Click here to switch to the map view.

The map label for this gene is dinB [H]

Identifier: 220931742

GI number: 220931742

Start: 970485

End: 971642

Strand: Direct

Name: dinB [H]

Synonym: Hore_08990

Alternate gene names: 220931742

Gene position: 970485-971642 (Clockwise)

Preceding gene: 220931741

Following gene: 220931743

Centisome position: 37.64

GC content: 37.22

Gene sequence:

>1158_bases
ATGGAATTGGATATTATGCATGTAGATATGGATGCCTTTTTTGCCTCTGTGGAACAGCTCGACAATCCTGAATTTAGAAG
GAAACCGGTCATTGTAGGTGGAATAGATTTGGAAAATCGCGGTGTGGTATCCACTGCTTCATACGAAGCCCGCAAATACG
GGGTAAAGTCTGCTATGTCAGTGGTAGAGGCCAGGCGGCTTTGCCCTGAAGGTATTTTTGTAAAAGGGAGGCATAGCAGG
TACCGGGAAATTTCAGAAAAAATATTCAGGATATTTAATACTTATACTCCTCTGGTGGAGAAGGTTTCTATAGATGAAGC
CTTTCTTGATTTAACAGGCTGTCATCGCCTCTTTGGTTCTTCTGTTGAAATTGGTAAAAAAATAAAGAACAAAATAAAAG
AGCAGCTCGGATTAACTGCTTCCATTGGTTTGTCATATAATAAGTTTCTGGCCAAGCTTGCATCTGGAATGGATAAACCA
GATGGCTTTTTTATCATTGATGATAATAATGTAGACAAAATTCTCAACAAATTATGTGTTGGTGAGGTCTGGGGGATAGG
AAAAAAGACAGAGCAATTACTTTTAAGTAAAGGGATAAAAACAGTTGGTATGTTAAGGCATTTATCTAAATCAGATTTAA
AAGGTATACTGGGAAAACAGGGACTTCAACTATATTATCTGGCCAGAGGAATTGATGACCGTCATGTGGAGCCTGGAAGT
GATATAAAATCAATAAGCCATGAAGAAACTTTCAGTGATGACCTTATAGACCCTGATGAGGTTATGTCCCATTTGATGAA
TATGTCGGAACGTGTGGCGCGTCGTTTAAGAAAAAACTGCTTGAAAGGGAGTACAGTATTTATTAAGGTAAGATATAATA
ACAGGGTTACCCTGACTCGCCGAACTACCATAAAGGAGTATGTTGATGATACAGATAGTATTTATAGGACAGGTTTATTA
TTAATTAAAAAACACAACTTATTAAGTAAACCCATAAGGCTTCTGGGAATAGGTATGGCTAATCTTACCGACAATAATGG
CATTCAGTTATCATTATTTACTGACAGAGTAAGGAAAAAAAGGCTTACTTCTACTATCGATAAAATAAAAGATCGTTATG
GAGAAAAGAGTATTACCAGAGGTCGAAATCTGACATAA

Upstream 100 bases:

>100_bases
AGCAACCGGTCTTAACTACCCTGATTTAATAGATAAATTAATAGAACTTGCCCTGGAGGACAGATAGGTTTAGGCCAAAA
CAAACCAGGGGGCGACAAAC

Downstream 100 bases:

>100_bases
TTTTAATATTATATTTAAACCTAATAGTTAAGATTTTGTTAGAGTGTCCCTTCCGGGCGCTCTTTTTTATTTTTGTTTGT
TTCGTTTAAATATTTTAAGC

Product: DNA-directed DNA polymerase

Products: NA

Alternate protein names: Pol IV [H]

Number of amino acids: Translated: 385; Mature: 385

Protein sequence:

>385_residues
MELDIMHVDMDAFFASVEQLDNPEFRRKPVIVGGIDLENRGVVSTASYEARKYGVKSAMSVVEARRLCPEGIFVKGRHSR
YREISEKIFRIFNTYTPLVEKVSIDEAFLDLTGCHRLFGSSVEIGKKIKNKIKEQLGLTASIGLSYNKFLAKLASGMDKP
DGFFIIDDNNVDKILNKLCVGEVWGIGKKTEQLLLSKGIKTVGMLRHLSKSDLKGILGKQGLQLYYLARGIDDRHVEPGS
DIKSISHEETFSDDLIDPDEVMSHLMNMSERVARRLRKNCLKGSTVFIKVRYNNRVTLTRRTTIKEYVDDTDSIYRTGLL
LIKKHNLLSKPIRLLGIGMANLTDNNGIQLSLFTDRVRKKRLTSTIDKIKDRYGEKSITRGRNLT

Sequences:

>Translated_385_residues
MELDIMHVDMDAFFASVEQLDNPEFRRKPVIVGGIDLENRGVVSTASYEARKYGVKSAMSVVEARRLCPEGIFVKGRHSR
YREISEKIFRIFNTYTPLVEKVSIDEAFLDLTGCHRLFGSSVEIGKKIKNKIKEQLGLTASIGLSYNKFLAKLASGMDKP
DGFFIIDDNNVDKILNKLCVGEVWGIGKKTEQLLLSKGIKTVGMLRHLSKSDLKGILGKQGLQLYYLARGIDDRHVEPGS
DIKSISHEETFSDDLIDPDEVMSHLMNMSERVARRLRKNCLKGSTVFIKVRYNNRVTLTRRTTIKEYVDDTDSIYRTGLL
LIKKHNLLSKPIRLLGIGMANLTDNNGIQLSLFTDRVRKKRLTSTIDKIKDRYGEKSITRGRNLT
>Mature_385_residues
MELDIMHVDMDAFFASVEQLDNPEFRRKPVIVGGIDLENRGVVSTASYEARKYGVKSAMSVVEARRLCPEGIFVKGRHSR
YREISEKIFRIFNTYTPLVEKVSIDEAFLDLTGCHRLFGSSVEIGKKIKNKIKEQLGLTASIGLSYNKFLAKLASGMDKP
DGFFIIDDNNVDKILNKLCVGEVWGIGKKTEQLLLSKGIKTVGMLRHLSKSDLKGILGKQGLQLYYLARGIDDRHVEPGS
DIKSISHEETFSDDLIDPDEVMSHLMNMSERVARRLRKNCLKGSTVFIKVRYNNRVTLTRRTTIKEYVDDTDSIYRTGLL
LIKKHNLLSKPIRLLGIGMANLTDNNGIQLSLFTDRVRKKRLTSTIDKIKDRYGEKSITRGRNLT

Specific function: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Homo sapiens, GI84043967, Length=341, Percent_Identity=29.6187683284457, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI7706681, Length=342, Percent_Identity=29.5321637426901, Blast_Score=149, Evalue=3e-36,
Organism=Homo sapiens, GI154350220, Length=314, Percent_Identity=31.5286624203822, Blast_Score=131, Evalue=1e-30,
Organism=Homo sapiens, GI7705344, Length=108, Percent_Identity=42.5925925925926, Blast_Score=102, Evalue=6e-22,
Organism=Homo sapiens, GI5729982, Length=349, Percent_Identity=24.6418338108883, Blast_Score=93, Evalue=5e-19,
Organism=Escherichia coli, GI1786425, Length=277, Percent_Identity=40.7942238267148, Blast_Score=193, Evalue=1e-50,
Organism=Escherichia coli, GI1787432, Length=404, Percent_Identity=25.2475247524752, Blast_Score=92, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI193205700, Length=404, Percent_Identity=29.2079207920792, Blast_Score=139, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI17537959, Length=191, Percent_Identity=29.3193717277487, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI115534089, Length=122, Percent_Identity=42.6229508196721, Blast_Score=91, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI193205702, Length=238, Percent_Identity=30.672268907563, Blast_Score=80, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6324921, Length=258, Percent_Identity=28.2945736434109, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI21355641, Length=283, Percent_Identity=30.0353356890459, Blast_Score=137, Evalue=1e-32,
Organism=Drosophila melanogaster, GI24644984, Length=283, Percent_Identity=30.0353356890459, Blast_Score=137, Evalue=1e-32,
Organism=Drosophila melanogaster, GI19923006, Length=413, Percent_Identity=25.181598062954, Blast_Score=122, Evalue=5e-28,
Organism=Drosophila melanogaster, GI24668444, Length=462, Percent_Identity=24.2424242424242, Blast_Score=85, Evalue=9e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963
- InterPro:   IPR022880 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 43664; Mature: 43664

Theoretical pI: Translated: 10.13; Mature: 10.13

Prosite motif: PS50173 UMUC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELDIMHVDMDAFFASVEQLDNPEFRRKPVIVGGIDLENRGVVSTASYEARKYGVKSAMS
CCEEEEEECHHHHHHHHHHCCCCCHHCCCEEEECCEECCCCCEEECCHHHHHHHHHHHHH
VVEARRLCPEGIFVKGRHSRYREISEKIFRIFNTYTPLVEKVSIDEAFLDLTGCHRLFGS
HHHHHHHCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SVEIGKKIKNKIKEQLGLTASIGLSYNKFLAKLASGMDKPDGFFIIDDNNVDKILNKLCV
CHHHHHHHHHHHHHHHCCEEEECCCHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHH
GEVWGIGKKTEQLLLSKGIKTVGMLRHLSKSDLKGILGKQGLQLYYLARGIDDRHVEPGS
HHHHCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCC
DIKSISHEETFSDDLIDPDEVMSHLMNMSERVARRLRKNCLKGSTVFIKVRYNNRVTLTR
HHHHCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCEEEEEE
RTTIKEYVDDTDSIYRTGLLLIKKHNLLSKPIRLLGIGMANLTDNNGIQLSLFTDRVRKK
HHHHHHHHCCHHHHHHHHHHEEECCHHHHCCHHHHCCCHHCCCCCCCEEEEEEHHHHHHH
RLTSTIDKIKDRYGEKSITRGRNLT
HHHHHHHHHHHHHCCHHHCCCCCCC
>Mature Secondary Structure
MELDIMHVDMDAFFASVEQLDNPEFRRKPVIVGGIDLENRGVVSTASYEARKYGVKSAMS
CCEEEEEECHHHHHHHHHHCCCCCHHCCCEEEECCEECCCCCEEECCHHHHHHHHHHHHH
VVEARRLCPEGIFVKGRHSRYREISEKIFRIFNTYTPLVEKVSIDEAFLDLTGCHRLFGS
HHHHHHHCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SVEIGKKIKNKIKEQLGLTASIGLSYNKFLAKLASGMDKPDGFFIIDDNNVDKILNKLCV
CHHHHHHHHHHHHHHHCCEEEECCCHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHH
GEVWGIGKKTEQLLLSKGIKTVGMLRHLSKSDLKGILGKQGLQLYYLARGIDDRHVEPGS
HHHHCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCC
DIKSISHEETFSDDLIDPDEVMSHLMNMSERVARRLRKNCLKGSTVFIKVRYNNRVTLTR
HHHHCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCEEEEEE
RTTIKEYVDDTDSIYRTGLLLIKKHNLLSKPIRLLGIGMANLTDNNGIQLSLFTDRVRKK
HHHHHHHHCCHHHHHHHHHHEEECCHHHHCCHHHHCCCHHCCCCCCCEEEEEEHHHHHHH
RLTSTIDKIKDRYGEKSITRGRNLT
HHHHHHHHHHHHHCCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA