BacMap

Definition	Anaeromyxobacter dehalogenans 2CP-1 chromosome, complete genome.
Accession	NC_011891
Length	5,029,329

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The map label for this gene is fabG [H]

Identifier: 220918480

GI number: 220918480

Start: 3775718

End: 3776368

Strand: Reverse

Name: fabG [H]

Synonym: A2cp1_3385

Alternate gene names: 220918480

Gene position: 3776368-3775718 (Counterclockwise)

Preceding gene: 220918484

Following gene: 220918479

Centisome position: 75.09

GC content: 72.66

Gene sequence:

>651_bases
GTGAACTACGTGGCCAGCCGCGCCAAGGGGCAGCACGTGGTGGACGAGATCGTCGCGGCGGGCGGGCGGGCGATCCTCGT
CCGCGCCGACGCCACGGTCCGGTCGGAGGCCGAGGCGATGGTCCGCGGCGTCGAGGCGGAGCTCGGCCCCGTGGACATCC
TCGTCAACAACGCCTCCATCGGCTTTCCGATCGTCCCGTTCGCCGAGTACGCCTGGGAGGACTTCCAGCGGAAGGTCGAG
GGGGAGGCGAAGGCCAGCTTCTTCACCTGCCAGGCGGTGATCCCCGGCATGATCCAGCGGCGTAGCGGCTGCATCGTGAA
CGTGAGCAGCACGCTGTCGCGGTTCCCGGGCCCCGGGTTCGTCGCGCACTCGTGCGCCAAGTCCGGGCTCGACGGGTTCT
CCAGGGCGCTCGCCCTCGAGCTGGGGCCGCACGGCATCCGCGTGAACGTCGTCGCGCCCGGCCTCACCCTCACCGACGCG
ACGCGCGACCAGCCGGCGCAGTTCCACGAGGCGATCGCCGCGCACACGCCGCTCCGGCGGCTGGCCGAGCCGGAGGACAT
CGCCGGGGCCGTCGCCTTCCTCTGCTCCCCCGCGGCGCGGCACGTGACGGGCGTCTACCTGCCCGTGTGCGGCGGCGCGA
ACATGATGTAG

Upstream 100 bases:

>100_bases
ATCTGGATCATGGGACAAGATCGCCATCGTCACCGGCTCGAGCCGCGGCATCGGCGCCGCCATCGCCAAGGCGCTCGCCC
GCCAGGGCGCGAAGGTCGCG

Downstream 100 bases:

>100_bases
CGGAGCGCCGAGCATCCCGTGGGTGGGCGGGGCGATCTCCTGCCCGGCGCACCGGCCTGCCGCGGGCGGTCCTGCCGACG
CCCTCCCGACTCACCCGGTC

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 216; Mature: 216

Protein sequence:

>216_residues
MNYVASRAKGQHVVDEIVAAGGRAILVRADATVRSEAEAMVRGVEAELGPVDILVNNASIGFPIVPFAEYAWEDFQRKVE
GEAKASFFTCQAVIPGMIQRRSGCIVNVSSTLSRFPGPGFVAHSCAKSGLDGFSRALALELGPHGIRVNVVAPGLTLTDA
TRDQPAQFHEAIAAHTPLRRLAEPEDIAGAVAFLCSPAARHVTGVYLPVCGGANMM

Sequences:

>Translated_216_residues
MNYVASRAKGQHVVDEIVAAGGRAILVRADATVRSEAEAMVRGVEAELGPVDILVNNASIGFPIVPFAEYAWEDFQRKVE
GEAKASFFTCQAVIPGMIQRRSGCIVNVSSTLSRFPGPGFVAHSCAKSGLDGFSRALALELGPHGIRVNVVAPGLTLTDA
TRDQPAQFHEAIAAHTPLRRLAEPEDIAGAVAFLCSPAARHVTGVYLPVCGGANMM
>Mature_216_residues
MNYVASRAKGQHVVDEIVAAGGRAILVRADATVRSEAEAMVRGVEAELGPVDILVNNASIGFPIVPFAEYAWEDFQRKVE
GEAKASFFTCQAVIPGMIQRRSGCIVNVSSTLSRFPGPGFVAHSCAKSGLDGFSRALALELGPHGIRVNVVAPGLTLTDA
TRDQPAQFHEAIAAHTPLRRLAEPEDIAGAVAFLCSPAARHVTGVYLPVCGGANMM

Specific function: 7-Alpha-Dehydroxylation Of Cholic Acid, Yielding Deoxycholic Acid And Lithocholic Acid, Respectively. Highest Affinity With Taurochenodeoxycholic Acid. [C]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=219, Percent_Identity=35.1598173515982, Blast_Score=110, Evalue=9e-25,
Organism=Homo sapiens, GI40254992, Length=197, Percent_Identity=36.0406091370558, Blast_Score=101, Evalue=6e-22,
Organism=Homo sapiens, GI126723750, Length=172, Percent_Identity=36.6279069767442, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI7705925, Length=168, Percent_Identity=38.6904761904762, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI19923817, Length=199, Percent_Identity=28.643216080402, Blast_Score=86, Evalue=2e-17,
Organism=Homo sapiens, GI15277342, Length=144, Percent_Identity=32.6388888888889, Blast_Score=86, Evalue=2e-17,
Organism=Homo sapiens, GI5031737, Length=182, Percent_Identity=32.967032967033, Blast_Score=84, Evalue=8e-17,
Organism=Homo sapiens, GI10190704, Length=199, Percent_Identity=31.1557788944724, Blast_Score=81, Evalue=7e-16,
Organism=Homo sapiens, GI59889578, Length=199, Percent_Identity=26.6331658291457, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI4503301, Length=187, Percent_Identity=28.8770053475936, Blast_Score=68, Evalue=6e-12,
Organism=Homo sapiens, GI126723191, Length=101, Percent_Identity=35.6435643564356, Blast_Score=66, Evalue=3e-11,
Organism=Escherichia coli, GI1787905, Length=203, Percent_Identity=39.4088669950739, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI1787335, Length=214, Percent_Identity=34.5794392523364, Blast_Score=119, Evalue=1e-28,
Organism=Escherichia coli, GI2367175, Length=218, Percent_Identity=30.7339449541284, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1790717, Length=203, Percent_Identity=31.0344827586207, Blast_Score=104, Evalue=5e-24,
Organism=Escherichia coli, GI87082160, Length=168, Percent_Identity=36.3095238095238, Blast_Score=97, Evalue=9e-22,
Organism=Escherichia coli, GI1788459, Length=198, Percent_Identity=32.8282828282828, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI87082100, Length=214, Percent_Identity=29.4392523364486, Blast_Score=94, Evalue=7e-21,
Organism=Escherichia coli, GI1789208, Length=206, Percent_Identity=32.5242718446602, Blast_Score=94, Evalue=8e-21,
Organism=Escherichia coli, GI1789378, Length=222, Percent_Identity=27.9279279279279, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1786812, Length=180, Percent_Identity=31.6666666666667, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1787820, Length=187, Percent_Identity=27.807486631016, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI2367365, Length=165, Percent_Identity=33.3333333333333, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1789057, Length=224, Percent_Identity=27.6785714285714, Blast_Score=69, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17555706, Length=172, Percent_Identity=34.8837209302326, Blast_Score=86, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI71994604, Length=210, Percent_Identity=30.952380952381, Blast_Score=82, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI115534694, Length=166, Percent_Identity=32.5301204819277, Blast_Score=80, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI71994600, Length=199, Percent_Identity=31.1557788944724, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17561402, Length=174, Percent_Identity=31.6091954022989, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI25147288, Length=173, Percent_Identity=30.0578034682081, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17560332, Length=211, Percent_Identity=28.9099526066351, Blast_Score=77, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17562904, Length=182, Percent_Identity=29.6703296703297, Blast_Score=77, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI17560676, Length=218, Percent_Identity=28.8990825688073, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17559104, Length=204, Percent_Identity=27.4509803921569, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17562910, Length=229, Percent_Identity=29.2576419213974, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17560150, Length=205, Percent_Identity=28.2926829268293, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17565030, Length=214, Percent_Identity=31.3084112149533, Blast_Score=70, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17562990, Length=202, Percent_Identity=28.2178217821782, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17538480, Length=209, Percent_Identity=27.7511961722488, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17551412, Length=207, Percent_Identity=27.0531400966184, Blast_Score=68, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17508651, Length=213, Percent_Identity=25.3521126760563, Blast_Score=64, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6324126, Length=194, Percent_Identity=34.020618556701, Blast_Score=91, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6322861, Length=141, Percent_Identity=34.7517730496454, Blast_Score=67, Evalue=1e-12,
Organism=Drosophila melanogaster, GI21357041, Length=215, Percent_Identity=36.7441860465116, Blast_Score=116, Evalue=1e-26,
Organism=Drosophila melanogaster, GI28571526, Length=215, Percent_Identity=34.4186046511628, Blast_Score=110, Evalue=8e-25,
Organism=Drosophila melanogaster, GI23397609, Length=199, Percent_Identity=33.1658291457286, Blast_Score=103, Evalue=9e-23,
Organism=Drosophila melanogaster, GI24644337, Length=174, Percent_Identity=36.7816091954023, Blast_Score=99, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24643142, Length=175, Percent_Identity=36.5714285714286, Blast_Score=95, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24644339, Length=197, Percent_Identity=32.48730964467, Blast_Score=94, Evalue=8e-20,
Organism=Drosophila melanogaster, GI24639444, Length=166, Percent_Identity=33.1325301204819, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI21355319, Length=169, Percent_Identity=30.1775147928994, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI21355631, Length=114, Percent_Identity=33.3333333333333, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI18859837, Length=210, Percent_Identity=30.952380952381, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 22780; Mature: 22780

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYVASRAKGQHVVDEIVAAGGRAILVRADATVRSEAEAMVRGVEAELGPVDILVNNASI
CCCCCCCCCCHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCEEEEEECCCC
GFPIVPFAEYAWEDFQRKVEGEAKASFFTCQAVIPGMIQRRSGCIVNVSSTLSRFPGPGF
CCCCCHHHHHHHHHHHHHHCCCHHHHHEEHHHHHHHHHHHCCCCEEEEHHHHHHCCCCCH
VAHSCAKSGLDGFSRALALELGPHGIRVNVVAPGLTLTDATRDQPAQFHEAIAAHTPLRR
HHHHHHHHCHHHHHHHEEEEECCCCEEEEEEECCEEEECCCCCCHHHHHHHHHHHCCHHH
LAEPEDIAGAVAFLCSPAARHVTGVYLPVCGGANMM
HCCCHHHHHHHHHHHCHHHHHHEEEEEEECCCCCCC
>Mature Secondary Structure
MNYVASRAKGQHVVDEIVAAGGRAILVRADATVRSEAEAMVRGVEAELGPVDILVNNASI
CCCCCCCCCCHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCEEEEEECCCC
GFPIVPFAEYAWEDFQRKVEGEAKASFFTCQAVIPGMIQRRSGCIVNVSSTLSRFPGPGF
CCCCCHHHHHHHHHHHHHHCCCHHHHHEEHHHHHHHHHHHCCCCEEEEHHHHHHCCCCCH
VAHSCAKSGLDGFSRALALELGPHGIRVNVVAPGLTLTDATRDQPAQFHEAIAAHTPLRR
HHHHHHHHCHHHHHHHEEEEECCCCEEEEEEECCEEEECCCCCCHHHHHHHHHHHCCHHH
LAEPEDIAGAVAFLCSPAARHVTGVYLPVCGGANMM
HCCCHHHHHHHHHHHCHHHHHHEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA