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The map label for this gene is glpA [C]

Identifier: 220931654

GI number: 220931654

Start: 870681

End: 872192

Strand: Direct

Name: glpA [C]

Synonym: Hore_08100

Alternate gene names: 220931654

Gene position: 870681-872192 (Clockwise)

Preceding gene: 220931653

Following gene: 220931655

Centisome position: 33.77

GC content: 40.01

Gene sequence:

>1512_bases
ATGAGAGCAGACGTTATTATCATCGGAAGTGGTGTTGTTGGAAGTGCAATTGCCCGGAGACTTGCCAGATATAACCTTGA
TATTATTCTTCTTGAAAAAGAACATGATGTTGCTATGGGTACAAGTAAAGCTAATTCAGGTATTATACATGCCGGTTATA
ATGCACCCTATGATAGTCTTAAAGGTAGATTGAATGTCAAATCAAACCCTGAATTTGATAAACTTTGCAGAGATTTAAGG
GTTCCCTTTAAACGGATTGGTTCCCTGGTAGTTGGCTTTGATGATAAAGACCTGAAAATACTTAAAGAAGAAAAAGAAAA
TGGAGAGAAGGCCGGAATAAAAGACCTGGAGATAGTAAAGGGCAAAAGGCTTTTTGAAATTGAACCAAATTTAAATCCAG
AAGCCATGTATGCCCTGTATGCTCCGACTGCCGGTATTATTTCTCCACACCAATTTACAATTGCCCTTGCTGATAGTGCT
GCCCTCAATGGAGTTAAAGTTATGCTTTTGACAGAAGCCCGGAACATAAAAACTGAAAACGGTATGATTACCGGGGTAGA
AACTAACAGAGGTTTTATTGCTGCTAAAGTAGTTATAAACGCTGCTGGTGTATATGCCGGGAATATTGCCAGTTTAGCCG
GTGATTCGAGTATTTCTATAACCCCGAGGAAAGGTGAGTATCACCTTCTCGATAAAGAATGGGGTGATAAAGTCAATCAC
GTATTGTTCCCTATTCCCAGTACAGTATCAAAAGGAATTCTGGTGACACCTACTGTCCACGGTAACCTCTTAATCGGTCC
TAATTCTTATAATGTTGAAGACCCTGAAGATGTATCAACTACAACATCTGGACTTGACGAGGTTTATAACGGGGCCAGAA
GGCTTGTTCCTTCAATAAATCGAAGGGATGTAATTGCTTCTTTTGCTGGATTAAGGGCTGCAGCCTCAGGAGAAGATTTT
ATCATTGGTTCTTCCAGTCACATTAAGGGGCTTATTCATGCTGCTGGTATCCAGTCACCGGGATTAAGCTCAGCTCCAGC
AATTGCAGAAAAGGTAGAGGAAATTTTTAAAGATATAGCTGATGAGTTTTCCCTTGAGATCAGTTATAAGGATGATTTTA
AGGAAACTCTTCCGGAATACCCCTGTTTTTCAGAAAAACTTGAAAAAAGTCATGAACAGGAGTGGAATAATTTGGTTAGG
GAAAATCCAGATTTTGGTGAAATAGTTTGCCGATGTGAACGGGTAACAAAGGGTGAAATAATTGCAGCTATTCACCGTCC
GGTACCGGCCTTAAGCCTTGATGCTATTAAACGAAGAACGAGGGCAGGAATGGGAAGATGCCAGGGTGGATTTTGTGGAC
ACCGGGTTCTGGAAATACTATCAGAAGAGTTAAATATATCTCCCCTGGAGGTAACAAAAAAAGGCGGGGAATCAAAAATA
TTAATGAGAAAAACAAAAGATACGGAACATCAATATGAACAAATGGAGGTAGGTGTTGGTGAAAATGTATAA

Upstream 100 bases:

>100_bases
AGAGAACCATTATTATTGACCTGGGTGAAGTATGCCTTCATTACATAAAGGTCAGTAAGGTGGTTCTCTTTTTTTATTTA
AACAAAAAGGAGGAATATAG

Downstream 100 bases:

>100_bases
CTATGACCTTGTAGTTGTTGGTGGGGGACCGGCTGGACTGGCAGCAGCCCTGGAGGCATACAAAAATGGTGTAAATAAAG
TCTTACTGCTGGAGAGGGAT

Product: glycerol-3-phosphate dehydrogenase

Products: glycerone phosphate; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 503; Mature: 503

Protein sequence:

>503_residues
MRADVIIIGSGVVGSAIARRLARYNLDIILLEKEHDVAMGTSKANSGIIHAGYNAPYDSLKGRLNVKSNPEFDKLCRDLR
VPFKRIGSLVVGFDDKDLKILKEEKENGEKAGIKDLEIVKGKRLFEIEPNLNPEAMYALYAPTAGIISPHQFTIALADSA
ALNGVKVMLLTEARNIKTENGMITGVETNRGFIAAKVVINAAGVYAGNIASLAGDSSISITPRKGEYHLLDKEWGDKVNH
VLFPIPSTVSKGILVTPTVHGNLLIGPNSYNVEDPEDVSTTTSGLDEVYNGARRLVPSINRRDVIASFAGLRAAASGEDF
IIGSSSHIKGLIHAAGIQSPGLSSAPAIAEKVEEIFKDIADEFSLEISYKDDFKETLPEYPCFSEKLEKSHEQEWNNLVR
ENPDFGEIVCRCERVTKGEIIAAIHRPVPALSLDAIKRRTRAGMGRCQGGFCGHRVLEILSEELNISPLEVTKKGGESKI
LMRKTKDTEHQYEQMEVGVGENV

Sequences:

>Translated_503_residues
MRADVIIIGSGVVGSAIARRLARYNLDIILLEKEHDVAMGTSKANSGIIHAGYNAPYDSLKGRLNVKSNPEFDKLCRDLR
VPFKRIGSLVVGFDDKDLKILKEEKENGEKAGIKDLEIVKGKRLFEIEPNLNPEAMYALYAPTAGIISPHQFTIALADSA
ALNGVKVMLLTEARNIKTENGMITGVETNRGFIAAKVVINAAGVYAGNIASLAGDSSISITPRKGEYHLLDKEWGDKVNH
VLFPIPSTVSKGILVTPTVHGNLLIGPNSYNVEDPEDVSTTTSGLDEVYNGARRLVPSINRRDVIASFAGLRAAASGEDF
IIGSSSHIKGLIHAAGIQSPGLSSAPAIAEKVEEIFKDIADEFSLEISYKDDFKETLPEYPCFSEKLEKSHEQEWNNLVR
ENPDFGEIVCRCERVTKGEIIAAIHRPVPALSLDAIKRRTRAGMGRCQGGFCGHRVLEILSEELNISPLEVTKKGGESKI
LMRKTKDTEHQYEQMEVGVGENV
>Mature_503_residues
MRADVIIIGSGVVGSAIARRLARYNLDIILLEKEHDVAMGTSKANSGIIHAGYNAPYDSLKGRLNVKSNPEFDKLCRDLR
VPFKRIGSLVVGFDDKDLKILKEEKENGEKAGIKDLEIVKGKRLFEIEPNLNPEAMYALYAPTAGIISPHQFTIALADSA
ALNGVKVMLLTEARNIKTENGMITGVETNRGFIAAKVVINAAGVYAGNIASLAGDSSISITPRKGEYHLLDKEWGDKVNH
VLFPIPSTVSKGILVTPTVHGNLLIGPNSYNVEDPEDVSTTTSGLDEVYNGARRLVPSINRRDVIASFAGLRAAASGEDF
IIGSSSHIKGLIHAAGIQSPGLSSAPAIAEKVEEIFKDIADEFSLEISYKDDFKETLPEYPCFSEKLEKSHEQEWNNLVR
ENPDFGEIVCRCERVTKGEIIAAIHRPVPALSLDAIKRRTRAGMGRCQGGFCGHRVLEILSEELNISPLEVTKKGGESKI
LMRKTKDTEHQYEQMEVGVGENV

Specific function: Conversion Of Glycerol 3-Phosphate To Dihydroxyacetone. Uses Fumarate Or Nitrate As Electron Acceptor. [C]

COG id: COG0579

COG function: function code R; Predicted dehydrogenase

Gene ontology:

Cell location: Loosely Bound To The Cytoplasm Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI13376331, Length=404, Percent_Identity=25.4950495049505, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI194306651, Length=361, Percent_Identity=25.207756232687, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI24797151, Length=220, Percent_Identity=28.1818181818182, Blast_Score=67, Evalue=5e-11,
Organism=Escherichia coli, GI1788574, Length=489, Percent_Identity=24.3353783231084, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI87082148, Length=369, Percent_Identity=25.4742547425474, Blast_Score=92, Evalue=8e-20,
Organism=Escherichia coli, GI1787559, Length=219, Percent_Identity=27.8538812785388, Blast_Score=67, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17565764, Length=405, Percent_Identity=27.6543209876543, Blast_Score=126, Evalue=3e-29,
Organism=Drosophila melanogaster, GI24585081, Length=393, Percent_Identity=25.9541984732824, Blast_Score=107, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: 1.1.99.5

Molecular weight: Translated: 54885; Mature: 54885

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRADVIIIGSGVVGSAIARRLARYNLDIILLEKEHDVAMGTSKANSGIIHAGYNAPYDSL
CCCCEEEEECCHHHHHHHHHHHHCCCEEEEEECCCCCEECCCCCCCCEEECCCCCCHHHC
KGRLNVKSNPEFDKLCRDLRVPFKRIGSLVVGFDDKDLKILKEEKENGEKAGIKDLEIVK
CCEEECCCCCCHHHHHHHHCCCHHHCCCEEEECCCCCHHHHHHHHCCCCCCCCCCEEEEC
GKRLFEIEPNLNPEAMYALYAPTAGIISPHQFTIALADSAALNGVKVMLLTEARNIKTEN
CCEEEEECCCCCHHEEEEEECCCCCCCCCCEEEEEEECCCCCCCEEEEEEECCCCCCCCC
GMITGVETNRGFIAAKVVINAAGVYAGNIASLAGDSSISITPRKGEYHLLDKEWGDKVNH
CEEEEEECCCCEEEEEEEEEECCEECCCHHHHCCCCCEEEECCCCCEEECCHHHCCCCCE
VLFPIPSTVSKGILVTPTVHGNLLIGPNSYNVEDPEDVSTTTSGLDEVYNGARRLVPSIN
EEEECCHHHCCCEEEEEEECCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCC
RRDVIASFAGLRAAASGEDFIIGSSSHIKGLIHAAGIQSPGLSSAPAIAEKVEEIFKDIA
HHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHH
DEFSLEISYKDDFKETLPEYPCFSEKLEKSHEQEWNNLVRENPDFGEIVCRCERVTKGEI
HHHEEEEEECCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCE
IAAIHRPVPALSLDAIKRRTRAGMGRCQGGFCGHRVLEILSEELNISPLEVTKKGGESKI
EEEECCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCEEEECCCCCCEE
LMRKTKDTEHQYEQMEVGVGENV
EEECCCCHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MRADVIIIGSGVVGSAIARRLARYNLDIILLEKEHDVAMGTSKANSGIIHAGYNAPYDSL
CCCCEEEEECCHHHHHHHHHHHHCCCEEEEEECCCCCEECCCCCCCCEEECCCCCCHHHC
KGRLNVKSNPEFDKLCRDLRVPFKRIGSLVVGFDDKDLKILKEEKENGEKAGIKDLEIVK
CCEEECCCCCCHHHHHHHHCCCHHHCCCEEEECCCCCHHHHHHHHCCCCCCCCCCEEEEC
GKRLFEIEPNLNPEAMYALYAPTAGIISPHQFTIALADSAALNGVKVMLLTEARNIKTEN
CCEEEEECCCCCHHEEEEEECCCCCCCCCCEEEEEEECCCCCCCEEEEEEECCCCCCCCC
GMITGVETNRGFIAAKVVINAAGVYAGNIASLAGDSSISITPRKGEYHLLDKEWGDKVNH
CEEEEEECCCCEEEEEEEEEECCEECCCHHHHCCCCCEEEECCCCCEEECCHHHCCCCCE
VLFPIPSTVSKGILVTPTVHGNLLIGPNSYNVEDPEDVSTTTSGLDEVYNGARRLVPSIN
EEEECCHHHCCCEEEEEEECCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCC
RRDVIASFAGLRAAASGEDFIIGSSSHIKGLIHAAGIQSPGLSSAPAIAEKVEEIFKDIA
HHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHH
DEFSLEISYKDDFKETLPEYPCFSEKLEKSHEQEWNNLVRENPDFGEIVCRCERVTKGEI
HHHEEEEEECCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCE
IAAIHRPVPALSLDAIKRRTRAGMGRCQGGFCGHRVLEILSEELNISPLEVTKKGGESKI
EEEECCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCEEEECCCCCCEE
LMRKTKDTEHQYEQMEVGVGENV
EEECCCCHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: sn-glycerol 3-phosphate; acceptor

Specific reaction: sn-glycerol 3-phosphate + acceptor = glycerone phosphate + reduced acceptor

General reaction: Redox reaction [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8948633 [H]