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The map label for this gene is nhaA2 [H]

Identifier: 220918868

GI number: 220918868

Start: 4201396

End: 4202331

Strand: Direct

Name: nhaA2 [H]

Synonym: A2cp1_3782

Alternate gene names: 220918868

Gene position: 4201396-4202331 (Clockwise)

Preceding gene: 220918866

Following gene: 220918869

Centisome position: 83.54

GC content: 77.03

Gene sequence:

>936_bases
ATGACCGTCTCCCGCTCGATCCTCCTCGCCGCGCTCGCGGCCCTCGGCCTCGCCGGCCTGCCCGCCTGCAAGACCGCCGC
GCCCGCACCGGGCGCCCCCGCCGCCGCCGCCCCCGCCGGCGCCGCCCCCGCCGCCACCGCCGACCCGCTCGCCGGCGTGG
ACCTCGACGACCTCACCCCGGAGCAGCGCGCCATCGTGCGCGACTGGGCCTCGCGGGCGTTCTGCTACTGCGGCTGCCCG
CACACGGTCACGAGCTGCCTGCGCACCCACCAGCCGTGCAAGCACGCGGCGCGCATGGCTCGCCTCGCGGCGCGCCTGGT
CGCGGCCGGCGCCGGCCCCTCGGCCCTGCCGGGCCTGGTGGACGACTACTACGCCTCGTTCGACCGCCGCATGGCGCTCG
CCACCGACGGCTTCGGCCCGCCGCTCGGCGACCCGGCGGCGCCCGTCACGCTGCTGGAGTTCTCCGACTTCACCTGCCCG
TTCTGCCGGGGTCTCCGCCCGGCGCTGGAGCGCTTCGTGGAGGAGCACCCCGGCCGCGTGAAGCTCGTCTTCAAGCCGTT
CCCCATCGAGGCGCACCCCGGCGCGCTGGAGGCGGCGCAGGCCGGCGAATGGGCGCGCGACCAGGGCATCTTCTGGCCGC
TGCACGACGCGCTGTTCGAGGCGGCGGCGCCGCTCGACGTGGACGCGATCGCGGCGGCCGCGCGCGAGGCGGGCGGCGAC
GCGGGCGACCTCCGCGACGCGCTCGCCAGCCGGAAGTACCTGGACAAGATCCGCGCCTCGCAGGCGGAGGCGCGCGCCGC
CGGGCTTCGCGGCACGCCCACGCTGTTCCTGAACGGCCGCTACCTGGCCCTGCCCGACTTCTCGCCCGCGATGCTGCTGC
ACGCGCTGGAGGACGAGGAGGAGTGGCAGCAGCACCAGGGCTGGGAGAAGGACTGA

Upstream 100 bases:

>100_bases
AGCAGACCATGGGGGCCGTGCCACGTTCAAAGCGTGCGGCGCCCACCCCGCGGGCGGGTCGTACTAGAATCCCGCGACCG
CGCTCCCCGGGGCTCCCTCC

Downstream 100 bases:

>100_bases
CCCTCCTCGTCGACATCGACGCCCACGGGCGGCTGGTCCCCCAGACCGACGAGGTCCGGCGCGCGCTCGCCGACCGCGCC
GGGCGCTTCGTGCTCCTGCC

Product: DSBA oxidoreductase

Products: NA

Alternate protein names: Sodium/proton antiporter nhaA 2 [H]

Number of amino acids: Translated: 311; Mature: 310

Protein sequence:

>311_residues
MTVSRSILLAALAALGLAGLPACKTAAPAPGAPAAAAPAGAAPAATADPLAGVDLDDLTPEQRAIVRDWASRAFCYCGCP
HTVTSCLRTHQPCKHAARMARLAARLVAAGAGPSALPGLVDDYYASFDRRMALATDGFGPPLGDPAAPVTLLEFSDFTCP
FCRGLRPALERFVEEHPGRVKLVFKPFPIEAHPGALEAAQAGEWARDQGIFWPLHDALFEAAAPLDVDAIAAAAREAGGD
AGDLRDALASRKYLDKIRASQAEARAAGLRGTPTLFLNGRYLALPDFSPAMLLHALEDEEEWQQHQGWEKD

Sequences:

>Translated_311_residues
MTVSRSILLAALAALGLAGLPACKTAAPAPGAPAAAAPAGAAPAATADPLAGVDLDDLTPEQRAIVRDWASRAFCYCGCP
HTVTSCLRTHQPCKHAARMARLAARLVAAGAGPSALPGLVDDYYASFDRRMALATDGFGPPLGDPAAPVTLLEFSDFTCP
FCRGLRPALERFVEEHPGRVKLVFKPFPIEAHPGALEAAQAGEWARDQGIFWPLHDALFEAAAPLDVDAIAAAAREAGGD
AGDLRDALASRKYLDKIRASQAEARAAGLRGTPTLFLNGRYLALPDFSPAMLLHALEDEEEWQQHQGWEKD
>Mature_310_residues
TVSRSILLAALAALGLAGLPACKTAAPAPGAPAAAAPAGAAPAATADPLAGVDLDDLTPEQRAIVRDWASRAFCYCGCPH
TVTSCLRTHQPCKHAARMARLAARLVAAGAGPSALPGLVDDYYASFDRRMALATDGFGPPLGDPAAPVTLLEFSDFTCPF
CRGLRPALERFVEEHPGRVKLVFKPFPIEAHPGALEAAQAGEWARDQGIFWPLHDALFEAAAPLDVDAIAAAAREAGGDA
GDLRDALASRKYLDKIRASQAEARAAGLRGTPTLFLNGRYLALPDFSPAMLLHALEDEEEWQQHQGWEKD

Specific function: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons [H]

COG id: COG1651

COG function: function code O; Protein-disulfide isomerase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001853
- InterPro:   IPR023171
- InterPro:   IPR004670
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF01323 DSBA; PF06965 Na_H_antiport_1 [H]

EC number: NA

Molecular weight: Translated: 32805; Mature: 32674

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVSRSILLAALAALGLAGLPACKTAAPAPGAPAAAAPAGAAPAATADPLAGVDLDDLTP
CCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCH
EQRAIVRDWASRAFCYCGCPHTVTSCLRTHQPCKHAARMARLAARLVAAGAGPSALPGLV
HHHHHHHHHHHCCEEEECCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCHHCCHHH
DDYYASFDRRMALATDGFGPPLGDPAAPVTLLEFSDFTCPFCRGLRPALERFVEEHPGRV
HHHHHHHHHHHHEECCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCEE
KLVFKPFPIEAHPGALEAAQAGEWARDQGIFWPLHDALFEAAAPLDVDAIAAAAREAGGD
EEEEECCCCCCCCCCHHHHHCCCCHHHCCCEEHHHHHHHHHCCCCCHHHHHHHHHHCCCC
AGDLRDALASRKYLDKIRASQAEARAAGLRGTPTLFLNGRYLALPDFSPAMLLHALEDEE
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCEEEECCCCCHHHHHHHHCCHH
EWQQHQGWEKD
HHHHHCCCCCC
>Mature Secondary Structure 
TVSRSILLAALAALGLAGLPACKTAAPAPGAPAAAAPAGAAPAATADPLAGVDLDDLTP
CCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCH
EQRAIVRDWASRAFCYCGCPHTVTSCLRTHQPCKHAARMARLAARLVAAGAGPSALPGLV
HHHHHHHHHHHCCEEEECCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCHHCCHHH
DDYYASFDRRMALATDGFGPPLGDPAAPVTLLEFSDFTCPFCRGLRPALERFVEEHPGRV
HHHHHHHHHHHHEECCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCEE
KLVFKPFPIEAHPGALEAAQAGEWARDQGIFWPLHDALFEAAAPLDVDAIAAAAREAGGD
EEEEECCCCCCCCCCHHHHHCCCCHHHCCCEEHHHHHHHHHCCCCCHHHHHHHHHHCCCC
AGDLRDALASRKYLDKIRASQAEARAAGLRGTPTLFLNGRYLALPDFSPAMLLHALEDEE
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCEEEECCCCCHHHHHHHHCCHH
EWQQHQGWEKD
HHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA