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The map label for this gene is rbsK [H]

Identifier: 220931303

GI number: 220931303

Start: 491274

End: 492194

Strand: Direct

Name: rbsK [H]

Synonym: Hore_04580

Alternate gene names: 220931303

Gene position: 491274-492194 (Clockwise)

Preceding gene: 220931302

Following gene: 220931304

Centisome position: 19.06

GC content: 36.37

Gene sequence:

>921_bases
ATGACAAAGGAGATTCTTGTAATAGGTAGTTTAAACATGGATTTAATTGTCCAAACTGAAAAATACCCACGTAAAGGTGA
AACAGTACCGGGAGAAAATTTTAAACAGGTACCTGGAGGTAAGGGTGCTAATCAGGCTTTAACTGCTGGTAAGCTGGGTG
GTCAAGTAAGGTTTATTGGTTCCTGTGGGAAGGATGAGTATGGTACAACACTTTTAAATAATTTGAAAAATGGTGGAGTT
ATTGTAGACGACATTCTCAGGGTTGAAAAAAACACAGGTATTGCCATGATCACGATAGAAAAAGAGGGGTCTAACAGGAT
TATCTATGTTAAAGGGGCCAATGAATATGTTACACCTGATGTTGTAATGAAAATGGAAGATAGATTTAAAAAAGCATCAA
TTCTTTTGATTCAAATGGAGATTCCCCTGGAATCAGTTATTAAGGCTGTTGAATTGGCTAAAAAATATCAGATGAAAGTT
ATTCTTGATCCATCACCTGTACAGGGGCTCCCGGAAAAAATTTTTCCTCTTATAGATTATATACTACCAAATGAAATTGA
ATTGGATGAGTTAGTAAAAAATGGATGTCAAATTGAAGAAGAGAAAGCAAAGCACCTCCTGAAACTTGGCACAAATAATG
TAATTGTAACAAAAGGGAAGAACGGGGTTTCCCATTATTATGAAGATAAGGTTGCAACATATGAAAGCTACCATGTTAAA
GCGGTAGATACAACTGCTGCCGGTGATGCCTTTGCTGGATCATTAGCTTATGGTCTAAGCCAGGGATGGTCACTGGAAAA
AACAATTAAATTTAGTAACCTGGTTGCTGCTAACTCTGTAACAAAACTGGGAGCCCAGAGCTCACTTCCTACATATCAAG
AAGTTATGAAATTTGCGAAACATATAAAAAAAAATATATAG

Upstream 100 bases:

>100_bases
TAATTCAGGAAATTGAGGGTTCAGACCAGGATAATAACCAAAACATTCTATTAAATACGGAACTTGTAGTCAGGGGTTCT
ACAGGGGGAGTTGGTTAATA

Downstream 100 bases:

>100_bases
GTGAGGTGTCAAAACGGTGTATGAAAGTAGAACTGTAGGACAAAAAAAATTGGAACAGCTAAAACTACTTTTACCAGCAC
TAATTCCAGTCATATTATTT

Product: Ribokinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 306; Mature: 305

Protein sequence:

>306_residues
MTKEILVIGSLNMDLIVQTEKYPRKGETVPGENFKQVPGGKGANQALTAGKLGGQVRFIGSCGKDEYGTTLLNNLKNGGV
IVDDILRVEKNTGIAMITIEKEGSNRIIYVKGANEYVTPDVVMKMEDRFKKASILLIQMEIPLESVIKAVELAKKYQMKV
ILDPSPVQGLPEKIFPLIDYILPNEIELDELVKNGCQIEEEKAKHLLKLGTNNVIVTKGKNGVSHYYEDKVATYESYHVK
AVDTTAAGDAFAGSLAYGLSQGWSLEKTIKFSNLVAANSVTKLGAQSSLPTYQEVMKFAKHIKKNI

Sequences:

>Translated_306_residues
MTKEILVIGSLNMDLIVQTEKYPRKGETVPGENFKQVPGGKGANQALTAGKLGGQVRFIGSCGKDEYGTTLLNNLKNGGV
IVDDILRVEKNTGIAMITIEKEGSNRIIYVKGANEYVTPDVVMKMEDRFKKASILLIQMEIPLESVIKAVELAKKYQMKV
ILDPSPVQGLPEKIFPLIDYILPNEIELDELVKNGCQIEEEKAKHLLKLGTNNVIVTKGKNGVSHYYEDKVATYESYHVK
AVDTTAAGDAFAGSLAYGLSQGWSLEKTIKFSNLVAANSVTKLGAQSSLPTYQEVMKFAKHIKKNI
>Mature_305_residues
TKEILVIGSLNMDLIVQTEKYPRKGETVPGENFKQVPGGKGANQALTAGKLGGQVRFIGSCGKDEYGTTLLNNLKNGGVI
VDDILRVEKNTGIAMITIEKEGSNRIIYVKGANEYVTPDVVMKMEDRFKKASILLIQMEIPLESVIKAVELAKKYQMKVI
LDPSPVQGLPEKIFPLIDYILPNEIELDELVKNGCQIEEEKAKHLLKLGTNNVIVTKGKNGVSHYYEDKVATYESYHVKA
VDTTAAGDAFAGSLAYGLSQGWSLEKTIKFSNLVAANSVTKLGAQSSLPTYQEVMKFAKHIKKNI

Specific function: Ribose metabolism; first step. [C]

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=291, Percent_Identity=34.020618556701, Blast_Score=145, Evalue=6e-35,
Organism=Escherichia coli, GI1790193, Length=298, Percent_Identity=35.9060402684564, Blast_Score=178, Evalue=5e-46,
Organism=Escherichia coli, GI87082343, Length=296, Percent_Identity=26.6891891891892, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI87081971, Length=301, Percent_Identity=23.5880398671096, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1788491, Length=278, Percent_Identity=23.021582733813, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1789432, Length=276, Percent_Identity=26.8115942028986, Blast_Score=65, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17532905, Length=302, Percent_Identity=35.0993377483444, Blast_Score=162, Evalue=2e-40,
Organism=Saccharomyces cerevisiae, GI6319884, Length=334, Percent_Identity=34.1317365269461, Blast_Score=142, Evalue=7e-35,
Organism=Saccharomyces cerevisiae, GI6322565, Length=281, Percent_Identity=27.4021352313167, Blast_Score=75, Evalue=1e-14,
Organism=Drosophila melanogaster, GI20128807, Length=301, Percent_Identity=32.5581395348837, Blast_Score=140, Evalue=1e-33,
Organism=Drosophila melanogaster, GI24583886, Length=305, Percent_Identity=31.1475409836066, Blast_Score=126, Evalue=2e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR011877
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.15 [H]

Molecular weight: Translated: 33595; Mature: 33464

Theoretical pI: Translated: 8.84; Mature: 8.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKEILVIGSLNMDLIVQTEKYPRKGETVPGENFKQVPGGKGANQALTAGKLGGQVRFIG
CCCEEEEEEECCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCEEEEEE
SCGKDEYGTTLLNNLKNGGVIVDDILRVEKNTGIAMITIEKEGSNRIIYVKGANEYVTPD
CCCCCHHHHHHHHCCCCCCEEEEHHHHHHCCCCEEEEEEEECCCCEEEEEECCCCCCCHH
VVMKMEDRFKKASILLIQMEIPLESVIKAVELAKKYQMKVILDPSPVQGLPEKIFPLIDY
HHHHHHHHCCCEEEEEEEEECCHHHHHHHHHHHHHHCEEEEECCCCCCCCHHHHHHHHHH
ILPNEIELDELVKNGCQIEEEKAKHLLKLGTNNVIVTKGKNGVSHYYEDKVATYESYHVK
HCCCCCCHHHHHHCCCCCCHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHEEECCEEEE
AVDTTAAGDAFAGSLAYGLSQGWSLEKTIKFSNLVAANSVTKLGAQSSLPTYQEVMKFAK
EEECCCCCCHHHHHHHHHHCCCCCHHHEEEHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
HIKKNI
HHHHCC
>Mature Secondary Structure 
TKEILVIGSLNMDLIVQTEKYPRKGETVPGENFKQVPGGKGANQALTAGKLGGQVRFIG
CCEEEEEEECCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCEEEEEE
SCGKDEYGTTLLNNLKNGGVIVDDILRVEKNTGIAMITIEKEGSNRIIYVKGANEYVTPD
CCCCCHHHHHHHHCCCCCCEEEEHHHHHHCCCCEEEEEEEECCCCEEEEEECCCCCCCHH
VVMKMEDRFKKASILLIQMEIPLESVIKAVELAKKYQMKVILDPSPVQGLPEKIFPLIDY
HHHHHHHHCCCEEEEEEEEECCHHHHHHHHHHHHHHCEEEEECCCCCCCCHHHHHHHHHH
ILPNEIELDELVKNGCQIEEEKAKHLLKLGTNNVIVTKGKNGVSHYYEDKVATYESYHVK
HCCCCCCHHHHHHCCCCCCHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHEEECCEEEE
AVDTTAAGDAFAGSLAYGLSQGWSLEKTIKFSNLVAANSVTKLGAQSSLPTYQEVMKFAK
EEECCCCCCHHHHHHHHHHCCCCCHHHEEEHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
HIKKNI
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]