Click here to switch to the map view.

The map label for this gene is ppa [H]

Identifier: 220919328

GI number: 220919328

Start: 4731603

End: 4732151

Strand: Direct

Name: ppa [H]

Synonym: A2cp1_4249

Alternate gene names: 220919328

Gene position: 4731603-4732151 (Clockwise)

Preceding gene: 220919326

Following gene: 220919329

Centisome position: 94.08

GC content: 74.86

Gene sequence:

>549_bases
ATGACCGACCTCGCCCGGCTCCCTCCGCGCGACGAGCGCGGCGCGCTGCGCGTGGTGGTGGAGTCGCCGCGCGGTGCAAG
CCTGAAGCTGAAGTACGACGCGGAGCTGGGCGTGGTGACGGTGTCGCGCCCGCTGCCGCTCGGGCTCGCCTACCCGTACG
ACTGGGGGTTCATCCCGGGCACGCGCGCGCCGGACGGCGACCCGGTGGACGCCCTCGTCTACTGGGACGCGGTGAGCTTC
CCCGGGGTGGTGGTGCCGTGCCGCGCCGTGGGCGTGGTGCGCCTGGAGCAGGACTCGAGGTCGAACGGCCGGGTGCGCAA
CGACCGCATCCTGGCCGTCCCGGTGAAGCACCCGCGGGGCGACGACCTCCGCTCGCCGGACGACCTGCCCGCGCGGGTCC
GCGACGAGATCGCGCAGTTCTTCCTCTCCGCGATCTTCTTCGAGCCGAAGAACCCGGCGCTGCTGGGCTGGGGCGGGCCG
GAGGAGGCCGAGCGCCTGGTGGACGGCTGCACGCGCGCGCTCGCGGCCGTGATCCGGCGCCGCTCCTGA

Upstream 100 bases:

>100_bases
CCGGCGGCGCACGCCCGCCCGCCCGCCGAGCGGGGACACCGGTCGGGTTCCTACCGGTCATGCAATTGCCCGGCGGGGCG
TGCCCCGGCATGTCGAGGAG

Downstream 100 bases:

>100_bases
TCCAGCGCAAGCCGCCGCCGTCCCCCTGGCCGATCGCGCGCCGGCGGGGTGGGCCGGAGGCGGGCCCCTGCGGTAATCTC
GCCGTTCACCCGGCGGGCGC

Product: Inorganic pyrophosphatase

Products: NA

Alternate protein names: Pyrophosphate phospho-hydrolase; PPase [H]

Number of amino acids: Translated: 182; Mature: 181

Protein sequence:

>182_residues
MTDLARLPPRDERGALRVVVESPRGASLKLKYDAELGVVTVSRPLPLGLAYPYDWGFIPGTRAPDGDPVDALVYWDAVSF
PGVVVPCRAVGVVRLEQDSRSNGRVRNDRILAVPVKHPRGDDLRSPDDLPARVRDEIAQFFLSAIFFEPKNPALLGWGGP
EEAERLVDGCTRALAAVIRRRS

Sequences:

>Translated_182_residues
MTDLARLPPRDERGALRVVVESPRGASLKLKYDAELGVVTVSRPLPLGLAYPYDWGFIPGTRAPDGDPVDALVYWDAVSF
PGVVVPCRAVGVVRLEQDSRSNGRVRNDRILAVPVKHPRGDDLRSPDDLPARVRDEIAQFFLSAIFFEPKNPALLGWGGP
EEAERLVDGCTRALAAVIRRRS
>Mature_181_residues
TDLARLPPRDERGALRVVVESPRGASLKLKYDAELGVVTVSRPLPLGLAYPYDWGFIPGTRAPDGDPVDALVYWDAVSFP
GVVVPCRAVGVVRLEQDSRSNGRVRNDRILAVPVKHPRGDDLRSPDDLPARVRDEIAQFFLSAIFFEPKNPALLGWGGPE
EAERLVDGCTRALAAVIRRRS

Specific function: Hydrolyzes PPi generated in anabolic reactions [H]

COG id: COG0221

COG function: function code C; Inorganic pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PPase family [H]

Homologues:

Organism=Escherichia coli, GI1790673, Length=153, Percent_Identity=32.0261437908497, Blast_Score=69, Evalue=2e-13,

Paralogues:

None

Copy number: 5480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008162 [H]

Pfam domain/function: PF00719 Pyrophosphatase [H]

EC number: =3.6.1.1 [H]

Molecular weight: Translated: 20007; Mature: 19876

Theoretical pI: Translated: 8.20; Mature: 8.20

Prosite motif: PS00387 PPASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDLARLPPRDERGALRVVVESPRGASLKLKYDAELGVVTVSRPLPLGLAYPYDWGFIPG
CCCCCCCCCCCCCCEEEEEEECCCCCEEEEEECCCEEEEEECCCCCCCEECCCCCCCCCC
TRAPDGDPVDALVYWDAVSFPGVVVPCRAVGVVRLEQDSRSNGRVRNDRILAVPVKHPRG
CCCCCCCCCEEEEEEECCCCCCEEECCCEEEEEEECCCCCCCCCCCCCEEEEEECCCCCC
DDLRSPDDLPARVRDEIAQFFLSAIFFEPKNPALLGWGGPEEAERLVDGCTRALAAVIRR
CCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHC
RS
CC
>Mature Secondary Structure 
TDLARLPPRDERGALRVVVESPRGASLKLKYDAELGVVTVSRPLPLGLAYPYDWGFIPG
CCCCCCCCCCCCCEEEEEEECCCCCEEEEEECCCEEEEEECCCCCCCEECCCCCCCCCC
TRAPDGDPVDALVYWDAVSFPGVVVPCRAVGVVRLEQDSRSNGRVRNDRILAVPVKHPRG
CCCCCCCCCEEEEEEECCCCCCEEECCCEEEEEEECCCCCCCCCCCCCEEEEEECCCCCC
DDLRSPDDLPARVRDEIAQFFLSAIFFEPKNPALLGWGGPEEAERLVDGCTRALAAVIRR
CCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHC
RS
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]