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The map label for this gene is gufA [H]

Identifier: 220930867

GI number: 220930867

Start: 18626

End: 19411

Strand: Direct

Name: gufA [H]

Synonym: Hore_00170

Alternate gene names: 220930867

Gene position: 18626-19411 (Clockwise)

Preceding gene: 220930866

Following gene: 220930868

Centisome position: 0.72

GC content: 41.48

Gene sequence:

>786_bases
ATGATTGAAGAGTATTTAAGTCATTTTAATATGGTTTATTTAGGTTTACTGGCAAGTCTGGTAGCCGGCCTGGCTACAGG
TATTGGAGGATTGCCGGTTTTATTTACTAAAAATATAAGTCAAAAAATATTAAACTCAATGTTGGGGTTTGCGGCTGGAA
TAATGCTGGCGGCAACTTCCTTTAGTTTAATAATTCCAGCTATAAGTTATGGTGGTGGCGGGGTTAAAGGGGCTTCAATA
GCTTTTTTTGGAATAATCCTGGGAGGTTTTTTTCTGGACTCAATCGACCGTTATTTTCCTAATACTAATTTGCTATCAGG
TTCAATTGACGAAAACCCTAACCTCAAAAGGATCTGGCTTTTTGCAACAGCAATTACCCTGCACAATTTTCCTGAAGGAT
TAGCAGTCGGGGTTGGTTTCGGTAATGGAGATGTTTTAAATGGTATGAGTCTCGCCATAGCTATTGGGTTACAGAATATC
CCGGAAGGACTGGCTGTAGCCTTACCCTTTGTCCGGGAGGGTGTTAATAAGTGGAAGGCAGTAGGTATAGCCCTGGCTAC
GGGTCTTGTGGAGCCAGTTGGAGGAATACTTGGAGCCGGTTTAGTTCAGATATCACGACCCCTGTTACCGGTATTTCTTG
CCTTTGCTGCTGGAGCCATGTTATTTGTTATCAGCTATGAAATAATACCGGAAAGCCAGAAAGATGCCATGTTCTCTAAA
CTATCTTCCCATGCCCTTCTACTGGGATTTGTTATTATGATGTTTTTAGACAATGTTCTCGGTTAA

Upstream 100 bases:

>100_bases
AGGAGTAATTTTAAATTATACCCTGCCTCTGTTCACTGGATAAGCACCTGATGAATAGTATATGGGTGATGATTTCCGGT
GAAAAGGGGGTAGGGTTATT

Downstream 100 bases:

>100_bases
TCTCAAAAAAATCCTTGACAAGAGGGACTAATGATGTTAAGATAATAATCGCGCCTCAAAAAAAGAGGCCATAACAACAG
AGTCAAGGGTTCAGGCTGAT

Product: zinc/iron permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 261; Mature: 261

Protein sequence:

>261_residues
MIEEYLSHFNMVYLGLLASLVAGLATGIGGLPVLFTKNISQKILNSMLGFAAGIMLAATSFSLIIPAISYGGGGVKGASI
AFFGIILGGFFLDSIDRYFPNTNLLSGSIDENPNLKRIWLFATAITLHNFPEGLAVGVGFGNGDVLNGMSLAIAIGLQNI
PEGLAVALPFVREGVNKWKAVGIALATGLVEPVGGILGAGLVQISRPLLPVFLAFAAGAMLFVISYEIIPESQKDAMFSK
LSSHALLLGFVIMMFLDNVLG

Sequences:

>Translated_261_residues
MIEEYLSHFNMVYLGLLASLVAGLATGIGGLPVLFTKNISQKILNSMLGFAAGIMLAATSFSLIIPAISYGGGGVKGASI
AFFGIILGGFFLDSIDRYFPNTNLLSGSIDENPNLKRIWLFATAITLHNFPEGLAVGVGFGNGDVLNGMSLAIAIGLQNI
PEGLAVALPFVREGVNKWKAVGIALATGLVEPVGGILGAGLVQISRPLLPVFLAFAAGAMLFVISYEIIPESQKDAMFSK
LSSHALLLGFVIMMFLDNVLG
>Mature_261_residues
MIEEYLSHFNMVYLGLLASLVAGLATGIGGLPVLFTKNISQKILNSMLGFAAGIMLAATSFSLIIPAISYGGGGVKGASI
AFFGIILGGFFLDSIDRYFPNTNLLSGSIDENPNLKRIWLFATAITLHNFPEGLAVGVGFGNGDVLNGMSLAIAIGLQNI
PEGLAVALPFVREGVNKWKAVGIALATGLVEPVGGILGAGLVQISRPLLPVFLAFAAGAMLFVISYEIIPESQKDAMFSK
LSSHALLLGFVIMMFLDNVLG

Specific function: Mediates Zinc Uptake. May Also Transport Other Divalent Cations Such As Copper And Cadmium Ions. [C]

COG id: COG0428

COG function: function code P; Predicted divalent heavy-metal cations transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI229577418, Length=154, Percent_Identity=49.3506493506493, Blast_Score=130, Evalue=1e-30,
Organism=Homo sapiens, GI229577422, Length=154, Percent_Identity=49.3506493506493, Blast_Score=130, Evalue=2e-30,
Organism=Escherichia coli, GI1789419, Length=188, Percent_Identity=36.1702127659575, Blast_Score=78, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17507805, Length=317, Percent_Identity=34.0694006309148, Blast_Score=142, Evalue=2e-34,
Organism=Drosophila melanogaster, GI24652846, Length=157, Percent_Identity=42.0382165605096, Blast_Score=110, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003689 [H]

Pfam domain/function: PF02535 Zip [H]

EC number: NA

Molecular weight: Translated: 27323; Mature: 27323

Theoretical pI: Translated: 5.64; Mature: 5.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEEYLSHFNMVYLGLLASLVAGLATGIGGLPVLFTKNISQKILNSMLGFAAGIMLAATS
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FSLIIPAISYGGGGVKGASIAFFGIILGGFFLDSIDRYFPNTNLLSGSIDENPNLKRIWL
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEHH
FATAITLHNFPEGLAVGVGFGNGDVLNGMSLAIAIGLQNIPEGLAVALPFVREGVNKWKA
HHHHHHHHCCCCCEEEEEECCCCCHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
VGIALATGLVEPVGGILGAGLVQISRPLLPVFLAFAAGAMLFVISYEIIPESQKDAMFSK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
LSSHALLLGFVIMMFLDNVLG
HHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIEEYLSHFNMVYLGLLASLVAGLATGIGGLPVLFTKNISQKILNSMLGFAAGIMLAATS
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FSLIIPAISYGGGGVKGASIAFFGIILGGFFLDSIDRYFPNTNLLSGSIDENPNLKRIWL
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEHH
FATAITLHNFPEGLAVGVGFGNGDVLNGMSLAIAIGLQNIPEGLAVALPFVREGVNKWKA
HHHHHHHHCCCCCEEEEEECCCCCHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
VGIALATGLVEPVGGILGAGLVQISRPLLPVFLAFAAGAMLFVISYEIIPESQKDAMFSK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
LSSHALLLGFVIMMFLDNVLG
HHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7934835 [H]