSQRENIER
HHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHH
GIEEKKIDLIVGTHTLFQERINYFSLGLVVIDEQHRFGVEQRFKLEKKGDNPDVLVMTAT
CCHHCEEEEEECHHHHHHHHHHHEEEEEEEEECHHHCCCHHHHHHHCCCCCCCEEEEECC
PIPRTMALTIYGDLDLSIIDELPPGRSPVITTWRTQNSRKRIYSFVKEKLEEGRQAYVVC
CCCCEEEEEEEECCCHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCEEEEEE
PVIEPSEELEVVSALEIKEKLEDKYLKGYNVGLLHGKLPPEEKKQVMEDFRQGVIDVLVS
ECCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHH
TTVVEVGVDVPNATIMIIENADRFGLAQLHQLRGRVGRGKYQSYCILIGNPTTEEGKRRL
HHHHEECCCCCCCEEEEEECCCCCCHHHHHHHHCCCCCCCCCEEEEEECCCCCHHHHHHH
KVMTSLNDGFEIADEDLKIRGPGEFFGTRQHGIPDLKVASLIKDKKLLQLARQEAFNIIY
HHHHHCCCCCEECCCCEEEECCCHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHC
STRDWQDKYRNLKERIDELDLKI
CCCCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKEKMPSSVQFVRGVGPRYAEVLKKLNINTVKDLLYYFPRTYQDRSQFTPIKYIRPGYEV
CCCCCCCHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHCCCCCCCHHCCCCHHEECCCCEE
TVQGEIIKIEENKIRKGLSILKATITDGSDVLNGVWFNQNYIKKQLKKGQTYIFSGKLNE
EEECEEEEEEHHHHHHHHHHHHHHCCCCHHHHHCEECCHHHHHHHHHCCCEEEEECCCCC
KSFRFRKKEISNPVFEKVDKGDSIHTGRIVPIYPLTSGVTQKRLRTIIYNALNDYAHHLT
HHHHHHHHHHCCHHHHHHCCCCCEECCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHH
DYLPGFIRKKYKFPDISRSIWGLHFPENREHYIYSRRRLAFEELFFLQLLVLKRKKGIIE
HHHHHHHHHCCCCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
SRGINHKDEGEVIKKFLKLLPFRLTAAQKRVWREIKADMEKPTPMQRLLQGDVGSGKTII
HCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCHHHH
AALALIETMANGYQGVFMAPTEILAEQHYLKLKDLLEPLGYRTALLVGGITGSQRENIER
HHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHH
GIEEKKIDLIVGTHTLFQERINYFSLGLVVIDEQHRFGVEQRFKLEKKGDNPDVLVMTAT
CCHHCEEEEEECHHHHHHHHHHHEEEEEEEEECHHHCCCHHHHHHHCCCCCCCEEEEECC
PIPRTMALTIYGDLDLSIIDELPPGRSPVITTWRTQNSRKRIYSFVKEKLEEGRQAYVVC
CCCCEEEEEEEECCCHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCEEEEEE
PVIEPSEELEVVSALEIKEKLEDKYLKGYNVGLLHGKLPPEEKKQVMEDFRQGVIDVLVS
ECCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHH
TTVVEVGVDVPNATIMIIENADRFGLAQLHQLRGRVGRGKYQSYCILIGNPTTEEGKRRL
HHHHEECCCCCCCEEEEEECCCCCCHHHHHHHHCCCCCCCCCEEEEEECCCCCHHHHHHH
KVMTSLNDGFEIADEDLKIRGPGEFFGTRQHGIPDLKVASLIKDKKLLQLARQEAFNIIY
HHHHHCCCCCEECCCCEEEECCCHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHC
STRDWQDKYRNLKERIDELDLKI
CCCCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377 [H]