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The map label for this gene is dctS [H]

Identifier: 220931012

GI number: 220931012

Start: 169496

End: 170473

Strand: Direct

Name: dctS [H]

Synonym: Hore_01630

Alternate gene names: 220931012

Gene position: 169496-170473 (Clockwise)

Preceding gene: 220931011

Following gene: 220931013

Centisome position: 6.57

GC content: 36.81

Gene sequence:

>978_bases
ATGCTACTTATTGTTTGGCTAATAAAAAGGTATAATATTAATTTCAGGGAAGGTTTTTTTCATTTATCTCCAGATGAAAT
TGAATTAATAGGTAAAGAAGAGGTCAAACGGGAAAAGAAAATAACCTCAACCCTGCTGTTGGCTCTCTTTTTTATTATAA
TACAGGGAATGTTTATCAATATGTACAACTGGTCCCGGAGATTGAGCCATTTATTTGATATTGAATTATCTTTTTTTACG
TCATCTGAATTCATCAATATAATTGTAATCATTCTGAGTATATTTTTAATATGGTTGGTTCAGCATATGGTAGGTATGCT
TAAAATCCAGAGGAATGAAATCATAGAGAAGATAAAAAGGAAATCAAAGGAGAGACTCGACTGGGAGCTAAGAATGCAGT
ACCATGATTTTAACCATCACCTGGGAATGTTGAGTATGATGTTACAGATGGATCAGGTCAGCGCTGCTAAAAAATACCTG
AAGGGGATGGTAAAAGAACTGGGAAAAATTAAAAAGCTGGAAAGCAGTGGGAATCCTGCCTTGAATGCCCTGATTCAGAG
TAAAATAGCCCGGGGGCAGAAGATGGGGGTTAAAATTGATGTGGAATTAGTTAACCCTCTTAAAGGAGAGTATATTCCCG
ACTGGGAACTGGTCAGGGTATGTGGAAACCTTCTCGATAATTCCATTGAAGCTTTACAACAGCTTCCGCGGGATACAGAA
AAGAGAGTTAAAATAGAAATAGATGGGGAAAAAGATATTCTAACTATCTCTGTAACTACTTTCGGGGTCGTAATTCCTGA
TGAGATTAAAGAACATATCTTTGAAAGGGGTTTTACCAGCAAAAAGGAAAAAGGCCATGGTCTCGGCCTGGCTATCTGTA
AGGAGATTACAGATAAATATCAGGGGCAGATCTCAATTAGAAAAGATGAAGAACGGGAGACAACGACATTTACCGTTAAA
TTACCAAAGAATACATAA

Upstream 100 bases:

>100_bases
TATTAATTCCTTTACTGGGATTTATATTTAATGTTGAGTTAAATATGGCTATGAATACGCCTTTGATTAGAATAAAATTT
TTATAGTTCAATGTGTTATA

Downstream 100 bases:

>100_bases
AAAATCAAATTTATTCTATAAAGTGATAGCTTGACCTCATACATATTCTGATATAATAAGGGTAGAGTAGATATTTCATA
ATTTTATGTGTGAAAATAAT

Product: signal transduction histidine kinase regulating citrate/malate metabolism

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 325; Mature: 325

Protein sequence:

>325_residues
MLLIVWLIKRYNINFREGFFHLSPDEIELIGKEEVKREKKITSTLLLALFFIIIQGMFINMYNWSRRLSHLFDIELSFFT
SSEFINIIVIILSIFLIWLVQHMVGMLKIQRNEIIEKIKRKSKERLDWELRMQYHDFNHHLGMLSMMLQMDQVSAAKKYL
KGMVKELGKIKKLESSGNPALNALIQSKIARGQKMGVKIDVELVNPLKGEYIPDWELVRVCGNLLDNSIEALQQLPRDTE
KRVKIEIDGEKDILTISVTTFGVVIPDEIKEHIFERGFTSKKEKGHGLGLAICKEITDKYQGQISIRKDEERETTTFTVK
LPKNT

Sequences:

>Translated_325_residues
MLLIVWLIKRYNINFREGFFHLSPDEIELIGKEEVKREKKITSTLLLALFFIIIQGMFINMYNWSRRLSHLFDIELSFFT
SSEFINIIVIILSIFLIWLVQHMVGMLKIQRNEIIEKIKRKSKERLDWELRMQYHDFNHHLGMLSMMLQMDQVSAAKKYL
KGMVKELGKIKKLESSGNPALNALIQSKIARGQKMGVKIDVELVNPLKGEYIPDWELVRVCGNLLDNSIEALQQLPRDTE
KRVKIEIDGEKDILTISVTTFGVVIPDEIKEHIFERGFTSKKEKGHGLGLAICKEITDKYQGQISIRKDEERETTTFTVK
LPKNT
>Mature_325_residues
MLLIVWLIKRYNINFREGFFHLSPDEIELIGKEEVKREKKITSTLLLALFFIIIQGMFINMYNWSRRLSHLFDIELSFFT
SSEFINIIVIILSIFLIWLVQHMVGMLKIQRNEIIEKIKRKSKERLDWELRMQYHDFNHHLGMLSMMLQMDQVSAAKKYL
KGMVKELGKIKKLESSGNPALNALIQSKIARGQKMGVKIDVELVNPLKGEYIPDWELVRVCGNLLDNSIEALQQLPRDTE
KRVKIEIDGEKDILTISVTTFGVVIPDEIKEHIFERGFTSKKEKGHGLGLAICKEITDKYQGQISIRKDEERETTTFTVK
LPKNT

Specific function: Member of the two-component regulatory system dctS/dctR. Probably activates dctR by phosphorylation. Essential for expression of dctP [H]

COG id: COG3290

COG function: function code T; Signal transduction histidine kinase regulating citrate/malate metabolism

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR016120
- InterPro:   IPR005467
- InterPro:   IPR016121 [H]

Pfam domain/function: PF02518 HATPase_c; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 37867; Mature: 37867

Theoretical pI: Translated: 9.58; Mature: 9.58

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLIVWLIKRYNINFREGFFHLSPDEIELIGKEEVKREKKITSTLLLALFFIIIQGMFIN
CEEEEEEHHHHCCCHHCCEEECCCHHHEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MYNWSRRLSHLFDIELSFFTSSEFINIIVIILSIFLIWLVQHMVGMLKIQRNEIIEKIKR
HHHHHHHHHHHHHHEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KSKERLDWELRMQYHDFNHHLGMLSMMLQMDQVSAAKKYLKGMVKELGKIKKLESSGNPA
HHHHCCCHHEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
LNALIQSKIARGQKMGVKIDVELVNPLKGEYIPDWELVRVCGNLLDNSIEALQQLPRDTE
HHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCC
KRVKIEIDGEKDILTISVTTFGVVIPDEIKEHIFERGFTSKKEKGHGLGLAICKEITDKY
CEEEEEECCCCCEEEEEEEEEEEEECHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHH
QGQISIRKDEERETTTFTVKLPKNT
CCEEEEECCCCCCEEEEEEEECCCC
>Mature Secondary Structure
MLLIVWLIKRYNINFREGFFHLSPDEIELIGKEEVKREKKITSTLLLALFFIIIQGMFIN
CEEEEEEHHHHCCCHHCCEEECCCHHHEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MYNWSRRLSHLFDIELSFFTSSEFINIIVIILSIFLIWLVQHMVGMLKIQRNEIIEKIKR
HHHHHHHHHHHHHHEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KSKERLDWELRMQYHDFNHHLGMLSMMLQMDQVSAAKKYLKGMVKELGKIKKLESSGNPA
HHHHCCCHHEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
LNALIQSKIARGQKMGVKIDVELVNPLKGEYIPDWELVRVCGNLLDNSIEALQQLPRDTE
HHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCC
KRVKIEIDGEKDILTISVTTFGVVIPDEIKEHIFERGFTSKKEKGHGLGLAICKEITDKY
CEEEEEECCCCCEEEEEEEEEEEEECHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHH
QGQISIRKDEERETTTFTVKLPKNT
CCEEEEECCCCCCEEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]