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The map label for this gene is aroK [H]

Identifier: 220931455

GI number: 220931455

Start: 666011

End: 666526

Strand: Direct

Name: aroK [H]

Synonym: Hore_06110

Alternate gene names: 220931455

Gene position: 666011-666526 (Clockwise)

Preceding gene: 220931454

Following gene: 220931456

Centisome position: 25.83

GC content: 39.53

Gene sequence:

>516_bases
ATGAAGATATCTCTGGTTGGATTTATGGGGACAGGAAAGTCCAGTGTTGGAAAGTTGCTGGCAGAAAAATTAAATTATCC
ATTTCTGGATACCGATGACTTAATTGTAAATAAAGCCGGAATGGGGATTCCACAAATTTTTTCTAAATATGGTGAAGGGT
ATTTCCGGAAACTGGAAGAGGAAGTTTTACGCCATGTGGTGACCACCGGTGACAATTTTGTCCTGGCTACCGGTGGGGGT
ATAGTTATTTCACCATATAATAGAAAATTACTTAAAGACTATACGACACCGGTTTTATTATCAGCTTCACCGGAAGTAAT
TTATGAGCGGATCAGTGGGGATAAACGTCCTCTGCTTTTTACTGATGATCCCCTTGAGAAAATCAAGGAGCTCCTTGCAG
AAAGGGAACAATATTATAGTCAGTTTGATAATCAGGTTTATACGGGAGGCAAGGAGAAGAGAGAAGTTGTAGATGAAATT
ATTCACCTGATAGGAGTTGATAGGCTTGGACTTTAA

Upstream 100 bases:

>100_bases
CCTGGCCCAGGCTATTTTAGAGAAATTTGGTGGAGACCATATTGATGAAATCTTTGATAATTATAAACGCTTTCTGGATA
AAATGTAAGGGGTCAATAAA

Downstream 100 bases:

>100_bases
ATCAATTGAAGTCAATATACCTTCAAAGACAGTAAATTATTCTATAATTATTGGACAAGGACTGATGGAGAATGCTGGTT
CCTTAATTAAGGATGTTTAC

Product: Shikimate kinase

Products: NA

Alternate protein names: SK [H]

Number of amino acids: Translated: 171; Mature: 171

Protein sequence:

>171_residues
MKISLVGFMGTGKSSVGKLLAEKLNYPFLDTDDLIVNKAGMGIPQIFSKYGEGYFRKLEEEVLRHVVTTGDNFVLATGGG
IVISPYNRKLLKDYTTPVLLSASPEVIYERISGDKRPLLFTDDPLEKIKELLAEREQYYSQFDNQVYTGGKEKREVVDEI
IHLIGVDRLGL

Sequences:

>Translated_171_residues
MKISLVGFMGTGKSSVGKLLAEKLNYPFLDTDDLIVNKAGMGIPQIFSKYGEGYFRKLEEEVLRHVVTTGDNFVLATGGG
IVISPYNRKLLKDYTTPVLLSASPEVIYERISGDKRPLLFTDDPLEKIKELLAEREQYYSQFDNQVYTGGKEKREVVDEI
IHLIGVDRLGL
>Mature_171_residues
MKISLVGFMGTGKSSVGKLLAEKLNYPFLDTDDLIVNKAGMGIPQIFSKYGEGYFRKLEEEVLRHVVTTGDNFVLATGGG
IVISPYNRKLLKDYTTPVLLSASPEVIYERISGDKRPLLFTDDPLEKIKELLAEREQYYSQFDNQVYTGGKEKREVVDEI
IHLIGVDRLGL

Specific function: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate [H]

COG id: COG0703

COG function: function code E; Shikimate kinase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate kinase family [H]

Homologues:

Organism=Escherichia coli, GI87082255, Length=165, Percent_Identity=37.5757575757576, Blast_Score=88, Evalue=3e-19,
Organism=Escherichia coli, GI1786587, Length=161, Percent_Identity=33.5403726708075, Blast_Score=87, Evalue=6e-19,

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000623
- InterPro:   IPR023000 [H]

Pfam domain/function: PF01202 SKI [H]

EC number: =2.7.1.71 [H]

Molecular weight: Translated: 19206; Mature: 19206

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: PS01128 SHIKIMATE_KINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKISLVGFMGTGKSSVGKLLAEKLNYPFLDTDDLIVNKAGMGIPQIFSKYGEGYFRKLEE
CEEEEEEECCCCHHHHHHHHHHHCCCCCCCCCHHEEECCCCCHHHHHHHHCCHHHHHHHH
EVLRHVVTTGDNFVLATGGGIVISPYNRKLLKDYTTPVLLSASPEVIYERISGDKRPLLF
HHHHHHHHCCCCEEEEECCCEEECCCCHHHHHHCCCCEEEECCHHHHHHHHCCCCCCEEE
TDDPLEKIKELLAEREQYYSQFDNQVYTGGKEKREVVDEIIHLIGVDRLGL
CCCHHHHHHHHHHHHHHHHHHHCCCEECCCCHHHHHHHHHHHHHCCHHCCC
>Mature Secondary Structure
MKISLVGFMGTGKSSVGKLLAEKLNYPFLDTDDLIVNKAGMGIPQIFSKYGEGYFRKLEE
CEEEEEEECCCCHHHHHHHHHHHCCCCCCCCCHHEEECCCCCHHHHHHHHCCHHHHHHHH
EVLRHVVTTGDNFVLATGGGIVISPYNRKLLKDYTTPVLLSASPEVIYERISGDKRPLLF
HHHHHHHHCCCCEEEEECCCEEECCCCHHHHHHCCCCEEEECCHHHHHHHHCCCCCCEEE
TDDPLEKIKELLAEREQYYSQFDNQVYTGGKEKREVVDEIIHLIGVDRLGL
CCCHHHHHHHHHHHHHHHHHHHCCCEECCCCHHHHHHHHHHHHHCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA