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The map label for this gene is malL [H]

Identifier: 220931789

GI number: 220931789

Start: 1019366

End: 1021057

Strand: Direct

Name: malL [H]

Synonym: Hore_09460

Alternate gene names: 220931789

Gene position: 1019366-1021057 (Clockwise)

Preceding gene: 220931788

Following gene: 220931790

Centisome position: 39.54

GC content: 38.42

Gene sequence:

>1692_bases
ATGACTAAAAAAGAGAAAAGCTGGTGGAAAGAGGCGGTAGTTTATCAAGTATACCCGCGTTCTTTTAATGATACTACTGG
TAATGGTATCGGGGACTTAAGGGGTATTATTGAAAAGCTCGATTATATAAAAGACCTTGGTGTTGATGTTATCTGGTTAA
ATCCCGTTTACGAGTCTCCATGTGATGACATGGGGTATGATATTAGCAATTATAGAAAAATATTACCCCAGTTTGGCACC
ATGGAGGATTTTGATCTTCTCCTCTCTGAAATGCATAAGCGGGGATTAAAACTTGTCATGGATCTGGTAGTGAATCATAC
TTCTGATGAACATCGCTGGTTTGTTGAGTCCAGGAAGTCCAAAGATAATCCCTACCGGGATTATTATATCTGGAAAAAGC
CAAAAGCTGATGGTAGCCCTCCCAACAACTGGGTTTCCTATTTCGGGGGTTCTGCCTGGGAGTATGATGAACAAACCGGT
GAATATTATCTCCATCTGTTTTCCAAAAAACAGCCTGATTTGAACTGGGAAAACCCAAAGGTCAGAGAAGAAGTAAAGGA
TATAATGCGTTTCTGGCTTGATAAAGGTGTCGATGGATTTAGAATGGATGTTATTGGATTTATTTCAAAGGATCCTGATT
TTGAAGATTTTCCAACTGATAATCCCAGTGGGAAGGATCTTGGTGATAAATATGCCAATGGGCCCAGATTACATGAATTT
TTACAGGAACTCCATGATGATGTTCTTAGTCACTATGACTGTATGACCGTTGGAGAATGCCCCGGAGTATCACCTGAAGA
TGCCCTGTTAATAGTTGGTAAAGACAGGCGAGAACTCCAGACTCTCTTTCAATTTGAGGGAATGGACATTGATTATGGTA
AAAATGGAAGCCGCTTCAGTATAGGTAACTGGGATGTTCATGGTTTTAAAAAAGTATATACAAAATGGCATAAAAAGTTA
TATGGTAAGGCCTGGAACAGTATTTATCTTATGAACCATGACCAACCACGGGCAGTGTCCAGGTTTGGTGATGATAAAAA
ATACCGCAAAGAATCTGCTAAAATGTTAGCAACCTTCCTGCTGTCTATGTGGGGTACCCCCTATATCTATCAGGGGGAAG
AAATAGGTATGACAAATTGCCCCTTTGAAGGTGTGGAAGAATTCCGGGATATTGAAATGATTAATTATTATAATGAACAG
ATAAGTAAGGGTAAAACTAAGGAAGAAATAATGCCCGGATTATTATACAGAGGACGGGATAATTCCAGGACTCCAATTCA
ATGGAATGACTCCAGAAATGCAGTTTTTTCTGATGCTGAAGAGACCTGGATAAAGGTAAACCCCAATTATACTGAAATTA
ATGTTGAAGAAGCTGAAAAAGACCCTGATTCAATTCTCCATTATTTCCGTCGTATGATTAAAACCAGGAAAGATAATGAT
GTTCTAATATATGGTGACTATGAACTGGTAGATGAAGGAAATGACGATGTGTATGCCTATCGAAGATTTCTAGACAATGA
AGAAATGCTTGTTCTTCTAAACTTTACAGATAAAGAGACAAGCTGTGATGTTAGCCCTTATAACTTAGAAGATAAAGAGC
TGATTATCTCTAATTATAAGGGGGGTCAAAAGGTCAAAGGAACTGAAGTGACTTTAAGGCCTTATGAAGCCAGGATCTAT
AAGATAAAATAA

Upstream 100 bases:

>100_bases
GATGAAATTAAAGATAGTTCTGATAATAAAGCAGTAAATCCTGCTTAAGTTATATAAACAAACATTTAGTAAGCAAAGTT
ATTTAAGGAGGCTGAAGGAA

Downstream 100 bases:

>100_bases
AATGTTTATCCCCGGTCAGTATTGGCCGGGGGTATAATTAATAAATTTTTCAGTAAGTTTTGTAATCAATGTTCAGTATT
AATTTTGTAAAGAGTGTTAA

Product: alpha amylase catalytic subunit

Products: NA

Alternate protein names: Dextrin 6-alpha-D-glucanohydrolase; Oligosaccharide alpha-1,6-glucosidase; Sucrase-isomaltase; Isomaltase [H]

Number of amino acids: Translated: 563; Mature: 562

Protein sequence:

>563_residues
MTKKEKSWWKEAVVYQVYPRSFNDTTGNGIGDLRGIIEKLDYIKDLGVDVIWLNPVYESPCDDMGYDISNYRKILPQFGT
MEDFDLLLSEMHKRGLKLVMDLVVNHTSDEHRWFVESRKSKDNPYRDYYIWKKPKADGSPPNNWVSYFGGSAWEYDEQTG
EYYLHLFSKKQPDLNWENPKVREEVKDIMRFWLDKGVDGFRMDVIGFISKDPDFEDFPTDNPSGKDLGDKYANGPRLHEF
LQELHDDVLSHYDCMTVGECPGVSPEDALLIVGKDRRELQTLFQFEGMDIDYGKNGSRFSIGNWDVHGFKKVYTKWHKKL
YGKAWNSIYLMNHDQPRAVSRFGDDKKYRKESAKMLATFLLSMWGTPYIYQGEEIGMTNCPFEGVEEFRDIEMINYYNEQ
ISKGKTKEEIMPGLLYRGRDNSRTPIQWNDSRNAVFSDAEETWIKVNPNYTEINVEEAEKDPDSILHYFRRMIKTRKDND
VLIYGDYELVDEGNDDVYAYRRFLDNEEMLVLLNFTDKETSCDVSPYNLEDKELIISNYKGGQKVKGTEVTLRPYEARIY
KIK

Sequences:

>Translated_563_residues
MTKKEKSWWKEAVVYQVYPRSFNDTTGNGIGDLRGIIEKLDYIKDLGVDVIWLNPVYESPCDDMGYDISNYRKILPQFGT
MEDFDLLLSEMHKRGLKLVMDLVVNHTSDEHRWFVESRKSKDNPYRDYYIWKKPKADGSPPNNWVSYFGGSAWEYDEQTG
EYYLHLFSKKQPDLNWENPKVREEVKDIMRFWLDKGVDGFRMDVIGFISKDPDFEDFPTDNPSGKDLGDKYANGPRLHEF
LQELHDDVLSHYDCMTVGECPGVSPEDALLIVGKDRRELQTLFQFEGMDIDYGKNGSRFSIGNWDVHGFKKVYTKWHKKL
YGKAWNSIYLMNHDQPRAVSRFGDDKKYRKESAKMLATFLLSMWGTPYIYQGEEIGMTNCPFEGVEEFRDIEMINYYNEQ
ISKGKTKEEIMPGLLYRGRDNSRTPIQWNDSRNAVFSDAEETWIKVNPNYTEINVEEAEKDPDSILHYFRRMIKTRKDND
VLIYGDYELVDEGNDDVYAYRRFLDNEEMLVLLNFTDKETSCDVSPYNLEDKELIISNYKGGQKVKGTEVTLRPYEARIY
KIK
>Mature_562_residues
TKKEKSWWKEAVVYQVYPRSFNDTTGNGIGDLRGIIEKLDYIKDLGVDVIWLNPVYESPCDDMGYDISNYRKILPQFGTM
EDFDLLLSEMHKRGLKLVMDLVVNHTSDEHRWFVESRKSKDNPYRDYYIWKKPKADGSPPNNWVSYFGGSAWEYDEQTGE
YYLHLFSKKQPDLNWENPKVREEVKDIMRFWLDKGVDGFRMDVIGFISKDPDFEDFPTDNPSGKDLGDKYANGPRLHEFL
QELHDDVLSHYDCMTVGECPGVSPEDALLIVGKDRRELQTLFQFEGMDIDYGKNGSRFSIGNWDVHGFKKVYTKWHKKLY
GKAWNSIYLMNHDQPRAVSRFGDDKKYRKESAKMLATFLLSMWGTPYIYQGEEIGMTNCPFEGVEEFRDIEMINYYNEQI
SKGKTKEEIMPGLLYRGRDNSRTPIQWNDSRNAVFSDAEETWIKVNPNYTEINVEEAEKDPDSILHYFRRMIKTRKDNDV
LIYGDYELVDEGNDDVYAYRRFLDNEEMLVLLNFTDKETSCDVSPYNLEDKELIISNYKGGQKVKGTEVTLRPYEARIYK
IK

Specific function: Unknown

COG id: COG0366

COG function: function code G; Glycosidases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 13 family [H]

Homologues:

Organism=Homo sapiens, GI187423904, Length=536, Percent_Identity=32.089552238806, Blast_Score=270, Evalue=4e-72,
Organism=Homo sapiens, GI61744475, Length=134, Percent_Identity=28.3582089552239, Blast_Score=67, Evalue=5e-11,
Organism=Homo sapiens, GI61744481, Length=134, Percent_Identity=28.3582089552239, Blast_Score=67, Evalue=5e-11,
Organism=Homo sapiens, GI61744477, Length=134, Percent_Identity=28.3582089552239, Blast_Score=67, Evalue=5e-11,
Organism=Homo sapiens, GI65506891, Length=134, Percent_Identity=28.3582089552239, Blast_Score=67, Evalue=6e-11,
Organism=Homo sapiens, GI61744479, Length=134, Percent_Identity=28.3582089552239, Blast_Score=67, Evalue=6e-11,
Organism=Homo sapiens, GI61744483, Length=134, Percent_Identity=28.3582089552239, Blast_Score=67, Evalue=6e-11,
Organism=Escherichia coli, GI1790687, Length=555, Percent_Identity=43.2432432432432, Blast_Score=481, Evalue=1e-137,
Organism=Escherichia coli, GI1786604, Length=215, Percent_Identity=28.8372093023256, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI87081873, Length=162, Percent_Identity=25.9259259259259, Blast_Score=64, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI25147709, Length=528, Percent_Identity=24.0530303030303, Blast_Score=128, Evalue=6e-30,
Organism=Caenorhabditis elegans, GI32565753, Length=534, Percent_Identity=24.3445692883895, Blast_Score=128, Evalue=6e-30,
Organism=Saccharomyces cerevisiae, GI6321726, Length=579, Percent_Identity=41.9689119170984, Blast_Score=425, Evalue=1e-119,
Organism=Saccharomyces cerevisiae, GI6322245, Length=580, Percent_Identity=40.3448275862069, Blast_Score=419, Evalue=1e-118,
Organism=Saccharomyces cerevisiae, GI6322241, Length=583, Percent_Identity=41.1663807890223, Blast_Score=414, Evalue=1e-116,
Organism=Saccharomyces cerevisiae, GI6322021, Length=583, Percent_Identity=41.1663807890223, Blast_Score=414, Evalue=1e-116,
Organism=Saccharomyces cerevisiae, GI6324416, Length=583, Percent_Identity=40.9948542024014, Blast_Score=412, Evalue=1e-116,
Organism=Saccharomyces cerevisiae, GI6321731, Length=583, Percent_Identity=40.6518010291595, Blast_Score=407, Evalue=1e-114,
Organism=Saccharomyces cerevisiae, GI6319776, Length=583, Percent_Identity=40.6518010291595, Blast_Score=407, Evalue=1e-114,
Organism=Drosophila melanogaster, GI221330053, Length=580, Percent_Identity=35, Blast_Score=315, Evalue=6e-86,
Organism=Drosophila melanogaster, GI24586593, Length=583, Percent_Identity=33.6192109777015, Blast_Score=311, Evalue=6e-85,
Organism=Drosophila melanogaster, GI24583745, Length=585, Percent_Identity=32.6495726495726, Blast_Score=310, Evalue=1e-84,
Organism=Drosophila melanogaster, GI24583747, Length=558, Percent_Identity=34.2293906810036, Blast_Score=302, Evalue=5e-82,
Organism=Drosophila melanogaster, GI24583749, Length=558, Percent_Identity=34.2293906810036, Blast_Score=302, Evalue=5e-82,
Organism=Drosophila melanogaster, GI24586599, Length=583, Percent_Identity=32.9331046312178, Blast_Score=282, Evalue=4e-76,
Organism=Drosophila melanogaster, GI24586589, Length=550, Percent_Identity=34.7272727272727, Blast_Score=280, Evalue=2e-75,
Organism=Drosophila melanogaster, GI45549022, Length=582, Percent_Identity=33.1615120274914, Blast_Score=274, Evalue=1e-73,
Organism=Drosophila melanogaster, GI24586597, Length=544, Percent_Identity=33.4558823529412, Blast_Score=273, Evalue=2e-73,
Organism=Drosophila melanogaster, GI24586587, Length=587, Percent_Identity=31.6865417376491, Blast_Score=273, Evalue=3e-73,
Organism=Drosophila melanogaster, GI281360393, Length=528, Percent_Identity=31.6287878787879, Blast_Score=239, Evalue=4e-63,
Organism=Drosophila melanogaster, GI24586591, Length=202, Percent_Identity=53.960396039604, Blast_Score=235, Evalue=5e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013780
- InterPro:   IPR006047
- InterPro:   IPR006589
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00128 Alpha-amylase [H]

EC number: =3.2.1.10 [H]

Molecular weight: Translated: 66181; Mature: 66050

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKKEKSWWKEAVVYQVYPRSFNDTTGNGIGDLRGIIEKLDYIKDLGVDVIWLNPVYESP
CCCCHHHHHHHCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCC
CDDMGYDISNYRKILPQFGTMEDFDLLLSEMHKRGLKLVMDLVVNHTSDEHRWFVESRKS
CCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCC
KDNPYRDYYIWKKPKADGSPPNNWVSYFGGSAWEYDEQTGEYYLHLFSKKQPDLNWENPK
CCCCCCCEEEEECCCCCCCCCHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCH
VREEVKDIMRFWLDKGVDGFRMDVIGFISKDPDFEDFPTDNPSGKDLGDKYANGPRLHEF
HHHHHHHHHHHHHHCCCCCEEEHHHHHHCCCCCCCCCCCCCCCCCCCCHHHCCCHHHHHH
LQELHDDVLSHYDCMTVGECPGVSPEDALLIVGKDRRELQTLFQFEGMDIDYGKNGSRFS
HHHHHHHHHHHCCCEEECCCCCCCCCCEEEEECCCHHHHHHHHHHCCCCCCCCCCCCEEE
IGNWDVHGFKKVYTKWHKKLYGKAWNSIYLMNHDQPRAVSRFGDDKKYRKESAKMLATFL
CCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHCCCCHHHHHHHHHHHHHHH
LSMWGTPYIYQGEEIGMTNCPFEGVEEFRDIEMINYYNEQISKGKTKEEIMPGLLYRGRD
HHHCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCHHHCCCCC
NSRTPIQWNDSRNAVFSDAEETWIKVNPNYTEINVEEAEKDPDSILHYFRRMIKTRKDND
CCCCCEEECCCCCCEECCCCCCEEEECCCEEEEEHHHHCCCHHHHHHHHHHHHHCCCCCC
VLIYGDYELVDEGNDDVYAYRRFLDNEEMLVLLNFTDKETSCDVSPYNLEDKELIISNYK
EEEECCEEEECCCCCHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCCCEEEEECCC
GGQKVKGTEVTLRPYEARIYKIK
CCCEECCCEEEEEECEEEEEEEC
>Mature Secondary Structure 
TKKEKSWWKEAVVYQVYPRSFNDTTGNGIGDLRGIIEKLDYIKDLGVDVIWLNPVYESP
CCCHHHHHHHCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCC
CDDMGYDISNYRKILPQFGTMEDFDLLLSEMHKRGLKLVMDLVVNHTSDEHRWFVESRKS
CCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCC
KDNPYRDYYIWKKPKADGSPPNNWVSYFGGSAWEYDEQTGEYYLHLFSKKQPDLNWENPK
CCCCCCCEEEEECCCCCCCCCHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCH
VREEVKDIMRFWLDKGVDGFRMDVIGFISKDPDFEDFPTDNPSGKDLGDKYANGPRLHEF
HHHHHHHHHHHHHHCCCCCEEEHHHHHHCCCCCCCCCCCCCCCCCCCCHHHCCCHHHHHH
LQELHDDVLSHYDCMTVGECPGVSPEDALLIVGKDRRELQTLFQFEGMDIDYGKNGSRFS
HHHHHHHHHHHCCCEEECCCCCCCCCCEEEEECCCHHHHHHHHHHCCCCCCCCCCCCEEE
IGNWDVHGFKKVYTKWHKKLYGKAWNSIYLMNHDQPRAVSRFGDDKKYRKESAKMLATFL
CCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHCCCCHHHHHHHHHHHHHHH
LSMWGTPYIYQGEEIGMTNCPFEGVEEFRDIEMINYYNEQISKGKTKEEIMPGLLYRGRD
HHHCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCHHHCCCCC
NSRTPIQWNDSRNAVFSDAEETWIKVNPNYTEINVEEAEKDPDSILHYFRRMIKTRKDND
CCCCCEEECCCCCCEECCCCCCEEEECCCEEEEEHHHHCCCHHHHHHHHHHHHHCCCCCC
VLIYGDYELVDEGNDDVYAYRRFLDNEEMLVLLNFTDKETSCDVSPYNLEDKELIISNYK
EEEECCEEEECCCCCHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCCCEEEEECCC
GGQKVKGTEVTLRPYEARIYKIK
CCCEECCCEEEEEECEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1761534 [H]