Click here to switch to the map view.

The map label for this gene is tolC [C]

Identifier: 220918400

GI number: 220918400

Start: 3679314

End: 3680636

Strand: Reverse

Name: tolC [C]

Synonym: A2cp1_3304

Alternate gene names: 220918400

Gene position: 3680636-3679314 (Counterclockwise)

Preceding gene: 220918407

Following gene: 220918399

Centisome position: 73.18

GC content: 79.59

Gene sequence:

>1323_bases
GTGAACACGCCGATCCTCCTCGCGCTCCTCCTCGCCACGCCGGGCGGTACCCCGGCGGCGCCCGCCGCCTCGCCGGCCGC
GCCGCCCGACGCCGCCGTCGCCGAGCTGACGCTCGAGGCCGCCCTCCGCGAGCTCGACGCGCAGAGCCTGACCCTGGCGC
AGGCGCGCAGCCGCGCCGACGAGGCGGGCGCGCTCGTGCGTCAGTCCGCCGCCGCGCTCCTCCCCACGCTCACCGCCCAG
GGCACCTATCTGAGGAACAGCGAGGGCGTCACGCTGGCGCTCCCGGGCGGCCCCGAGCGCGTCATCCAGCCGGACGAGTC
GCTGAGCGTGACCGCCACCGCGCGCGTCCCGCTGCTCGTCCCCACCGCCTGGTTCGACCTCGCCGCCGCGCGCGACGCGG
CCCGCGCCGAGGATCTCGGCGCCGAGGCCACCCGGCGCACGCTCCGCACCGGCCTGGCGCAGTCGGCGCACGGTGCCGCC
TCGGCGGAGGAGGTGGTGGCCGCCTCCGAGCGCGCCGTCGAGAGCGCGGCCGAGCTGGTGCGGAGCGCGGAGCGCCGCGT
GGCCGCCGGGACCGCGGCGCCGCTCGACGTGCTGAAGTCGCGCACGGAGCAGGTCCGGCGCGAGAGCGACCTGGTGTCCG
CGCGCGCCGGCCTGGAGCGGGCGCGGCTGGCGCTCGGGATCCTGCTCGGGCGGAGGGATCCGGTCCGGGTGGTGGTGCCG
GACGGCACCACGGCGCCCGCGCCGGAGCTCGACGTTCCGGCCGAGGCGCTGGCGGGCGAGGCGCTCGAGCACCGGCCGGA
GATCGCCGCGCAGGACGCGCGGGTGGCGGCGGCCGAGTCCGGCGTCCGCTCCGCCTGGGCGCGCCTCGCCCCGCAGCTCT
CCGCCTCCGGGTCCGCGTTCGCGGCGGACACCCCCTACGTCTCCGGCGAGAAGGACGGCTGGCGGGTGACGCTCGACCTC
ACCTGGCAGCTCTACGACGGCGGCTTCCGGTACGGGAAGCGCCGCCAGGCGGAGGCCCAGGCCGCCGGCGCGCGCGCCGG
CGCGGAGGCGCAGCGGCTGGCGGTGCGCCAGGAGGTGGAGGACGGCCGGCGCGACCTGCGCGTGGCGCGCGAGCGGCTCC
GCCTGGCCGACACGCAGTCGCGGCTGGCCGGCGAGACGGCCGCGTCGGCGCGCCGGTCCTTCGAGGCGGGGATCGCGTCG
AGCCTCGACGTGATCGACGCGAACGACCGCCAGTACCTGGCCGAGATCGGCCTCGCCGACGCGCGCGCGCGGCTCGCGCA
GGCGCGGCTCGCGCTCGGGCGCGCGCTGGGGCGGGACCTGTAG

Upstream 100 bases:

>100_bases
GAAACCGCCGCCGCGGCGCGATCCCGCGCGCCGGCACCGTCCTTGCTCTCCTCCGCGCCCGGCGGCGCCGTCCCCCCCGC
GCCGCCCCGGAGAACGCACC

Downstream 100 bases:

>100_bases
CGCCGGGGGCGGCCATGCGCGCGGCGGCGACCCTGGCGCGGCGGCGGGTGGGCTCCGGCCCGCCGCTGCCGGAGCGCATC
CAGCGGGAGGAGTTCTCCAG

Product: outer membrane efflux protein

Products: NA

Alternate protein names: Outer Membrane Efflux Protein Domain Protein; Outer Membrane Efflux Family Protein

Number of amino acids: Translated: 440; Mature: 440

Protein sequence:

>440_residues
MNTPILLALLLATPGGTPAAPAASPAAPPDAAVAELTLEAALRELDAQSLTLAQARSRADEAGALVRQSAAALLPTLTAQ
GTYLRNSEGVTLALPGGPERVIQPDESLSVTATARVPLLVPTAWFDLAAARDAARAEDLGAEATRRTLRTGLAQSAHGAA
SAEEVVAASERAVESAAELVRSAERRVAAGTAAPLDVLKSRTEQVRRESDLVSARAGLERARLALGILLGRRDPVRVVVP
DGTTAPAPELDVPAEALAGEALEHRPEIAAQDARVAAAESGVRSAWARLAPQLSASGSAFAADTPYVSGEKDGWRVTLDL
TWQLYDGGFRYGKRRQAEAQAAGARAGAEAQRLAVRQEVEDGRRDLRVARERLRLADTQSRLAGETAASARRSFEAGIAS
SLDVIDANDRQYLAEIGLADARARLAQARLALGRALGRDL

Sequences:

>Translated_440_residues
MNTPILLALLLATPGGTPAAPAASPAAPPDAAVAELTLEAALRELDAQSLTLAQARSRADEAGALVRQSAAALLPTLTAQ
GTYLRNSEGVTLALPGGPERVIQPDESLSVTATARVPLLVPTAWFDLAAARDAARAEDLGAEATRRTLRTGLAQSAHGAA
SAEEVVAASERAVESAAELVRSAERRVAAGTAAPLDVLKSRTEQVRRESDLVSARAGLERARLALGILLGRRDPVRVVVP
DGTTAPAPELDVPAEALAGEALEHRPEIAAQDARVAAAESGVRSAWARLAPQLSASGSAFAADTPYVSGEKDGWRVTLDL
TWQLYDGGFRYGKRRQAEAQAAGARAGAEAQRLAVRQEVEDGRRDLRVARERLRLADTQSRLAGETAASARRSFEAGIAS
SLDVIDANDRQYLAEIGLADARARLAQARLALGRALGRDL
>Mature_440_residues
MNTPILLALLLATPGGTPAAPAASPAAPPDAAVAELTLEAALRELDAQSLTLAQARSRADEAGALVRQSAAALLPTLTAQ
GTYLRNSEGVTLALPGGPERVIQPDESLSVTATARVPLLVPTAWFDLAAARDAARAEDLGAEATRRTLRTGLAQSAHGAA
SAEEVVAASERAVESAAELVRSAERRVAAGTAAPLDVLKSRTEQVRRESDLVSARAGLERARLALGILLGRRDPVRVVVP
DGTTAPAPELDVPAEALAGEALEHRPEIAAQDARVAAAESGVRSAWARLAPQLSASGSAFAADTPYVSGEKDGWRVTLDL
TWQLYDGGFRYGKRRQAEAQAAGARAGAEAQRLAVRQEVEDGRRDLRVARERLRLADTQSRLAGETAASARRSFEAGIAS
SLDVIDANDRQYLAEIGLADARARLAQARLALGRALGRDL

Specific function: Required For Proper Expression Of Outer Membrane Protein Genes Such As Ompf, Nmpc, Protein 2, Hemolysin, Colicin V, Or Colicin E1. May Be Specialized For Signal Sequence Independent, Extracellular Secretion In Gram-Negative Bacteria. [C]

COG id: COG1538

COG function: function code MU; Outer membrane protein

Gene ontology:

Cell location: Outer Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 240 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 46006; Mature: 46006

Theoretical pI: Translated: 5.44; Mature: 5.44

Prosite motif: PS00430 TONB_DEPENDENT_REC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.2 %Met     (Translated Protein)
0.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.2 %Met     (Mature Protein)
0.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTPILLALLLATPGGTPAAPAASPAAPPDAAVAELTLEAALRELDAQSLTLAQARSRAD
CCCHHEEHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHH
EAGALVRQSAAALLPTLTAQGTYLRNSEGVTLALPGGPERVIQPDESLSVTATARVPLLV
HHHHHHHHHHHHHHHHHCCCCCEEECCCCEEEEECCCCHHCCCCCCCCEEEEEECCCEEE
PTAWFDLAAARDAARAEDLGAEATRRTLRTGLAQSAHGAASAEEVVAASERAVESAAELV
CHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
RSAERRVAAGTAAPLDVLKSRTEQVRRESDLVSARAGLERARLALGILLGRRDPVRVVVP
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEC
DGTTAPAPELDVPAEALAGEALEHRPEIAAQDARVAAAESGVRSAWARLAPQLSASGSAF
CCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCHHHCCCCCEE
AADTPYVSGEKDGWRVTLDLTWQLYDGGFRYGKRRQAEAQAAGARAGAEAQRLAVRQEVE
ECCCCCCCCCCCCEEEEEEEEEEEECCCHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHH
DGRRDLRVARERLRLADTQSRLAGETAASARRSFEAGIASSLDVIDANDRQYLAEIGLAD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCHHHHHHHCHHH
ARARLAQARLALGRALGRDL
HHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNTPILLALLLATPGGTPAAPAASPAAPPDAAVAELTLEAALRELDAQSLTLAQARSRAD
CCCHHEEHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHH
EAGALVRQSAAALLPTLTAQGTYLRNSEGVTLALPGGPERVIQPDESLSVTATARVPLLV
HHHHHHHHHHHHHHHHHCCCCCEEECCCCEEEEECCCCHHCCCCCCCCEEEEEECCCEEE
PTAWFDLAAARDAARAEDLGAEATRRTLRTGLAQSAHGAASAEEVVAASERAVESAAELV
CHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
RSAERRVAAGTAAPLDVLKSRTEQVRRESDLVSARAGLERARLALGILLGRRDPVRVVVP
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEC
DGTTAPAPELDVPAEALAGEALEHRPEIAAQDARVAAAESGVRSAWARLAPQLSASGSAF
CCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCHHHCCCCCEE
AADTPYVSGEKDGWRVTLDLTWQLYDGGFRYGKRRQAEAQAAGARAGAEAQRLAVRQEVE
ECCCCCCCCCCCCEEEEEEEEEEEECCCHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHH
DGRRDLRVARERLRLADTQSRLAGETAASARRSFEAGIASSLDVIDANDRQYLAEIGLAD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCHHHHHHHCHHH
ARARLAQARLALGRALGRDL
HHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA