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The map label for this gene is tsf

Identifier: 220931610

GI number: 220931610

Start: 823206

End: 824105

Strand: Direct

Name: tsf

Synonym: Hore_07660

Alternate gene names: 220931610

Gene position: 823206-824105 (Clockwise)

Preceding gene: 220931609

Following gene: 220931611

Centisome position: 31.93

GC content: 35.78

Gene sequence:

>900_bases
ATGGGTATTTCCATGAAAGACATAAAGGAATTAAGGTCAAGAACAGGTGCTGGAGTACTTGACTGTAAAAAGGCTCTCGC
TGAAACCAATGGTGATATCGATGCTGCTGTAGAATATCTAAGGGAAAAGGGTATTGCAGCAGCTGCTAAAAAGGCTGGCA
GGGTTGCAGCTGAAGGTGCTGTAAATGTTTACATATCAGATGACCGCAAAAAAGGTGTTATTGTTGAAGTCAATAGTGAA
ACAGACTTTGTTGCCAAGAATGATAATTTTAAAGACCTTGTCAATAAGATTTCTGAACACTTAATGCAAAGTGATGCAAA
CAGTGTTGATGAGGTTCTGAAAGAAACCTGGTATCAAGATAGTGAAAAAGATGTAAATACTATCATAAAAGAAGCGATTG
CCAGTATCGGTGAAAACATTAACCTGAGACGGTTTGAAAAGTATGAAACTAATGGATTCCTCCAGGGATATATTCATATG
GGGGGTAAAATTGGCGTTTTAGTTGACATTGATGGAGAATTTAACGATAGTACCCGAAAAGTGGCTAAAGATATTGCTAT
GCATATTGCTGCCATTAATCCCCGCTATTTGAGCAGAGATGATATTAGTGAAGAAGTAATTAATAAAGAAAAAGAGATAT
ATAAAGAACAGATGTTAAATGAAGGAAAACCTGAACATATTATCGGTCAGATTGTAAAAGGTAAAATGGAAAAATATTAT
AGTGAAGTCTGTCTCCTTGACCAGGCCTTTGTTAGGGATGAAGATATTACTGTAGGTAAATTAATTGAAGACAATGGACT
GAAAATTAACGGTTTTACCCGGTTTGAACTGGGGGAAGGTATTGAAAAAGAGGAAGAAGATTTTGCTGCAGAAGTAATGA
AAGAAGTTAATAAAAAATAA

Upstream 100 bases:

>100_bases
AATAATTCAGCAAATAAAGAGGAATAATAAAGGGAAAAGGCGTTGGTTAGAAGAGTTTTCTTCTACCACGCCTTTTTGTA
CGAAAAAAGGAGGGAAAAAA

Downstream 100 bases:

>100_bases
TATTTATTGGTTAAAAGAGAGCACTTTTAAGGTGTTCTCTTTTTTCAGGTCTTATTTTTTAATATTAAAATTAATAAATT
TGATTAAAGTTTTGTCTTAA

Product: translation elongation factor Ts

Products: NA

Alternate protein names: EF-Ts

Number of amino acids: Translated: 299; Mature: 298

Protein sequence:

>299_residues
MGISMKDIKELRSRTGAGVLDCKKALAETNGDIDAAVEYLREKGIAAAAKKAGRVAAEGAVNVYISDDRKKGVIVEVNSE
TDFVAKNDNFKDLVNKISEHLMQSDANSVDEVLKETWYQDSEKDVNTIIKEAIASIGENINLRRFEKYETNGFLQGYIHM
GGKIGVLVDIDGEFNDSTRKVAKDIAMHIAAINPRYLSRDDISEEVINKEKEIYKEQMLNEGKPEHIIGQIVKGKMEKYY
SEVCLLDQAFVRDEDITVGKLIEDNGLKINGFTRFELGEGIEKEEEDFAAEVMKEVNKK

Sequences:

>Translated_299_residues
MGISMKDIKELRSRTGAGVLDCKKALAETNGDIDAAVEYLREKGIAAAAKKAGRVAAEGAVNVYISDDRKKGVIVEVNSE
TDFVAKNDNFKDLVNKISEHLMQSDANSVDEVLKETWYQDSEKDVNTIIKEAIASIGENINLRRFEKYETNGFLQGYIHM
GGKIGVLVDIDGEFNDSTRKVAKDIAMHIAAINPRYLSRDDISEEVINKEKEIYKEQMLNEGKPEHIIGQIVKGKMEKYY
SEVCLLDQAFVRDEDITVGKLIEDNGLKINGFTRFELGEGIEKEEEDFAAEVMKEVNKK
>Mature_298_residues
GISMKDIKELRSRTGAGVLDCKKALAETNGDIDAAVEYLREKGIAAAAKKAGRVAAEGAVNVYISDDRKKGVIVEVNSET
DFVAKNDNFKDLVNKISEHLMQSDANSVDEVLKETWYQDSEKDVNTIIKEAIASIGENINLRRFEKYETNGFLQGYIHMG
GKIGVLVDIDGEFNDSTRKVAKDIAMHIAAINPRYLSRDDISEEVINKEKEIYKEQMLNEGKPEHIIGQIVKGKMEKYYS
EVCLLDQAFVRDEDITVGKLIEDNGLKINGFTRFELGEGIEKEEEDFAAEVMKEVNKK

Specific function: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome

COG id: COG0264

COG function: function code J; Translation elongation factor Ts

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EF-Ts family

Homologues:

Organism=Homo sapiens, GI171846268, Length=299, Percent_Identity=25.0836120401338, Blast_Score=78, Evalue=8e-15,
Organism=Escherichia coli, GI1786366, Length=290, Percent_Identity=43.1034482758621, Blast_Score=215, Evalue=3e-57,
Organism=Caenorhabditis elegans, GI17561440, Length=302, Percent_Identity=29.4701986754967, Blast_Score=93, Evalue=1e-19,
Organism=Drosophila melanogaster, GI19921466, Length=314, Percent_Identity=27.3885350318471, Blast_Score=99, Evalue=2e-21,

Paralogues:

None

Copy number: 2670 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1100 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). 4173 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 14563 Molecules/Cell In: Growth Phase, Gluco

Swissprot (AC and ID): EFTS_HALOH (B8CW54)

Other databases:

- EMBL:   CP001098
- RefSeq:   YP_002508518.1
- GeneID:   7314753
- GenomeReviews:   CP001098_GR
- KEGG:   hor:Hore_07660
- HOGENOM:   HBG713289
- OMA:   YLHGTRI
- GO:   GO:0005737
- HAMAP:   MF_00050
- InterPro:   IPR001816
- InterPro:   IPR014039
- InterPro:   IPR018101
- InterPro:   IPR009060
- InterPro:   IPR000449
- Gene3D:   G3DSA:3.30.479.20
- PANTHER:   PTHR11741
- TIGRFAMs:   TIGR00116

Pfam domain/function: PF00889 EF_TS; PF00627 UBA; SSF54713 EF_TS; SSF46934 UBA_like

EC number: NA

Molecular weight: Translated: 33508; Mature: 33377

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: PS01126 EF_TS_1; PS01127 EF_TS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGISMKDIKELRSRTGAGVLDCKKALAETNGDIDAAVEYLREKGIAAAAKKAGRVAAEGA
CCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHCCEEECCE
VNVYISDDRKKGVIVEVNSETDFVAKNDNFKDLVNKISEHLMQSDANSVDEVLKETWYQD
EEEEEECCCCCCEEEEECCCCCEEECCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCC
SEKDVNTIIKEAIASIGENINLRRFEKYETNGFLQGYIHMGGKIGVLVDIDGEFNDSTRK
CHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCEEEEEECCCEEEEEEEECCCCCHHHHH
VAKDIAMHIAAINPRYLSRDDISEEVINKEKEIYKEQMLNEGKPEHIIGQIVKGKMEKYY
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
SEVCLLDQAFVRDEDITVGKLIEDNGLKINGFTRFELGEGIEKEEEDFAAEVMKEVNKK
HHHHHHHHHHHCCCCCEEHEEECCCCEEECCEEEECCCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
GISMKDIKELRSRTGAGVLDCKKALAETNGDIDAAVEYLREKGIAAAAKKAGRVAAEGA
CCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHCCEEECCE
VNVYISDDRKKGVIVEVNSETDFVAKNDNFKDLVNKISEHLMQSDANSVDEVLKETWYQD
EEEEEECCCCCCEEEEECCCCCEEECCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCC
SEKDVNTIIKEAIASIGENINLRRFEKYETNGFLQGYIHMGGKIGVLVDIDGEFNDSTRK
CHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCEEEEEECCCEEEEEEEECCCCCHHHHH
VAKDIAMHIAAINPRYLSRDDISEEVINKEKEIYKEQMLNEGKPEHIIGQIVKGKMEKYY
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
SEVCLLDQAFVRDEDITVGKLIEDNGLKINGFTRFELGEGIEKEEEDFAAEVMKEVNKK
HHHHHHHHHHHCCCCCEEHEEECCCCEEECCEEEECCCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA