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The map label for this gene is dapG [H]

Identifier: 220931711

GI number: 220931711

Start: 934866

End: 936071

Strand: Direct

Name: dapG [H]

Synonym: Hore_08680

Alternate gene names: 220931711

Gene position: 934866-936071 (Clockwise)

Preceding gene: 220931710

Following gene: 220931712

Centisome position: 36.26

GC content: 40.05

Gene sequence:

>1206_bases
ATGAAGATAATTGTACAGAAATTTGGTGGTACCTCTTTAGATACACAGGAAAAGAGAGAAATTGCAGCCAGACATATTAA
GTCAGCTGTGGAAAGAGGAAATTATCCGGTAGTTGTTGTTTCGGCCATGGGTAGAAAAGGTGACCCCTATGCTACCGATA
CCTTAATAAATATGGTCTACCGGGTGTCTGAAGATATTGACCCCCGTGAAAAAGATATGCTAATGTCCTGTGGAGAAGTT
ATTTCTGCGGTTGTAATGGTGCAAACCCTGTCGTCATTTGGTTTAAAGGCAAGGGCTTTAACCGGTGCTCAGGCCGGTAT
AGTAACTGATAATAATTTTGGAGACTCGTCAGTAATAAAAGTGAATCCAGAAAAAATAATGGAACTTATCAATAGTAATA
TTATCCCGGTTATCGCCGGTTTTCAGGGGGTTAATATGGACGGGGAAATTACCACCCTGGGACGTGGTGGTAGTGATACG
ACAGCGAGTGTTATCGGCGCAGCCATTAATGCCTCTTTTATTGAAATCTTTACAGATGTTGAAGGGGTCATGACTGCAGA
TCCAAGCATGGTAGATAAGGCCAAAATACTTGATAAGGTAAGTTATAACGAAGTCTGTGAACTTGCCTATCAGGGGGCCC
GGGTTCTCCATCCCAGAGCAGCTGAGATAGCAATGAGAGAAGGAATACCAATCAGGGTAAGGTCTATATTCAATGAAAAC
CCAGGTACCATAATCCAGAATGGTTATAAGGGAATAAAAGGTGATCGTCCCGTTACTGCCGTTACCAGCCGTCGTAATAT
TATTTTCGTCAGGGTTATTCCCAGAAAGGTTGCTGAATATGCTAACGGACTGGCTGTTTTCAAGGTTTTGTCAAAAAACG
GGATTAGTGTTGATTTTATCAATATAAGACCGGAAGCTATTTCATTTATTATTGTTGATGAATTAGAAGATAAGGTTAAA
AAAATTTTATCTGATAACAATTTCAATTTTGAAATAGCAGATGATTTTGCCAAAGTATCAGTGGTGGGTGGTGGAATGAC
GGGAAGACCTGGTGTCATGGCAAGAATTGTTGAGGCTTTATCCAGGGAAAATATCTCGATATACCAGACAACTGATTCCC
ATACTACTATTTCATGTCTGGTTAAAAAACAGGAAGAAAAAAAGGCTTTGAATGCATTGCATTCTGCCTTTAAACTGGAA
GAATAA

Upstream 100 bases:

>100_bases
AGGGGCAGCTTTAAATGCTGTCCAGATTGCGGAAGAACTTATTAAATAGCTTTGTTTGTAGATTCCTTCCGGTTTTTAGC
AGGTTACAGGGAGGTTGTTT

Downstream 100 bases:

>100_bases
TATAGTCTGGAGGGATAAAATGGCTAAAGATTTTGGGGAAGTTTTAACTGCCATGGTTACACCCCTTGATGCCGGGAATG
CTGTAGATTATAGCCAGGCC

Product: aspartate kinase

Products: NA

Alternate protein names: Aspartate kinase 1; Aspartokinase I [H]

Number of amino acids: Translated: 401; Mature: 401

Protein sequence:

>401_residues
MKIIVQKFGGTSLDTQEKREIAARHIKSAVERGNYPVVVVSAMGRKGDPYATDTLINMVYRVSEDIDPREKDMLMSCGEV
ISAVVMVQTLSSFGLKARALTGAQAGIVTDNNFGDSSVIKVNPEKIMELINSNIIPVIAGFQGVNMDGEITTLGRGGSDT
TASVIGAAINASFIEIFTDVEGVMTADPSMVDKAKILDKVSYNEVCELAYQGARVLHPRAAEIAMREGIPIRVRSIFNEN
PGTIIQNGYKGIKGDRPVTAVTSRRNIIFVRVIPRKVAEYANGLAVFKVLSKNGISVDFINIRPEAISFIIVDELEDKVK
KILSDNNFNFEIADDFAKVSVVGGGMTGRPGVMARIVEALSRENISIYQTTDSHTTISCLVKKQEEKKALNALHSAFKLE
E

Sequences:

>Translated_401_residues
MKIIVQKFGGTSLDTQEKREIAARHIKSAVERGNYPVVVVSAMGRKGDPYATDTLINMVYRVSEDIDPREKDMLMSCGEV
ISAVVMVQTLSSFGLKARALTGAQAGIVTDNNFGDSSVIKVNPEKIMELINSNIIPVIAGFQGVNMDGEITTLGRGGSDT
TASVIGAAINASFIEIFTDVEGVMTADPSMVDKAKILDKVSYNEVCELAYQGARVLHPRAAEIAMREGIPIRVRSIFNEN
PGTIIQNGYKGIKGDRPVTAVTSRRNIIFVRVIPRKVAEYANGLAVFKVLSKNGISVDFINIRPEAISFIIVDELEDKVK
KILSDNNFNFEIADDFAKVSVVGGGMTGRPGVMARIVEALSRENISIYQTTDSHTTISCLVKKQEEKKALNALHSAFKLE
E
>Mature_401_residues
MKIIVQKFGGTSLDTQEKREIAARHIKSAVERGNYPVVVVSAMGRKGDPYATDTLINMVYRVSEDIDPREKDMLMSCGEV
ISAVVMVQTLSSFGLKARALTGAQAGIVTDNNFGDSSVIKVNPEKIMELINSNIIPVIAGFQGVNMDGEITTLGRGGSDT
TASVIGAAINASFIEIFTDVEGVMTADPSMVDKAKILDKVSYNEVCELAYQGARVLHPRAAEIAMREGIPIRVRSIFNEN
PGTIIQNGYKGIKGDRPVTAVTSRRNIIFVRVIPRKVAEYANGLAVFKVLSKNGISVDFINIRPEAISFIIVDELEDKVK
KILSDNNFNFEIADDFAKVSVVGGGMTGRPGVMARIVEALSRENISIYQTTDSHTTISCLVKKQEEKKALNALHSAFKLE
E

Specific function: Catalyzes 2 nonconsecutive reactions in the common biosynthetic pathway leading from Asp to diaminopimelate and Lys, to Met, and to Thr and Ile. [C]

COG id: COG0527

COG function: function code E; Aspartokinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartokinase family [H]

Homologues:

Organism=Escherichia coli, GI1786183, Length=273, Percent_Identity=31.1355311355311, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1790455, Length=394, Percent_Identity=26.6497461928934, Blast_Score=105, Evalue=7e-24,
Organism=Escherichia coli, GI1790376, Length=342, Percent_Identity=26.3157894736842, Blast_Score=82, Evalue=8e-17,
Organism=Saccharomyces cerevisiae, GI6320893, Length=378, Percent_Identity=27.7777777777778, Blast_Score=138, Evalue=2e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001048
- InterPro:   IPR005260
- InterPro:   IPR001341
- InterPro:   IPR018042 [H]

Pfam domain/function: PF00696 AA_kinase [H]

EC number: =2.7.2.4 [H]

Molecular weight: Translated: 43635; Mature: 43635

Theoretical pI: Translated: 6.95; Mature: 6.95

Prosite motif: PS00324 ASPARTOKINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIIVQKFGGTSLDTQEKREIAARHIKSAVERGNYPVVVVSAMGRKGDPYATDTLINMVY
CEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHH
RVSEDIDPREKDMLMSCGEVISAVVMVQTLSSFGLKARALTGAQAGIVTDNNFGDSSVIK
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCEEECCCCCCCCEEE
VNPEKIMELINSNIIPVIAGFQGVNMDGEITTLGRGGSDTTASVIGAAINASFIEIFTDV
ECHHHHHHHHCCCCEEEEECCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHCC
EGVMTADPSMVDKAKILDKVSYNEVCELAYQGARVLHPRAAEIAMREGIPIRVRSIFNEN
CCCEECCCHHHHHHHHHHHCCHHHHHHHHHCCCCEECCCHHHHHHHCCCCEEEHHHHCCC
PGTIIQNGYKGIKGDRPVTAVTSRRNIIFVRVIPRKVAEYANGLAVFKVLSKNGISVDFI
CCCEEECCCCCCCCCCCEEEEECCCCEEEEEECHHHHHHHHCCCEEEHHHHCCCCEEEEE
NIRPEAISFIIVDELEDKVKKILSDNNFNFEIADDFAKVSVVGGGMTGRPGVMARIVEAL
EECCCCEEEEEEHHHHHHHHHHHCCCCCCEEEECCCEEEEEEECCCCCCCHHHHHHHHHH
SRENISIYQTTDSHTTISCLVKKQEEKKALNALHSAFKLEE
CCCCEEEEEECCCCCEEEHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKIIVQKFGGTSLDTQEKREIAARHIKSAVERGNYPVVVVSAMGRKGDPYATDTLINMVY
CEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHH
RVSEDIDPREKDMLMSCGEVISAVVMVQTLSSFGLKARALTGAQAGIVTDNNFGDSSVIK
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCEEECCCCCCCCEEE
VNPEKIMELINSNIIPVIAGFQGVNMDGEITTLGRGGSDTTASVIGAAINASFIEIFTDV
ECHHHHHHHHCCCCEEEEECCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHCC
EGVMTADPSMVDKAKILDKVSYNEVCELAYQGARVLHPRAAEIAMREGIPIRVRSIFNEN
CCCEECCCHHHHHHHHHHHCCHHHHHHHHHCCCCEECCCHHHHHHHCCCCEEEHHHHCCC
PGTIIQNGYKGIKGDRPVTAVTSRRNIIFVRVIPRKVAEYANGLAVFKVLSKNGISVDFI
CCCEEECCCCCCCCCCCEEEEECCCCEEEEEECHHHHHHHHCCCEEEHHHHCCCCEEEEE
NIRPEAISFIIVDELEDKVKKILSDNNFNFEIADDFAKVSVVGGGMTGRPGVMARIVEAL
EECCCCEEEEEEHHHHHHHHHHHCCCCCCEEEECCCEEEEEEECCCCCCCHHHHHHHHHH
SRENISIYQTTDSHTTISCLVKKQEEKKALNALHSAFKLEE
CCCCEEEEEECCCCCEEEHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8098035; 9384377 [H]