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The map label for this gene is spoIVB [H]

Identifier: 220931502

GI number: 220931502

Start: 713664

End: 714968

Strand: Direct

Name: spoIVB [H]

Synonym: Hore_06580

Alternate gene names: 220931502

Gene position: 713664-714968 (Clockwise)

Preceding gene: 220931501

Following gene: 220931503

Centisome position: 27.68

GC content: 36.25

Gene sequence:

>1305_bases
TTGAAAAGAAAAATTGGTTTAGGTATTTTTTTTGGTCTTATTTTAATCATATCTTTATTTTATTTTTTTTCTATTAATAC
TTTACCTTCTTCTTTATCTATAATAAAAGGTAATGAGTCAACCTTTAATATTAATTTTCCTTTCAGTTTGCATATTCAAA
AAAGTGGTCGAGGTATTGGATTGAAAATTAATGGTCAGGTACTGGGACAGAAGGAGTTCAGGATAAAAGAAAATCAGCTT
CAGGTTAAAGGAGACAAGGTTGGGTCAACTTCACTTAATGTAAGGCTTTTTGGAATTATCCCTTTAAGAACTATTAATGT
AAATGTTTTACCTGATGTCAAGGTATATCCTGGAGGACAGGCTATTGGAGTTTTATTAAGAAGTAAAGGTGTAATGGTTG
TTGGTAAATCTTTTGTCGAGGGAAAGGATGGTCGCAAATATTATCCTGCAGTCCAGAGTGGTATAGAAGTTGGAGATACT
ATCTTAAAAATTAACGGGATTGAAGTTTATGATAAAGTAAAATTGGCTTCATTAATTCAAAAAATGGCTCCAGGGGGGAA
GCTAACCCTGGAAATCAAAAAAAAGGATGGACGAATAAAAAAGATACCAGTGAATCCTGTTAAAAACAAACAGGGAAAGT
ATATGATAGGTTTATATGTTGATGATGGAGTTGCCGGTGTAGGCACCCTGACATTTTTTGATCCGAAATCAGGGGAATAT
GGAGCTTTAGGACATGTTATTACTGAAACCAACAGTCAGGTCAAAATTGATATCCGACAGGGTAAAATTATTGAAGCCAG
GATTTCTGGCATAAATACAGGAAAAAGGGGTTTGCCTGGAGAAAAACTGGGTACCTTTTTTCAAACAAAACAGATACTTG
GAGAGATCAGAAAAAACACACAGTATGGAATATACGGGAAGTTAAATAGATTACCGGAAAACCCATATTTTAATGAACCT
ATTCCGGTTCTTCCTGCCTCCCAGGTACAGGAGGGTCAGGCCAAGATTTATACTGTTATTAAAGGTGGTAAAATTGAAGA
ATTTGATGTAAGTATAGACAGGGTATACCATCAATCTCACCCTGGTGCAAAAGGAATGATAATAAGGATTACTGATCCTC
AACTAAAAAAAGCAACCGGGGGTATAATCCAGGGAATGAGTGGTAGTCCAATCGTACAGAATAATAAGCTGGTGGGGGCA
ATCACCCATGTGTTTGTAAATGACCCAACCCGGGGTTACGGTGTTTTTGCAGAATGGATGGTATTACAGACAGGGTTATA
TGATAAAGCCAGAGCCGTTCAATAG

Upstream 100 bases:

>100_bases
ATAACCTGCCAAGATATAACTGAATAAACCTCAATTAGCTAGGGCATCTCTAAATATAAGAGATGCCTTATTTATTTCTG
CTGGCAGGAGTGTGATATTA

Downstream 100 bases:

>100_bases
CTCTGGCTTTTTTATTTTAAAAAATAGTCCAAAAGTGGTAATTATTAGCTAAATAGGATTATTCTTTAACATTAAAGGAA
AGTTATAGTTAATTTTAAAA

Product: Peptidase S55 sporulation stage IV protein B

Products: NA

Alternate protein names: Sporulation factor IV B protease; Stage IV sporulation protein B [H]

Number of amino acids: Translated: 434; Mature: 434

Protein sequence:

>434_residues
MKRKIGLGIFFGLILIISLFYFFSINTLPSSLSIIKGNESTFNINFPFSLHIQKSGRGIGLKINGQVLGQKEFRIKENQL
QVKGDKVGSTSLNVRLFGIIPLRTINVNVLPDVKVYPGGQAIGVLLRSKGVMVVGKSFVEGKDGRKYYPAVQSGIEVGDT
ILKINGIEVYDKVKLASLIQKMAPGGKLTLEIKKKDGRIKKIPVNPVKNKQGKYMIGLYVDDGVAGVGTLTFFDPKSGEY
GALGHVITETNSQVKIDIRQGKIIEARISGINTGKRGLPGEKLGTFFQTKQILGEIRKNTQYGIYGKLNRLPENPYFNEP
IPVLPASQVQEGQAKIYTVIKGGKIEEFDVSIDRVYHQSHPGAKGMIIRITDPQLKKATGGIIQGMSGSPIVQNNKLVGA
ITHVFVNDPTRGYGVFAEWMVLQTGLYDKARAVQ

Sequences:

>Translated_434_residues
MKRKIGLGIFFGLILIISLFYFFSINTLPSSLSIIKGNESTFNINFPFSLHIQKSGRGIGLKINGQVLGQKEFRIKENQL
QVKGDKVGSTSLNVRLFGIIPLRTINVNVLPDVKVYPGGQAIGVLLRSKGVMVVGKSFVEGKDGRKYYPAVQSGIEVGDT
ILKINGIEVYDKVKLASLIQKMAPGGKLTLEIKKKDGRIKKIPVNPVKNKQGKYMIGLYVDDGVAGVGTLTFFDPKSGEY
GALGHVITETNSQVKIDIRQGKIIEARISGINTGKRGLPGEKLGTFFQTKQILGEIRKNTQYGIYGKLNRLPENPYFNEP
IPVLPASQVQEGQAKIYTVIKGGKIEEFDVSIDRVYHQSHPGAKGMIIRITDPQLKKATGGIIQGMSGSPIVQNNKLVGA
ITHVFVNDPTRGYGVFAEWMVLQTGLYDKARAVQ
>Mature_434_residues
MKRKIGLGIFFGLILIISLFYFFSINTLPSSLSIIKGNESTFNINFPFSLHIQKSGRGIGLKINGQVLGQKEFRIKENQL
QVKGDKVGSTSLNVRLFGIIPLRTINVNVLPDVKVYPGGQAIGVLLRSKGVMVVGKSFVEGKDGRKYYPAVQSGIEVGDT
ILKINGIEVYDKVKLASLIQKMAPGGKLTLEIKKKDGRIKKIPVNPVKNKQGKYMIGLYVDDGVAGVGTLTFFDPKSGEY
GALGHVITETNSQVKIDIRQGKIIEARISGINTGKRGLPGEKLGTFFQTKQILGEIRKNTQYGIYGKLNRLPENPYFNEP
IPVLPASQVQEGQAKIYTVIKGGKIEEFDVSIDRVYHQSHPGAKGMIIRITDPQLKKATGGIIQGMSGSPIVQNNKLVGA
ITHVFVNDPTRGYGVFAEWMVLQTGLYDKARAVQ

Specific function: Plays a central role in the sigma-K checkpoint which coordinates gene expression during the later stages of spore formation. The protease is activated by trans cleavage of the zymogen precursor producing SpoIVB-45 kDa. This undergoes further trimming by c

COG id: COG0750

COG function: function code M; Predicted membrane-associated Zn-dependent proteases 1

Gene ontology:

Cell location: Forespore intermembrane space [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 peptidase S55 domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR014219
- InterPro:   IPR008763 [H]

Pfam domain/function: PF00595 PDZ; PF05580 Peptidase_S55 [H]

EC number: =3.4.21.116 [H]

Molecular weight: Translated: 47545; Mature: 47545

Theoretical pI: Translated: 10.53; Mature: 10.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRKIGLGIFFGLILIISLFYFFSINTLPSSLSIIKGNESTFNINFPFSLHIQKSGRGIG
CCCEECHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEEEECCEEEEEEECCCEEE
LKINGQVLGQKEFRIKENQLQVKGDKVGSTSLNVRLFGIIPLRTINVNVLPDVKVYPGGQ
EEECCEEECCEEEEEECCEEEEECCCCCCEEEEEEEEEEEEEEEEEEEECCCCEECCCCC
AIGVLLRSKGVMVVGKSFVEGKDGRKYYPAVQSGIEVGDTILKINGIEVYDKVKLASLIQ
EEEEEEECCCEEEEECHHHCCCCCCEECHHHHCCCCCCCEEEEECCEEEEHHHHHHHHHH
KMAPGGKLTLEIKKKDGRIKKIPVNPVKNKQGKYMIGLYVDDGVAGVGTLTFFDPKSGEY
HHCCCCEEEEEEEECCCCEEEECCCCCCCCCCCEEEEEEEECCCCCEEEEEEECCCCCCC
GALGHVITETNSQVKIDIRQGKIIEARISGINTGKRGLPGEKLGTFFQTKQILGEIRKNT
CCCEEEEECCCCEEEEEEECCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCC
QYGIYGKLNRLPENPYFNEPIPVLPASQVQEGQAKIYTVIKGGKIEEFDVSIDRVYHQSH
CCCEEEECCCCCCCCCCCCCCCCCCHHHHCCCCEEEEEEEECCEEEEECCHHHHHHHCCC
PGAKGMIIRITDPQLKKATGGIIQGMSGSPIVQNNKLVGAITHVFVNDPTRGYGVFAEWM
CCCCEEEEEECCCHHHHHCCCEEECCCCCCEEECCEEEEEEEEEEECCCCCCCCHHHEEH
VLQTGLYDKARAVQ
HHHCCCCCHHHCCC
>Mature Secondary Structure
MKRKIGLGIFFGLILIISLFYFFSINTLPSSLSIIKGNESTFNINFPFSLHIQKSGRGIG
CCCEECHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEEEECCEEEEEEECCCEEE
LKINGQVLGQKEFRIKENQLQVKGDKVGSTSLNVRLFGIIPLRTINVNVLPDVKVYPGGQ
EEECCEEECCEEEEEECCEEEEECCCCCCEEEEEEEEEEEEEEEEEEEECCCCEECCCCC
AIGVLLRSKGVMVVGKSFVEGKDGRKYYPAVQSGIEVGDTILKINGIEVYDKVKLASLIQ
EEEEEEECCCEEEEECHHHCCCCCCEECHHHHCCCCCCCEEEEECCEEEEHHHHHHHHHH
KMAPGGKLTLEIKKKDGRIKKIPVNPVKNKQGKYMIGLYVDDGVAGVGTLTFFDPKSGEY
HHCCCCEEEEEEEECCCCEEEECCCCCCCCCCCEEEEEEEECCCCCEEEEEEECCCCCCC
GALGHVITETNSQVKIDIRQGKIIEARISGINTGKRGLPGEKLGTFFQTKQILGEIRKNT
CCCEEEEECCCCEEEEEEECCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCC
QYGIYGKLNRLPENPYFNEPIPVLPASQVQEGQAKIYTVIKGGKIEEFDVSIDRVYHQSH
CCCEEEECCCCCCCCCCCCCCCCCCHHHHCCCCEEEEEEEECCEEEEECCHHHHHHHCCC
PGAKGMIIRITDPQLKKATGGIIQGMSGSPIVQNNKLVGAITHVFVNDPTRGYGVFAEWM
CCCCEEEEEECCCHHHHHCCCEEECCCCCCEEECCEEEEEEEEEEECCCCCCCCHHHEEH
VLQTGLYDKARAVQ
HHHCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2106508; 8969508; 9384377; 11741860 [H]