Click here to switch to the map view.

The map label for this gene is 220931301

Identifier: 220931301

GI number: 220931301

Start: 489572

End: 489940

Strand: Direct

Name: 220931301

Synonym: Hore_04560

Alternate gene names: NA

Gene position: 489572-489940 (Clockwise)

Preceding gene: 220931300

Following gene: 220931302

Centisome position: 18.99

GC content: 40.38

Gene sequence:

>369_bases
GTGAATTGCCCTTTTTGTGCCATAAGCCACAAAGATTATATTGCAGAAAATGAATATGCTTTTGCCATTTATGATAAATA
CCCCGTTAATAAAGGTCATGCCCTTATTATCCCCAAAAGACATGTAGCCAGTTATTTTGATATAACTGAAAGGGAGAGGC
AGGCTATCTTTAAACTGGTCGACAGGTGTAAAACTTTACTGGATGAGAAATTTAACCCCGATGGATACAATATCGGGATA
AATGTTGGGAAATATGCTGGCCAGACGGTCATGCACCTCCATGTCCACTTAATCCCCAGGTATAAAGGGGATATTGATGA
CCCCACTGGAGGGGTTAGAGGGGTAATACCTGAAAAGAGGGTATATTAA

Upstream 100 bases:

>100_bases
GTTAGATTGGAAAAAAGAAGTTATGAAAAATGACGTTTTTCTTGAAGATATAATCATAAACTATCTTTCAAAATTAAATT
AAAGAAAGAGGGGGTTTCAC

Downstream 100 bases:

>100_bases
AATTAACCCCCTGATCTTATCGGAGACAGGGGGTTAATTGTCTTGCGGGTCTTAATTTATATAATACTTTATTATAATAA
TCGAAGTAAAAAAATAATAA

Product: histidine triad (HIT) protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 122; Mature: 122

Protein sequence:

>122_residues
MNCPFCAISHKDYIAENEYAFAIYDKYPVNKGHALIIPKRHVASYFDITERERQAIFKLVDRCKTLLDEKFNPDGYNIGI
NVGKYAGQTVMHLHVHLIPRYKGDIDDPTGGVRGVIPEKRVY

Sequences:

>Translated_122_residues
MNCPFCAISHKDYIAENEYAFAIYDKYPVNKGHALIIPKRHVASYFDITERERQAIFKLVDRCKTLLDEKFNPDGYNIGI
NVGKYAGQTVMHLHVHLIPRYKGDIDDPTGGVRGVIPEKRVY
>Mature_122_residues
MNCPFCAISHKDYIAENEYAFAIYDKYPVNKGHALIIPKRHVASYFDITERERQAIFKLVDRCKTLLDEKFNPDGYNIGI
NVGKYAGQTVMHLHVHLIPRYKGDIDDPTGGVRGVIPEKRVY

Specific function: Unknown

COG id: COG0537

COG function: function code FGR; Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HIT domain [H]

Homologues:

Organism=Homo sapiens, GI261278358, Length=90, Percent_Identity=34.4444444444444, Blast_Score=67, Evalue=5e-12,
Organism=Homo sapiens, GI4503719, Length=90, Percent_Identity=34.4444444444444, Blast_Score=67, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17556280, Length=89, Percent_Identity=35.9550561797753, Blast_Score=69, Evalue=6e-13,
Organism=Saccharomyces cerevisiae, GI6320511, Length=88, Percent_Identity=37.5, Blast_Score=65, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6320078, Length=116, Percent_Identity=35.3448275862069, Blast_Score=61, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011146
- InterPro:   IPR011151
- InterPro:   IPR019808
- InterPro:   IPR001310 [H]

Pfam domain/function: PF01230 HIT [H]

EC number: NA

Molecular weight: Translated: 14013; Mature: 14013

Theoretical pI: Translated: 8.45; Mature: 8.45

Prosite motif: PS00892 HIT_1 ; PS51084 HIT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNCPFCAISHKDYIAENEYAFAIYDKYPVNKGHALIIPKRHVASYFDITERERQAIFKLV
CCCCEEEECCCCCCCCCCEEEEEEECCCCCCCCEEEEEHHHHHHHHCCCHHHHHHHHHHH
DRCKTLLDEKFNPDGYNIGINVGKYAGQTVMHLHVHLIPRYKGDIDDPTGGVRGVIPEKR
HHHHHHHHCCCCCCCEEEEEECCCCCCCEEEEEEEEEEECCCCCCCCCCCCEECCCCCCC
VY
CC
>Mature Secondary Structure
MNCPFCAISHKDYIAENEYAFAIYDKYPVNKGHALIIPKRHVASYFDITERERQAIFKLV
CCCCEEEECCCCCCCCCCEEEEEEECCCCCCCCEEEEEHHHHHHHHCCCHHHHHHHHHHH
DRCKTLLDEKFNPDGYNIGINVGKYAGQTVMHLHVHLIPRYKGDIDDPTGGVRGVIPEKR
HHHHHHHHCCCCCCCEEEEEECCCCCCCEEEEEEEEEEECCCCCCCCCCCCEECCCCCCC
VY
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8948633 [H]