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The map label for this gene is ribH [H]

Identifier: 220931845

GI number: 220931845

Start: 1093118

End: 1093585

Strand: Direct

Name: ribH [H]

Synonym: Hore_10020

Alternate gene names: 220931845

Gene position: 1093118-1093585 (Clockwise)

Preceding gene: 220931844

Following gene: 220931846

Centisome position: 42.4

GC content: 42.74

Gene sequence:

>468_bases
ATGGGTAAGACTTTTGAAGGAAAATTATTAGGTGAAGGAATAAAGGTTGGAATTGTCGTCAGCAGGTTTAATGAATTTAT
TTCCAGTAAACTTCTTGATGGAGCCCTGGATGGATTAAGCCGCCATGGTGTTATCGATGAGGATATTGATATTGCCTGGG
TTCCGGGTTCCTATGAGATACCCCTGGTTGCCAAAAAAATGGCTTTAAGGGGCAATTATGACGGTGTTATCTGCCTCGGG
GCTGTTATTAGAGGCGAAACCCCCCACTTTGAGTATGTTTCCTCTGAAGTAGCCAAGGGTGTGGCCAAGGTTGGTCTTGA
TTGTGGGGTTCCTGTAATATTCGGTGTATTGACAACTGATACTATAGAACAGGCTATAGCCAGAGCGGGAACAAAAGCTG
GCAATAAAGGATATGATGCAGCCTTGAGTCTGATTGAAATGGTAAACCTGCTGGAAAATTTTAAATAA

Upstream 100 bases:

>100_bases
CCCATTGAAATTGAACCCAATGAAACCAATAAATATTACCTTGAGATAAAAAGGGATAAAATGGGTCATTTATTAAATTT
AGAAGAAAGGGGTAAAAATA

Downstream 100 bases:

>100_bases
TAGAGAATTTTAAAATATAGTCATGAAATTTATTCTTCTGACATCATTTTTAAAAATAACTAAGAGAACAATCTAAAAAT
TATTAGAAGTTTTTAGAGGA

Product: 6,7-dimethyl-8-ribityllumazine synthase

Products: NA

Alternate protein names: DMRL synthase; Lumazine synthase; Riboflavin synthase beta chain [H]

Number of amino acids: Translated: 155; Mature: 154

Protein sequence:

>155_residues
MGKTFEGKLLGEGIKVGIVVSRFNEFISSKLLDGALDGLSRHGVIDEDIDIAWVPGSYEIPLVAKKMALRGNYDGVICLG
AVIRGETPHFEYVSSEVAKGVAKVGLDCGVPVIFGVLTTDTIEQAIARAGTKAGNKGYDAALSLIEMVNLLENFK

Sequences:

>Translated_155_residues
MGKTFEGKLLGEGIKVGIVVSRFNEFISSKLLDGALDGLSRHGVIDEDIDIAWVPGSYEIPLVAKKMALRGNYDGVICLG
AVIRGETPHFEYVSSEVAKGVAKVGLDCGVPVIFGVLTTDTIEQAIARAGTKAGNKGYDAALSLIEMVNLLENFK
>Mature_154_residues
GKTFEGKLLGEGIKVGIVVSRFNEFISSKLLDGALDGLSRHGVIDEDIDIAWVPGSYEIPLVAKKMALRGNYDGVICLGA
VIRGETPHFEYVSSEVAKGVAKVGLDCGVPVIFGVLTTDTIEQAIARAGTKAGNKGYDAALSLIEMVNLLENFK

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The beta subunit catalyzes

COG id: COG0054

COG function: function code H; Riboflavin synthase beta-chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DMRL synthase family [H]

Homologues:

Organism=Escherichia coli, GI1786617, Length=142, Percent_Identity=57.0422535211268, Blast_Score=167, Evalue=4e-43,
Organism=Saccharomyces cerevisiae, GI6324429, Length=146, Percent_Identity=38.3561643835616, Blast_Score=92, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002180 [H]

Pfam domain/function: PF00885 DMRL_synthase [H]

EC number: =2.5.1.9 [H]

Molecular weight: Translated: 16471; Mature: 16340

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKTFEGKLLGEGIKVGIVVSRFNEFISSKLLDGALDGLSRHGVIDEDIDIAWVPGSYEI
CCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCC
PLVAKKMALRGNYDGVICLGAVIRGETPHFEYVSSEVAKGVAKVGLDCGVPVIFGVLTTD
HHHHHHHHHCCCCCCEEEEEHHHCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
TIEQAIARAGTKAGNKGYDAALSLIEMVNLLENFK
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
GKTFEGKLLGEGIKVGIVVSRFNEFISSKLLDGALDGLSRHGVIDEDIDIAWVPGSYEI
CCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCC
PLVAKKMALRGNYDGVICLGAVIRGETPHFEYVSSEVAKGVAKVGLDCGVPVIFGVLTTD
HHHHHHHHHCCCCCCEEEEEHHHCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
TIEQAIARAGTKAGNKGYDAALSLIEMVNLLENFK
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA