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The map label for this gene is murG

Identifier: 220918996

GI number: 220918996

Start: 4351181

End: 4352332

Strand: Direct

Name: murG

Synonym: A2cp1_3911

Alternate gene names: 220918996

Gene position: 4351181-4352332 (Clockwise)

Preceding gene: 220918995

Following gene: 220918997

Centisome position: 86.52

GC content: 74.05

Gene sequence:

>1152_bases
ATGAGGATGATGGTGGCGGGCGGCGGCACCGGCGGCCACGTGTTCCCCGGCATCGCGCTGGCGGAGGAGGTGGTCACGCG
CCACCCCGCCAACGACGTGGTCTTCGTGGGCACCGCCCGCGGCCTGGAGGCCTCGGTGGTCCCGGCCGCCGGCTTCCCCA
TCGAGCTCATCGAGGTGAAGGGGCTGAAGGGGAAGGGCATCGCGGGCGCGCTGCTCAACCTGCTGCTGCTGCCCCGCGCG
TTCCTCCAGTCCTGGCGCATCCTGCGGCGCTGGCGGCCGGACGTGGTGGTGGGCGTGGGCGGCTACGCCAGCGGCCCGGT
GGTGCTCACCGCCTGGGCCATGCGCATCCCCACCGCGGTGCAGGAGCAGAACGCGATCGCCGGCCTCACCAACCGGCTCC
TCGGGCGCGTCGTGAAGGCGGCGTTCACCGCGTTCCCCGAGGCGGCCCGGCACTTCGCGGCCCGCAAGGTCTACCAGCTC
GGCAACCCCATCCGCCGGCGGCTGATGGAGAACTACATGCGGCCCGAGTCGGCGCACGGCCAGCCGCGGCTGCTCGTGTT
CGGTGGCTCGCAGGGCGCGCACGCGCTCAACATGCGCGTCATCGAGGCGCTGCCGCACCTCGCCGACCTGCGCGAGCGGA
TCCAGATCACGCACCAGACCGGCGCGCGCGACCGCGAGTACGTCGAGAAGGGCTACCGCGCCTGCGGGTTCACCCCGGAC
GTGCGCGAGTTCATCGACGACATGAGCGCGGCGTACGCGGGCTGCGACCTGGTGGTGTGCCGGGCCGGCGCGACCACGCT
CGCCGAGCTGACCGTCTGCAAGAAGCCGTCGATCCTGGTCCCCTTCCCCGCCGCCGCCGACAACCACCAGGTGAAGAACG
CGCGCAGCCTGGTGGACGCAGGGGCCGCGGTGATGATCGAGGAGCGCGACCTCACCGGCGAGGTGCTGGCGCGCGAGATC
CGCGAGATCCTGGACGCGCCGGAGCGCCGCGAGCGGATGGCGCGGGCCGCGGGCCGGCTGGGCAGCCCGCAGGCCGCCAA
GGAGATCGCGGACGTGTGCATGGAGCTGGTCCGCCGCCGCTGGGGCTCGCCCTTCGGCCAGGCGCGCGAGCCCGGGCAGA
AGCCCGCGCGCCCGCCGGATCCCGCGTCGTAG

Upstream 100 bases:

>100_bases
AGCGCGGCGGCTTCCTGACCCGGGCGCCCGCGGCGGTGCGGGTGGGCGCGCCCATCGGCGGCGCGCCGCGGCTGTCCGCG
GCCCGCGCGGAGGACGCGTC

Downstream 100 bases:

>100_bases
CGCCCGAGGAGCGTCCCGAGACATGAGCCTCTTCCGTTCCAGGCAGGCCAAGATCCACTTCGTGGGCGTGGGCGGCATCG
GCATGAGCGGCATCGCCGAG

Product: undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase

Number of amino acids: Translated: 383; Mature: 383

Protein sequence:

>383_residues
MRMMVAGGGTGGHVFPGIALAEEVVTRHPANDVVFVGTARGLEASVVPAAGFPIELIEVKGLKGKGIAGALLNLLLLPRA
FLQSWRILRRWRPDVVVGVGGYASGPVVLTAWAMRIPTAVQEQNAIAGLTNRLLGRVVKAAFTAFPEAARHFAARKVYQL
GNPIRRRLMENYMRPESAHGQPRLLVFGGSQGAHALNMRVIEALPHLADLRERIQITHQTGARDREYVEKGYRACGFTPD
VREFIDDMSAAYAGCDLVVCRAGATTLAELTVCKKPSILVPFPAAADNHQVKNARSLVDAGAAVMIEERDLTGEVLAREI
REILDAPERRERMARAAGRLGSPQAAKEIADVCMELVRRRWGSPFGQAREPGQKPARPPDPAS

Sequences:

>Translated_383_residues
MRMMVAGGGTGGHVFPGIALAEEVVTRHPANDVVFVGTARGLEASVVPAAGFPIELIEVKGLKGKGIAGALLNLLLLPRA
FLQSWRILRRWRPDVVVGVGGYASGPVVLTAWAMRIPTAVQEQNAIAGLTNRLLGRVVKAAFTAFPEAARHFAARKVYQL
GNPIRRRLMENYMRPESAHGQPRLLVFGGSQGAHALNMRVIEALPHLADLRERIQITHQTGARDREYVEKGYRACGFTPD
VREFIDDMSAAYAGCDLVVCRAGATTLAELTVCKKPSILVPFPAAADNHQVKNARSLVDAGAAVMIEERDLTGEVLAREI
REILDAPERRERMARAAGRLGSPQAAKEIADVCMELVRRRWGSPFGQAREPGQKPARPPDPAS
>Mature_383_residues
MRMMVAGGGTGGHVFPGIALAEEVVTRHPANDVVFVGTARGLEASVVPAAGFPIELIEVKGLKGKGIAGALLNLLLLPRA
FLQSWRILRRWRPDVVVGVGGYASGPVVLTAWAMRIPTAVQEQNAIAGLTNRLLGRVVKAAFTAFPEAARHFAARKVYQL
GNPIRRRLMENYMRPESAHGQPRLLVFGGSQGAHALNMRVIEALPHLADLRERIQITHQTGARDREYVEKGYRACGFTPD
VREFIDDMSAAYAGCDLVVCRAGATTLAELTVCKKPSILVPFPAAADNHQVKNARSLVDAGAAVMIEERDLTGEVLAREI
REILDAPERRERMARAAGRLGSPQAAKEIADVCMELVRRRWGSPFGQAREPGQKPARPPDPAS

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily

Homologues:

Organism=Escherichia coli, GI1786278, Length=366, Percent_Identity=39.0710382513661, Blast_Score=219, Evalue=2e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURG_ANAD2 (B8J8E8)

Other databases:

- EMBL:   CP001359
- RefSeq:   YP_002494300.1
- ProteinModelPortal:   B8J8E8
- SMR:   B8J8E8
- GeneID:   7297251
- GenomeReviews:   CP001359_GR
- KEGG:   acp:A2cp1_3911
- HOGENOM:   HBG617076
- ProtClustDB:   PRK00726
- HAMAP:   MF_00033
- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235
- TIGRFAMs:   TIGR01133

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28

EC number: =2.4.1.227

Molecular weight: Translated: 41532; Mature: 41532

Theoretical pI: Translated: 10.24; Mature: 10.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRMMVAGGGTGGHVFPGIALAEEVVTRHPANDVVFVGTARGLEASVVPAAGFPIELIEVK
CEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCEEEEEEC
GLKGKGIAGALLNLLLLPRAFLQSWRILRRWRPDVVVGVGGYASGPVVLTAWAMRIPTAV
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHCCHHH
QEQNAIAGLTNRLLGRVVKAAFTAFPEAARHFAARKVYQLGNPIRRRLMENYMRPESAHG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCC
QPRLLVFGGSQGAHALNMRVIEALPHLADLRERIQITHQTGARDREYVEKGYRACGFTPD
CCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHH
VREFIDDMSAAYAGCDLVVCRAGATTLAELTVCKKPSILVPFPAAADNHQVKNARSLVDA
HHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHHC
GAAVMIEERDLTGEVLAREIREILDAPERRERMARAAGRLGSPQAAKEIADVCMELVRRR
CCEEEEECCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
WGSPFGQAREPGQKPARPPDPAS
CCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRMMVAGGGTGGHVFPGIALAEEVVTRHPANDVVFVGTARGLEASVVPAAGFPIELIEVK
CEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCEEEEEEC
GLKGKGIAGALLNLLLLPRAFLQSWRILRRWRPDVVVGVGGYASGPVVLTAWAMRIPTAV
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHCCHHH
QEQNAIAGLTNRLLGRVVKAAFTAFPEAARHFAARKVYQLGNPIRRRLMENYMRPESAHG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCC
QPRLLVFGGSQGAHALNMRVIEALPHLADLRERIQITHQTGARDREYVEKGYRACGFTPD
CCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHH
VREFIDDMSAAYAGCDLVVCRAGATTLAELTVCKKPSILVPFPAAADNHQVKNARSLVDA
HHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHHC
GAAVMIEERDLTGEVLAREIREILDAPERRERMARAAGRLGSPQAAKEIADVCMELVRRR
CCEEEEECCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
WGSPFGQAREPGQKPARPPDPAS
CCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA