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The map label for this gene is tig [H]

Identifier: 220918592

GI number: 220918592

Start: 3914337

End: 3915626

Strand: Reverse

Name: tig [H]

Synonym: A2cp1_3500

Alternate gene names: 220918592

Gene position: 3915626-3914337 (Counterclockwise)

Preceding gene: 220918594

Following gene: 220918591

Centisome position: 77.86

GC content: 70.39

Gene sequence:

>1290_bases
ATGAAGATCCAGGTCGAAACGGTCTCCCCCGTCGAGCGGAAGGTCACCATCGAGGTGGACCCCGATCGCGTCGCCAAGGA
GCTCGATCGCGCGTACGCCAGCCTGTCGCGGCGGGTGAAGCTGCGCGGCTTCCGGCCCGGCAAGGCGCCGCGCAAGGTCC
TGGAGCGCCAGTTCAAGACCGAGGTGGAGGGGGAGGTCGCCGAGCGGATCGTCACCGAGACGTTCACCGAGGCGGTCCGG
GTCGAGTCGCTGCCGGTGGTGGCGCCGCCCAGCGTCTCCATCACCGACGGTGTGGCCGAGGGGAAGCCCATGCGCTACTC
GGCGCGCGTCGAGGTGAAGCCGAAGCTCGAGCCCAAGGACTACAAGGGCCTCGAGGTGACGCGGAAGCCGCCCGAGGTCA
CCGACGAGGCGGTCTCCGGCGAGCTGACGAAGATCCAGGACTCGATGGCCCAGCTCGTGCCCGTCGAGGGGCGCTTCGAG
GCCCAGGAGGGCGACTGGGCGGTGATCGATCACGAGGGCACCATCGACGGGAAGCCGTTCGATGGCAGCACGGCCGAGGG
AGTGACCGTCAAGGTGGCGCCGGGTCCGATCACCGAAGGCAACGTCGAGGCCCTCAAGGGCAAGAAGATCGGCGACGTGG
TCGAGCTCGACGAGCCGTTCCCGGCCGACCACCGCGACGAGGCGCTGCGCGGCAAGACGGCGCACATGAAGGTCACGCTG
AAGGCGCTGAAGGCCCGCCAGGCGCCGTCGCTCGACGACGCGCTCGCCAAGGACCTGGGCATCGAGGGCGTCGAGACCCT
GGACGCGCTGCGCGCCCGGATCCGGTCCGACCTGGAGAAGCGCGAGAAGCGGCGCGCCGAGTCGGAGCTGAAGGACGCGC
TGGTGAAGGCGGCGCTGGCCCGGAACGAGTTCGAGGTGCCGCCGGCGCTGGTGGAGCGCGCCATCGACACCATGCTCGAG
GGCGCGGCCGAGCGGTTCGCCCGCCAGGGGATCGACATCCGCCAGCTCCAGCTCGACGTGTCGCGCATGCGCGCCGATCT
GCGCGAGCAGGCGCTCCTCCAGGTGCGCGGCGCCCTGCTGCTCGAGGCCATCGCGGACGCCGAGAAGATCGAGGTCACCG
AGGAGGACCTGGAGGCCGAGGCGGCCCGCATCGCGGACGAGCTGGGGATGCCCCTGGCGAAGGTCCAGCAGCAGACGCGC
GGCAAGGACGCGCGCGAGGCGCTAAAGAACAGGATCAGGGAGGAGAAGGCGCTCTCGCTGCTCTCCTCCGCTGCAACCAT
CCAGCAGTAG

Upstream 100 bases:

>100_bases
TCGAGCCCCTCCCCGCCCACTTCACCCTTGACCCGCCACCGGCGGGCACGTAGCACTAGCCGATTTCCCCGCCCACACAC
CCGCAAAGGTCGAACAGGAC

Downstream 100 bases:

>100_bases
CGAACGCCGGAGACCCGCGATGCCCTACATCCCCATGCCGTACGTGGTCGAGCAGACCCACCGCGGCGAGCGCAGCTACG
ACATCTACTCGCGGCTCCTG

Product: trigger factor

Products: peptidylproline (omega=0)

Alternate protein names: TF [H]

Number of amino acids: Translated: 429; Mature: 429

Protein sequence:

>429_residues
MKIQVETVSPVERKVTIEVDPDRVAKELDRAYASLSRRVKLRGFRPGKAPRKVLERQFKTEVEGEVAERIVTETFTEAVR
VESLPVVAPPSVSITDGVAEGKPMRYSARVEVKPKLEPKDYKGLEVTRKPPEVTDEAVSGELTKIQDSMAQLVPVEGRFE
AQEGDWAVIDHEGTIDGKPFDGSTAEGVTVKVAPGPITEGNVEALKGKKIGDVVELDEPFPADHRDEALRGKTAHMKVTL
KALKARQAPSLDDALAKDLGIEGVETLDALRARIRSDLEKREKRRAESELKDALVKAALARNEFEVPPALVERAIDTMLE
GAAERFARQGIDIRQLQLDVSRMRADLREQALLQVRGALLLEAIADAEKIEVTEEDLEAEAARIADELGMPLAKVQQQTR
GKDAREALKNRIREEKALSLLSSAATIQQ

Sequences:

>Translated_429_residues
MKIQVETVSPVERKVTIEVDPDRVAKELDRAYASLSRRVKLRGFRPGKAPRKVLERQFKTEVEGEVAERIVTETFTEAVR
VESLPVVAPPSVSITDGVAEGKPMRYSARVEVKPKLEPKDYKGLEVTRKPPEVTDEAVSGELTKIQDSMAQLVPVEGRFE
AQEGDWAVIDHEGTIDGKPFDGSTAEGVTVKVAPGPITEGNVEALKGKKIGDVVELDEPFPADHRDEALRGKTAHMKVTL
KALKARQAPSLDDALAKDLGIEGVETLDALRARIRSDLEKREKRRAESELKDALVKAALARNEFEVPPALVERAIDTMLE
GAAERFARQGIDIRQLQLDVSRMRADLREQALLQVRGALLLEAIADAEKIEVTEEDLEAEAARIADELGMPLAKVQQQTR
GKDAREALKNRIREEKALSLLSSAATIQQ
>Mature_429_residues
MKIQVETVSPVERKVTIEVDPDRVAKELDRAYASLSRRVKLRGFRPGKAPRKVLERQFKTEVEGEVAERIVTETFTEAVR
VESLPVVAPPSVSITDGVAEGKPMRYSARVEVKPKLEPKDYKGLEVTRKPPEVTDEAVSGELTKIQDSMAQLVPVEGRFE
AQEGDWAVIDHEGTIDGKPFDGSTAEGVTVKVAPGPITEGNVEALKGKKIGDVVELDEPFPADHRDEALRGKTAHMKVTL
KALKARQAPSLDDALAKDLGIEGVETLDALRARIRSDLEKREKRRAESELKDALVKAALARNEFEVPPALVERAIDTMLE
GAAERFARQGIDIRQLQLDVSRMRADLREQALLQVRGALLLEAIADAEKIEVTEEDLEAEAARIADELGMPLAKVQQQTR
GKDAREALKNRIREEKALSLLSSAATIQQ

Specific function: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation [H]

COG id: COG0544

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Escherichia coli, GI1786640, Length=430, Percent_Identity=26.7441860465116, Blast_Score=154, Evalue=1e-38,

Paralogues:

None

Copy number: 1070 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 500 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 340 Molecules/Cell In: Growth-Phase, Mini

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000048
- InterPro:   IPR001179
- InterPro:   IPR005215
- InterPro:   IPR008880
- InterPro:   IPR008881 [H]

Pfam domain/function: PF00254 FKBP_C; PF05698 Trigger_C; PF05697 Trigger_N [H]

EC number: 5.2.1.8

Molecular weight: Translated: 47315; Mature: 47315

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: PS50096 IQ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIQVETVSPVERKVTIEVDPDRVAKELDRAYASLSRRVKLRGFRPGKAPRKVLERQFKT
CEEEEECCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
EVEGEVAERIVTETFTEAVRVESLPVVAPPSVSITDGVAEGKPMRYSARVEVKPKLEPKD
HHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCC
YKGLEVTRKPPEVTDEAVSGELTKIQDSMAQLVPVEGRFEAQEGDWAVIDHEGTIDGKPF
CCCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHCCCCCCEECCCCCEEEEECCCCCCCCCC
DGSTAEGVTVKVAPGPITEGNVEALKGKKIGDVVELDEPFPADHRDEALRGKTAHMKVTL
CCCCCCCEEEEECCCCCCCCCHHHHCCCCCCCEEECCCCCCCCCCHHHHCCCCHHHHHHH
KALKARQAPSLDDALAKDLGIEGVETLDALRARIRSDLEKREKRRAESELKDALVKAALA
HHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RNEFEVPPALVERAIDTMLEGAAERFARQGIDIRQLQLDVSRMRADLREQALLQVRGALL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LEAIADAEKIEVTEEDLEAEAARIADELGMPLAKVQQQTRGKDAREALKNRIREEKALSL
HHHHHCHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
LSSAATIQQ
HHHHHHHCC
>Mature Secondary Structure
MKIQVETVSPVERKVTIEVDPDRVAKELDRAYASLSRRVKLRGFRPGKAPRKVLERQFKT
CEEEEECCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
EVEGEVAERIVTETFTEAVRVESLPVVAPPSVSITDGVAEGKPMRYSARVEVKPKLEPKD
HHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCC
YKGLEVTRKPPEVTDEAVSGELTKIQDSMAQLVPVEGRFEAQEGDWAVIDHEGTIDGKPF
CCCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHCCCCCCEECCCCCEEEEECCCCCCCCCC
DGSTAEGVTVKVAPGPITEGNVEALKGKKIGDVVELDEPFPADHRDEALRGKTAHMKVTL
CCCCCCCEEEEECCCCCCCCCHHHHCCCCCCCEEECCCCCCCCCCHHHHCCCCHHHHHHH
KALKARQAPSLDDALAKDLGIEGVETLDALRARIRSDLEKREKRRAESELKDALVKAALA
HHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RNEFEVPPALVERAIDTMLEGAAERFARQGIDIRQLQLDVSRMRADLREQALLQVRGALL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LEAIADAEKIEVTEEDLEAEAARIADELGMPLAKVQQQTRGKDAREALKNRIREEKALSL
HHHHHCHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
LSSAATIQQ
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: peptidylproline (omega=180)

Specific reaction: peptidylproline (omega=180) = peptidylproline (omega=0)

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA