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The map label for this gene is argB

Identifier: 220931132

GI number: 220931132

Start: 287208

End: 288080

Strand: Direct

Name: argB

Synonym: Hore_02840

Alternate gene names: 220931132

Gene position: 287208-288080 (Clockwise)

Preceding gene: 220931131

Following gene: 220931133

Centisome position: 11.14

GC content: 41.01

Gene sequence:

>873_bases
ATGGAAGAGTTAATTAATAAAGCCCAGACATTGGTGGAGGCCCTTCCCTATATAAGGAATTTTTACGGGAAAACCTTTGT
TATAAAATACGGTGGTAGTACCATGGGAGATAAGAGGTTAAAAGAAAAAATAATGGAGGATATCACCCTTTTAAAATATG
TCGGGGTTAATCCTGTTCTAATTCACGGCGGGGGGCCAGCTATAAGTGAGGCCATGGAATCCATGGATAAAGAAGCCCGG
TTTATACAGGGGCTTAGGATTACGGATAGTGAAACCATGAGCCTTGTAGAAATGGTATTGGTAGGTAAGGTGAATAAAGA
ACTGGTCTCTATCATAAACCGACTGGGTGGTGAAGCAGTTGGAATCTGTGGTAAAGATGGGGGACTCATTGAGGCTGATA
AACTTATATTTGAAGATAAATCAATTGACCTGGGACATGTCGGTAGTGTAAAAAAAATAAATCCAGAGATAGTATTGAAC
CTTATTAAAGGGGGTTATATACCAGTCATCTCCCCGGTTGGTAGTAGTAAAGAGGGAGATACTTATAATATTAACGCAGA
TACAGTGGCCGGTAAATTAGCTGTTTCACTAAAGGCAGAAAAACTGATTTTCTTAACTGATGTTGATGGGGTCTGGTCAG
ACCCCTCCAATGAAAAAACCCGGGTTTCTTCCCTGACGGTAAATGAAGTCAAAAGCTGGATTGGAGAAGGAAAAATTAAA
GGAGGAATGGTTCCCAAGGTTGAAGCCTGTATAGAGGCTGTAACCTGTGGTGTTAACCGCACCCATATTTTAAATGGTCT
AATTCCCCATGCCCTGTTACTGGAGATTTTTACAGACCGGGGTATTGGAACCATGATTTTAAAGGAGAGGTGA

Upstream 100 bases:

>100_bases
ACCTTAATCAGGGGGAGGGTTCAGCTACATTCTGGACTACGGATTTAAGCCATGATTACATTAAAATTAATGCCGATTAC
CATACATAAGGGGGATGGAG

Downstream 100 bases:

>100_bases
AAGAGTTGCTCAGAGATGAAATCATTACCTGTGATAAAAATTATTTTATGAATGTTTTTAAGGGCAGGTTTCCCCTGGTT
GTTGACCATGGGGAAGGGGT

Product: acetylglutamate kinase

Products: NA

Alternate protein names: N-acetyl-L-glutamate 5-phosphotransferase; NAG kinase; AGK

Number of amino acids: Translated: 290; Mature: 290

Protein sequence:

>290_residues
MEELINKAQTLVEALPYIRNFYGKTFVIKYGGSTMGDKRLKEKIMEDITLLKYVGVNPVLIHGGGPAISEAMESMDKEAR
FIQGLRITDSETMSLVEMVLVGKVNKELVSIINRLGGEAVGICGKDGGLIEADKLIFEDKSIDLGHVGSVKKINPEIVLN
LIKGGYIPVISPVGSSKEGDTYNINADTVAGKLAVSLKAEKLIFLTDVDGVWSDPSNEKTRVSSLTVNEVKSWIGEGKIK
GGMVPKVEACIEAVTCGVNRTHILNGLIPHALLLEIFTDRGIGTMILKER

Sequences:

>Translated_290_residues
MEELINKAQTLVEALPYIRNFYGKTFVIKYGGSTMGDKRLKEKIMEDITLLKYVGVNPVLIHGGGPAISEAMESMDKEAR
FIQGLRITDSETMSLVEMVLVGKVNKELVSIINRLGGEAVGICGKDGGLIEADKLIFEDKSIDLGHVGSVKKINPEIVLN
LIKGGYIPVISPVGSSKEGDTYNINADTVAGKLAVSLKAEKLIFLTDVDGVWSDPSNEKTRVSSLTVNEVKSWIGEGKIK
GGMVPKVEACIEAVTCGVNRTHILNGLIPHALLLEIFTDRGIGTMILKER
>Mature_290_residues
MEELINKAQTLVEALPYIRNFYGKTFVIKYGGSTMGDKRLKEKIMEDITLLKYVGVNPVLIHGGGPAISEAMESMDKEAR
FIQGLRITDSETMSLVEMVLVGKVNKELVSIINRLGGEAVGICGKDGGLIEADKLIFEDKSIDLGHVGSVKKINPEIVLN
LIKGGYIPVISPVGSSKEGDTYNINADTVAGKLAVSLKAEKLIFLTDVDGVWSDPSNEKTRVSSLTVNEVKSWIGEGKIK
GGMVPKVEACIEAVTCGVNRTHILNGLIPHALLLEIFTDRGIGTMILKER

Specific function: Arginine biosynthesis; first step. [C]

COG id: COG0548

COG function: function code E; Acetylglutamate kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetylglutamate kinase family

Homologues:

Organism=Escherichia coli, GI1789181, Length=284, Percent_Identity=29.9295774647887, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI145693208, Length=229, Percent_Identity=30.5676855895196, Blast_Score=99, Evalue=3e-22,
Organism=Saccharomyces cerevisiae, GI6320913, Length=290, Percent_Identity=27.9310344827586, Blast_Score=103, Evalue=2e-23,

Paralogues:

None

Copy number: 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): ARGB_HALOH (B8D1G8)

Other databases:

- EMBL:   CP001098
- RefSeq:   YP_002508040.1
- ProteinModelPortal:   B8D1G8
- SMR:   B8D1G8
- GeneID:   7314670
- GenomeReviews:   CP001098_GR
- KEGG:   hor:Hore_02840
- HOGENOM:   HBG497643
- OMA:   MDIVEMV
- GO:   GO:0005737
- HAMAP:   MF_00082_B
- InterPro:   IPR004662
- InterPro:   IPR001048
- InterPro:   IPR001057
- Gene3D:   G3DSA:3.40.1160.10
- PIRSF:   PIRSF000728
- PRINTS:   PR00474
- TIGRFAMs:   TIGR00761

Pfam domain/function: PF00696 AA_kinase; SSF53633 Aa_kinase

EC number: =2.7.2.8

Molecular weight: Translated: 31411; Mature: 31411

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: NA

Important sites: BINDING 86-86 BINDING 183-183

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEELINKAQTLVEALPYIRNFYGKTFVIKYGGSTMGDKRLKEKIMEDITLLKYVGVNPVL
CHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCEEE
IHGGGPAISEAMESMDKEARFIQGLRITDSETMSLVEMVLVGKVNKELVSIINRLGGEAV
EECCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCEE
GICGKDGGLIEADKLIFEDKSIDLGHVGSVKKINPEIVLNLIKGGYIPVISPVGSSKEGD
EEECCCCCEEEHHHEEEECCCCCCCCCCCCCCCCHHHHHHHHCCCCEEEECCCCCCCCCC
TYNINADTVAGKLAVSLKAEKLIFLTDVDGVWSDPSNEKTRVSSLTVNEVKSWIGEGKIK
EEECCHHHHHHHEEEEEEECEEEEEEECCCCCCCCCCCCHHHHHEEHHHHHHHHCCCCCC
GGMVPKVEACIEAVTCGVNRTHILNGLIPHALLLEIFTDRGIGTMILKER
CCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECC
>Mature Secondary Structure
MEELINKAQTLVEALPYIRNFYGKTFVIKYGGSTMGDKRLKEKIMEDITLLKYVGVNPVL
CHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCEEE
IHGGGPAISEAMESMDKEARFIQGLRITDSETMSLVEMVLVGKVNKELVSIINRLGGEAV
EECCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCEE
GICGKDGGLIEADKLIFEDKSIDLGHVGSVKKINPEIVLNLIKGGYIPVISPVGSSKEGD
EEECCCCCEEEHHHEEEECCCCCCCCCCCCCCCCHHHHHHHHCCCCEEEECCCCCCCCCC
TYNINADTVAGKLAVSLKAEKLIFLTDVDGVWSDPSNEKTRVSSLTVNEVKSWIGEGKIK
EEECCHHHHHHHEEEEEEECEEEEEEECCCCCCCCCCCCHHHHHEEHHHHHHHHCCCCCC
GGMVPKVEACIEAVTCGVNRTHILNGLIPHALLLEIFTDRGIGTMILKER
CCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA