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The map label for this gene is asd [H]

Identifier: 220931710

GI number: 220931710

Start: 933759

End: 934814

Strand: Direct

Name: asd [H]

Synonym: Hore_08670

Alternate gene names: 220931710

Gene position: 933759-934814 (Clockwise)

Preceding gene: 220931709

Following gene: 220931711

Centisome position: 36.22

GC content: 36.93

Gene sequence:

>1056_bases
ATGAATAATTATGGTAAAATGAATATAGTTATATTTGAACTGGAGGGGAGTAATTTGAGTAGTTATAATATTGCAGTTGT
TGGAGCAACTGGTGCTGTTGGAAGAGAAATGGTTAAGGTACTGGAGCAACGTAATTTTCCGGTAAATAAGTTAAAACTTC
TGGCAACCGAACGGTCAGCCGGAACCAGAATAAATTTTAAGGGTGAAACTATTGAAGTCCAGGTGACCAGGGAAGGTGTC
TTTAAGGATGTAGATATTGCCCTTTTCAGTGCCGGTAGTGGACCGAGTAAAAAAATTGCCCCACTGGCAGTAAAAGAAGG
GGCGGTAGTTATTGATAATAGCAATGCCTTTAGAATGGATAAGAGAGTACCCCTGGTAGTACCAGAGATTAATCCTGAAA
AGATTTTTGAACATGAAGGAATAATTGCTAACCCCAATTGTTCTACCATACAAATGGTTGTTGCCTTAAAACCGATTTAT
GATACTGTAGGTATAGAACGTATCATAGTTAGCACCTATCAGGCTGTATCCGGTACCGGGAAAAAGGCGATTGAAGAACT
AAAAAAACAGGTGAAAGAGTATATAAAAGGAAAAGATATTGAGTCATCTGTATATCCATACCAGATTGCATTTAATGTCT
TACCACATATTGATATCTTTAAGGAAAATGGGTATACCCAGGAAGAAATGAAAATGGTTAACGAGACAAGGAAAATACTG
AATGATCCAGATTTGAAAGTATCGGCAACAGCTGCCAGAGTACCTGTTTTTTACGGACATTCAGAATCTGTTAATGTTCA
AACAAAAGAAAAAATTACAGTCGATGAGGCTAAAAGAATATTAAATAAAGCTTCCGGGATAAAGGTTGTAGATGAACCTG
GAAGGCTATTATATCCTCTACCTCTAATGTCTGAAGATGATGATAATGTACTGGTCGGAAGAATTAGGGAAGATTTATCA
CATGAATTGGGTCTTAATATGTGGATTGTTGCCAATAATTTAAGAAAAGGGGCAGCTTTAAATGCTGTCCAGATTGCGGA
AGAACTTATTAAATAG

Upstream 100 bases:

>100_bases
AGCCAGATTTGATCTTGTTACCAGGGCAGCAGAATTTGCCCTGGAGAAAAAACAAATTCAACCTGTTTTAATAGAATACC
GGGGAATTTAGTTTGCTTTT

Downstream 100 bases:

>100_bases
CTTTGTTTGTAGATTCCTTCCGGTTTTTAGCAGGTTACAGGGAGGTTGTTTATGAAGATAATTGTACAGAAATTTGGTGG
TACCTCTTTAGATACACAGG

Product: aspartate-semialdehyde dehydrogenase

Products: NA

Alternate protein names: ASA dehydrogenase; ASADH [H]

Number of amino acids: Translated: 351; Mature: 351

Protein sequence:

>351_residues
MNNYGKMNIVIFELEGSNLSSYNIAVVGATGAVGREMVKVLEQRNFPVNKLKLLATERSAGTRINFKGETIEVQVTREGV
FKDVDIALFSAGSGPSKKIAPLAVKEGAVVIDNSNAFRMDKRVPLVVPEINPEKIFEHEGIIANPNCSTIQMVVALKPIY
DTVGIERIIVSTYQAVSGTGKKAIEELKKQVKEYIKGKDIESSVYPYQIAFNVLPHIDIFKENGYTQEEMKMVNETRKIL
NDPDLKVSATAARVPVFYGHSESVNVQTKEKITVDEAKRILNKASGIKVVDEPGRLLYPLPLMSEDDDNVLVGRIREDLS
HELGLNMWIVANNLRKGAALNAVQIAEELIK

Sequences:

>Translated_351_residues
MNNYGKMNIVIFELEGSNLSSYNIAVVGATGAVGREMVKVLEQRNFPVNKLKLLATERSAGTRINFKGETIEVQVTREGV
FKDVDIALFSAGSGPSKKIAPLAVKEGAVVIDNSNAFRMDKRVPLVVPEINPEKIFEHEGIIANPNCSTIQMVVALKPIY
DTVGIERIIVSTYQAVSGTGKKAIEELKKQVKEYIKGKDIESSVYPYQIAFNVLPHIDIFKENGYTQEEMKMVNETRKIL
NDPDLKVSATAARVPVFYGHSESVNVQTKEKITVDEAKRILNKASGIKVVDEPGRLLYPLPLMSEDDDNVLVGRIREDLS
HELGLNMWIVANNLRKGAALNAVQIAEELIK
>Mature_351_residues
MNNYGKMNIVIFELEGSNLSSYNIAVVGATGAVGREMVKVLEQRNFPVNKLKLLATERSAGTRINFKGETIEVQVTREGV
FKDVDIALFSAGSGPSKKIAPLAVKEGAVVIDNSNAFRMDKRVPLVVPEINPEKIFEHEGIIANPNCSTIQMVVALKPIY
DTVGIERIIVSTYQAVSGTGKKAIEELKKQVKEYIKGKDIESSVYPYQIAFNVLPHIDIFKENGYTQEEMKMVNETRKIL
NDPDLKVSATAARVPVFYGHSESVNVQTKEKITVDEAKRILNKASGIKVVDEPGRLLYPLPLMSEDDDNVLVGRIREDLS
HELGLNMWIVANNLRKGAALNAVQIAEELIK

Specific function: Unknown

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1788658, Length=336, Percent_Identity=36.6071428571429, Blast_Score=207, Evalue=6e-55,
Organism=Escherichia coli, GI1789841, Length=294, Percent_Identity=24.1496598639456, Blast_Score=76, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6320362, Length=387, Percent_Identity=28.6821705426357, Blast_Score=103, Evalue=5e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000319
- InterPro:   IPR012080
- InterPro:   IPR005986
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.11 [H]

Molecular weight: Translated: 38853; Mature: 38853

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNYGKMNIVIFELEGSNLSSYNIAVVGATGAVGREMVKVLEQRNFPVNKLKLLATERSA
CCCCCEEEEEEEEEECCCCCCEEEEEEECCCHHHHHHHHHHHHCCCCHHHEEEEEECCCC
GTRINFKGETIEVQVTREGVFKDVDIALFSAGSGPSKKIAPLAVKEGAVVIDNSNAFRMD
CCEEEECCCEEEEEEECCCCCEEEEEEEEECCCCCCCCCCEEEEECCEEEEECCCCEEEC
KRVPLVVPEINPEKIFEHEGIIANPNCSTIQMVVALKPIYDTVGIERIIVSTYQAVSGTG
CCCCEEECCCCHHHHHCCCCEEECCCCCEEEEEEEEHHHHHHHCHHHHHHHHHHHHCCCC
KKAIEELKKQVKEYIKGKDIESSVYPYQIAFNVLPHIDIFKENGYTQEEMKMVNETRKIL
HHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCEEEEECCCCCHHHHHHHHHHHHHH
NDPDLKVSATAARVPVFYGHSESVNVQTKEKITVDEAKRILNKASGIKVVDEPGRLLYPL
CCCCCEEEEEEEECEEEECCCCCCCEECCCEEEHHHHHHHHHHCCCCEEEECCCCEEEEC
PLMSEDDDNVLVGRIREDLSHELGLNMWIVANNLRKGAALNAVQIAEELIK
CCCCCCCCCEEHHHHHHHHHHHHCCEEEEEECCCCCCCCCHHHHHHHHHHC
>Mature Secondary Structure
MNNYGKMNIVIFELEGSNLSSYNIAVVGATGAVGREMVKVLEQRNFPVNKLKLLATERSA
CCCCCEEEEEEEEEECCCCCCEEEEEEECCCHHHHHHHHHHHHCCCCHHHEEEEEECCCC
GTRINFKGETIEVQVTREGVFKDVDIALFSAGSGPSKKIAPLAVKEGAVVIDNSNAFRMD
CCEEEECCCEEEEEEECCCCCEEEEEEEEECCCCCCCCCCEEEEECCEEEEECCCCEEEC
KRVPLVVPEINPEKIFEHEGIIANPNCSTIQMVVALKPIYDTVGIERIIVSTYQAVSGTG
CCCCEEECCCCHHHHHCCCCEEECCCCCEEEEEEEEHHHHHHHCHHHHHHHHHHHHCCCC
KKAIEELKKQVKEYIKGKDIESSVYPYQIAFNVLPHIDIFKENGYTQEEMKMVNETRKIL
HHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCEEEEECCCCCHHHHHHHHHHHHHH
NDPDLKVSATAARVPVFYGHSESVNVQTKEKITVDEAKRILNKASGIKVVDEPGRLLYPL
CCCCCEEEEEEEECEEEECCCCCCCEECCCEEEHHHHHHHHHHCCCCEEEECCCCEEEEC
PLMSEDDDNVLVGRIREDLSHELGLNMWIVANNLRKGAALNAVQIAEELIK
CCCCCCCCCEEHHHHHHHHHHHHCCEEEEEECCCCCCCCCHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]