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The map label for this gene is lolC [H]

Identifier: 220918652

GI number: 220918652

Start: 3977141

End: 3978358

Strand: Reverse

Name: lolC [H]

Synonym: A2cp1_3560

Alternate gene names: 220918652

Gene position: 3978358-3977141 (Counterclockwise)

Preceding gene: 220918653

Following gene: 220918651

Centisome position: 79.1

GC content: 74.63

Gene sequence:

>1218_bases
GTGCCCTTTGAGCTGTTCGTCGCGCTGCGGTTCCTGCGCGAGGGCCGCGCCCAGACCGCGCTGGTGCTGGGCGGCGCCAC
GGTGGGCGTGGGGGTGATCGTCTTCCTGACCGCGCTCATCGGCGGGCTCCAGGCGACGCTCGTGGAGCAGACGCTCGGGT
CGCAGGCGCACGTGGTGCTGCGCCGGCCCGAGCGCGTCCCGAAGGCGCTGCCGCCCGGGCCGGGCGAGGCGCTGGCCGCC
CTGGTGGAGAAGATCCCGGAGCGCGATCGCTCGGTGGAGCAGTGGCCGGAGGTGCTCGCGGTGGTCCGGGGCGCGCCGGG
CGTGGTCTCGGCCACGCCGACCGCGGCGGGCTCGGCGTTCGCGAGCCGGGCCGGGGTGTCGCGCGCGGTGGCGCTGCGCG
GGGTCGAGCCCGGGAGCTTCGACGGCGTGATCCAGATGTCGCGGCGCATGAAGGCGGGCGCGTTCCGGGTCGGCGGCGAG
GAGGCGGTGATCGGGGCGGTGCTCGCGGACGAGCTGGGGCTCGCGGTGGGCGACAAGCTCCGGATCACCAGCGCCGAGTC
GCGCTCCGACCTGTTCACCGTGGCCGGCATCTTCGACCTGGGCAGCCGGGACGTGAACCAGCGGTGGGTGCTGGTCTCGC
TGCGCGCGGCGCAGACGCTGCTCGATCTCCAGGGTGGCATCACCGGGATCGAGCTGAAGGTGCGGGACCCGTTCGCCGCC
GAGCGCGTGGCGCGGTCGCTCGCGGCGCGGACCGGCCTGCTGGCCGAGAGCTGGATGCAGCTGAACCAGCAGCTCCTCAC
GGCGCTGCGCTCCCAGAGCGCCTCCTCCCTGCTCATCCAGTCCTTCGTGGTGCTGGCGGTGGCGCTCGGGATCGCGAGCG
TGCTGGGCATCTCGGTGATCCAGCGGTCGCGCGAGATCGGCATCCTGAAGGCCACCGGCACCACCACCGGCACCGTGCTC
CGCATCTTCCTCATCGAGGGCGCGCTGGTCGGCGGGGCCGGCTCGATCCTCGGCGCGCTGCTCGGCACGGCCATGTCGCT
CGCGTTCGCGACGCTGGTGCGGAACCCCTACGGCGAGGCGCTGTTCCCGGTGGAGCTGACCCCGGGGCTGTTCCTGCTGG
CGTCGGCGGTCGCGGTCGGGACCGGCCTGGTGGCCGCCGCCTACCCGGCGCGGCGCGCGGCGAAGCTCGACCCGGCGGTG
GTGATCCGGTATGGCTGA

Upstream 100 bases:

>100_bases
GGTGGCCTCGCGGCGGGCGACGAGGTGCTGGCGCCCTCCGCCGCGGTGGCGGAGGGGAGCCGCGTGCGGGTGCGCCGCCT
GCCCGGGCCGGAGCTGGGCC

Downstream 100 bases:

>100_bases
GCCGGTGGCCACGGCGACGGTGGAGCTCTCCGGCGTCCGCAAGGACTACGTGGCCGGCTCGGTGGTCACGCCGGTGCTGC
ACGGCGTGGACCTCGAGGTG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 405; Mature: 404

Protein sequence:

>405_residues
MPFELFVALRFLREGRAQTALVLGGATVGVGVIVFLTALIGGLQATLVEQTLGSQAHVVLRRPERVPKALPPGPGEALAA
LVEKIPERDRSVEQWPEVLAVVRGAPGVVSATPTAAGSAFASRAGVSRAVALRGVEPGSFDGVIQMSRRMKAGAFRVGGE
EAVIGAVLADELGLAVGDKLRITSAESRSDLFTVAGIFDLGSRDVNQRWVLVSLRAAQTLLDLQGGITGIELKVRDPFAA
ERVARSLAARTGLLAESWMQLNQQLLTALRSQSASSLLIQSFVVLAVALGIASVLGISVIQRSREIGILKATGTTTGTVL
RIFLIEGALVGGAGSILGALLGTAMSLAFATLVRNPYGEALFPVELTPGLFLLASAVAVGTGLVAAAYPARRAAKLDPAV
VIRYG

Sequences:

>Translated_405_residues
MPFELFVALRFLREGRAQTALVLGGATVGVGVIVFLTALIGGLQATLVEQTLGSQAHVVLRRPERVPKALPPGPGEALAA
LVEKIPERDRSVEQWPEVLAVVRGAPGVVSATPTAAGSAFASRAGVSRAVALRGVEPGSFDGVIQMSRRMKAGAFRVGGE
EAVIGAVLADELGLAVGDKLRITSAESRSDLFTVAGIFDLGSRDVNQRWVLVSLRAAQTLLDLQGGITGIELKVRDPFAA
ERVARSLAARTGLLAESWMQLNQQLLTALRSQSASSLLIQSFVVLAVALGIASVLGISVIQRSREIGILKATGTTTGTVL
RIFLIEGALVGGAGSILGALLGTAMSLAFATLVRNPYGEALFPVELTPGLFLLASAVAVGTGLVAAAYPARRAAKLDPAV
VIRYG
>Mature_404_residues
PFELFVALRFLREGRAQTALVLGGATVGVGVIVFLTALIGGLQATLVEQTLGSQAHVVLRRPERVPKALPPGPGEALAAL
VEKIPERDRSVEQWPEVLAVVRGAPGVVSATPTAAGSAFASRAGVSRAVALRGVEPGSFDGVIQMSRRMKAGAFRVGGEE
AVIGAVLADELGLAVGDKLRITSAESRSDLFTVAGIFDLGSRDVNQRWVLVSLRAAQTLLDLQGGITGIELKVRDPFAAE
RVARSLAARTGLLAESWMQLNQQLLTALRSQSASSLLIQSFVVLAVALGIASVLGISVIQRSREIGILKATGTTTGTVLR
IFLIEGALVGGAGSILGALLGTAMSLAFATLVRNPYGEALFPVELTPGLFLLASAVAVGTGLVAAAYPARRAAKLDPAVV
IRYG

Specific function: Part of an ATP-dependent transport system responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprotein) and

COG id: COG4591

COG function: function code M; ABC-type transport system, involved in lipoprotein release, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787362, Length=437, Percent_Identity=25.629290617849, Blast_Score=105, Evalue=6e-24,
Organism=Escherichia coli, GI1787360, Length=429, Percent_Identity=25.6410256410256, Blast_Score=86, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003838
- InterPro:   IPR011925 [H]

Pfam domain/function: PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 42009; Mature: 41877

Theoretical pI: Translated: 10.86; Mature: 10.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPFELFVALRFLREGRAQTALVLGGATVGVGVIVFLTALIGGLQATLVEQTLGSQAHVVL
CCHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
RRPERVPKALPPGPGEALAALVEKIPERDRSVEQWPEVLAVVRGAPGVVSATPTAAGSAF
ECCHHCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCEECCCCCCCHHH
ASRAGVSRAVALRGVEPGSFDGVIQMSRRMKAGAFRVGGEEAVIGAVLADELGLAVGDKL
HHHHCCHHHHHEECCCCCCCHHHHHHHHHHHCCCEECCCCHHHHHHHHHHHHCHHCCCCE
RITSAESRSDLFTVAGIFDLGSRDVNQRWVLVSLRAAQTLLDLQGGITGIELKVRDPFAA
EEECCCCCCCCEEEEHHHHCCCCCCCCEEEEEEHHHHHHHHHHHCCCEEEEEEECCCHHH
ERVARSLAARTGLLAESWMQLNQQLLTALRSQSASSLLIQSFVVLAVALGIASVLGISVI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
QRSREIGILKATGTTTGTVLRIFLIEGALVGGAGSILGALLGTAMSLAFATLVRNPYGEA
HHHHCCEEEEECCCCHHHHHHHHHHHCHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCC
LFPVELTPGLFLLASAVAVGTGLVAAAYPARRAAKLDPAVVIRYG
EEEEECCCHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCEEEEECC
>Mature Secondary Structure 
PFELFVALRFLREGRAQTALVLGGATVGVGVIVFLTALIGGLQATLVEQTLGSQAHVVL
CHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
RRPERVPKALPPGPGEALAALVEKIPERDRSVEQWPEVLAVVRGAPGVVSATPTAAGSAF
ECCHHCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCEECCCCCCCHHH
ASRAGVSRAVALRGVEPGSFDGVIQMSRRMKAGAFRVGGEEAVIGAVLADELGLAVGDKL
HHHHCCHHHHHEECCCCCCCHHHHHHHHHHHCCCEECCCCHHHHHHHHHHHHCHHCCCCE
RITSAESRSDLFTVAGIFDLGSRDVNQRWVLVSLRAAQTLLDLQGGITGIELKVRDPFAA
EEECCCCCCCCEEEEHHHHCCCCCCCCEEEEEEHHHHHHHHHHHCCCEEEEEEECCCHHH
ERVARSLAARTGLLAESWMQLNQQLLTALRSQSASSLLIQSFVVLAVALGIASVLGISVI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
QRSREIGILKATGTTTGTVLRIFLIEGALVGGAGSILGALLGTAMSLAFATLVRNPYGEA
HHHHCCEEEEECCCCHHHHHHHHHHHCHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCC
LFPVELTPGLFLLASAVAVGTGLVAAAYPARRAAKLDPAVVIRYG
EEEEECCCHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]