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The map label for this gene is asnC [H]

Identifier: 220931658

GI number: 220931658

Start: 874622

End: 876013

Strand: Direct

Name: asnC [H]

Synonym: Hore_08140

Alternate gene names: 220931658

Gene position: 874622-876013 (Clockwise)

Preceding gene: 220931657

Following gene: 220931659

Centisome position: 33.92

GC content: 39.15

Gene sequence:

>1392_bases
ATGGATTATTTTGAACGTACCAGAATTAAAAACATATTGGAGAAAAATATTGATAACTATAAAGATGTAATTGTACTGGG
ATGGGTGAGAACCAAGAGAGTTTCTAAAAACATTGCTTTTCTGGAAATCAATGATGGAAGTACGTTAAAGAACCTGCAAA
TAGTTATCCTTCAACCAGATAAATTCCCGCTTGACAGTATTAATACCGGAGCCAGTGTAAAAATTAAAGGTTATCTTGAG
GAAGTTAAGGGTAGAGAACAGAGTATTGAAATGAAGGCTGAGGAAATTACATTAATCGGTGAAGCACCTGTTGATTATCC
CATGCAGAAAAAAAGACATACCTTTGAATTTTTACGGGAAATTGCCCACCTGCGCCCCCGGACCAATACCTTCGGTGTTG
TTAATCGTTTCCGCAGTAAAATGGCATATGCAATCCACAAATTTTTCCAGGATCGTGGCTTTCACTATATCCATTCACCG
ATAATTACGACCGGTGACGCTGAAGGAGCAGGTGAGGTTTTTACAGTTACCACCTTTGACCTGCAAAATCCTCCCTTAAG
CGAAGGTGGAGAAATTGATTTTAGCCAGGATTTTTTTGGGGAAGAAGCCGGGCTTACTGTTAGTGGTCAGCTGGAAGCAG
AATTAATGGCAACTGCTCTCGGGGATGTTTATACCTTCGGGCCTACATTCAGGGCAGAGAATTCAAATACTTCCCGCCAT
GCCTCAGAATTCTGGATGATTGAGCCTGAAATGGCCTTCTGTGATCTTGAGGAAATGATGGACATTATTGAGGAATTTAT
TAAGTTTTTATTTAAATATGCCCTTGATGAATGTCCTGAGGAGATGGAATTTTTTAATAAATGGATTGACAAAGGTCGAA
TAGATATTTTAAAAAAAATTATAGACGCTGAATTTGCCCATATAACTTATACTGAAGCTATAGATATACTGGAAAAATCG
GGTGAGGATTTTGAATTTCCGGTAAAATGGGGTATGGATTTACAGTCGGAACACGAACGGTATTTAACAGAAAAACACTT
TAAAAAACCGGTCATGGTGACTGACTACCCCAAGGATATAAAGGCTTTTTACATGAGGGTTAATGATGATGACAAAACCG
TAAGGGCAGTGGACTGTCTGGTACCCCAGGTTGGAGAAATAATCGGTGGTAGTCAGAGGGAAGAACGGTATGATGTCCTG
CTCAAGAGGATGAAAGAACTTGATATGAATATTGAGAAATACCAGTGGTTTCTGGATATTAGAAAGTATGGAACAGTACC
CCATTCTGGTTTTGGACTGGGATTTGAGAGGCTATTAATGTATATCTCTGGTATGAAGAATATCAGGGATGTTATTCCCT
TTCCCAGAACTCCCGGTAATGCCAAATTTTAA

Upstream 100 bases:

>100_bases
GGTTTGGAGAAGGTATTTATTTCTTTATAAAGAAATATATAATTTGGATGTACATTTTATTTTATAGGATATACTACATA
TTGAAGAAAGGGGAGAAGCC

Downstream 100 bases:

>100_bases
GATATATGAGAGGGGGGTATCCCCTCTCCTTTTTTCAGGAGGTTGGAAATGTTTTATTCAAAGTTTTACAATTTTGTGCT
GATAGCTTTAGTAGTTATAT

Product: asparaginyl-tRNA synthetase

Products: NA

Alternate protein names: Asparagine--tRNA ligase; AsnRS [H]

Number of amino acids: Translated: 463; Mature: 463

Protein sequence:

>463_residues
MDYFERTRIKNILEKNIDNYKDVIVLGWVRTKRVSKNIAFLEINDGSTLKNLQIVILQPDKFPLDSINTGASVKIKGYLE
EVKGREQSIEMKAEEITLIGEAPVDYPMQKKRHTFEFLREIAHLRPRTNTFGVVNRFRSKMAYAIHKFFQDRGFHYIHSP
IITTGDAEGAGEVFTVTTFDLQNPPLSEGGEIDFSQDFFGEEAGLTVSGQLEAELMATALGDVYTFGPTFRAENSNTSRH
ASEFWMIEPEMAFCDLEEMMDIIEEFIKFLFKYALDECPEEMEFFNKWIDKGRIDILKKIIDAEFAHITYTEAIDILEKS
GEDFEFPVKWGMDLQSEHERYLTEKHFKKPVMVTDYPKDIKAFYMRVNDDDKTVRAVDCLVPQVGEIIGGSQREERYDVL
LKRMKELDMNIEKYQWFLDIRKYGTVPHSGFGLGFERLLMYISGMKNIRDVIPFPRTPGNAKF

Sequences:

>Translated_463_residues
MDYFERTRIKNILEKNIDNYKDVIVLGWVRTKRVSKNIAFLEINDGSTLKNLQIVILQPDKFPLDSINTGASVKIKGYLE
EVKGREQSIEMKAEEITLIGEAPVDYPMQKKRHTFEFLREIAHLRPRTNTFGVVNRFRSKMAYAIHKFFQDRGFHYIHSP
IITTGDAEGAGEVFTVTTFDLQNPPLSEGGEIDFSQDFFGEEAGLTVSGQLEAELMATALGDVYTFGPTFRAENSNTSRH
ASEFWMIEPEMAFCDLEEMMDIIEEFIKFLFKYALDECPEEMEFFNKWIDKGRIDILKKIIDAEFAHITYTEAIDILEKS
GEDFEFPVKWGMDLQSEHERYLTEKHFKKPVMVTDYPKDIKAFYMRVNDDDKTVRAVDCLVPQVGEIIGGSQREERYDVL
LKRMKELDMNIEKYQWFLDIRKYGTVPHSGFGLGFERLLMYISGMKNIRDVIPFPRTPGNAKF
>Mature_463_residues
MDYFERTRIKNILEKNIDNYKDVIVLGWVRTKRVSKNIAFLEINDGSTLKNLQIVILQPDKFPLDSINTGASVKIKGYLE
EVKGREQSIEMKAEEITLIGEAPVDYPMQKKRHTFEFLREIAHLRPRTNTFGVVNRFRSKMAYAIHKFFQDRGFHYIHSP
IITTGDAEGAGEVFTVTTFDLQNPPLSEGGEIDFSQDFFGEEAGLTVSGQLEAELMATALGDVYTFGPTFRAENSNTSRH
ASEFWMIEPEMAFCDLEEMMDIIEEFIKFLFKYALDECPEEMEFFNKWIDKGRIDILKKIIDAEFAHITYTEAIDILEKS
GEDFEFPVKWGMDLQSEHERYLTEKHFKKPVMVTDYPKDIKAFYMRVNDDDKTVRAVDCLVPQVGEIIGGSQREERYDVL
LKRMKELDMNIEKYQWFLDIRKYGTVPHSGFGLGFERLLMYISGMKNIRDVIPFPRTPGNAKF

Specific function: Unknown

COG id: COG0017

COG function: function code J; Aspartyl/asparaginyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI226491502, Length=445, Percent_Identity=46.0674157303371, Blast_Score=396, Evalue=1e-110,
Organism=Homo sapiens, GI4758762, Length=455, Percent_Identity=28.5714285714286, Blast_Score=174, Evalue=1e-43,
Organism=Homo sapiens, GI45439306, Length=341, Percent_Identity=28.7390029325513, Blast_Score=119, Evalue=6e-27,
Organism=Escherichia coli, GI1787161, Length=463, Percent_Identity=52.9157667386609, Blast_Score=515, Evalue=1e-147,
Organism=Escherichia coli, GI1788173, Length=109, Percent_Identity=36.697247706422, Blast_Score=68, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17556372, Length=429, Percent_Identity=32.1678321678322, Blast_Score=195, Evalue=5e-50,
Organism=Caenorhabditis elegans, GI71984122, Length=454, Percent_Identity=29.9559471365639, Blast_Score=188, Evalue=6e-48,
Organism=Caenorhabditis elegans, GI17551876, Length=489, Percent_Identity=25.1533742331288, Blast_Score=123, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6319872, Length=488, Percent_Identity=36.4754098360656, Blast_Score=303, Evalue=4e-83,
Organism=Saccharomyces cerevisiae, GI6321807, Length=456, Percent_Identity=30.7017543859649, Blast_Score=190, Evalue=4e-49,
Organism=Saccharomyces cerevisiae, GI6323011, Length=344, Percent_Identity=29.0697674418605, Blast_Score=123, Evalue=7e-29,
Organism=Drosophila melanogaster, GI19922416, Length=471, Percent_Identity=35.244161358811, Blast_Score=267, Evalue=1e-71,
Organism=Drosophila melanogaster, GI19921528, Length=467, Percent_Identity=28.2655246252677, Blast_Score=169, Evalue=4e-42,
Organism=Drosophila melanogaster, GI17136276, Length=473, Percent_Identity=25.369978858351, Blast_Score=115, Evalue=5e-26,

Paralogues:

None

Copy number: 80 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004364
- InterPro:   IPR018150
- InterPro:   IPR006195
- InterPro:   IPR004522
- InterPro:   IPR002312
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF00152 tRNA-synt_2; PF01336 tRNA_anti [H]

EC number: =6.1.1.22 [H]

Molecular weight: Translated: 53765; Mature: 53765

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDYFERTRIKNILEKNIDNYKDVIVLGWVRTKRVSKNIAFLEINDGSTLKNLQIVILQPD
CCHHHHHHHHHHHHHCCCCCCCEEEEEEHHHHHHCCCEEEEEECCCCCCCCEEEEEECCC
KFPLDSINTGASVKIKGYLEEVKGREQSIEMKAEEITLIGEAPVDYPMQKKRHTFEFLRE
CCCCCCCCCCCEEEEHHHHHHHCCCHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHHH
IAHLRPRTNTFGVVNRFRSKMAYAIHKFFQDRGFHYIHSPIITTGDAEGAGEVFTVTTFD
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCEEECCCCCCCCCEEEEEEEE
LQNPPLSEGGEIDFSQDFFGEEAGLTVSGQLEAELMATALGDVYTFGPTFRAENSNTSRH
CCCCCCCCCCCCCCCHHHCCCCCCEEEECCHHHHHHHHHHHHHHCCCCCEECCCCCCCCC
ASEFWMIEPEMAFCDLEEMMDIIEEFIKFLFKYALDECPEEMEFFNKWIDKGRIDILKKI
CCCEEEECCCHHHCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCHHHHHHHH
IDAEFAHITYTEAIDILEKSGEDFEFPVKWGMDLQSEHERYLTEKHFKKPVMVTDYPKDI
HCCHHHHHHHHHHHHHHHCCCCCCCCCHHCCCCCHHHHHHHHHHHHCCCCCEECCCCCCC
KAFYMRVNDDDKTVRAVDCLVPQVGEIIGGSQREERYDVLLKRMKELDMNIEKYQWFLDI
EEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHH
RKYGTVPHSGFGLGFERLLMYISGMKNIRDVIPFPRTPGNAKF
HHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MDYFERTRIKNILEKNIDNYKDVIVLGWVRTKRVSKNIAFLEINDGSTLKNLQIVILQPD
CCHHHHHHHHHHHHHCCCCCCCEEEEEEHHHHHHCCCEEEEEECCCCCCCCEEEEEECCC
KFPLDSINTGASVKIKGYLEEVKGREQSIEMKAEEITLIGEAPVDYPMQKKRHTFEFLRE
CCCCCCCCCCCEEEEHHHHHHHCCCHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHHH
IAHLRPRTNTFGVVNRFRSKMAYAIHKFFQDRGFHYIHSPIITTGDAEGAGEVFTVTTFD
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCEEECCCCCCCCCEEEEEEEE
LQNPPLSEGGEIDFSQDFFGEEAGLTVSGQLEAELMATALGDVYTFGPTFRAENSNTSRH
CCCCCCCCCCCCCCCHHHCCCCCCEEEECCHHHHHHHHHHHHHHCCCCCEECCCCCCCCC
ASEFWMIEPEMAFCDLEEMMDIIEEFIKFLFKYALDECPEEMEFFNKWIDKGRIDILKKI
CCCEEEECCCHHHCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCHHHHHHHH
IDAEFAHITYTEAIDILEKSGEDFEFPVKWGMDLQSEHERYLTEKHFKKPVMVTDYPKDI
HCCHHHHHHHHHHHHHHHCCCCCCCCCHHCCCCCHHHHHHHHHHHHCCCCCEECCCCCCC
KAFYMRVNDDDKTVRAVDCLVPQVGEIIGGSQREERYDVLLKRMKELDMNIEKYQWFLDI
EEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHH
RKYGTVPHSGFGLGFERLLMYISGMKNIRDVIPFPRTPGNAKF
HHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12552129 [H]